Evidence-Based GI: An ACG Publication and Podcast

American College of Gastroenterology

  • 10 minutes 35 seconds
    Hot Take: Can We Lengthen Surveillance Intervals After EMR With Margin Thermal Ablation?
    Margaret J. Zhou, MD, MS and Timothy Yen, MD discuss "Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence," by O'Sullivan T, Mandarino FV, Gauci JL, et al. Gut. 2024 Dec 10;74(1):67-74.
    14 January 2025, 4:00 pm
  • 9 minutes 15 seconds
    Redefining Risks in CDH1 Hereditary Diffuse Gastric Cancer
    Margaret J. Zhou, MD, MS and Timothy Yen, MD discuss "Germline CDH1 variants and lifetime cancer risk,” by Ryan CE, Fasaye G, Gallanis AF, et al. JAMA. 2024;332(9):722–729.
    14 January 2025, 4:00 pm
  • 17 minutes 45 seconds
    The Edge of a New Frontier: Anti-TL1A Monoclonal Antibodies for Ulcerative Colitis
    Philip Schoenfeld, MD, MSEd, MSc (Epi) and Bharati Kochar, MD, MS discuss “Phase 2 Trial of Anti-TL1A Monoclonal Antibody Tulisokibart for Ulcerative Colitis,” by Sands BE, Feagan BG, Biroulet LP, et al. N Engl J Med. 2024; 391: 1119-29.
    11 December 2024, 4:00 pm
  • 13 minutes 6 seconds
    Cold vs Hot Snare Resection of Large Polyps: A Cooler, Safer Approach for Large Colorectal Polyps
    Philip Schoenfeld, MD, MSEd, MSc (Epi) and Ahmad Abu-Heija, MBBS discuss “Cold Versus Hot Snare Endoscopic Resection of Large Nonpedunculated Colorectal Polyps: Randomized Controlled German CHRONICLE Trial,” by Steinbrück I, Ebigbo A, Kuellmer A, et al. Gastroenterology. 2024 Sep;167(4):764-777
    11 December 2024, 4:00 pm
  • 13 minutes 26 seconds
    Combination Therapy as Primary Prophylaxis for High-Risk Esophageal Varices
    Philip Schoenfeld, MD, MSEd, MSc (Epi) discusses “Combination of Carvedilol with Variceal Band Ligation in Prevention of First Variceal Bleed in Child-Turcotte-Pugh B and C Cirrhosis with High-Risk Oesophageal Varices: the ‘CAVARLY’ Trial,” by Tevethia HV, Pande A, Vijayaraghavan R, et al. Gut. 2024; 73: 1844-53.
    11 December 2024, 4:00 pm
  • 12 minutes 27 seconds
    Long Term Efficacy and Safety of Dupilumab for Eosinophilic Esophagitis
    Philip Schoenfeld, MD, MSEd, MSc (Epi) and Swathi Eluri, MD, MS discuss “Efficacy and safety of dupilumab up to 52 weeks in adults and adolescents with eosinophilic oesophagitis (LIBERTY EoE TREET study): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial,” by Summarizing Rothenber M, Dellon E, Collins M, et al. Lancet Gastroenterol Hep. 2023; 9: 990-1004
    11 December 2024, 4:00 pm
  • 19 minutes 4 seconds
    Subcutaneous Infliximab for Maintenance of IBD Remission: Added Convenience with Potential for Improved Efficacy?
    Philip Schoenfeld, MD, MSEd, MSc (Epi) and Elie S. Al Kazzi, MD, MPH discuss “Subcutaneous Infliximab (CT-P13 SC) as Maintenance Therapy for Inflammatory Bowel Disease: Two Randomized Phase 3 Trials (LIBERTY),” Gastroenterology. 2024;167:919–933.
    20 November 2024, 4:00 pm
  • 14 minutes 50 seconds
    On-Demand Vonoprazan for Non-Erosive Reflux Disease Symptoms: A New Option
    Philip Schoenfeld, MD, MSEd, MSc (Epi) and Christopher Velez, MD discuss “Randomised clinical trial: Efficacy and safety of on-demand vonoprazan versus placebo for non-erosive reflux disease,” by Fass R, Vaezi M, Sharma P, et al. Aliment Pharmacol Ther. 2023 Nov;58(10):1016-1027.
    20 November 2024, 4:00 pm
  • 15 minutes 40 seconds
    Suboptimal Adherence to Guidelines When Recommending Timing of Repeat Colonoscopy
    Philip Schoenfeld, MD, MSEd, MSc (Epi) and Margaret Zhou, MD, MS discuss “Colonoscopy quality measures and adherence to follow-up guidelines among endoscopists participating in a U.S. endoscopy registry,” by Shapiro JA, Holub JL, Dominitz JA R, et al. Gastrointest Endosc. 2024 Aug 5:S0016-5107(24)03404-7.
    20 November 2024, 4:00 pm
  • 14 minutes 56 seconds
    Reintroducing Foods After Completing Restrictive Low FODMAP Diet
    Philip Schoenfeld, MD, MSEd, MSc (Epi) and Jacqueline Gaulin discuss “Efficacy and Findings of a Blinded Randomized Reintroduction Phase for the Low FODMAP Diet in Irritable Bowel Syndrome,” by Van den Houte K, Colomier E, Routhiaux K, et al. Gastroenterology. 2024; 167: 333-42.
    20 November 2024, 4:00 pm
  • 25 minutes
    Quality Indicators for Colonoscopy: New Targets… But Will They Be Measured?
    Philip Schoenfeld, MD, MSEd, MSc (Epi) and Douglas K. Rex, MD discuss “Quality Indicators for Colonoscopy,” by Rex DK, Anderson JC, Butterly LF, et al. Am J Gastroenterol. 2024;119:1754-80.
    23 October 2024, 4:00 pm
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