Big Fat Negative: TTC, fertility, infertility and IVF

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Big Fat Negative is the podcast about IVF, infertility and the trials of TTC - aka trying for a baby. Co-hosted by journalists and friends Emma and Gabby, the show follows their stories on the not-so-simple journey to motherhood.

  • 37 minutes 56 seconds
    It's Louise Brown!!!!

    This week we are lucky enough to be joined by THE Louise Joy Brown, the first IVF baby. She talks about how her mum felt about going through IVF, her relationship with Bob Edwards, Patrick Steptoe and Jean Purdy, and why the science is now more important than ever.


    No Prof T again this week.


    To sign up to our Substack, you can go to https://bigfatnegative.substack.com/.


    Hosted on Acast. See acast.com/privacy for more information.

    3 December 2024, 12:01 am
  • 48 minutes 4 seconds
    Aisha Balesaria on childlessness not by choice

    This week we're talking to Aisha Balesaria, aka Mind Body Revival Coach, about childlessness not by choice. She discusses her chronic endometriosis and adenomyosis, and explains why having a strong idea of why you want a baby in the first place can be a great first step to deciding when to give up IVF treatment.


    You can find Aisha's book, We Are One in Eight, at Amazon here: https://www.amazon.co.uk/We-Are-One-Eight-infertility/dp/B092H9TMT8


    No Prof Tim this week!




    Hosted on Acast. See acast.com/privacy for more information.

    26 November 2024, 12:01 am
  • 34 minutes 58 seconds
    'Joy' creators Rachel Mason and Jack Thorne

    Surprise! We're here on a Friday to give you a little something extra: an interview with the screenwriters of the new Netflix movie Joy, which comes out today, starring Thomasin McKenzie, James Norton and Bill Nighy, about Jean Purdy, Robert Edwards and Patrick Steptoe, the creators of IVF.


    Rachel Mason and Jack Thorne tell us about how their own experiences of IVF informed the narrative of the movie, why it was important to centre the story on Purdy, and which of the stars is the most beautiful cryer.


    No Prof Tim this week - see you on Tuesday!


    Hosted on Acast. See acast.com/privacy for more information.

    22 November 2024, 12:01 am
  • 53 minutes 40 seconds
    Jessica Hepburn returns

    Last time we spoke to the author, adventurer and arts producer Jessica Hepburn was way back in 2019, when we talked about how she swam the English channel. Now she's back, to talk about her climb up Mount Everest - and why she listened to the entire back catalogue of Desert Island Discs while she did it.


    Meanwhile, Professor Tim is talking sperm cups: do they work?


    The link to the Guardian piece Emma read is here: https://www.theguardian.com/lifeandstyle/2024/nov/16/friendship-after-motherhood


    Swears throughout.


    Hosted on Acast. See acast.com/privacy for more information.

    19 November 2024, 12:01 am
  • 1 hour 11 minutes
    Maxine Peake and Hayley Jayne Standing

    Bafta-nominated actor and director Maxine Peake and the actor and writer Hayley Standing discuss their new short, Incompatible, which tells the story of a pregnant woman who is told her baby is incompatible with life, and their experiences of infertility.


    You can watch the film at https://vimeo.com/713200159, or see the trailer on its Instagram account: @incompatibleshortfilm.


    Meanwhile, Professor Tim addresses natural killer (NK) cells: should you be tested?


    Hosted on Acast. See acast.com/privacy for more information.

    12 November 2024, 12:01 am
  • 57 minutes 53 seconds
    Ariel Taylor on surrogacy

    In the second of our duo of episodes on surrogacy, Ariel Taylor, the founder of fertility and surrogacy organisation Carried With Love, talks about being a gestational carrier five times - and how it felt when she lost one of those pregnancies.


    Meanwhile, Prof T talks beta tests - why do some clinics do them and others don't?


    Scroll to 53:21 to hear Gabby's absolute banger. And if you want to check out Emma's interview with Jessica Valenti, you can read it here: https://www.thepersistent.com/us-presidential-election-abortion-voter-issues-jessica-valenti-interview/.


    Swears throughout.


    Hosted on Acast. See acast.com/privacy for more information.

    5 November 2024, 12:01 am
  • 40 minutes 51 seconds
    Ginanne Brownell on surrogacy

    Ginanne Brownell is a journalist whose jourrrrney took her to surrogacy via failed rounds of IVF and a very snazzy tattoo. Her new book, ‘Elusive Mommyhood: An Investigative Reporter's Personal Journey Into IVF and Surrogacy’ explores the history and politics of surrogacy in detail.


    And if you also want an Aku'aba tattoo, here it is.


    Meanwhile, Prof Tim talks about sex (baby): how often should you be Doing It?


    Hosted on Acast. See acast.com/privacy for more information.

    29 October 2024, 12:01 am
  • 1 hour 15 minutes
    Poet Harry Baker

    The poet Harry Baker went viral this summer for his poem Trying, a heart-rending description of the anguish of infertility (/ode to German linguistic precision).


    He joins us today to talk about his creative process and why putting into words what you are going through is so important.


    Meanwhile Prof (or is it Dr?) Tim talks about antibiotics: can you have them during pregnancy?


    Find Harry merch (and his books) at www.harrybaker.co.




    Hosted on Acast. See acast.com/privacy for more information.

    21 October 2024, 11:01 pm
  • 43 minutes 54 seconds
    Queer baby-making, with Marea Goodman

    If you make it past the unusually rambly intro, this episode we talk to Marea Goodman, a midwife who specialises in helping queer couples to conceive. We discuss at-home IUIs and the dangers of buying sperm online.


    Meanwhile, Professor Tim is talking about sex: should you do it after an embryo transfer?


    Swears, probably.


    Hosted on Acast. See acast.com/privacy for more information.

    14 October 2024, 7:01 pm
  • 55 minutes 11 seconds
    What it's like to have a miscarriage, with Poppy Child

    Poppy Child isn't our usual guest: she's a doula whose social media feeds are stuffed with advice on giving birth. But she has also experienced pregnancy loss, and that's what we're talking about today.


    TRIGGER WARNING: This episode covers pregnancy loss and miscarriage in detail. Please don't listen if you can't.


    Meanwhile, Professor Tim is talking about recurrent implantation failure: what tests should you do?



    Hosted on Acast. See acast.com/privacy for more information.

    7 October 2024, 11:01 pm
  • 54 minutes 36 seconds
    All about wombs, with Leah Hazard

    This week we're joined by Leah Hazard, the author of Womb: The Inside Story of Where We All Began. We talk about the things we don't know about the womb - like sperm crypts! - and current research which gives those suffering infertility just the tiniest glimmer of hope.


    Meanwhile, Professor Tim is talking about sugar - should we avoid it when we're TTC?


    Swears throughout.


    Hosted on Acast. See acast.com/privacy for more information.

    30 September 2024, 11:01 pm
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