In this episode of The Saving Lives Podcast, we delve into the intricate subject of advance directives in the intensive care setting. Titled "Deciphering the Complex World of Advance Directives in ICU Care: Challenges and Solutions," the episode explores the historical background, implementation challenges, and the impact of advance directives on patient care within ICUs. Let's highlight the practical difficulties healthcare professionals face in honoring patients' wishes and the varied effectiveness of advance directives across different regions. This episode aims to shed light on the importance of advance directives in ensuring patient autonomy and improving the quality of end-of-life care in critical settings.

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Citation: Baumann SM, Kruse NJ, Kliem PSC, Amacher SA, Hunziker S, Dittrich TD, Renetseder F, Grzonka P, Sutter R. Translation of patients' advance directives in intensive care units: are we there yet? J Intensive Care. 2023 Nov 15;11(1):53. doi: 10.1186/s40560-023-00705-z. PMID: 37968692; PMCID: PMC10648602.

In this episode of The Saving Lives Podcast, we explore the innovative MitraClip system, a less invasive treatment for mitral regurgitation. The discussion covers the device's evolution, its impact on patient outcomes, and the challenges and complications associated with its use.

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Citation: Schnitzler K, Hell M, Geyer M, Kreidel F, Münzel T, von Bardeleben RS. Complications Following MitraClip Implantation. Curr Cardiol Rep. 2021 Aug 13;23(9):131. doi: 10.1007/s11886-021-01553-9. PMID: 34387748; PMCID: PMC8363549.

In this episode of The Saving Lives Podcast, we delve into the compelling findings of a recent review on the adverse effects of physical restraint use in ICUs. We discuss the paradoxical nature of restraints, designed for patient safety but linked to significant complications, including skin injuries, delirium, PTSD, and more. Understanding the limitations of our current system, we explore how this research urges a shift towards more compassionate, patient-centered care and the critical need for alternative practices.

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Citation: Sebastian Berger, Pascale Grzonka, Simon A. Amacher, Sabina Hunziker, Anja I. Frei, Raoul Sutter, Adverse events related to physical restraint use in intensive care units: A review of the literature, Journal of Intensive Medicine, 2023,ISSN 2667-100X,

In this episode of The Saving Lives Podcast, we dive into a compelling study from the Annals of Intensive Care, exploring the prevalence and impact of hyperdynamic left ventricular systolic function in septic patients. Unpacking the findings, we discuss how this condition influences mortality rates and what it means for clinical practice in intensive care units.

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Citation: Sato R, Sanfilippo F, Hasegawa D, Prasitlumkum N, Duggal A, Dugar S. Prevalence and prognosis of hyperdynamic left ventricular systolic function in septic patients: a systematic review and meta-analysis. Ann Intensive Care. 2024 Feb 3;14(1):22. doi: 10.1186/s13613-024-01255-9. PMID: 38308701.

This episode delves into the 2024 update on corticosteroid guidelines for critically ill patients with sepsis, ARDS, and community-acquired pneumonia. We break down the recommendations, evidence, and clinical implications of this crucial guidance for healthcare providers.

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Citation: Chaudhuri D, Nei AM, Rochwerg B, Balk RA, Asehnoune K, Cadena RS, Carcillo JA, Correa R, Drover K, Esper AM, Gershengorn HB, Hammond NE, Jayaprakash N, Menon K, Nazer L, Pitre T, Qasim ZA, Russell JA, Santos AP, Sarwal A, Spencer-Segal J, Tilouche N, Annane D, Pastores SM. Executive Summary: Guidelines on Use of Corticosteroids in Critically Ill Patients With Sepsis, Acute Respiratory Distress Syndrome, and Community-Acquired Pneumonia Focused Update 2024. Crit Care Med. 2024 Jan 19. doi: 10.1097/CCM.0000000000006171. Epub ahead of print. PMID: 38240490.

In this episode, we delve into the groundbreaking study "Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction." We explore how Therapeutic Plasma Exchange (TPE) could revolutionize the treatment of sepsis, a condition notoriously difficult to manage. The episode breaks down the study's methods, results, and significant implications for future clinical practice, highlighting the urgent need for further research in this promising area.

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Citation: Kuklin V, Sovershaev M, Bjerner J, Keith P, Scott LK, Thomas OMT, Szpirt W, Rock G, Stegmayr B. Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis. Crit Care. 2024 Jan 4;28(1):12. doi: 10.1186/s13054-023-04795-x. PMID: 38178170; PMCID: PMC10768220.

In this episode of The Saving Lives Podcast, "Integrating Palliative Care in the ICU: Enhancing Quality of Life," host EddyJoe discusses the article 'Palliative Care in Intensive Care' from 'Intensive Care Medicine.' The episode examines how palliative care improves patient quality of life and reduces ICU stays, highlighting its role beyond end-of-life care. It emphasizes the need for training and changing perceptions among healthcare professionals. Essential for medical practitioners, this episode offers insights into incorporating palliative care into ICU practices for better patient outcomes.

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TrueLearn Link: ⁠⁠⁠⁠⁠⁠⁠⁠https://truelearn.referralrock.com/l/EDDYJOEMD25/⁠⁠⁠⁠⁠⁠⁠⁠ Discount code: EDDYJOEMD25

Citation: Neukirchen M, Metaxa V, Schaefer MS. Palliative care in intensive care. Intensive Care Med. 2023 Dec;49(12):1538-1540. doi: 10.1007/s00134-023-07260-z. Epub 2023 Nov 27. PMID: 38010381; PMCID: PMC10709230.

In this episode, we delve into the groundbreaking DAMIS trial, exploring the impact of sublingual microcirculation assessment on treatment decisions for ICU patients with shock. We discuss the methodology, findings, and implications of this extensive multicenter study, offering insights into how real-time microcirculatory data influences clinical outcomes in critical care. Join us for an in-depth analysis and expert opinions on this pivotal topic in intensive care medicine.

Show Notes: https://eddyjoemd.com/damis-trial-microcirculation/

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Citation: Bruno RR, Wollborn J, Fengler K, Flick M, Wunder C, Allgäuer S, Thiele H, Schemmelmann M, Hornemann J, Moecke HME, Demirtas F, Palici L, Franz M, Saugel B, Kattan E, De Backer D, Bakker J, Hernandez G, Kelm M, Jung C. Direct assessment of microcirculation in shock: a randomized-controlled multicenter study. Intensive Care Med. 2023 Jun;49(6):645-655. doi: 10.1007/s00134-023-07098-5. Epub 2023 Jun 6. Erratum in: Intensive Care Med. 2023 Oct;49(10):1279. PMID: 37278760; PMCID: PMC10242221.

This Podcast was edited using Descript: ⁠⁠⁠⁠⁠https://www.descript.com?lmref=BGOxjQ⁠⁠⁠⁠

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Show Notes: eddyjoemd.com/asymptomatic-catheter-related-thrombosis/

Explore the often-overlooked issue of asymptomatic catheter-related thrombosis (CRT) in ICU patients on The Saving Lives Podcast. This episode delves into a revealing study published in the Annals of Intensive Care, uncovering the incidence, risk factors, and implications of asymptomatic CRT. Join us for a thought-provoking discussion that challenges traditional beliefs and sheds light on crucial aspects of catheter management in critical care.

TrueLearn Link: ⁠⁠⁠⁠⁠⁠⁠https://truelearn.referralrock.com/l/EDDYJOEMD25/⁠⁠⁠⁠⁠⁠⁠ Discount code: EDDYJOEMD25

This Podcast was edited using Descript: ⁠⁠⁠⁠https://www.descript.com?lmref=BGOxjQ⁠⁠⁠⁠

Citation: Abbruzzese C, Guzzardella A, Consonni D, Turconi G, Bonetti C, Brioni M, Panigada M, Grasselli G. Incidence of asymptomatic catheter-related thrombosis in intensive care unit patients: a prospective cohort study. Ann Intensive Care. 2023 Oct 19;13(1):106. doi: 10.1186/s13613-023-01206-w. PMID: 37858003; PMCID: PMC10587047. Link to Article

This episode delves into the pivotal EuRIDICE randomized clinical trial published in Critical Care in 2023. This episode provides an in-depth analysis of the trial's findings on using haloperidol in managing delirium among critically ill adults in the ICU. We'll explore the implications of these results for clinicians and the broader healthcare community, discussing whether haloperidol truly impacts the duration of delirium and coma in ICU patients. This discussion is essential for medical professionals, from students to board-certified physicians, seeking to stay informed on the latest in critical care medicine. Tune in to gain valuable insights and broaden your understanding of ICU delirium management.

This Podcast was Editing Using Descript: ⁠⁠https://www.descript.com?lmref=BGOxjQ⁠⁠

TrueLearn Link: ⁠⁠⁠⁠⁠https://truelearn.referralrock.com/l/EDDYJOEMD25/⁠⁠⁠⁠⁠ Discount code: EDDYJOEMD25

Show Notes: ⁠https://eddyjoemd.com/book/⁠ 

This Podcast was Editing Using Descript: ⁠https://www.descript.com?lmref=BGOxjQ⁠

TrueLearn Link: ⁠⁠⁠⁠https://truelearn.referralrock.com/l/EDDYJOEMD25/⁠⁠⁠⁠ Discount code: EDDYJOEMD25