The Empowering Neurologist Podcast

David Perlmutter MD

The Empowering Neurologist is an interview series with some of the most exciting thought leaders in the field of health and wellness.

  • 1 hour 3 minutes
    Exciting Developments in the Treatment of Peripheral Neuropathy - with Dr. Fernyhough & Dr. Calcutt | EP 179

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    As many of you are aware, much of our information that we present deals with problems of the brain and spinal cord. These have been described as being parts of the central nervous system. However, there is another part of the nervous system called the peripheral nervous system that is basically made up of the peripheral nerves.


    Peripheral neuropathy is a term that describes an abnormality with peripheral nerves. This can cause loss of sensation, pain, or even loss of autonomic function. Here in America some 20 million people suffer from peripheral neuropathy. In fact more than half of the people with diabetes will develop prayerful neuropathy at some point in their lifetimes. We are at increased risk for peripheral neuropathy not only as a consequence of diabetes but also as we age. Pray for neuropathy can be caused by chemotherapy and fully 1/4 of all peripheral neuropathy patients do not have an identifiable cost.


    There aren't really any FDA approved treatments to actually treat purple neuropathy in terms of the underlying cause of the nerve damage. While we do have drugs that treat, pain for example, again we need to find a way of treating the fire, not just focusing on the smoke. Having said that, there is an exciting new development in this field using drugs that are already available and are called muscarinic antagonists. Basically, they block the transmission of acetylcholine.


    In today's podcast, we are going to explore deeply, the mechanisms whereby this approach, using these muscarinic antagonists seems to be incredibly effective in growing new nerve fibers as well as increasing metabolism in the nerve itself leading to improvement ultimately in the manifestation of peripheral neuropathy.


    ===

    0:00 Intro

    5:35 The Scope of the Problem

    8:09 Diabetic Neuropathy 

    11:49 Neuropathy Following Chemotherapy 

    14:21 Viral Infections: HIV Treatment & Covid

    16:56 Why Mitochondria are Essential in This

    19:44 Pharmaceutical Study of Neuropathy 

    24:57 Aldose reductase inhibitor

    29:31 Why This Approach is Different

    37:44 How Antimuscarinics Work

    48:10 Metrics for Getting FDA Approval

    58:42 Funding the Research

    1:01:53 Conclusion 

    ====

    Nigel A. Calcutt, Ph.D. ook both his B.Sc. in Zoology and Ph.D. Physiology and Pharmacology at Nottingham University, England. Dr. Calcutt first began studying nerve damage caused by diabetes as an undergraduate, with a largely unsuccessful but nevertheless entertaining and informative attempt to generate diabetic chickens in the laboratory of the esteemed ornithologist Professor David Tomlinson. Undeterred by the pitiful paucity of pre-diabetic poultry, he has continued to investigate mechanisms of diabetic neuropathy and neuropathic pain throughout his academic career, with a particular interest in translational studies. Dr. Calcutt is also a co-founder of the biotechnology company WinSanTor Inc. and the non-profit organization Diabetes Research Connection. Paul Fernyhough PhD received his PhD in biochemistry from the department of Biochemistry at University of Sheffield. He then carried out postdoctoral research at Colorado State University, Kings College London and as a Wellcome Trust Postdoctoral Fellow at St Bartholomew’s Medical College. Dr. Fernyhough’s research interest is in the cell biology underlying neurodegenerative disorders of the peripheral nervous system with a focus on the impact of diabetes. A biotech start-up, WinSanTor Inc, has been established and is directing phase 2 clinical trials in diabetic neuropathy and chemotherapy-induced peripheral neuropathy. ___________________________ Instagram: https://www.instagram.com/davidperlmutter/ Website: https://www.drperlmutter.com/ Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1

    22 April 2024, 5:00 pm
  • 55 minutes 1 second
    Inside the Study That Reveals Promise for Treating Multiple Sclerosis with Stem Cells - with Dr. Stefano Pluchino | EP 178

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    In a groundbreaking development, an international team of researchers has unveiled a remarkable advancement in the fight against progressive multiple sclerosis (MS). Their study, led by scientists from the University of Cambridge, the University of Milan Bicocca, and Hospital Casa Sollievo della Sofferenza in Italy, demonstrates the safety, tolerance, and long-lasting effectiveness of injecting a specific type of stem cell directly into the brains of patients living with progressive MS. This breakthrough paves the way for the development of advanced cell therapy treatments for this debilitating disease that affects over 2 million people worldwide.


    Multiple sclerosis is a complex autoimmune disease that targets the central nervous system, leading to severe disruption in the transmission of nerve signals. While there are treatments available to alleviate some of the symptoms and reduce the frequency of relapses, many patients still progress into a secondary phase of the disease, which steadily worsens over time, causing severe disability. This secondary progressive phase has long been a significant challenge in the treatment of MS.


    In progressive forms of MS, a type of immune cell known as macrophages, specifically microglial cells, plays a crucial role in attacking and damaging the central nervous system. This relentless assault leads to chronic inflammation and extensive nerve cell damage. Recent advances in stem cell therapies have raised hope that they could help mitigate this damage by replacing damaged cells with healthy ones.


    Before the current study, the University of Cambridge team had already demonstrated in mouse models that reprogrammed skin cells into brain stem cells, transplanted into the central nervous system, could reduce inflammation and potentially aid in repairing MS-related damage.


    This groundbreaking study marks a significant step forward in the pursuit of effective treatments for secondary progressive MS. Although the study is relatively small and may have confounding effects from immunosuppressant drugs, its safety and long-lasting effects over the 12-month trial period have paved the way for further clinical trials. The research team's cautious optimism fuels hope for the development of cell therapy as a potential solution for this debilitating condition. This exciting progress holds the promise of a brighter future for the millions of people living with progressive MS, offering renewed hope for a more effective treatment approach.


    Our interview today is with the lead researcher involved in this study at the University of Cambridge, Stefano Pluchino, MD, PhD.


    ====

    0:00 Intro

    2:46 Why Stem Cell Therapy Works

    5:10 Studying Stem Cells on the Brain

    9:15 MS Patients Studied in This Trial 

    13:43 What the Results Mean for the Public

    17:40 The Specifics of the Study

    26:18 Rigorous Testing that Sets this Trail Apart

    28:25 Findings: Feasibility, Safety, and Biomarkers 

    34:32 Looking at the Results over 12 months

    40:11 Correlation of Metabolic Health and MS

    44:55 What Exosomes Reveal About Disease

    49:01 Senolytic Therapy & Neurodegenerative Diseases

    53:36 Conclusion 

    ====


    Stefano Pluchino received his MD and PhD degrees at the University of Siena, Italy,

    and additional training at Cambridge University, UK. He is currently Professor of

    Regenerative Neuroimmunology (2021) and Honorary Consultant in Neurology, within

    the Department of Clinical Neurosciences at Cambridge University.


    Twitter: @Pluchinolab

    Research: https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(23)00393-4


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    8 April 2024, 5:00 pm
  • 51 minutes 49 seconds
    A Solution to the Alarming Drop in Testosterone Levels Worldwide: The Promise of TRT - Dr. Tracy Gapin | EP 177

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    In this episode of The Empowering Neurologist, we're diving into two topics that are gaining significant attention in the worlds of men's health and weight loss: the importance of testosterone replacement therapy and the emerging role of GLP-1 agonists in weight loss as well as in diabetes treatment. Joining us is an esteemed expert in this field, Dr. Tracy Gapin, a renowned urologist and men's health specialist.

    Why is this topic so crucial? Testosterone, often hailed as the cornerstone of male vitality, plays a central role in various aspects of men's health. It's not just about physical strength or libido; testosterone impacts mood, energy levels, bone density, muscle mass, cognitive function, and overall well-being. However, as men age, testosterone levels naturally decline, leading to a condition known as hypogonadism or low testosterone. This decline can have profound effects on a man's health and quality of life.

    Dr. Gapin, with his extensive experience and research in the field, sheds light on how testosterone replacement therapy can be a game-changer for men experiencing the effects of low testosterone. He delves into the nuances of identifying candidates for this therapy, the benefits, and the misconceptions surrounding it. His insights are particularly valuable in a time when discussions about men's hormonal health are often overshadowed or misunderstood. Further, as he explains, age-matched testosterone levels in men have plummeted over the past several decades, and we discuss why.

    In addition, Dr. Gapin takes us through the exciting world of GLP-1 agonists, a class of drugs initially developed for diabetes management but now having a major impact in the weight loss arena. Obesity is a mounting concern globally, and its impact on men's health is undeniable. With cardiovascular disease, diabetes, and a host of other conditions linked to obesity, finding effective weight management solutions is paramount. Dr. Gapin explains how GLP-1 agonists work, their benefits, their potential risks, and their role in revolutionizing weight loss treatments.

    This episode is not just for those directly experiencing these issues but also for anyone interested in the broader conversation about men's health. Whether you're a healthcare professional, someone exploring options for personal health improvement, or simply curious about the latest in medical advancements, Dr. Gapin's insights offer valuable knowledge and perspective.


    ====

    0:00 Intro

    3:04 The Issues of Low Testosterone

    7:07 Why Testosterone Levels are Falling

    10:00 What Indicates Low Testosterone

    15:00 The Holistic Approach to This

    17:28 Why Testosterone Replacement Therapy May Be Essential

    19:53 Addressing Potential Risks

    28:20 How TRT Works & What to Expect

    35:49 Looking at Estrogen and Progesterone 

    37:23 LDL Medication and Low Testosterone

    39:55 Addressing Thyroid Functionality

    40:56 Honest Thoughts on Ozempic

    50:28 Conclusion

    ====


    Tracy Gapin, MD, is a board-certified urologist, men’s health and performance expert. and founder of the Gapin Institute, a global leader in high performance medicine. He has over 20 years of experience focused on providing executives, entrepreneurs and athletes a personalized path to optimizing their health so they can have exceptional energy, laser-focused mind and a better body.


    Text HEALTH to 26786 to receive an electronic copy of the High Performance Health Handbook for Men


    ___________________________

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    25 March 2024, 7:09 pm
  • 46 minutes 7 seconds
    The Autoimmune Cure: Healing the Trauma & Triggers that Turn Your Body Against You - Dr. Sara Gottfried | EP 176

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    Hello everyone. I am delighted to let you all know about this episode of The Empowering Neurologist. We discuss fundamentally important new book, The Autoimmune Cure, by one of my dearest friends on the planet, New York Times bestselling author, Dr. Sara Gottfried.

    In this interview, Dr. Gottfried enlightens us as to what is really underlying the vast array of autoimmune conditions. Yes, we do get into the weeds, but the information she provides is not just fascinating, but fully empowering as well. Prepare to be enlightened as she sheds light on how trauma can intricately rewire our bodies, ultimately becoming the catalyst for autoimmune diseases. With a prevalence that's skyrocketing globally, autoimmune conditions affect millions, yet the root cause often remains elusive.

    Conventional medicine's approach often falls short in effectively diagnosing and treating autoimmune disorders. Many individuals grapple with baffling symptoms ranging from fatigue to brain fog, from aches and pains to anxiety, unaware that their immune system is the culprit behind their distress. Drawing from her wealth of experience in precision medicine, Dr. Gottfried has uncovered a compelling correlation between autoimmune disease and a history of trauma, a revelation that's shaping the future of autoimmune care.

    But here's the exciting and empowering part—there's hope. Dr. Gottfried's revolutionary program outlined in he Autoimmune Cure offers a beacon of hope for those navigating the treacherous waters of autoimmune ailments. By addressing the root cause head-on and providing a comprehensive roadmap to reset the immune system, this program empowers individuals to reclaim their health and vitality.

    So,  join us as we embark on a transformative journey towards autoimmune liberation. Whether you're grappling with autoimmune symptoms yourself or seeking to deepen your understanding of immune health, this podcast episode promises to be a beacon of insight and inspiration.


    ====

    0:00 Intro

    2:15 We’re Looking at Autoimmune Wrong

    8:04 Using Psychedelics for Healing Trauma 

    12:58 Long Covid’s Impact on the Body

    16:11 Thyroid Disruption

    19:03 The Microbiome’s Impact on Immune Function

    24:55 Symptoms Checklist & MS

    30:26 Why Women have a Higher Risk 

    37:19 Praise for Dr. Gottfried’s World

    44:29 Conclusion

    ====


    Sara Szal Gottfried MD is a physician, researcher, author, and educator. She graduated from Harvard Medical School and MIT, and completed residency at UCSF, but is more likely to prescribe a CGM and personalized nutrition plan than the latest pharmaceutical. Dr. Gottfried is a global keynote speaker and the author of four New York Times bestselling books about hormones, nutrition, and health. Her latest book is called THE AUTOIMMUNE CURE (March 2024). She is Clinical Assistant Professor in Dept. of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University, and Director of Precision Medicine at the Marcus Institute of Integrative Health. She takes care of executives and professional athletes. Her focus is at the interface of mental and physical health, N-of-1 trial design, personalized molecular profiling, use of wearables, and how to leverage these tools to improve health outcomes. Learn more at SaraGottfriedMD.com


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    11 March 2024, 5:00 pm
  • 59 minutes 43 seconds
    Replacing Fructose with Allulose: Exploring the Science Artificial Sweeteners - Dr. Johnson | EP 175

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    With so much discussion these days centered on metabolic health and issues like overweight, obesity, diabetes, and the downstream consequences of these health challenges, I think it's important to spend some time looking at what may be one of the pivotal  causes of metabolic disturbances, the consumption of fructose sugar.


    As such, I reached out to Dr. Richard Johnson, a world’s authority on the role of fructose in human metabolism, to share with us his latest thoughts not only related to fructose, but also including the various types of sweeteners that are available and have become very popular. 


    This discussion will take us into the world of GLP-1, a receptor that is stimulated by drugs like Ozempic. And no doubt, that is an area of discussion that is interesting for so many people.


    We begin our discussion however with Dr. Johnson describing his recent trip to Dubai where he attended the COP 28 climate conference which, interestingly, includes his insights related to the threats posed by climate change on human metabolism.


    Let me tell you a little bit more about Dr. Richard Johnson.He was formerly the chief of the Renal Division and Hypertension at the University of Colorado for nine years. He’s a physician, trained in internal medicine, infectious disease, and nephrology. Dr. Johnson is a widely cited NIH-funded scientist who has lectured in over 40 countries and has authored three books, The Sugar Fix, The Fat Switch, and the new Nature Wants Us to Be Fat. Rick has a special interest in the role of sugar and especially fructose and its byproduct uric acid in driving metabolic and kidney disorders. And most recently he has been exploring the biological properties of a unique sugar, allulose, a topic we discuss in great depth.


    ====

    0:00 Intro 

    1:56 Climate Change and Rising Health Concerns 

    12:53 Correlation of Uric Acid and Impulsivity

    20:50 The Mechanics of Obesity as a Low Energy State

    26:12 How Our Biology Supports Weight Gain

    28:38 Impact of Sugar and Carbs on the Body

    31:50 Should you avoid fruit?

    33:09 What We should Be Doing

    35:03 The World of Low Calorie Sugars

    37:55 Disadvantages of Artificial Sweeteners 

    41:32 Allulose: The Next Best Thing? 

    54:19 How CGMs Will Change Your Perspective

    55:10 The Role of Quercetin on Mitophagy 

    58:20 Conclusion

    ====


    Dr. Johnson has performed medical research since the early 1980s and has been funded by the NIH since 1987. Most of  his research has focused on the pathogenesis of kidney diseases, but during the last 12 years his studies have also included studies of the pathogenesis of primary hypertension, insulin resistance and diabetes, diabetic nephropathy, and obesity. Much of his work has involved a combination of cell culture and animal models with a strong translational component, but he has also been involved in a number of clinical trials and epidemiology-based studies.

    ___________________________

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    26 February 2024, 6:00 pm
  • 51 minutes 9 seconds
    Can This Wearable Device Reduce Stress? A Deep Dive into the Apollo | Dr. Dave Rabin - EP 174

    Interested in an Apollo device? Click the following link and use code PERLMUTTER for a 15% OFF discount. https://apolloneuroscience.pxf.io/c/4460811/1861953/12331


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    Clearly, we've communicated a lot of information indicating that it's really fundamentally important for our health and ability to resist disease that we gain control over things like anxiety, lack of restorative sleep, lack of exercise, and certainly make other good choices like eating appropriately as well. These are powerful modulators of our metabolic health I have wide ranging implication not just as it relates to the brain, but our entire physiology. 


    How exciting is that we live in the day and age of wearable devices. And, importantly, we now see the development of a wearable device that specifically allows us in a non pharmaceutical way to deal with anxiety, help us through the days it relates to our decision making ability, and even help us in the night as a relates to sleep, and it’s called Apollo. I thought it would be a great idea to interview the creator of this device, Dr. David Ravin.


    Dr. David Rabin, MD, PhD, a board-certified psychiatrist and neuroscientist, is the co-founder & chief medical officer at Apollo Neuroscience, the first scientifically-validated wearable system to improve heart rate variability, focus, relaxation, and access to meditative states by delivering gentle layered vibrations to the skin. In addition to his clinical psychiatry practice, Dr. Rabin is also the co-founder & executive director of The Board of Medicine, and a psychedelic clinical researcher currently evaluating the mechanism  of psychedelic-assisted psychotherapy in treatment-resistant mental illnesses.


    This is a very interesting podcast about a very interesting and clearly beneficial wearable device. I have found that using this device my heart rate variability has gone up dramatically, which is a good thing, and something I have been trying to accomplish for quite some time. This has huge implications for health. I hope you enjoy this information.


    ====

    0:00 Intro

    3:09 Where It All Began - Searching for Stress Solutions

    7:18 MDMA Therapy for PTSD

    9:52 Why the Pushback on Psychedelic Therapy? 

    12:20 New Wearable Tech that Simulates MDMA Benefits

    19:56 Creating the Apollo 

    24:53 Key Metric: Heart Rate Variability 

    29:10 Dr. Perlmutter’s Success Story with the Apollo

    34:32 Perceived vs Real Threat in Anxiety

    36:53 Other Success Stories with Apollo

    42:51 Solving the Problems of Sleep

    50:04 Conclusion

    ====


    Dr. David Rabin, MD, PhD, a board-certified psychiatrist and neuroscientist, is the co-founder & chief medical officer at Apollo Neuroscience, the first scientifically-validated wearable system to improve heart rate variability, focus, relaxation, and access to meditative states by delivering gentle layered vibrations to the skin. In addition to his clinical psychiatry practice, Dr. Rabin is also the co-founder & executive director of The Board of Medicine, and a psychedelic clinical researcher currently evaluating the mechanism  of psychedelic-assisted psychotherapy in treatment-resistant mental illnesses. 


    Socials:

    Drdave.io

    Apolloneuro.com

    Boardofmedicine.org

    Twitter: @daverabin


    Instagram: @drdavidrabin


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    12 February 2024, 6:00 pm
  • 1 hour 2 minutes
    Your Brain on Art: The Science of Creativity and Neurological Health | Ivy Ross & Susan Magsamen - EP 173

    To save 15% off an Apollo device, click THIS LINK and use code PERLMUTTER at checkout.


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    One area that we spend a lot of time exploring focuses on the role of lifestyle choices as they relate to brain, health, functionality, and resistance to disease. I have to admit, over the years I have perhaps somewhat neglected a very important tool that offers up incredible utility as a relates to doing good

    things for the brain, and that is art. With that in mind, I felt it would be a great idea to interview the authors of an exciting new book that explores this very topic entitled, Your Brain on Art by Susan Magsamen and Ivy Ross.

    Your Brain on Art explores the vital role of arts in our lives, beyond mere entertainment. The book reveals a cultural evolution where arts emerge as powerful, accessible solutions for overall well-being. The authors present robust research highlighting the health benefits of art engagement. They illustrate how just 45 minutes of an art activity can significantly reduce stress hormones regardless of skill level, and regular artistic engagement could potentially extend life expectancy by a decade. The book delves into how music fosters cognitive abilities, the therapeutic effects of sound vibrations, the innovative use of virtual reality in therapy, and how interactive art experiences enhance memory and sensory engagement. It also discusses how art is being integrated into medical prescriptions for various health issues like loneliness and dementia.


    Your Brain on Art serves as a gateway to understanding the intersection of arts, aesthetics, and wellness. It includes discussions with renowned figures like David Byrne, Renée Fleming, and E. O. Wilson, offering a comprehensive view of neuroaesthetics. This guide combines cutting-edge research, multidisciplinary expert insights, and inspirational stories, showcasing how arts significantly improve life quality.


    ====

    0:00 Intro 

    3:07 How Susan & Ivy Began Studying Art

    9:20 Why Art is Necessary for Humanity 

    14:22 Your Brain on Art

    18:50 How Observing Art Helps Us 

    20:34 Reducing Amygdala Actions

    22:16 The Healing Power of Sound and Vibration 

    25:18 The Role of Aesthetics & Awe of Nature 

    32:06 Poetry: the Oldest Art Form 

    34:48 Treating Mental Illness with Art

    40:06 Why Talent Doesn’t Matter

    44:14 Creative Flow & Mindfulness

    45:34 Theatre & Connecting to Our Emotions

    51:04 Psychedelics for Healing

    57:30 The Art of Food

    1:00:51 Conclusion

    ====


    Susan Magsamen is the founder and executive director of the International Arts + Mind Lab (IAM Lab), Center for Applied Neuroaesthetics, a pioneering neuroaesthetics initiative from the Pedersen Brain Science Institute at Johns Hopkins University School of Medicine. Susan’s work focuses on how the arts and aesthetic experiences measurably change the brain, body and behavior and how this knowledge can be translated to inform health, wellbeing and learning programs in medicine, public health and education. 

     Magsamen is also the co-author of the New York Times Bestseller, Your Brain on Art: How the Arts Transform Us written for the general public. 


    ===


    Ivy Ross is the Vice President of Design for the Hardware organization at Google. Over the past six years, she and her team have launched 50+ products winning over 240 global design awards. This collection of hardware established a new Google design aesthetic that is tactile, colorful, and bold.

    Most recently, Ivy co-authored with SusanMagsamen Your Brain on Art: How the ArtsTransform Us.


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    29 January 2024, 6:00 pm
  • 52 minutes 5 seconds
    Healing Loneliness Through Creativity, Awe, and Connection - with Dr. Nobel | EP 172

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    Loneliness is pervasive in our modern world. The sense of isolation and lack of connection, clearly made worse by the COVID pandemic, is associated with a wide scope of health issues and even mortality. So what do we do?

     

    Some important steps are presented in our podcast, an interview with the author of Project Unlonely - Healing Our Crisis of Disconnection, Dr. Jeremy Nobel.

     

    Jeremy Nobel, M.D., MPH, is a primary-care physician, public health practitioner, and award-winning poet with faculty appointments at the Harvard T.H. Chan School of Public Health and the Harvard Medical School. He is the founder and president of the Foundation for Art & Healing (www.ArtandHealing.org), whose signature initiative, Project UnLonely, addressing the personal and public health challenges of loneliness and social isolation, has gained national visibility.

     

    This is an important topic, not just for the elderly, living alone, but for all of us. For it is clear that any of us can feel lonely and disconnected, even in the midst of our busy lives.

     

    ====

    TIMESTAMPS:

    0:00 Intro

    2:10 Our Epidemic of Loneliness

    6:11 Leveraging the Creative Arts for Healing

    12:21 Evaluating Loneliness in Studies

    16:31 How Loneliness Equates to Heightened Disease Risk

    19:43 The Loneliness Spiral

    21:56 Inflammation

    24:38 How World Events Impact Well-Being

    26:45 What You Can Do: Art as a Medium for Healing

    31:05 How Psychedelics Overlap with Creativity

    35:44 Cultural Norms Impact Loneliness

    38:31 The Biggest Challenge for Moving Forward

    40:57 The Potential of Awe and Nature-Connection

    44:24 Correlation Between Loneliness and FMRI Imaging

    50:00 Conclusion

    ====

     

    JEREMY NOBEL, M.D., MPH, is a primary-care physician, public health practitioner, and award-winning poet with faculty appointments at the Harvard T.H. Chan School of Public Health and the Harvard Medical School. He is the founder and president of the Foundation for Art & Healing (www.ArtandHealing.org), whose signature initiative, Project UnLonely, addressing the personal and public health challenges of loneliness and social isolation, has gained national visibility.

     

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    15 January 2024, 6:00 pm
  • 46 minutes 7 seconds
    Plastic Surgeon: The Secret to Holistic Anti-Aging and Youthful Skin - with Dr. Anthony Youn | EP 171

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    Who knew? The same mechanisms that are involved in brain degeneration, cardiovascular disease, and virtually any other chronic degenerative decline that we experience in our bodies is also at play on our bodies, meaning affecting our skin. Yes, free radical mediated stress and inflammation are the pillars of what causes good skin to go bad. So, with that in mind I felt it would be terrific to interview a leader in holistic approaches to skin care and plastic surgery, Dr. Anthony Youn. Let me tell you more about him.

     

    Known as America's Holistic Plastic Surgeon®, Anthony Youn, M.D. F.A.C.S is a nationally-recognized, board-certified plastic surgeon. Recognized as a leader in his field, he is the author of the best-selling books “The Age Fix," "In Stitches," and “Playing God.” His public television special, The Age Fix with Dr. Anthony Youn, has been viewed by millions.  Dr. Youn also hosts the popular podcast The Holistic Plastic Surgery Show.  He is the most followed plastic surgeon on social media, with over 4.5 million subscribers on his YouTube Channel and 8 million followers on TikTok. His new book, “Younger for Life” is a complete holistic guide to turning back the clock using the process of Autojuvenation®.

     

    I learned an awful lot today on this podcast and hope you do too.

     

     

    ====

    TIMESTAMPS:

    0:00 Intro

    3:00 Dr. Youn’s Wake-up Call From Plastic Surgery

    7:05 5 Accelerates for Skin Aging

    10:44 What Causes Loss of Collagen

    14:59 Healing the Skin Microbiome

    17:38 Challenging the Dogma of Plant-Based Collagen

    20:24 How to Supplement Collagen

    21:29 Skin Cancer, Sun Exposure & Healthy Sunscreens

    30:18 How Our Food Choices Cause Skin Inflammation

    34:39 Autophagy: Small Steps that Lead to Big Changes

    41:03 Botox & Fillers: What You Should Know

    43:46 Conclusion

    ====

     

    Known as America's Holistic Plastic Surgeon®, Anthony Youn, M.D. F.A.C.S is a nationally-recognized, board-certified plastic surgeon. Recognized as a leader in his field, he is the author of the best-selling books “The Age Fix," "In Stitches," and “Playing God.” His public television special, The Age Fix with Dr. Anthony Youn, has been viewed by millions.  Dr. Youn also hosts the popular podcast The Holistic Plastic Surgery Show.  He is the most followed plastic surgeon on social media, with over 4.5 million subscribers on his YouTube Channel and 8 million followers on TikTok. His new book, “Younger for Life” is a complete holistic guide to turning back the clock using the process of Autojuvenation®.

     

    ___________________________

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    Website: https://www.drperlmutter.com/

     

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    2 January 2024, 6:00 pm
  • 46 minutes 34 seconds
    Calm your Mind with Food: A Revolutionary Approach to Anxiety - with Dr. Uma Naidoo | EP 170

    🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱

     

    Get a special sneak peek of Calm Your Mind with Food here if you join Dr. Uma’s weekly email list: https://umanaidoomd.com/pages/calmyourmindwithfoodsneakpeek

     

    Want even more? Get a special introduction to Nutritional Psychiatry for reducing anxiety and depression symptoms in a special 6-lesson mini-course from Dr. Uma, bundled with a copy of her book: https://umanaidoomd.com/products/calm-your-mind-with-food-anti-anxiety-course-book-bundle

     

    ====

     

    Anxiety issues are certainly pervasive, and becoming much more common in our very stressful world. Generally, to go to therapy for dealing with anxiety seems to be pharmacotherapy, in other words, drugs. And while drugs may take the edge off and prove to be effective, it's good to know there are other ideas that are being considered. One important inroad into treating anxiety focuses on dietary change. We know that the consumption of the typical standard American diet is fraught with issues including posing a threat to metabolism by virtue of our consumption of large amount of ultra process foods which actually make up between 52 to 54% of of the calories consumed every day in American adults. This is a diet that has been associated with a dramatic increase risk for metabolic issues, cardiovascular disease, and even threatens the brain. As we will learn today, our consumption of these highly refined foods plays a role in creating anxiety as well.

     

    Our guest today is Dr. Uma Naidoo, and we will be discussing her new book, Calm Your Mind with Food - A Revolutionary Guide to Controlling Your Anxiety.

     

    Please enjoy the podcast.

     

    ====

    0:00 Intro

    3:42 The Rising Problem of Anxiety

    6:37 Nutritional Psychiatry: Eating for Mental Health

    9:51 Foods that Cause Anxiety

    13:20 The Process of Healing Through Food

    16:50 How We Can Gauge Progress

    19:40 Helpful Lab Studies & Food Allergies

    23:22 The Benefits of Supplements & Which to Take

    28:04 Metabolic Issues & Anxiety

    30:23 Bringing Medical Specialities Together

    34:16 Starting Small and Regaining Control

    37:35 Commonly Used Drugs that Impact Mood Disorders

    39:33 Leptin Levels and Anxiety

    42:13 The Future of Nutritional Psychiatry

    45:20 Conclusion

    ====

     

    Michelin-starred chef David Bouley described Dr. Uma Naidoo as the world’s first “triple threat” in the food and medicine space: a Harvard-trained psychiatrist, professional chef graduating with her culinary schools’ most coveted award, and a trained Nutrition Specialist. Her nexus of interests have found their niche in Nutritional Psychiatry.

     

    Dr. Naidoo founded and directs the first hospital-based Nutritional Psychiatry Service in the United States. She is the Director of Nutritional and Lifestyle Psychiatry at Massachusetts General Hospital (MGH) & Director of Nutritional Psychiatry at MGH Academy while serving on the faculty at Harvard Medical School.

     

    She is considered Harvard’s Mood Food Expert and has been featured in the Wall Street Journal, Goop, Live with Kelly & Ryan, and more. Dr. Naidoo is also the national bestselling author of This Is Your Brain on Food: https://umanaidoomd.com/collections/this-is-your-brain-on-food, and the upcoming title that we will discuss today, Calm Your Mind With Food https://umanaidoomd.com/collections/calm-your-mind-with-food

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    19 December 2023, 5:14 pm
  • 52 minutes 44 seconds
    A Sugar Substitute That’s Good For You? The Science Behind Allulose - with Dr. Bikman | EP 169

    Get up to 53% off the P600 cookware and a FREE set of silicone utensils: https://chefsfoundry.com/DrPerlmutter

     

    🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: https://www.drperlmutter.com/ ✉️🌱

     

    Allulose as a sugar is getting a lot of well deserved attention. We are seeing some pretty remarkable science with respect to allulose as it relates to metabolic health and specifically, weight loss. I felt, as such, that it would be a good idea to interview Dr. Benjamin Bikman on the Empowering Neurologist program today. Let me tell you more about Dr. Bikman.

     

    Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore in metabolic disorders.  Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the role of elevated insulin and nutrient metabolism in regulating obesity, diabetes, and dementia.

     

    In our time together, we discuss the important science of allulose as it relates to fat distribution in the body, insulin resistance, heart disease, fatty liver disease, cognitive decline, and even how allulose is able to lower uric acid, an area that I'm certainly interested in.

     

    I hope you enjoy this fascinating interview with Dr. Benjamin Bikman.

     

    ====

    TIMESTAMPS:

    0:00 Intro

    2:08 The Study of Metabolism

    4:53 Dr. Bikman's Insulin Research

    7:08 Why People's Bodys Aren’t Able to Use Insulin Correctly

    10:12 What Causes Spikes in Insulin Levels

    14:59 Problem with Annual Fasting Blood Sugar Test

    17:24 Merits of a Continuous Glucose Monitor

    19:53 New Sugar Replacement: Allulose

    30:43 Bringing Down Uric Acid with Allulose

    33:17 Allulose & Insulin Resistance

    35:52 Reducing Fatty-Liver Disease Risk

    38:48 Protecting Mitochondria Against Cardiovascular Disease

    42:00 Cognitive Decline & Allulose

    44:42 Preventing Alzheimers

    51:28 Conclusion

    ====

     

    Benjamin Bikman earned his Ph.D. in Bioenergetics and was a postdoctoral

    fellow with the Duke-National University of Singapore in metabolic disorders.

    Currently, his professional focus as a scientist and professor (Brigham Young

    University) is to better understand the role of elevated insulin and nutrient

    metabolism in regulating obesity, diabetes, and dementia.

     

    Dr. Bikman is the author of the book: Why We Get Sick

    Dr. Bikman’s education platform: https://www.insuliniq.com/

     

     

    ___________________________

    Instagram: https://www.instagram.com/davidperlmutter/

     

    Website: https://www.drperlmutter.com/

     

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    4 December 2023, 6:31 pm
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