In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to explore the science, benefits, and future of testosterone therapy. Shalin has been a driving force behind bringing Kyzatrex, an FDA-approved oral testosterone, to market—making testosterone therapy more accessible and effective for both men and women. From breaking down misconceptions to advocating for better access to hormone therapy, this conversation sheds light on how testosterone plays a crucial role in overall health and wellness.
Shalin shares his journey, discussing how his background in investments and his drive to bring valuable but overlooked health solutions to the mainstream led him to develop Kyzatrex. They dive into the challenges he faced in bringing this groundbreaking therapy to market, and how Marius Pharmaceuticals is striving to change the narrative around testosterone through education and advocacy.
We dive into:
Tune in to hear Shalin’s insights into the future of hormone therapy and the steps his team is taking to improve access and education around testosterone. This episode is a must-listen for anyone interested in health optimization, longevity, or understanding how testosterone therapy can impact overall quality of life.
Who is Shalin Shah?
Shalin Shah is a distinguished leader in the field of metabolic health, specializing in testosterone replacement therapy. As the Chief Executive Officer of Marius Pharmaceuticals, he was instrumental in the development and FDA approval of KYZATREX® (testosterone undecanoate) CIII Capsules, an oral testosterone treatment for adult men with low or no testosterone levels due to certain medical conditions.
With a global investment background, Shalin transitioned into healthcare with a mission to revolutionize the industry through metabolic health. His leadership at Marius Pharmaceuticals is marked by innovative strategies that prioritize consumer access and education. Under his guidance, KYZATREX has been launched via consumer-focused channels that include preeminent national healthcare institutions, private-equity backed medical practices, and national telemedicine platforms.
Shalin’s expertise extends beyond corporate leadership; he is an influential voice in longevity medicine and an advocate for reevaluating testosterone medication regulations. His efforts aim to reshape public perception and education on testosterone therapy and its significance for global health. He believes that oral testosterone replacement therapy has created a much-awaited paradigm shift which is critical for addressing the worldwide men’s (and women’s) health crisis, marked by declining testosterone levels and lower life expectancies. His message is that testosterone replacement therapy is not just about adding years to life, but also about adding life to years.
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Marius Pharmaceuticals - Discover more about accessible testosterone therapy options at Marius Pharmaceuticals. - https://mariuspharma.com
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In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Heidi Somers, the founder of Buffbunny Collection, a dynamic and empowering fitness and lifestyle brand that has taken the industry by storm. From growing up in a small town in Alaska to becoming a successful entrepreneur, Heidi’s journey is a testament to the power of resilience, self-belief, and authenticity.
Heidi opens up about her humble beginnings, including her early struggles with weight and body image, and shares how these experiences fueled her passion to help other women feel strong, confident, and stylish. She reflects on her decision to leave college and a pre-med path to pursue her dream, her challenges in starting a business from scratch, and the deep sense of purpose she finds in creating high-quality, functional activewear.
We dive into:
Tune in to hear Heidi’s inspiring journey and the strategies she used to build a thriving, values-driven business. Whether you're an entrepreneur, fitness enthusiast, or just seeking a boost of motivation, this episode is packed with practical advice and empowering stories to inspire your own journey.
Who is Heidi Somers?
Heidi Somers is the founder and CEO of Buffbunny Collection, a popular activewear brand dedicated to empowering women through fitness, fashion, and self-confidence. Growing up in a small town in Alaska, Heidi’s journey to success wasn’t easy. She faced personal challenges, including struggles with weight and self-acceptance, which fueled her passion to create a supportive community and high-quality activewear designed specifically for women. From humble beginnings on YouTube sharing fitness tips, Heidi built a multi-million dollar brand that resonates with women everywhere. Today, she’s celebrated for her transparency, grit, and dedication to helping women look and feel their best, both inside and out.
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In this enlightening episode of the Dr. Gabrielle Lyon Show, we dive deep into the world of youth training and the crucial role it plays in long-term health and athletic development. Joined by Judd Leinhard, former Army Ranger, collegiate lineman, and expert in speed training, we explore how training children differs from adults, debunk common myths, and reveal the surprising truth about building strength and resilience in kids.
We dive into:
If you're a parent, coach, or simply interested in the foundations of youth fitness and development, this episode will open your eyes to how early interventions in movement and strength training can significantly impact health and performance for years to come.
Who is Judd Lienhard?
Judd is the founder of MASS Method, a performance-based workout program dedicated to improving Movement, Athleticism, Strength, and Speed. He has worked as a Speed and Performance Coach in Austin, TX, for the past twelve years.
Judd's nontraditional approach to fitness was vastly shaped by his background as a collegiate athlete (middle linebacker at Truman State) and time in service as a US Army Ranger. During Judd's military career, he completed three deployments between Iraq and Afghanistan. Upon completion of his service obligation, Judd decided to focus his career efforts on coaching and fitness.
In addition to MASS Method, Judd coaches a private community dedicated to personal development based on his ethos: Always Be An Athlete. Judd is a proud dad, avid writer, history buff, and of course, a lifetime athlete.
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In this episode of The Dr. Gabrielle Lyon Show, I sit down with Dr. Layne Norton, a scientist and nutrition expert, to unpack the complex truths behind obesity, weight management, and diet myths. Together, we discuss what truly drives weight gain beyond the “calories in vs. calories out” model, exploring the impacts of hormones, metabolic rates, and lifestyle choices.
We dive into:
- How the body processes carbs, fats, and proteins
- Challenging the carb-insulin model of obesity
- Practical tips on meal structuring and muscle maintenance
- The significance of personalized diets and resistance training
If you’ve ever been curious about low-carb vs. high-carb diets, calorie counting, or how exercise impacts weight, this episode breaks it all down with science-backed detail. Don’t miss this eye-opening conversation packed with actionable advice for achieving sustainable, healthy weight loss and building lifelong fitness.
Who is Dr. Layne Norton?
As a self-proclaimed nerd who lifts heavy things, Layne completed his PhD in Nutritional Sciences with honors from the University of Illinois in 2010. His competitive athletic career highlights include four USA Powerlifting National titles (93kg weight class), most recently winning gold at the 2024 Powerlifting America National Championships (93kg).
Layne helped popularize flexible dieting and online nutrition coaching using evidence-based methods, coaching over 1700 clients. In recent years, Layne has focused on ways to share his knowledge with people on a wider scale, including building a coaching team, writing books, developing a nutrition coaching app and educational courses, and launching Outwork Nutrition, an evidence-based supplement company.
Layne’s passion is helping others achieve their goals through education and hard work.
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In this episode of the Dr. Gabrielle Lyon Show, I sit down with Dr. Vonda Wright, a pioneering orthopedic surgeon and women’s health advocate, to explore the powerful intersection of mobility, aging, and resilience. Dr. Wright shares her inspiring journey from growing up on a Kansas farm to becoming a leader in orthopedics, and how her non-traditional path shaped her approach to health and wellness.
We explore:
Whether you're curious about aging well, staying strong, or redefining your health at any stage of life, this episode is packed with practical advice, cutting-edge science, and inspiration to help you thrive.
Who is Dr. Vonda Wright?
Dr Wright is a practicing board certified Orthopaedic Sports Surgeon, Author, Speaker, Researcher and Innovator serving as a key opinion leader at the intersection of Musculoskeletal Aging & Longevity | Women’s Health | Sports Performance. Her clinical practice focuses on shoulder, hip and knee arthroscopy and advances the use of needle arthroscopy and orthobiologics. Widely recognized for her thought leadership, Dr Wright is a frequent media and conference expert and her innovative science-based approach is changing the lives of millions in mid-life.
In addition to treating active people and athletes of all ages and skill levels, she is a clinical champion for ideators in the biotech, sports innovation and longevity environments to develop innovation pipelines.She works to clarify and amplify great ideas through a deep clinical lens while applying entrepreneurial adventure principles to understand, evaluate and stimulate innovation.Harnessing the new science of aging and her decades of aging research, Dr Wrightdeveloped the Precision Longevity Experience, a bespoke concierge program for high capacity executives, surgeons and people seeking health optimization, peak performance and longevity.
Dr Wright trained at the University of Chicago, University of Pittsburgh andHospital for Special Surgery.She Served as University of Pittsburgh Orthopaedic Faculty and the medical director of the UPMC Lemieux Sports Complex fornearly20 years prior to building an orthopaedic department for the NorthsideHospital system in Atlanta.Dr Wright has spent her career caring for collegiate and professional athletes from football,soccer,world rugby, the PGA and professional ballet.
The founder & CEO of Precision Longevity, Dr Wright currently practices in Lake Nona Florida where she lives with her husband, 2x Stanley Cup champion Peter Taglianetti, the youngest of their blended family of 6 kids, her actively aging parents and 2 old dogs.
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The Musculoskeletal Syndrome of Menopause - https://doi.org/10.1080/13697137.2024.2380363
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In this episode of the Dr. Gabrielle Lyon Show, we dive deep into groundbreaking approaches for treating PTSD, anxiety, and depression with Dr. John How, an emergency physician turned mental health advocate. Dr. How introduces us to the Stellate Ganglion Block, a powerful and non-invasive procedure that's transforming how we manage trauma and mental health without relying solely on medications.
We explore:
If you or someone you love struggles with mental health challenges, this episode offers insight into innovative treatments that can provide long-term relief.
Who is Dr. John How?
Dr. John How is an accomplished board certified emergency medicine physician with a passion for healing trauma and aging in both the mind and the body.
He is the founder, and medical director of The How Clinic in Encinitas, CA where the focus is on treating the root cause of his patient’s problems. He and his team at The How Clinic use traditional and functional medicine combined with cutting edge treatments for pain and injury to combat the symptoms and causes of trauma and aging. These treatments include nerve hydrodissection, regenerative medicine therapies, hormone and nutritional optimization, as well as therapies to address sexual dysfunction.
He is a Medical Director at Stella Center, an interventional psychiatry practice. He and the team at Stella specialize in providing a world class combination of evidence-based treatments targeted at treating depression, PTSD, and chronic anxiety. These treatments include Spravato, ketamine infusion therapy, transcranial magnetic stimulation (TMS), an advanced stellate ganglion block (SGB) called the dual sympathetic reset (DSR), and integration therapy.
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In this episode of the Dr. Gabrielle Lyon Show, I sit down with the incredible Thais Gibson, an expert in attachment theory and personal development. Together, we dive deep into the fascinating world of attachment styles and explore how early childhood experiences shape our emotional patterns, relationships, and even our overall health.
We cover:
Whether you're looking to better understand your relationship dynamics or improve your mental and emotional health, this episode is packed with actionable insights and tools to help you build more secure, fulfilling connections.
Who is Thais Gibson?
Thais Gibson, counselor and co-founder of The Personal Development School, is THE leading expert in attachment theory and her cutting-edge research is extending the frontier of psychology with her modern Integrated Attachment Theory. It was widely accepted that your attachment style was set for life, but Thais’ research shows that you can actually CHANGE your attachment style, improving your romantic relationships, close family connections, and friendships. Thais is a powerhouse, recently appearing on The Mel Robbins Podcast, has over 230k subscribers on YouTube, more than 60k followers on Instagram, was a keynote speaker for Google’s International Women’s Day, and The Personal Development School has over 30,000 members in 115 countries.
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Join Dr. Gabrielle Lyon as she sits down with Dr. Jeremy Loenneke, an associate professor of exercise science at the University of Mississippi and one of the world’s leading experts in blood flow restriction (BFR) training. They discuss the science behind skeletal muscle adaptation, how BFR can help you get stronger without heavy weights, and why muscle growth and strength aren’t always the same thing.
Dr. Loenneke shares insights on how BFR works—using low loads to trigger muscle adaptation and growth—and the potential benefits for recovery, rehabilitation, and even everyday training for those wanting to avoid joint strain. They also explore some fascinating phenomena like cross-education, where training one side of your body can strengthen the other side.
Key Highlights:
Don’t miss out on these expert insights that can transform your approach to exercise and recovery. Let’s take your fitness knowledge to the next level!
Who is Dr. Jeremy Loenneke?
Dr. Jeremy Loenneke is an Associate Professor of Exercise Science at The University of Mississippi within the School of Applied Sciences. He received his MS in Nutrition and Exercise Science from Southeast Missouri State University and his PhD in Exercise Physiology from the University of Oklahoma. He is the director of the Kevser Ermin Applied Physiology Laboratory and his research group’s primary focus is on skeletal muscle adaptations to exercise with and without the application of blood flow restriction. His recent work has also focused on addressing whether or not muscle growth contributes to changes in strength with exercise. Dr. Loenneke is a Fellow of the American College of Sports Medicine and a member of the American Physiological Society. He has authored numerous peer-reviewed articles and is an Associate Editor for PLOS One, Peer J, and Research Quarterly for Exercise and Sport. He also serves on the editorial board for Sports Medicine and Medicine and Science in Sports and Exercise
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In this episode of The Dr. Gabrielle Lyon Show, I sit down with the incredible Cindy Eckert—serial entrepreneur, founder of Sprout Pharmaceuticals, and the driving force behind Addyi (commonly known as “the female Viagra”). Cindy shares her groundbreaking journey in advocating for women’s sexual health, challenging the medical system, and fighting for equal treatment in medicine.
Cindy reveals the startling double standards between male and female sexual health, recounting her experiences bringing Addyi to market and navigating the resistance she faced. Together, we dive deep into why women’s pleasure, health, and biology have been historically overlooked and undervalued, and why now more than ever, the conversation must change.
Key highlights:
If you want to learn more about the untold truths of women’s health and why this conversation is so critical, hit play and join us for this powerful discussion.
Who is Cindy Eckert?
Cindy Eckert is a self-made serial entrepreneur and fierce advocate for women, known for her bold leadership and mission to empower female entrepreneurs through her Pinkubator. Over her 24-year career in healthcare, Cindy has built and sold two companies for over $1.5 billion, including Sprout Pharmaceuticals, which introduced the first FDA-approved drug for low sexual desire in women, often called "female Viagra." After selling Sprout for $1 billion, she fought to reclaim the drug and relaunched it on her own terms. Cindy’s work, widely featured in major media, focuses on creating mission-driven companies with a profound impact, and she is committed to helping others achieve success.
What is ADDYI?
ADDYI is for premenopausal women with acquired, generalized hypoactive (low) sexual desire disorder who have not had problems with low sexual desire in the past, and who have low sexual desire no matter the type of sexual activity, the situation or the sexual partner. The low sexual desire is troubling to them and is not due to a medical or mental health problem, problems in the relationship or medicine or other drug use. ADDYI is not for use in men or to enhance sexual performance.
Your risk of severe low blood pressure and fainting is increased if you drink 1-2 standard alcoholic drinks close in time to your ADDYI dose. Wait at least 2 hours after drinking before taking ADDYI at bedtime. Your risk of severe low blood pressure and fainting is also increased if you take certain prescription, over the counter or herbal medications, or have liver problems. Low blood pressure and fainting can happen when you take ADDYI even if you don’t drink alcohol or take other medicines. Do not take if you are allergic to any of the ingredients in ADDYI. Allergic reactions may include hives, itching or trouble breathing. Sleepiness, sometimes serious, can occur. Common side effects include dizziness, nausea, tiredness, difficulty falling asleep or staying asleep and dry mouth. See full PI and Medication Guide, including Boxed Warning at addyi.com/pi or call 844-PINK-PILL.
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Sexual Dysfunction in Women - https://www.nejm.org/doi/full/10.1056/NEJMcp2313307?query=TOC&cid=DM2357883_Non_Subscriber&bid=-1796380385
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In this episode we sit down with Dr. Jordan Shallow, chiropractor, strength and conditioning coach, and founder of Prescript. Dr. Shallow works with top athletes from the NFL, NHL, UFC, and more, helping them stay injury-free and perform at their best.
We dive deep into the world of biomechanics and movement, discussing the critical importance of "physical empathy" — understanding how the body interacts with gravity — and why it’s key to both performance and injury prevention. Whether you're an elite athlete or just starting your fitness journey, Dr. Shallow’s principles can help you train smarter, stay injury-free, and optimize your movement for lifelong strength and vitality.
In this episode, you’ll learn:
Tune in to learn how biomechanics can be your secret weapon for strength, longevity, and injury-free training!
Jordan Shallow is a founder of Pre-Script, the foremost leader in exercise education for coaches, clinicians and trainers.
He's held positions at Apple's world headquarters as apart of their corporate medial team, as well as Stanfrod Univeristy in their sports performance department.
He currently operates as a founder, educator as well as concierege chiropractor and Strength Coach for athletes of all disciplines.
His Atheltes range from the NFL, MLB, NHL and Professional Tennis. Deploying his principles based approach from rehabilitation to world class performance.
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In this episode of the Dr. Gabrielle Lyon Show, we welcome back neurophysiologist and human performance expert, Louisa Nicola. Together, we explore the powerful connection between exercise, cognitive function, and the prevention of Alzheimer's disease. With cutting-edge insights from Louisa’s recent research, we dive deep into the impact of resistance training, cardiovascular exercise, and lifestyle interventions on brain health and longevity.
In this episode, you’ll learn:
Join us for a science-driven conversation on how you can optimize your brain health through exercise and actionable lifestyle interventions, and discover why Alzheimer's may now be an "optional" disease.
Who is Louisa Nicola?
Neurophysiologist and human performance coach, Louisa Nicola is the founder and head performance advisor of Neuro Athletics - an elite human performance consulting firm. Neuro Athletics provides top-tier education and coaching for the world's highest-profile athletes and executives, ensuring they achieve peak performance. Louisa graduated from the University of Sydney Medical School and is currently completing her Doctorate with the University of Washington.
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