Dr. Donald Layman is the OG in the field of protein and amino acids. Dr. Layman's expertise spans decades, and his insights have revolutionized our understanding of protein's role in health, from athletic performance to combating obesity, diabetes, and cardiovascular issues.

In this episode, Dr. Layman teaches you about the nuances between protein intake and amino acids, shedding light on the essential nine and synthesizable eleven amino acids crucial for our diets. Delving further, he and Dr. Stephanie explore the intricacies of protein quality, comparing animal and plant-based sources, and deciphering the optimal dosing for muscle growth and repair.

Don also unravels the mysteries surrounding carbohydrate load tolerance, navigating the fine balance between minimum and maximum carbohydrate intake for various training regimens. Additionally, they debunk myths surrounding aging, particularly in women, and the imperative role of protein consumption in perimenopause and menopause.

Episode Overview:
0:00 Intro/Teaser
3:36 Welcome Dr. Donald Layman
4:13 Exploring the Function of Muscle in the Body
11:43 Delving into Protein, Amino Acids, and Synthesis
15:07 Protein Needs and Aging Process
26:58 Protein Quality: Animal vs. Plant Proteins
34:01 Supporting Vegetarians and Vegans with Protein Intake
36:16 Child Neglect and Malnutrition
41:00 Regulation of mTOR and Carbohydrate Consumption
44:22 Muscle Potential and DNA Limits
54:07 Leucine, mTOR, and MPS
57:44 Protein Timing for Exercise
1:00:30 Carbohydrates and Protein Choices
1:03:58 Protein Target for Weight Loss
1:07:54 Protein Dosing Throughout the Day

Resources Mentioned:
Essential amino acids and muscle protein recovery from resistance exercise - https://journals.physiology.org/doi/pdf/10.1152/ajpendo.00466.2001
Metabolic Flux - https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/metabolic-flux
Exercise, protein metabolism, and muscle growth - https://pubmed.ncbi.nlm.nih.gov/11255140/
Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise - https://pubmed.ncbi.nlm.nih.gov/16896166/
Dietary protein distribution positively influences 24-h muscle protein synthesis in healthy adults - https://pubmed.ncbi.nlm.nih.gov/24477298/
Website: MetabolicTransformation.com
Forever Strong book - https://drgabriellelyon.com/forever-strong/

Bio:
Dr. Donald Layman is Professor Emeritus in the Department of Food Science & Human Nutrition at the University of Illinois at Urbana-Champaign. Dr. Layman served on the faculty at the University of Illinois from 1977 – 2012. Dr. Layman has been a leader in research about protein, nutrition for athletic performance, obesity, diabetes and cardiovascular health. Dr. Layman has over 120 peer-reviewed publications. He has received numerous awards for his research from the American Society for Nutrition and the National Institutes for Health and for his nutrition teaching. Dr. Layman served as Associate Editor of The Journal of Nutrition and the Journal of Nutrition Education and Behavior and on the editorial boards of Nutrition & Metabolism and Nutrition Research and Practice. Dr. Layman has an extensive consulting background including work with NASA, the Shriners Children’s Hospital, the US Air Force plus numerous food companies and organizations including Kraft Foods, Nestlé, Danone, Agropur, the American Egg Board, and the National Dairy Council. Dr. Layman earned his B.S. and M.S. degrees in chemistry and biochemistry at Illinois State University and his doctorate in human nutrition and biochemistry at the University of Minnesota.  

We are grateful to our sponsors:

BODYBIO
BodyBio PC is a liposomal phospholipid complex designed to nourish your cells for healthy aging, optimal brain function, gut health, a better metabolism, and more. Prioritizing your cellular health is absolutely foundational for your well-being as you age. You can get started and save 15% off your first order with code BETTER at checkout at https://bodybio.com/BETTER

TIMELINE
Feeling tired and having no energy does not have to be your fate. Mitopure is a supplement and skin health line that helps improve energy at the level of the mitochondria so that you can continue to engage in the activities you love. Go to https://timelinenutrition.com/better and use code BETTER to get 10% off your order.

BIOPTIMIZERS
If you want to get all your magnesium in one supplement, you will love Magnesium Breakthrough. Each supplement itself is 500 milligrams of magnesium, which I feel is such a great dosage as a great baseline for most women. So head on over to https://bioptimizers.com/better and use code BETTER for 10% off of any order, but make sure that the magnesium breakthrough is in your cart.

Biohacking expert Aggie Lal joins this episode for a dynamic conversation about cycle syncing for women's health. With Dr. Stephanie's expertise in nutrition and Aggie's comprehensive approach to biohacking, they delve into topics ranging from menstrual cycle variations to stress management techniques.

Explore how nutrition, fasting, and training can be tailored to different phases of the menstrual cycle, and gain insights into emotional fluctuations and stress mitigation strategies. Whether you're a seasoned health enthusiast or new to the concept, this episode offers invaluable tips for optimizing wellness through cycle syncing.
Episode Overview
1:17 - Introducing Biohacking Bestie, Aggie Lal
2:43 - The Role of Women in Biohacking
6:59 - Embracing Feminine Energy
8:27 - Feminine Energy in Strength Training
14:11 - Shifting from Skinny to Strong1
4:14 - Lifting Weights and Cycle Training
19:02 - Training According to Menstrual Cycle
27:16 - Fasting Framework for Women
31:13 - Importance of Auto-Regulation in Health and Fitness
35:30 - Breaking Free from Masculine Ideals
36:51 - Embracing Femininity and Lifestyle Balance
37:20 - Period Power Beyond Reproduction
44:06 - Microfasts and Eating Patterns
44:37 - Nutrition, Metabolism, and Stress Management
51:43 - The Healing Power of Forgiveness
56:48 - Embracing Play and Pleasure
1:02:20 - The Teacher-Student Energetic Shift

Bio:
Aggie Lal is a renowned public figure, best-selling author, certified nutrition and health coach, podcast host, TV personality, and TEDx speaker. With  more than 1.5 million social media followers and a vast audience across multiple channels, Aggie has become highly influential in the areas of health, biohacking, personal development, entrepreneurship, and travel & lifestyle. Find out more at https://biohackingbestie.com/

Resources Mentioned:

https://biohackingbestie.com/products/biohack-like-a-woman

https://higherselfacademy.co/

Insights into Dr. D’Agostino’s 72-hour fasting experience - https://ketonutrition.org/insights-into-dr-dagostinos-72-hour-fasting-experience/

40 Years of Zen - https://40yearsofzen.com/

We are grateful to our sponsors:

TIMELINE

Feeling tired and having no energy does not have to be your fate. Mitopure is a supplement and skin health line that helps improve energy at the level of the mitochondria so that you can continue to engage in the activities you love. Go to https://timelinenutrition.com/better and use code BETTER to get 10% off your order.  

NEUROHACKER

High NAD levels help our bodies by creating energy, maintaining healthy DNA, and protecting our cellular health. You can try Qualia NAD risk-free for 100 days by going to https://neurohacker.com/better and use the code BETTER at checkout to get 15% off of your order.

BEAM MINERALS

Cold plunges are so useful for muscle healing and recovery, which is why they're so good when they're done on the same day as a workout. But if your mineral stores are low, you're not going to get the full recovery benefits that a cold plunge might offer. So next time you're doing your cold plunge take a Beam Mineral shot for an extra boost. Head over to https://beamminerals.com and use the code BETTER at checkout to save 20% off of your first order. 

Jessica Berman, the Chief Marketing Officer of BodyBio, delves into the fascinating world of seed oils, omega-6s, omega-3s, and their impact on our bodies' composition and overall health.

In this episode, Jessica and Dr. Stephanie journey through the scientific landscape, dissecting terms like linoleic acid and ALA, and debunking myths surrounding the vilification of seed oils.

Moving beyond the surface, they also explore the role of butyrate, its activation of GLP-1 agonists, and its profound implications for weight loss and body composition. Jessica sheds light on how the fatty acid needs of women evolve during pivotal life stages like perimenopause, pregnancy, childbirth, and breastfeeding.

Episode Overview:
0:00 Intro/Teaser
2:28 Butyrate and GLP-1 Agonists
3:21 Brain Health and Perimenopause
10:03 Essential Fatty Acids Pathway
10:51 Nuanced Conversation on Seed Oils
13:05 Scientific Illiteracy on Social Media
15:21 Evening Primrose Oil Benefits
17:04 Omega-3 Precursor ALA
17:48 Importance of EPA and DHA
19:03 The Balance of Essential Fatty Acids
20:01 Caviar as a Source of EPA and DHA
21:04 Phospholipid Form of Fish Oil
23:01 Liposomal Delivery and Absorption
24:31 Omega Fatty Acids and Health
27:55 Women's Health in Perimenopause
31:07 Changes in Linoleic Acid Concentration
32:38 Importance of Phosphatidylcholine in Detoxification
34:21 Detoxing from Mold Exposure
36:53 Clearing Mold Toxins with Essential Fatty Acids
37:56 Impact of Essential Fatty Acids on Behavior
39:34 Benefits of Essential Fatty Acids for Kids
42:02 Therapeutic Dosing of Essential Nutrients
46:54 Resistant Starches and Butyrate Production
48:11 Butyrate in Colon Health and Immune Function
51:47 Butyrate for GI Health and Inflammation
54:16 Using Essential Fatty Acids for Long COVID
58:23 Therapeutic Dosage for Mold Recovery
1:01:52 Where to Find BodyBio Products

Bio:
As the CMO of BodyBio, Jess leads all internal and external efforts in building the BodyBio brand and footprint across all social channels and expanding distribution both in the U.S. and internationally with the company’s trusted partners. In the last few years alone, Jess and her team have successfully managed consumer-driven marketing campaigns that have collectively generated over 55MM digital impressions across all social channels in the last 24 months. Jess has also been instrumental in securing partnerships with leading medical doctors and functional medicine specialists all of whom have endorsed BodyBio recommending its line of products to their patient network.

Resources mentioned:
BodyBio - https://bodybio.com/BETTER
Dietary linoleic acid and risk of coronary heart disease: a systematic review and meta-analysis of prospective cohort studies - https://pubmed.ncbi.nlm.nih.gov/25161045/
Jennifer Fisher Kitchen - https://www.instagram.com/jenniferfisherkitchen/
A banana a day could keep cancer at bay - https://www.leeds.ac.uk/news-health/news/article/5128/a-banana-a-day-could-keep-cancer-at-bay

We are grateful to our sponsors:

SUNLIGHTEN

I am incredibly bullish on sauna as a therapy for recovery, heart health, and overall aging well. It's crucial for hormonal balance and achieving a state of well-being necessary for a strong physique and a strong mind. Visit https://www.sunlighten.com/BETTER/?utm_source=DrStephanieEstima&utm_medium=Partner&leadsource=DrStephanieEstima&utm_campaign=DrStephanieEstima and use code BETTER to get a discount.

BODYBIO

BodyBio PC is a liposomal phospholipid complex designed to nourish your cells for healthy aging, optimal brain function, gut health, a better metabolism, and more. Prioritizing your cellular health is absolutely foundational for your well-being as you age. You can get started and save 15% off your first order with code BETTER at checkout at https://bodybio.com/BETTER

ONESKIN

It’s time for a radical shift in skin care. This year I am doubling down on skin health and OneSkin is one of the ways I am getting my 40-year-old skin to behave like 20-year-old skin. Visit https://www.oneskin.co/?utm_source=partner&utm_medium=podcast&utm_campaign=BETTER and use the code BETTER at checkout to save 15%.

Carolina Reis Oliveira’s journey is as impressive as her expertise in skin care. In this episode, she dives deep into the science of skin aging. Along with Dr. Stephanie, she explores and explains both intrinsic and extrinsic factors, from cellular processes to environmental exposures. Carolina also shares insights into inflammation, peptide therapy, and the transformative potential of innovative compounds like OS-01.

OneSkin is getting to the root cause of skin aging with OS-01, a novel peptide that targets cellular senescence. OS1 influences cellular repair pathways and increases epidermal thickness. Explore face and body products at https://www.oneskin.co?utm_source=partner&utm_medium=podcast&utm_campaign=BETTER and use code BETTER at checkout to save 15%. 

Drawing from her team's research, Carolina discusses tangible results in reducing skin aging, offering hope for conditions like hyperpigmentation and rosacea. We explore strategies to stay ahead of the aging curve, aiming for what Carolina calls "escape velocity"—a state where we not only halt aging but reverse its effects.

Episode Overview:
0:00 Intro/Teaser
0:01:29 Interview with Carolina Oliveira
0:03:10 Skin Aging Mechanisms and Peptide Therapy
0:04:28 Intrinsic Mechanisms of Skin Aging
0:08:21 Intrinsic Aging Factors and Genetics
0:10:15 Cellular Senescence and Aging
0:13:11 Autophagy and Aging
0:14:37 Xenomorphic vs. Senolytic Compounds
0:16:18 Discovery of OS1 Peptide
0:19:12 Safety and Validation of OS1 Peptide
0:20:53 Human Clinical Studies on OS1 Peptide
0:25:00 Effects of OS1 on Skin Health
0:29:31 Specific Formulations for Eye Cream
0:31:01 Tailored Skincare for Different Areas of Body
0:36:39 The Science of Hyperpigmentation and Skincare
0:40:14 Combining Acids, Peptides, and Skincare
0:44:15 Consumer Awareness and Integrity in Skincare
0:47:57 The Importance of Antioxidants in Skincare
0:51:52 The Future of Skincare: Lip Treatments
0:53:43 Innovations in Sunscreen Technology
0:56:53 Prioritizing Skin Health Over Immediate Results
0:59:26 Maintaining Integrity in the Skincare Industry

Bio:
Carolina Oliveira, CEO and co-founder of OneSkin. Holds a Ph.D. in stem cell biology and tissue engineering, is a co-inventor of 5 patents and co-author of numerous scientific publications. She relocated from Brazil to Silicon Valley in 2016 to found OneSkin, a fast-growing longevity company developing products to promote skin age reversal by targeting a central driver of aging, the accumulation of senescent cells. Carolina and her team are disrupting the outdated anti-aging skincare industry with their groundbreaking research around skin and longevity.

Resources mentioned:

OneSkin: https://www.oneskin.co/ and use code BETTER at checkout to save 15%.

About Carolina Reis Oliveira, Ph.D.: https://www.oneskin.co/pages/our-story

The science: https://www.oneskin.co/pages/science and https://www.oneskin.co/pages/publications

We are grateful to our sponsors:

EMBR

I absolutely love this for my perimenopausal and menopausal women who are experiencing hot flashes and then the shivering that happens afterward. Go to https://embrlabs.com/products/embr-wave-2?rfsn=7896910.951991&discount/DRSTEPHANIE?redirect=/products/embr-wave-2 and use DRSTEPHANIE for 15% off of the Ember Wave 2. It is a bracelet (I got it in rose gold) and I love it.

FATTY15

Essential fatty acids create better skin, hair, nails, repair age-related damage to cells, and activate pathways that regulate sleep and mood. You can get an additional 15% off of their 90-day subscription starter kit if you go to https://fatty15.com/better and use code BETTER at checkout.

BIOPTIMIZERS

If you want to get all your magnesium in one supplement, you will love Magnesium Breakthrough. Each supplement itself is 500 milligrams of magnesium, which I feel is such a great dosage as a great baseline for most women. So head on over to https://bioptimizers.com/better and use code BETTER for 10% off of any order, but make sure that the magnesium breakthrough is in your cart.

Dr. Stephanie Estima dives into the invigorating world of sauna therapy and its myriad of health benefits. With a focus on the heart, Dr. Stephanie unpacks research revealing how regular sauna use can dramatically reduce the risk of sudden cardiac death and coronary heart disease, particularly emphasizing the practice's significance for women during perimenopause and menopause.

From the calorie-burning prowess of infrared saunas to the muscle and cognitive enhancements attributed to heat shock proteins and nitric oxide, this episode is a comprehensive guide to incorporating sauna therapy into your wellness routine for improved metabolism, cardiovascular health, and overall well-being. Join Dr. Estima as she shares both scientific insights and personal experiences an try out your own sauna today. 

Episode Overview:

0:00 Intro/Teaser
1:11 Making Informed Health Decisions
4:09 Benefits of Infrared Saunas
7:28 Effects of Repeated Sauna Use
12:19 Sauna Use and Cardiovascular Health
15:33 Benefits of Sauna on Heart Health
18:25 Sauna's Impact on Brain Health
22:33 Understanding Perimenopause and Growth Hormone
25:15 Heat-Induced Muscle Growth (Hyper Hypertrophy)
29:55 Sauna for Enhanced Muscle Preservation
31:53 Saunas and Nitric Oxide for Health
32:38 Endorphins and Fitness
39:17 Dr. Stephanie's Sauna Routine & Benefits
41:01 Evening Sauna Routine for Recovery

Resources Mentioned:

Clinical Effects of Regular Dry Sauna Bathing: A Systematic Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941775/

Correlations between Repeated Use of Dry Sauna for 4 x 10 Minutes, Physiological Parameters, Anthropometric Features, and Body Composition in Young Sedentary and Overweight Men: Health Implications: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360547/

Arterial stiffness during whole‐body passive heat stress in healthy older adults: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503298/

Effects of regular sauna bathing in conjunction with exercise on cardiovascular function: a multi-arm, randomized controlled trial: https://pubmed.ncbi.nlm.nih.gov/35785965/

Turning Up the Heat: An Evaluation of the Evidence for Heating to Promote Exercise Recovery, Muscle Rehabilitation and Adaptation: https://pubmed.ncbi.nlm.nih.gov/29470824/

The influence of Finnish sauna treatments on the concentrations of nitric oxide, 3-nitrotyrosine and selected markers of oxidative status in training and non-training men: https://pubmed.ncbi.nlm.nih.gov/31950931/

A post-exercise infrared sauna session improves recovery of neuromuscular performance and muscle soreness after resistance exercise training: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10286597/

Effect of post-exercise sauna bathing on the endurance performance of competitive male runners: https://pubmed.ncbi.nlm.nih.gov/16877041/

Sauna use as a lifestyle practice to extend healthspan: https://pubmed.ncbi.nlm.nih.gov/34363927/

Sauna bathing is inversely associated with dementia and Alzheimer's disease in middle-aged Finnish men: https://pubmed.ncbi.nlm.nih.gov/27932366/

Does sauna bathing protect against dementia? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7560162/

How the sauna affects the endocrine system: https://pubmed.ncbi.nlm.nih.gov/3218898/

Stephanie's Sauna: https://www.sunlighten.com/BETTER/?utm_source=DrStephanieEstima&utm_medium=Partner&leadsource=DrStephanieEstima&utm_campaign=DrStephanieEstima

We are grateful to our sponsors:

CAROL BIKE

This is my favourite cardio for speed drills! Five minutes and done! One of the coolest things about the CAROL Bike is that it is AI driven so it gives you custom workouts based on your very own fitness level. For a limited time, you can get $100 off a CAROL Bike. Use the code BETTER at https://carolbike.com.

BODYBIO

BodyBio PC is a liposomal phospholipid complex designed to nourish your cells for healthy aging, optimal brain function, gut health, a better metabolism, and more. Prioritizing your cellular health is absolutely foundational for your well-being as you age. You can get started and save 15% off your first order with code BETTER at checkout at https://bodybio.com/BETTER

JASPR

Investing in quality air purification is about protecting your and your family's health and well-being because the majority of your exposure to outdoor air pollution occurs indoors. So go to https://jaspr.co/better and use BETTER at check out for a special deal for my podcast listeners. 

Dr. Vonda Wright shares invaluable insights into the musculoskeletal syndrome of menopause, unravelling the complexities of arthralgia, inflammation, and the impact of decreasing estradiol on our joints, bone density, muscle mass, and fat distribution. She and Dr. Stephanie explore the phenomenon of frozen shoulder, its prevalence in the female population, and effective strategies for managing and preventing it.

Dr. Vonda also unveils her cutting-edge training protocol for lifting heavy, emphasizing the importance of balanced upper and lower body workouts to promote strength and resilience. They also delve into the nuances of zone training, injury prevention, and the significance of stability and instability training in enhancing our physical prowess as we age gracefully.

Get ready to be inspired and empowered as Dr. Wright uncovers the secrets to optimizing muscle health and vitality during menopause. So grab your headphones and tune in to this enlightening conversation.

Episode Overview:

0:00 Intro/Teaser
0:01:29 Introduction to Muscles and Menopause
0:03:28 Dr. Vonda Wright's Menopause Story
0:13:41 Dr. Vonda's Menopause Experience
0:24:33 Advocating for Women's Health
0:31:31 Treatment Spectrum for Frozen Shoulder
0:37:45 Preventing Frozen Shoulder in Women
0:39:11 Preparing for Menopause
0:39:33 The Power of Heavy Lifting
0:42:08 The Importance of Rest Time
0:43:50 The Effort of Heavy Lifting
0:45:54 The Importance of Rest Periods
0:48:49 The Significance of Warm-Ups
0:50:25 Zone Two Training for Women
0:51:50 Sprinting vs. Zone Two Training
0:57:35 Mental Resilience in Sprinting
0:59:43 Strength, Stability, and Injury Prevention
1:09:26 Harnessing Muscle Satellite Cells
1:11:31 Stimulating Muscle Growth

Bio:

Dr. Vonda Wright is a double-boarded, fellowship-trained orthopedic surgeon and internationally recognized authority on active aging and mobility. Dr. Wright’s practice focuses on minimally invasive surgery for hip preservation, shoulder and knee reconstruction, cartilage restoration, orthobiologics, and the latest in injury prevention and performance optimization. An intra-preneur, Dr. Wright was the founding director of the Performance and Research Initiative for Masters Athletes (PRIMA) and her pioneering research in mobility and musculoskeletal aging is changing the way we view and treat the aging process. More at https://www.drvondawright.com

Resources Mentioned:

InSPIRe- Institute for Sports Performance and Innovative Research https://www.speaker.drvondawright.com/resources/research

HOT For Your Health podcast - https://podcasts.apple.com/ca/podcast/hot-for-your-health/id1055206993

Estrogen Matters book - https://estrogenmatters.com

HRT, Bioidenticals & Menopause: Benefits & Risks - https://drstephanieestima.com/podcasts/hrt-bioidenticals-menopause-benefits-risks/

The Yentl Syndrome - https://www.nature.com/articles/353383a0.pdf

Instagram - https://www.instagram.com/drvondawright/

YouTube - https://www.youtube.com/user/vondawright

We are grateful to our sponsors:

Peluva

I'm a fan of Peluva, the natural evolution in minimalist footwear from NYT bestselling author and founder of Primal Kitchen, Mark Sisson. These low-profile shoes are designed to let feet be feet. Your toes get the space they actually need to help you ambulate properly. This smart-looking shoe allows for proprioception and retraining of the toe and ankle mortise.  Peluva delivers comfort, function, and style so you can relax, realign, and strengthen your feet to build health with every step. Go to https://peluva.com/DRSTEPHANIE to get 10% off your entire order.

Primeadine

Autophagy, a cellular renewal and recycling process that mimics the benefits of fasting, tends to slow down as we age. That's where spermidine comes in. Wholly plant-derived spermidine promotes autophagy, as well as hormonal balance, healthy aging, energy, and hair growth. It also supports sleep quality; memory, cognition, and brain health; and skin and nail health. Primeadine captures the many benefits of this longevity molecule in capsule and powder form. I use it daily. Go to https://oxfordhealthspan.com/drstephanie to try it for yourself. Use code DRSTEPHANIE15 to save 15% off your order.

BON CHARGE

Whether you're an athlete looking to recover from intense workouts, a muscle mommy looking for some relief from the delayed onset muscle soreness, or just looking for relief from everyday muscle tension, the new Boncharge cold and heat therapy massage gun is your new best friend. Head over to https://BonCharge.com/better and use discount code BETTER at checkout for a 15% discount.

World-renowned neuroscientist Dr. Lisa Mosconi takes us on a profound exploration of menopause. Together with Dr. Stephanie, she delves into the intricate physiological and neurological changes that occur during the perimenopausal, menopausal, and postmenopausal phases.

In this episode, you will learn about the metabolic, vasomotor, and neurological shifts reshaping women's brains, unravelling the mysteries behind hot flashes, mood swings, and cognitive alterations. You will also discover the evolutionary significance of menopause and the vital roles grandmothers play in human communities.

From hormone replacement therapy nuances to empowering lifestyle interventions, this conversation offers invaluable insights for women navigating this transformative stage of life. Embark on a journey of understanding and empowerment, and gain a newfound appreciation for the resilience and adaptability of the female brain.

Episode Overview:

0:00 Intro/Teaser
5:04 Unveiling the Menopause Brain
15:08 The Neurological Impact of Menopause
34:41 Neuronal Development and Puberty
43:44 Pregnancy Brain Remodeling
51:26 Evolutionary Significance of Menopause
1:03:41 Neurological Changes Post-Menopause
1:04:39 Hormone Replacement Therapy Considerations
1:09:19 Estrogen and Progesterone Considerations
1:11:46 Types of Progestogens and Progestins
1:17:55 Hormone Options for Breast Cancer History
1:20:22 Limitations and Alternatives of Hormone Therapy
1:24:21 Future of Hormones: Designer Estrogens
1:24:33 Lifestyle Modifications and Clinical Trials
1:33:48 Exercise Routines and Preferences
1:34:58 Importance of Greens and Nutrients
1:39:20 Stress Reduction and Hormonal Balance

Bio:

Lisa Mosconi, PhD, is an associate professor of neuroscience in neurology and radiology at Weill Cornell Medicine and the director of the Women’s Brain Initiative and the Alzheimer’s Prevention Clinic at Weill Cornell Medicine/NewYork-Presbyterian Hospital. A world-renowned neuroscientist with a PhD in neuroscience and nuclear medicine from the University of Florence in Italy, Mosconi was listed as one of the seventeen most influential living female scientists by The Times and called “the Mona Lisa of Neuroscience” by ELLE International. She is the New York Times bestselling author of The XX Brain and Brain Food.

Website URL: https://www.lisamosconi.com/

Resources mentioned:

The Menopause Brain book - https://www.lisamosconi.com/the-menopause-brain
Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition - https://pubmed.ncbi.nlm.nih.gov/34108509/
Association of reproductive history with brain MRI biomarkers of dementia risk in midlife - https://pubmed.ncbi.nlm.nih.gov/34732544/
More research - https://www.lisamosconi.com/research
Women’s Brain Initiative - https://neurology.weill.cornell.edu/research/womens-brain-initiative

We are grateful for our sponsors:

BODYBIO

BodyBio PC is a liposomal phospholipid complex designed to nourish your cells for healthy aging, optimal brain function, gut health, a better metabolism, and more. Prioritizing your cellular health is absolutely foundational for your well-being as you age. You can get started and save 15% off your first order with code “BETTER” at checkout at https://bodybio.com/BETTER

CAROL BIKE

This is my favourite cardio for speed drills! Five minutes and done! One of the coolest things about the CAROL Bike is that it is AI driven so it gives you custom workouts based on your very own fitness level. For a limited time, you can get $100 off a CAROL Bike. Use the code BETTER at https://carolbike.com.

BEAM MINERALS

It's almost impossible to get all of your minerals from food alone (as much as you would like to). So, if you want to increase your mineral intake quickly and easily, try BEAM Minerals. Visit https://beamminerals.com/better and get 20% off sitewide.

Dr. Szal Gottfried’s latest book, "The Autoimmune Cure," serves as the focal point for their discussion, where they explore how trauma can manifest as autoimmunity, the distinct experiences of women in facing trauma, and practical approaches to healing. Drawing from personal experiences and clinical expertise, Dr. Sara and Dr. Stephanie navigate through the intricacies of autoimmunity, offering invaluable insights for women and their loved ones seeking holistic approaches to wellness.

Whether you're grappling with autoimmunity or simply curious about the intersection of trauma and health, this episode promises illuminating perspectives and actionable strategies for reclaiming vitality.

Episode Overview

0:00 Intro/Teaser
1:25 Revisiting Autoimmunity with Dr. Sarah Szal Gottfried
4:03 Diving Deeper into Trauma and Healing Practices
26:06 MDMA Assisted Therapy
43:43 Exploring Other Therapies
53:35 Fear of Losing Stress Productivity
57:19 Perimenopause as an Energetic Portal
1:08:43 Gratefulness for Trauma
1:11:58 Important Lab Tests
1:14:18 Key Inflammatory Markers
1:18:08 Adapting Exercise for Autoimmunity
1:20:44 The Benefits of Divorce

Bio

Sara Szal Gottfried MD is a physician, researcher, author, and educator. She graduated from Harvard Medical School and MIT, and completed residency at UCSF, but is more likely to prescribe a CGM and personalized nutrition plan than the latest pharmaceutical. Dr. Gottfried is a global keynote speaker and the author of four New York Times bestselling books about hormones, nutrition, and health. Her latest book is called THE AUTOIMMUNE CURE (March 2024). She is Clinical Assistant Professor in Dept. of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University, and Director of Precision Medicine at the Marcus Institute of Integrative Health. She takes care of executives and professional athletes. Her focus is at the interface of mental and physical health, N-of-1 trial design, personalized molecular profiling, use of wearables, and how to leverage these tools to improve health outcomes. Learn more at SaraGottfriedMD.com

Resources mentioned

THE AUTOIMMUNE CURE book - https://www.saragottfriedmd.com/
ACE test - https://www.saragottfriedmd.com/discover-your-ace-score/
Instagram - https://www.instagram.com/saragottfriedmd

We are grateful to our sponsors

BON CHARGE

Whether you're an athlete looking to recover from intense workouts, a muscle mommy looking for some relief from the delayed onset muscle soreness, or just looking for relief from everyday muscle tension, the new Boncharge cold and heat therapy massage gun is your new best friend. Head over to https://BonCharge.com/better and use discount code "better" at checkout for a 15% discount.

FATTY15

Essential fatty acids create better skin, hair, nails, repair age-related damage to cells, and activate pathways that regulate sleep and mood. You can all that and save an additional 15% off of a 90-day subscription starter kit if you go to fatty15.com/better and use code BETTER at checkout.

JASPR

Investing in quality air purification is about protecting your and your family's health and well-being because the majority of your exposure to outdoor air pollution occurs indoors. So go to https://jaspr.co/better and use BETTER at check out for a special deal for my podcast listeners. 

Gabby Reece isn't just a volleyball legend; she's a beacon of inspiration in health and fitness, a podcast host, a corporate speaker, a New York Times best-selling author, a devoted wife, and a nurturing mother. With a storied career as Nike's first female spokeswoman and a former professional beach volleyball player, Gabby embodies athleticism and grace.

In this enlightening episode, Dr. Stephanie delves into Gabby's multi-faceted life, exploring her ventures like Laird Superfoods alongside her husband, Laird Hamilton. They also uncover the essence of womanhood through Gabby’s experiences as an athlete, entrepreneur, and matriarch.

From navigating the transition from fitness model to sports icon to the intricacies of self-care and maintaining a thriving relationship, Gabby shares invaluable wisdom gained from her journey. At 54, she radiates a profound understanding of life's lessons and generously imparts her insights.

Episode Overview

0:00 Intro/Teaser

1:16 Introduction to Gabby Reese: A Woman Who Conquered Life

3:08 Overcoming Assumptions and Biases

5:57 Being Authentic and Letting Go of Approval

9:16 The Importance of Genuine Relationships and Feedback

13:10 Finding Strength in Career, Family, and Personal Choices

16:17 The Value of Women in the Post-Reproductive Stage

21:43 Movement as the Key to Mental Capacity and Success

29:16 Hypoxic Training: Building Endurance Underwater

38:00 Different Types of Conflict: Dirty Fighting vs Clean Fighting

42:35 Being the Flower or the Farmer in a Relationship

45:50 Embracing Femininity and Challenging Stereotypes

51:13 The Power of Love and Connection

54:12 The Value of Quality Relationships Over Quantity of Time

57:04 The Intentional Ingredients and Philosophy Behind Laird Superfoods

1:00:08 Overcoming Obstacles in Product Formulation and Maintaining Integrity

1:03:10 Italy's Stringent Food Standards

Bio

Gabrielle Reece is not only a volleyball legend, but an inspirational health and fitness leader, podcast host, corporate speaker, New York Times bestselling author, wife, and mother. The former professional beach volleyball player and Nike’s first female spokeswoman is the definition of both athleticism and beauty. Gabby is a force to be reckoned with in the gym and on a microphone.


Resources Mentioned

Of Boys and Men: Why the Modern Male Is Struggling, Why It Matters, and What to Do about It - https://bookshop.org/p/books/of-boys-and-men-why-the-modern-male-is-struggling-why-it-matters-and-what-to-do-about-it-richard-v-reeves/18536826?ean=9780815739876

Laird Superfood - https://lairdsuperfood.com use code Gabby2024 for a special discount

Gabby’s podcast - https://gabriellereece.com/podcast/

Gabby’s website - https://gabriellereece.com

We are grateful to our sponsors

BODYBIO

BodyBio PC is a liposomal phospholipid complex designed to nourish your cells for healthy aging, optimal brain function, gut health, a better metabolism, and more. Prioritizing your cellular health is absolutely foundational for your well-being as you age. You can get started and save 15% off your first order with code “BETTER” at checkout at https://bodybio.com/BETTER

JASPR

Investing in quality air purification is about protecting your and your family's health and well-being because the majority of your exposure to outdoor air pollution occurs indoors. So go to  https://jaspr.co/better and use BETTER at check out for a special deal for my podcast listeners.

LMNT

We are a ski family and over this winter we have been using LMNT's Chocolate Medley. The chocolate chai is absolutely incredible with some boiling water and a splash of milk. And my kids love the chocolate mint with some hot water. If you head over to https://www.drinkLMNT.com/drestima you'll see an exclusive offer at the bottom of the page.

Dr. Sue Varma, board-certified psychiatrist or psychiatrist and Author of Practical Optimism, joins Dr. Stephanie in this episode and together, they explore practical strategies for bolstering mental fortitude, navigating emotions, and reclaiming control over one's time and mental space.

Drawing from Dr. Varma's extensive experience, including her groundbreaking work at the World Trade Center Mental Health Program, they discuss techniques to combat overwhelm, embrace the Joy of Missing Out (JOMO), and cultivate meaningful connections through friendship.

Whether you're seeking tools to regulate emotions, alleviate stress, or simply enhance your well-being, this episode promises invaluable insights for all. Tune in and embark on a journey toward resilience, empowerment, and practical optimism.

Episode Overview:
0:00 Intro/Teaser
1:15 Stress and Resilience
3:18 Practical Optimism: A Blend of Eastern and Western Philosophy
6:20 Validating the Human Experience
11:27 Medication and Calming Techniques for Inflammation
19:35 The Power of Observing Emotional "Tells"
27:08 Creating Distance from Negative Thoughts Through Mindful Observation
35:15 Reframing Cognitive Strategies for Self-Reflection
40:25 Finding Pleasure in Slowing Down and Appreciating the Senses
43:54 Slowing Down and Savoring the Present Moment
48:22 The Complexity of Emotions and Communication
50:30 The Therapeutic Power of Crying and Communication
54:20 Conflict Resolution: Resolving Conflicts Like Adults
58:03 Example of a Couple's Damaging Behavior in a Three-Legged Race
1:01:07 Communication Differences Between Men and Women
1:04:14 The Power of Feeling Supported and the Danger of Schadenfreude
1:09:54 The Importance of Relying on Others and Offering Help
1:13:28 The Importance of Choices, Work, and Sacrifices
1:20:12 Practical Optimism: The Art, Science, and Practice of Well-being

Bio:

Dr. Sue Varma is a board-certified psychiatrist who was the first medical director and attending psychiatrist at the World Trade Center Mental Health Program. She is also the go-to for all of the national morning shows on various topics related to mental health. Her first book examines how some people survive, even thrive, despite profound challenge, and how we can all optimize the things we have control over, while buffering ourselves from stress.

Website: https://www.doctorsuevarma.com/
Practical Optimism book: https://www.doctorsuevarma.com/book/

Resources mentioned:
It’s Not About the Nail - https://youtu.be/-4EDhdAHrOg?si=9zOcR3GR4E-9Ws5c

We are grateful to our sponsors:

COLDTURE

Coming soon…

BON CHARGE

I am doubling down on this year for my best skin ever. The Bon Charge Red Light Face Mask helps with glowing, younger, firmer-looking skin with minimal effort or time AND without really changing your usual day or night routine.  Head over to https://bonharge.com/better and use the discount code BETTER at checkout to get 15% off your entire cart.

TIMELINE NUTRITION

I'm in my mid-40s, and I've never felt more energized. One of the products I use to maximize this energy and help my muscles recover is Mitopure by Timeline. To feel your best, go to https://timelinenutrition.com/better and use code BETTER to get 10% off your order.

Cynthia Thurlow and Dr. Stephanie answer questions from both of their communities, covering topics ranging from managing hormones during breastfeeding while coping with insufficient sleep to issues concerning preconception and methods for cycle tracking.

They also dive into the best contraceptives for younger women, strategies for supporting detoxification, addressing fibrocystic breasts, navigating autoimmune conditions and fibromyalgia, and determining the intensity of workout routines.

There were also many questions about weight training, preferred pre-workouts, favourite supplements tailored for perimenopause and menopause, hormesis, and much more. Dr. Cynthia’s insights are as enlightening as ever, making this Ask Me Anything episode a must-listen for anyone on a journey toward optimal well-being.

Episode Overview:

0:00:00 Intro

0:01:15 AMA with Cynthia Thurlow: Hormones and Working Out

0:04:37 Strategies for Managing Sleep with a Breastfeeding Baby

0:10:23 Morning Routine for Moms vs. Perfect Morning Routine

0:18:59 Awareness and Observational Data for Infertility Journey

0:23:19 Choosing the Best Contraceptive for Younger Women

0:27:15 Different Types of Contraceptives and Potential Side Effects

0:30:51 Lack of Informed Consent for Contraception Options

0:36:47 Detoxification: Importance of Green Leafy Vegetables and Fiber Intake

0:40:42 Understanding Estrogen Metabolism and Liver Detoxification

0:45:59 Stimulating, Not Annihilating: Finding the Right Intensity

0:48:18 Finding the Balance Between Pushing Yourself and Overdoing It

0:52:36 Dealing with Increased Hunger During the Luteal Phase of Training

0:52:48 Listen to Your Body and Feed It During Luteal Phase

0:56:30 Experiment with Pre-Workout Meals and Coffee for Better Performance

0:59:50 Whey Protein and Creatine for Muscle Maintenance

1:03:34 Omega-3 and Other Key Supplements

1:04:32 Hormesis and Middle-Aged Women: Stress Tolerance and Benefits

1:08:22 Cold Plunge: Grit and Mental Resilience

Bio:

Cynthia is a nurse practitioner, CEO, and founder of the Everyday Wellness Project, and international speaker, with over 10 million views for her second TEDx talk (Intermittent Fasting: Transformational Technique). With over 20 years of experience in health and wellness, Cynthia is a globally recognized expert in intermittent fasting and nutritional health and has been featured on ABC, FOX5, KTLA, CW, Medium, Entrepreneur, and The Megyn Kelly Show.

Resources mentioned:

Dr. Shanna Episode - https://drstephanieestima.com/podcasts/phthalates-bisphenols-the-future-of-human-fertility-with-dr-shanna-swan/

Felice Gersh episode - https://drstephanieestima.com/podcasts/bioidentical-hormones-and-hrt-with-dr-felice-gersh/

Connect with Cynthia on:

Website - https://cynthiathurlow.com

Cynthia’s Books - https://cynthiathurlow.com/book-intermittent-fasting-transformation/

We are grateful to our sponsors:

LMNT

Now for a limited time you too can get the LMNT Chocolate Medley and enjoy them hot as I have been doing with this exclusive insider bundle for you. When you buy three boxes of any flavor, doesn't have to be the chocolate it can be any of the flavors that they offer, you are going to get the fourth box free. If you head over to https://www.drinkLMNT.com/drestima you'll see that exclusive offer at the bottom of the page.

AG1

If you want to take ownership of your health, start with AG1. Try AG1 and get a free one-year supply of vitamin D3 and K2 as well as five free AG1 travel packs which are a life send when you are on the road. Get this offer, with your first purchase, exclusively at https://www.drinkag1.com/stephanie

JASPR

Investing in quality air purification is about protecting your and your family's health and well-being because the majority of your exposure to outdoor air pollution occurs indoors. So go to https://jaspr.co/better and use BETTER at check out for a special deal for my podcast listeners.