This case presents a 19-year-old man with new onset dysuria and purulent urethritis. The discussion focuses on likely diagnoses and appropriate therapy.

This episode discusses a 64-year-old man who develops acute respiratory symptoms while climbing Mt. Kilamanjaro. The discussion focuses on the likely diagnosis, pathophysiology and treatment.

This episode presents a 65-year-old man recently who was diagnosed with hepatocellular carcinoma. We discuss environmental risk factors for the development of malignancy.

This episode presents a healthy 45-year-old who loses consciousness while playing tennis and is found to have focal neurologic findings. We discuss the initial evaluation and acute therapeutic interventions.

This episode discusses recent advances in left ventricular assist devices and the clinical indications for this type of technological support.

Harrison's PodClass provides engaging, high-yield discussions of key topics commonly found on rotational and board exams in internal and family medicine. 

Harrison's PodClass provides engaging, high-yield discussions of key topics commonly found on rotational and board exams in internal and family medicine. 

Harrison's PodClass provides engaging, high-yield discussions of key topics commonly found on rotational and board exams in internal and family medicine. 

Harrison's PodClass provides engaging, high-yield discussions of key topics commonly found on rotational and board exams in internal and family medicine. 

Harrison's PodClass provides engaging, high-yield discussions of key topics commonly found on rotational and board exams in internal and family medicine. 

Learn more about this in Chapter 344: Cirrhosis and Its Complications

In this episode of Harrison's Podclass, Dr. Cathy Handy and Dr. Charlie Wiener tackle the case of a 62-year-old woman presenting with pruritus and a constellation of symptoms including fatigue, weight loss, and intermittent nausea. The discussion delves into the diagnostic process, highlighting key clinical findings such as jaundice, spider angiomata, and a nodular liver.

Dr. Handy and Dr. Wiener explore the implications of these findings, focusing on the differential diagnosis for cirrhosis and the potential underlying causes. The episode emphasizes the significance of antimitochondrial antibodies (AMA) in diagnosing primary biliary cholangitis (PBC), a condition characterized by chronic liver inflammation and bile duct destruction.

Listeners will gain insights into the histopathology of PBC, typical laboratory findings, and the treatment options available, including the role of Ursodeoxycholic acid and liver transplantation. The episode concludes with a brief review of alternative diagnostic tests and their relevance in the broader context of liver disease.

Tune in for a comprehensive discussion on diagnosing and managing liver conditions in an older adult, with practical insights for clinicians dealing with similar cases.