On Masters of Scale, iconic business leaders share lessons and strategies that have helped them grow the world's most fascinating companies. Founders, CEOs, and dynamic innovators join candid conversations about their triumphs and challenges with a set of luminary hosts, including founding host Reid Hoffman (LinkedIn co-founder and Greylock partner). From navigating early prototypes to expanding brands globally, Masters of Scale provides priceless insights to help anyone grow their dream enterprise.
To get the most out of your talent, you need to create an environment that allows them to thrive. Nobody knows this better than Indra Nooyi, who spent 12 years as the CEO of PepsiCo. Her drive to support talent underpinned the initiatives that transformed the company. Hear her conversation with host Reid Hoffman in this episode from our archive.
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In this encore episode of Rapid Response, we revisit a scientific breakthrough that set the internet ablaze: The ‘de-extinction’ of the dire wolf. While many celebrated Colossal Biosciences’ announcement, the experiment also sparked controversy throughout the scientific community — namely the ethics of birthing and re-wilding extinct animals, and whether Colossal’s dire wolf puppies are the real thing. Colossal’s co-founder and CEO Ben Lamm joined host Bob Safian to take us inside the dire wolf journey, revealing how the startup attracted a roster of celebrity investors, and what the company’s technology means for not only conservation and biodiversity, but potentially the future of human health.
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After serving as Chief Legal Officer and then CFO at Salesforce, Amy Weaver sought a new challenge. She is now CEO of Direct Relief, which she tells host Jeff Berman is "the largest, most efficient, most effective, and most impactful global humanitarian group that you may never have heard of.” Weaver reveals scale lessons from Salesforce and how she's now applying them to amplify Direct Relief's vital work.
Learn more about Direct Relief: directrelief.org
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This year delivered whiplash: geopolitics, tariffs, and technology all shifting at once. And heading into 2026, the disruption isn’t easing up. In this special episode, host Bob Safian distills five hard-won lessons from Rapid Response this year on how to lead when the ground won’t stop moving. You’ll hear standout moments from Brian Chesky, Clara Shih, Marc Lore, José Andrés, and more, with practical takeaways for turning uncertainty into advantage.
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With over two billion in annual revenue and nearly 7,000 employees, Gensler has cemented itself as a global icon in architecture and design. Host Jeff Berman talks with co-CEO Elizabeth Brink and global co-chair Andy Cohen about why the company has doubled down on a collaborative leadership model, the ways AI is disrupting their industry, and how they’re designing for the future of work.
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Can ChatGPT dethrone Gemini? Is Tim Cook capable of leading Apple into the next wave of AI? As 2025 winds down, journalist and podcast host Kara Swisher joins Rapid Response to cut through the noise and decode what’s really happening across OpenAI, Meta, Google, and more. Swisher also sizes up the state of Disney, Netflix, and the escalating bidding war for Warner Bros. Discovery. And in classic Swisher fashion, she doesn’t hold back — weighing in on Elon Musk’s eye-popping potential pay package, Mark Zuckerberg’s costly misfires at Meta, and what the future of AI means for human health and cognition.
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How does a country sliding toward autocracy affect its economy? Political scientist and author Barbara F Walter offers data-driven insights about why the murky middle ground between democracy and autocracy is bad for business. She talked with host Jeff Berman live on stage at the 2025 Masters of Scale Summit.
Walter’s book: https://bookshop.org/p/books/how-civil-wars-start-and-how-to-stop-them-barbara-f-walter/35f702a0af16f18a
Walter’s Substack: https://barbarafwalter.substack.com/
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In less than a decade, OnlyFans says it has grown into a business earning $7 billion a year. The digital platform is known for letting its 4 million creators share exclusive – often NSFW – content with more than 400 million paying users. So far, creators have earned $25 billion using OnlyFans. CEO Keily Blair revealed what’s next for the brand with host Jeff Berman live on stage at Web Summit in Lisbon.
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A recent New York Times headline — “Did Women Ruin the Workplace?” sparked a firestorm across social media. Bob Safian welcomes a leader pushing back on this notion with data and nuance: Alison Moore, CEO of Chief, the prestigious network for senior women executives. Drawing from an exclusive nationwide survey of women leaders, Moore unpacks how evolving career paths are being misread, why women-centered spaces remain vital, and the rise of the multihyphenate leader. As a former HBO executive, Moore also reveals how she’s applying lessons from Game of Thrones to Chief, and how she stays attuned to the cultural pulse, from AI to shifting leadership expectations.
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Danny Meyer is best known as the founder of Shake Shack and the legendary restaurants of his Union Square Hospitality Group in New York City. He joined host Jeff Berman in 2024 for the first Masters of Scale Live, presented by Capital One Business. Later in the conversation, Danny’s daughter, Hallie Meyer, joined them on stage. Hallie is busy scaling her own food venture, the gourmet NYC ice cream shop Caffè Panna. The Meyers offer invaluable insights on how to scale great experiences for customers and teams.
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This Thursday marks the 99th annual Macy’s Thanksgiving Day Parade, and Macy’s Inc. chairman and CEO Tony Spring joins Rapid Response with a behind-the-scenes preview of what to expect. It’s been a tumultuous year for the legacy retailer, shaped by new tariffs, shifting consumer habits, and the constant flip between “wartime” and “peacetime” leadership. Spring shares why his team is now on “version twenty-seven of the plan,” how Macy’s is entering the AI era, and what it really means to court the next generation of shoppers while staying grounded in “balance, not hype.”
Visit the Rapid Response website here: https://www.rapidresponseshow.com/
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