Medical advances have significantly improved the survival of preterm babies and term neonates with brain injuries due to environmental hypoxia or genetic causes. Anca Pasca, M.D., shares her work to understand the molecular mechanisms underlying neurodevelopmental disorders associated with fetal and neonatal brain injury. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39453]

The 2023 Kyoto Prize Laureate in Basic Sciences, Professor Elliott Lieb presents snapshots of his seventy-year journey through the world of science, first as a would-be engineer, then as a physicist and later as a mathematician and a mathematical physicist. In many encounters with colleagues in different areas of research he learned that mathematics and a mathematical perspective can be pivotal in developing our thinking about physics. This fundamental connection between mathematics and physics was not always accepted at the beginning of my career, and it was even vigorously denied by some mathematicians and physicists. Lieb mentions some of his work to illustrate the value of mathematical physics for theoretical physics and to pure mathematics, the first being the Polaron bound found with K. Yamazaki in Kyoto in 1957. Another is the "ice problem", where he calculated the number of ways to color a chess board with only three colors so that neighboring squares never have the same color. Series: "Kyoto Prize Symposium" [Science] [Show ID: 39424]

Join Los Angeles Times environment reporter and author of the new book California Against the Sea Rosanna Xia and Scripps Institution of Oceanography coastal resilience specialist Laura Engeman for a discussion on communicating the science and impacts of sea-level rise and California’s changing relationship with the ocean. Engeman will also discuss how Scripps Oceanography is advancing science and technology to understand sea-level rise across California and beyond. Xia will also do a reading from the book and be on hand afterward to sign copies and meet audience members.   Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 39648]

Born and raised in Hokkaido, Japan, Professor Ryuzo Yanagimachi, the 2023 Kyoto Prize Laureate in Basic Sciences, developed a love for nature. He became fascinated with the fertilization process of sea urchins. After studying the fertilization of fish and the life cycle of parasitic barnacles, he realized little was known about mammalian fertilization. He went on to train with Professor M.C. Chang at the Worcester Foundation for Experimental Biology, the father of mammalian in vitro fertilization and then started his own lab at the University of Hawai'i. His basic studies contributed to understanding the hidden capacity of sperm and eggs and overcoming human fertility problems. Professor Yanagimachi passed away in 2023 at the age of 95, just a few months before he was to receive his Kyoto Prize award. Dr. W. Steven Ward, Director of the Institute for Biogenesis Research at the University of Hawai’i will present Prof. Yanagimachi’s life and work. Series: "Kyoto Prize Symposium" [Health and Medicine] [Science] [Show ID: 39423]

Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]

Marking the one-year anniversary of the Global Astrobiotechnology Hub, an esteemed panel convenes to envision the future of space exploration and stem cell research. Central to their discussion is the imperative to enhance accessibility and expedite scientific inquiry in space. They advocate for a shift towards establishing regular access to space, enabling frequent dispatches of payloads and experiments. They highlight the pressing need to advance technology to democratize space research, opening doors for nontraditional researchers from industry, academia, and beyond. They emphasize the significance of scientist-astronauts who possess a nuanced understanding of research methodologies. Emphasizing the importance of public engagement, they underscore the need to disseminate research findings widely and mentor the upcoming generation of scientists. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39528]

As AI becomes more prevalent, many people are asking how it will impact health care. In this program, Dr. Ida Sim, Professor of Medicine and Computational Precision Health at UCSF and Cora Han, attorney and Chief Health Data Officer for University of California Health, discuss the issues surround health care and AI. Sim outlines the current thinking around the role of transparency and explainability in AI governance and oversight, and in earning and maintaining trust of various stakeholder communities. Han discusses AI governance efforts across UC Health, and state and federal efforts to develop resources for ensuring that AI systems are developed, integrated, and deployed in a trustworthy manner. Series: "UC Center Sacramento" [Health and Medicine] [Science] [Show ID: 39603]

Despite effective computer tutoring software, no adaptive tutoring system has been developed and open-sourced to the field. In this program, Zachary Pardos, Associate Professor of Education at UC Berkeley, talks about efforts to create more equitable access to adaptive learning technology with the introduction of the first open-source adaptive tutoring system based on Intelligent Tutoring System principles. This system, called Open Adaptive Tutor, and its adaptive textbook library, have been iteratively developed over three years. Pardos describes how this system can be used as a foundation for exploring integrations of generative AI and will share nascent results from their first evaluations of ChatGPT for content generation. Series: "UC Center Sacramento" [Science] [Education] [Show ID: 39583]

Permanent body modification is a unique and variable practice among humans, not observed in other mammals. Despite being costly and risky, it is regularly performed. Scientific understanding of this phenomenon is nascent, prompting a symposium aiming to assess current research status and prioritize questions for the next decade. The event brings together academics and industry practitioners, exploring historical and contemporary practices like tattooing, piercing, finger amputation, and cranial modification. The symposium aims to investigate the 'when' and 'where' of permanent body modification and understand the motivations behind it, considering personal justifications and scientific hypotheses. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Humanities] [Science] [Show ID: 39476]

Claudia H. Kawas, M.D., addresses Alzheimer's disease and related conditions in older adults, noting the challenge of accurate diagnosis and the resemblance of other brain conditions to Alzheimer's. She introduces "resistance" and "resilience," explaining how some individuals remain cognitively intact despite brain changes. Kawas suggests declining dementia risk due to improved vascular health management, emphasizing the complexity of cognitive decline and the need for further research. Series: "Brain Channel" [Health and Medicine] [Science] [Show ID: 39532]

Southern California’s giant kelp forests are ecosystems that are potentially vulnerable to the region’s warming waters, but unlike terrestrial forests, changes in these underwater ecosystems are largely invisible to most of us. Join biologist Mohammad Sedarat and artist Oriana Poindexter in an exploration of their collaboration on the aquarium’s new art exhibition, Hold Fast, an immersive journey through our local giant kelp forests. Learn how their unique perspectives are combined to provide visitors with insight into climate change through the lens of art. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 39556]