The highest-ranking government official yet, Homeland Security Secretary Alejandro Mayorkas told CNN "we know of no threat" to the American public, in regard to the unidentified drone sightings over parts of the U.S. Federal agencies are facing intense pressure to give the public more details on the drone sightings going on for weeks over neighborhoods as well as restricted sites and critical infrastructure. Plus, President-elect Trump has praised the polio vaccine as the “greatest thing,” but a lawyer has petitioned the FDA to revoke approval of the vaccine used in the United States. Turns out that attorney is now an adviser to Trump’s pick to run HHS, Robert F. Kennedy Jr. Senate Minority Leader Mitch McConnell, himself a polio survivor, issued a warning about the issue Friday that was apparently intended for Kennedy.

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Sources are telling CNN that authorities have executed as many as three search warrants in New York as part of their investigation into the killing of UnitedHealthcare CEO Brian Thompson. At least two of the warrants include the backpack found in Central Park and the burner phone found near where the shooting occurred, according to a law enforcement source with knowledge of the investigation. Anderson shares what we have learned so far, and what we still don't know about the suspect. Plus, what the White House said today about the mysterious drones flying at nighttime over many parts of New Jersey.

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New York police now say the 3D-printed gun that CEO killing suspect Luigi Mangione had when he was arrested in Pennsylvania this week matches shell casings at the crime scene. Mangione’s fingerprints also match those investigators found on items near the scene, NYPD Commissioner Jessica Tisch said on Wednesday. Plus, a clearer timeline on when Mangione’s mother reported him missing and when at that time she said she last spoke with him. And, for weeks, mysterious drones have been flying low over parts of New Jersey. Our Gary Tuchman has video of some of the drones and shares what officials are saying about the sightings.

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Tonight, a source tells CNN's John Miller that the alleged UnitedHealthcare CEO shooter made a to-do list for a killing, as well as notes justifying those plans. Law enforcement also said Mangione had a three-page handwritten “claim of responsibility” as police characterized his manifesto. In one notebook passage, Mangione concludes that using a bomb against his intended victim “could kill innocents” but shooting would be more targeted, musing what could be better than “to kill the CEO at his own bean counting conference." Plus, a tip from the public was the key to the apprehension of Luigi Mangione, Randi Kaye takes a look at other high-profile investigations that came to a close with the help of good Samaritans.

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We examine how the suspected New York CEO killer was caught and what the police found tying him to the crime. Plus, a look at the suspect’s background and why he was almost invisible to authorities in the days before his capture. Also, a report from inside Syria and what’s being found after the fall of its brutal dictator. 

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The NYPD told the New York Times investigators are looking into the possibility the gunman who killed UnitedHealthcare CEO Brian Thompson may have used what is known as a veterinary gun, a larger firearm used on farms and ranches. Also Friday, a backpack believed to belong to the suspect was found in Central Park, a law enforcement official told CNN. Plus, the race to identify the UnitedHealthcare CEO shooter is hardly the first time a manhunt captivated the nation's attention. What can high-profile investigations into the Boston Marathon bombing and DC Sniper tell us about how the current search might end? CNN's Brian Todd takes a look. 

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CNN is learning more details about the alleged gunman's movements prior to the fatal shooting of UnitedHealthcare CEO Brian Thompson. Police believe the gunman arrived in New York City on November 24th, 10 days before the shooting, a law enforcement official told CNN. He arrived at the Port Authority bus terminal in Manhattan and then went to a hostel on the Upper West Side of Manhattan. Earlier Thursday, the NYPD released new images of an unmasked “person of interest wanted for questioning” over the killing. Our law enforcement experts including CNN Chief Law Enforcement and Intelligence Analyst John Miller, former FBI Deputy Director Andrew McCabe, and former FBI Special Agent Bryanna Fox break down the latest developments in the case.

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Authorities in New York are searching for a killer tonight. A suspect was caught on video in the heart of midtown Manhattan shooting the CEO of UnitedHealthcare in cold blood with a pistol and what looks like a silencer. CNN Chief Law Enforcement and Intelligence Analyst John Miller and former FBI Deputy Director Andrew McCabe on the “brazen, targeted attack" and the continued manhunt. Plus, former secret service agent Jonathan Wackrow, who also has years of experience in private corporate security, on the threats against corporate executives and the business of protecting them.

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Pete Hegseth, President-elect Trump's pick for Defense Secretary, continues to draw doubts after several damaging reports on his alleged drinking problem, alleged sexist behavior, and alleged financial mismanagement in a job related to veterans. Hegseth is expected to sit for an interview with Fox News tomorrow, according to sources. Multiple GOP senators say he faces a tough road to win confirmation. Plus, new developments from South Korea, where the sudden declaration of martial law shocked the world, and the sudden end to it leaves more questions than answers about one of America's leading allies.

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President Joe Biden's decision to pardon his son Hunter has left some Democrats fuming over his previous repeated comments claiming he would never take that step. Kaitlan Collins, Jeffrey Toobin, David Axelrod and Shermichael Singelton discuss the President’s controversial decision. Plus, The New Yorker's Jane Mayer shares her reporting that Pete Hegseth was pushed out as the head of two veterans’ advocacy organizations after allegations of mismanagement and personal misconduct.

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Could President-elect Trump offer New York City Mayor Eric Adams a way out of his criminal prosecution once he’s back in the Oval Office? CNN's Chief Law Enforcement Analyst John Miller looks at how it could come together. And Randi Kaye reports on the new scene in South Florida where Trump's reelection has turned the Palm Beach area into the center of the MAGA universe.

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