With no identified cause or cure, sarcoidosis is a challenging disease that has a heterogeneous presentation and an unpredictable clinical course. A recent paper in Thorax examined the outcomes for patients grouped by pulmonary function phenotypes, race and sex. First author for the study, Dr. Michelle Sharp¹, joins social media editor Dr. Kate Diomede to talk through the findings.

Read the paper: Pulmonary sarcoidosis: differences in lung function change over time

1. Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

The PulmPEEPs are back with another journal club episode. Dr. Kristina Montemayor and Dr. David Furfaro are joined by Thorax education editor Dr. Christopher Turnbull, and journal club author Dr. Ewan Mackay. They discuss a handful of selected papers focussing on COPD, covering the global impact of different household fuels on lung disease, early signs of CT changes in smokers before the detection of COPD, and a trial of treprostinil for the treatment of COPD related pulmonary hypertension.

Links:

• Journal club
• Estimated health effects from domestic use of gaseous fuels for cooking and heating in high-income, middle-income, and low-income countries: a systematic review and meta-analyses
• BEACON: A Missing Piece of the Puzzle for Chronic Obstructive Pulmonary Disease
• A New Global Definition of Acute Respiratory Distress Syndrome
• Inhaled treprostinil in pulmonary hypertension associated with COPD: PERFECT study results

For more from the PulmPEEPs, visit their podcast's website. You can find them Twitter (@PulmPEEPs) and Instagram (pulmpeeps), and hear past episodes on Apple Podcasts and Spotify.

To submit a journal club article of your own, you can contact Chris directly - [email protected]

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

Lung conditions remain one of the biggest causes of death and cost the economy billions annually. Despite this they receive only 2.5% of total public research investment in the UK. The Asthma + Lung UK charity brought together a number of experts and stakeholders in an effort to improve the working approach to this problem. This group published a letter in Thorax recently with a number of recommendations. One of the authors, Dr. Samantha Walker¹, joins the podcast.

Links:

• Fixing lung health in the UK: accelerating respiratory research and innovation
• Asthma + Lung UK

1. Research and Innovation, Asthma + Lung UK, London, UK

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

The growing use of artificial stone has seen the emergence of an aggressive, progressive respiratory disease, which is causing silicosis in young people. Dr. Johanna Feary¹ ² joins Thorax's Dr. Kate Diomede in the studio, to discuss. They talk through some the UK's earliest cases, the background to this phenomenon, international response, and the broader history of silicosis as a disease.

Links:

• Artificial stone silicosis: a UK case series
• Relationship between cumulative silica exposure and silicosis: a systematic review and dose-response meta-analysis 

1. National Heart and Lung Institute, Imperial College, London, UK
2. Department of Occupational Lung Disease, Royal Brompton Hospital, London, UK

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

A special journal club episode featuring guest-hosts Dr. Kristina Montemayor and Dr. David Furfaro of the PulmPEEPs. They're joined in conversation with Thorax education editor Dr. Christopher Turnbull, and Dr. Imran Howell, author of a recent journal club article in Thorax. Focussing on the theme of airway disease, they discuss the four papers in Imran's roundup, covering topics from nutritional impact on tuberculosis rates to infant vaccination against RSV.

Links:

• Journal club
• Blood eosinophil-guided oral prednisolone for COPD exacerbations in primary care in the UK (STARR2): a non-inferiority, multicentre, double-blind, placebo-controlled, randomised controlled trial
• Nutritional supplementation to prevent tuberculosis incidence in household contacts of patients with pulmonary tuberculosis in India (RATIONS): a field-based, open-label, cluster-randomised, controlled trial
• The airway microbiome mediates the interaction between environmental exposure and respiratory health in humans
• Respiratory syncytial virus infection during infancy and asthma during childhood in the USA (INSPIRE): a population-based, prospective birth cohort study
  
  

For more from the PulmPEEPs, visit their podcast's website. You can find them Twitter (@PulmPEEPs) and Instagram (pulmpeeps), and hear past episodes on Apple Podcasts and Spotify.

To submit a journal club article of your own, you can contact Chris directly - [email protected]

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

A new clinical statement from the British Thoracic Society was recently published in Thorax. It describes a building-block approach for how to manage patients with tobacco dependency in a hospital setting. Thorax podcast host Dr. Kate Diomede speaks with two of the authors, Prof. Sanjay Agrawal (1) and Dr. Matthew Evison (2). 

Read the statement: Medical management of inpatients with tobacco dependency

Further reading:

• NCSCT online training
• NCSCT briefings and practice guidance

(1) Department of Respiratory Medicine, Glenfield Hospital, Institute for Lung Health, Leicester, UK

(2) Manchester University NHS Foundation Trust, Manchester, UK

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

What are the effects of high levels of social media consumption amongst young people? New research published in Thorax quantifies the impact that exposure to marketing on online platforms is having, showing a greater likelihood of smoking or vaping with greater time spent on these platforms. Thorax associate editor Prof. Nick Hopkinson (1) joins Dr. Kate Diomede to discuss the paper's findings.

Read the paper: Association of time spent on social media with youth cigarette smoking and e-cigarette use in the UK: a national longitudinal study 

(1) Prof. of Respiratory Medicine, Imperial College London, Respiratory Consultant, Royal Brompton Hospital, Associate Editor of Thorax, Chair of ASH (Action on Smoking in Health) UK Charity
https://twitter.com/COPDdoc

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

Asthma prevalence is increasing around the world, and is theorised to be due to a number of environmental factors. One such factor is a sensitivity to house dust mite (HDM) allergens, which is common in asthma patients. Dr. Klaus Bønnelykke (1) joins the podcast to speak with Dr. Kate Diomede about this topic, following the publication of the paper, "Genetic and T2 biomarkers linked to the efficacy of HDM sublingual immunotherapy in asthma".

(1) Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital, Copenhagen, Denmark

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

Socioeconomic deprivation is a driving factor in lung cancer rates. With the roll out of a national lung cancer screening programme in the UK, it's important that the right invitation strategies are used for reaching community members who may be at risk. This episode, Dr. Patrick Goodley (@patrick_goodley) joins host Dr. Kate Diomede to discuss the recent paper, "Invitation strategies and participation in a community-based lung cancer screening programme located in areas of high socioeconomic deprivation."

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

What impact do reproductive events, like menarche, miscarriage or menopause have on female lung health? Prof. Gita Mishra (1) joins Thorax host Dr. Kate Diomede to discuss this question. They consider how recurrent fertility issues can point to an increased risk of chronic obstructive pulmonary disease later in life, and how variance in oestrogen levels throughout the lifespan affect lung development. The conversation is centred around the recently-published study, "Female Reproductive Histories and the Risk of Chronic Obstructive Pulmonary Disease" (https://doi.org/10.1136/thorax-2023-220388).

(1) School of Public Health, University of Queensland, Australia

Relevant links:

A Life Course Approach to Women's Health (2nd ed):
https://academic.oup.com/book/46697

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.

(1) National Heart and Lung Institute, Imperial College London, London, UK

Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - Thorax.BMJ) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. We would love to hear your thoughts on the podcast, you can leave a review on Apple Podcasts or Spotify.