The Life Scientific

BBC Radio 4

Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future

  • 28 minutes 28 seconds
    Anna Korre on capturing carbon dioxide and defying expectations

    As the famous frog once said, it's not easy being green. And when it comes to decarbonising industry, indeed, reducing emissions of all sorts, the task is a complex one.

    Fossil fuels are used to manufacture some of mankind’s most ubiquitous products, from plastics to cement to steel; and even in areas where we’re trying to improve our footprint, there are repercussions. Mining lithium for electric car batteries isn’t exactly without impact. Add to the mix stories of corporations prioritising profits, and governments focusing on short-term popular policies – and it would be easy to feel disheartened.

    Professor Anna Korre says her role is to be the champion of science in this debate: providing clear evidence to help reduce environmental impacts, while allowing vital production processes to continue.

    Anna is an environmental engineer at Imperial College London and Co-Director of the university’s Energy Futures Lab. Her work has led to a risk model that's now used in mining operations around the world – and her current research into sub-surface CO2 storage could hold the key to decarbonising British industry. But as she tells Jim Al-Khalili, social and familial expectations when she was growing up in her native Greece meant her succesful career in engineering very nearly didn't happen...

    Presented by Jim Al-Khalili Producer by Lucy Taylor

    24 September 2024, 8:00 am
  • 28 minutes 22 seconds
    Rosalie David on the science of Egyptian mummies

    Rosalie David is a pioneer in the study of ancient Egypt. In the early 1970s, she launched a unique project to study Egyptian mummified bodies using the techniques of modern medicine. Back then, the vast majority of Egyptologists regarded mummies as unimportant sources of information about life in ancient Egypt. Instead they focussed on interpreting hieroglyphic inscriptions, the written record in papyrus documents and archaeological remains and artefacts. Rosalie David proved that the traditionalists were quite wrong.

    Professor David’s mummy research started at the Manchester Museum when she began to collaborate with radiologists at the nearby Manchester Royal Infirmary, taking the museum’s mummies for x-rays at the hospital. Her multi-disciplinary team later moved to a dedicated institute at the University of Manchester, the KNH Centre for Biomedical Egyptology. Over the decades, the team there has made remarkable discoveries about disease and medicine in ancient Egyptian society, providing a new perspective on the history of medicine and giving extraordinary insights into the lives of individuals all those years ago.

    Rosalie tells Jim Al-Khalili about her journey from classics and ancient history to biomedicine, including some of her adventures in Egypt in the 1960s. She talks about some of her most significant research projects, and the 21st Century forensic detective work on the mummy of a young woman which revealed a gruesome murder 3,000 years ago...

    Presented by Jim Al-Khalili Produced by Andrew Luck-Baker

    17 September 2024, 8:00 am
  • 28 minutes 29 seconds
    Peter Stott on climate change deniers and Italian inspiration

    In the summer of 2003, Europe experienced its most intense heatwave on record - one that saw more than 70,000 people lose their lives. Experiencing the effects whilst on holiday in Tuscany, climate scientist Peter Stott was struck by the idea that just maybe, he could use a modelling system developed by his team at the UK’s Met Office Hadley Centre, to study extreme weather events such as this very heatwave mathematically; and figure out the extent to which human influences were increasing their probability.

    That’s exactly what he went on to do - and, through this work and more, Peter has helped to shine a light on the causes and effects of climate change. His career, predominantly at the Met Office Hadley Centre, has seen him take on climate change sceptics and explain the intricacies of greenhouse gas emissions to global leaders. His work with the Intergovernmental Panel on Climate Change even earned him a share of the 2007 Nobel Peace Prize.

    But the biggest challenge remains: Peter talks to Jim Al-Khalili about whether humanity can adapt quickly enough to deal with the increasingly dangerous effects of our warming world...

    Presented by Jim Al-Khalili Produced by Lucy Taylor

    10 September 2024, 8:00 am
  • 28 minutes 25 seconds
    Ijeoma Uchegbu on using nanoparticles to transform medicines

    Imagine a nanoparticle, less that a thousandth of the width of a human hair, that is so precise that it can carry a medicine to just where it’s needed in the body, improving the drug’s impact and reducing side effects. Ijeoma Uchegbu, Professor of Pharmaceutical Nanoscience at University College London, has spent her career with this goal in mind. She creates nanoparticles to carry medicines to regions of the body that are notoriously hard to reach, such as the back of the eye and the brain. With clinical trials in the pipeline, she hopes to treat blindness with eyedrops, transform pain relief and tackle the opioid crisis. Ijeoma took an unconventional route into science. Growing up in the UK and in Nigeria, she tells Professor Jim Al-Khalili her remarkable life story, from being fostered by a white family in rural Kent, while her Nigerian parents finished their studies, to struggling to pay the bills through her PhD as a single mum with young children. So passionate is Ijeoma to spread her love of science, she’s even turned to stand-up comedy to help get her message across!

    Presented by JIm Al-Khalili Produced by Beth Eastwood

    3 September 2024, 8:00 am
  • 28 minutes 24 seconds
    Darren Croft on killer whale matriarchs and the menopause

    Darren Croft studies one of the ocean’s most charismatic and spectacular animals – the killer whale. Orca are probably best known for their predatory behaviour: ganging up to catch hapless seals or attack other whales. But for the last fifteen years, Darren Croft’s focus has been on a gentler aspect of killer whale existence: their family and reproductive lives . Killer whales live in multi-generational family groups. Each family is led by an old matriarch, often well into her 80s. The rest of the group are her daughters and sons, and grand-children. Especially intriguing to Darren is that female orca go through something like the menopause - an extremely rare phenomenon in the animal kingdom, only documented in just five species of toothed whales and of course in humans. Halting female reproduction in midlife is an evolutionary mystery, but it is one which Darren Croft argues can be explained by studying killer whales. Darren is Professor of Animal Behaviour at the University of Exeter. He talks to Jim Al-Kalili about his research on killer whales, his previous work revealing sophisticated social behaviour in fish, his life on the farm, and the downsides and upsides of being dyslexic.

    Presented by Jim Al-Khalili Produced by Andrew Luck-Baker

    27 August 2024, 8:00 am
  • 35 minutes 59 seconds
    Bill Gates on vaccines, conspiracy theories and the pleasures of pickleball

    Bill Gates is one of the world's best-known billionaires - but after years at the corporate coalface building a software empire and a vast fortune, his priority now is giving that wealth away. And his ethos for doing it has been shaped by science.

    Famed for co-founding Microsoft, in recent decades Bill’s attention has turned to philanthropy via The Gates Foundation: one of the largest charities in the world. Since its inception in 2000, the organisation's helped tackle issues around health, education, inequality and climate change in some of the world’s poorest countries, with an undeniable impact: from contributing to the eradication of wild poliovirus in Africa, to helping halve global child mortality rates within 25 years.

    But, as Jim Al-Khalili discovers, for a man with lofty ambitions and an even loftier bank balance Bill has surprisingly humble tastes - from cheeseburgers and a bingeable spy series, to a good game of pickleball...

    Presented by Jim Al-Khalili Produced by Lucy Taylor

    20 August 2024, 8:00 am
  • 35 minutes 38 seconds
    Kip Thorne on black holes, Nobel Prizes and taking physics to Hollywood

    The final episode in this series of The Life Scientific is a journey through space and time, via black holes and wormholes, taking in Nobel-prize-winning research and Hollywood blockbusters!

    Kip Thorne is an Emeritus Professor of Theoretical Physics at Caltech, the California Institute of Technology, and someone who’s had a huge impact on our understanding of Einsteinian gravity. Over the course of his career Kip has broken new ground in the study of black holes, and been an integral parts of the team that recorded gravitational waves for the very first time – earning him a share in the 2017 Nobel Prize for Physics.

    He went on to promote physics in films: developing the original idea behind Christopher Nolan’s time-travel epic Interstellar and, since then, advising on scientific elements of various big-screen projects; including, most recently, the Oscar-winning Oppenheimer.

    In a special edition of The Life Scientific recorded in front of an audience of London’s Royal Institution, Professor Jim Al-Khalili talks to Kip about his life and career, from his Mormon upbringing in Utah to Hollywood collaborations – all through the lens of his unwavering passion for science.

    Presented by Jim Al-Khalili Produced by Lucy Taylor

    6 August 2024, 8:00 am
  • 28 minutes 29 seconds
    Vicky Tolfrey on parasport research and childhood dreams of the Olympics

    It's summer - no really - and although the weather might have been mixed, the sporting line-up has been undeniably scorching - from the back-and-forth of Wimbledon, to the nail-biting Euros, to the current pageantry of the Summer Olympics.

    Next month the 2024 Paralympic Games get underway in Paris, involving the world’s very best para athletes; and Professor Vicky Tolfrey is at the forefront of the science that makes their sporting dreams a reality.

    Vicky is the Director of the Peter Harrison Centre for Disability Sport at Loughborough University, a hub for elite para-sport research. She’s worked with stars from the worlds of wheelchair athletics, basketball, rugby and tennis, amongst others – and in 2017, became the first European recipient of the International Paralympic Committee’s prestigious Scientific Award.

    She tells Professor Jim Al-Khalili about her work with elite para athletes, her experiences at major international sporting events, and her childhood dreams of becoming an Olympian herself.

    Presented by Jim Al-Khalili Produced by Lucy Taylor

    30 July 2024, 8:00 am
  • 28 minutes 21 seconds
    Dawn Bonfield on inclusive engineering, sustainable solutions and why she once tried to leave the sector for good

    The engineering industry, like many other STEM sectors, has a problem with diversity: one that Dawn Bonfield believes we can and must fix, if we're to get a handle on much more pressing planetary problems...

    Dawn is a materials engineer by background, who held roles at Citroën in France and British Aerospace in the UK. But, after having her third child, she made the difficult decision to leave the industry - as she thought at the time, for good. However a short spell working in post-natal services and childcare gave her new skills and a fresh perspective. This led to Dawn rehabilitating the struggling Women in Engineering Society and creating ‘International Women In Engineering Day’, which has just celebrated its 10th anniversary.

    Today, she’s Professor of Practice in Engineering for Sustainable Development at King’s College London, and the founder of Magnificent Women: a social enterprise celebrating the story of female engineers over the past century. She’s also President of the Commonwealth Engineers’ Council and has had her work supporting diversity and inclusion recognised with an MBE.

    Dawn talks to Professor Jim Al-Khalili about why 'inclusive engineering' should not be dismissed as tokenism, and why she's optimistic about the engineering sector's power to change the world.

    Presented by Jim Al-Khalili Produced by Lucy Taylor

    23 July 2024, 8:00 am
  • 28 minutes 39 seconds
    Raymond Schinazi on revolutionising treatments for killer viruses

    In recent decades, we've taken huge steps forward in treating formerly fatal viruses: with pharmacological breakthroughs revolutionising treatment for conditions such as HIV, hepatitis and herpes.

    Raymond Schinazi has played a big role in that revolution.

    Ray was born in Egypt, where his mother’s brush with a potentially deadly illness during his childhood inspired a fascination with medicine. His childhood was scattered: after his family were forced to leave their homeland and travelled to Italy as refugees, Ray ended up on a scholarship to a British boarding school - and subsequently went on to study and flourish in the world of chemistry and biology.

    Today, Ray is the Director of the Laboratory of Biochemical Pharmacology at Emory University in Atlanta, where he also set up the renowned Center for AIDS Research. His work in the early days of HIV studies led to drugs that many with the virus still take today; while his contribution to developing a cure for Hepatitis C has saved millions of lives around the world.

    Speaking to Jim Al-Khalili, Ray reflects on his route to success - and explains why he's confident that more big breakthroughs are on the horizon.

    Presented by Jim Al-Khalili Produced by Lucy Taylor

    16 July 2024, 8:00 am
  • 28 minutes 36 seconds
    Janet Treasure on eating disorders and the quest for answers

    From anorexia nervosa to binge-eating, eating disorders are potentially fatal conditions that are traditionally very difficult to diagnose and treat - not least because those affected often don’t recognise that there’s anything wrong. But also because of the diverse factors that can influence and encourage them.

    Janet Treasure is a Professor of Psychiatry at King’s College, London - where she's focused on understanding the drivers behind these disorders, to help develop more effective treatments. Her study of twins in the 1980s offered one of the earliest arguments of a genetic link to anorexia, rather than the purely psychological motivations accepted at the time; while her most recent work explores holistic ways to better treat these conditions.

    Speaking to Jim Al-Khalili, Janet explains the work that's revealed anorexia's roots in both body and mind - as well as how attitudes towards eating disorders are slowly changing.

    Presented by Jim Al-Khalili Produced by Lucy Taylor

    9 July 2024, 8:00 am
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