Exertional heat illness at its extreme may cause heat stroke and altered mental status (confusion, delirium, stupor, or unconsciousness), which can result in organ failure and death. Author Francis G. O’Connor, MD, MPH, discusses heat-related illness in athletes, including risk factors, prevention, symptoms, and management, with JAMA Associate Editor David Simel, MD, MHS. Current NWS Forecast Related Content:

• Heat-Related Illness in Athletes

New weight-loss drugs have transformed care for people with obesity. In this Clinical Reviews podcast, Robert F. Kushner, MD, MS, of Northwestern University Feinberg School of Medicine joins JAMA Deputy Editor Mary McGrae McDermott, MD, to discuss prescribing these drugs to improve health outcomes and minimize adverse effects in people with obesity. Related Content:

• Medications for Obesity

Medical practice accounts for 8% of carbon emissions in the US. Author Wendy Levinson, MD, discusses simple changes that clinicians can make to reduce adverse effects of health care on the climate and the environment with JAMA Deputy Editor Mary McGrae McDermott, MD. Related Content:

• Medical Practice and the Climate Crisis
• How Can Operating Rooms Be Greener?

Essential tremor is a common movement disorder. Author Binit B. Shah, MD, of the University of Virginia joins JAMA Deputy Editor Christopher C. Muth, MD, to discuss the diagnostic evaluation and treatment of essential tremor, including pharmacological, nonpharmacological, and surgical treatments. Related Content:

• Essential Tremor

The US is a global leader in introducing new medical products, but the ability to generate evidence to inform clinical practice in postmarket settings must improve. Insurers may have an important role to play. Robert M. Califf, MD, of the US Food and Drug Administration, discusses why and how payers could support evidence generation with JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content:

• Why Evidence Generation Should Matter to Payers and How They Can Help

What are the common signs and symptoms of celiac disease and how is this disease diagnosed and managed? Author Kerstin Austin, MD, from the University of Wisconsin-Madison, discusses this and more with JAMA Associate Editor David L. Simel, MD, MHS. Related Content:

• Diagnosis and Management of Celiac Disease

Hospitals are on the frontlines of the US gun violence epidemic, both through the treatment of shooting victims and as sites of firearm violence. At least 240 shootings occurred on US hospital grounds from 2000 to 2016 alone. Author Joseph Blocher, MPhil, JD, from Duke Law School talks about this and more with JAMA Network Open Editor in Chief Frederick P. Rivara, MD, MPH. Related Content:

• Firearm Policy in the Hospital Setting—Recognizing Health Care as a “Sensitive Place”
• State Approaches to Stopping Violence Against Health Care Workers

Interview with John M. Ruiz, PhD, USPSTF member and coauthor of Management of BMI in Children: US Preventive Services Task Force Recommendation Statement. Hosted by JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS. Related Content:

• Interventions for Weight Management in Children and Adolescents
• Interventions for High Body Mass Index in Children and Adolescents
• Interventions for High BMI in Children and Teenagers
• Treatment Interventions for Child and Adolescent Obesity

Severe pulmonary infections are a leading cause of death in adults worldwide. Romain Pirracchio, MD, MPH, PhD, of the University of California-San Francisco, joins JAMA Deputy Editor Kristin L. Walter, MD, MS, to discuss Low-Dose Corticosteroids for Critically Ill Adults With Severe Pulmonary Infections. Related Content:

• Low-Dose Corticosteroids for Critically Ill Adults With Severe Pulmonary Infections

Approximately 9% of US adults experience major depression each year, with lifetime prevalence nearly 17% for men and 30% for women. Effective first-line depression treatments include forms of psychotherapy and medication. Close monitoring significantly improves likelihood of treatment success. Gregory E. Simon, MD, MPH, discusses depression treatment with JAMA Senior Editor Karen E. Lasser, MD, MPH. Related Content:

• Management of Depression in Adults

Homelessness is detrimental to health and clinicians can play an important role in mitigating the deleterious effects of homelessness. Margot Kushel, MD, University of California, San Francisco, discusses this and more with JAMA Senior Editor Karen E. Lasser, MD, MPH. Related Content:

• Health Care for People Experiencing Homelessness