Can you use hate to make the world a better place?  

Daryl Davis, a world-class jazz musician, didn’t just confront hate—he dismantled it. By sitting down with over 200 Ku Klux Klan members, he inspired them to leave their robes behind. But this isn’t just a story about racism or redemption; it’s a story about the incredible power of human connection and the lessons it holds for all of us. 

In this special episode, Dave explores how Daryl turned impossible conversations into transformative breakthroughs. Together, they unpack the mindset shifts, emotional intelligence, and fearless curiosity that can break down barriers of all kinds—whether they’re rooted in bias, fear, or misunderstanding. 

Daryl’s approach to erasing hate is so unique, so impactful, that it may just change how you view conflict, compassion, and even your own health. 

What You’ll Learn: 

• How Daryl’s global upbringing shaped his fearless approach to conflict 

• Why eliminating hate starts with understanding, not opposition 

• The neuroscience of compassion and how it rewires your brain 

• How forgiveness can transform your health and happiness 

• A step-by-step framework for tackling impossible conversations 

Resources:  

2025 Biohacking Conference – https://biohackingconference.com/2025 

Daryl Davis's Book: Klan-destine Relationships (Go read it for free at your local library instead of buying on Amazon :)) 

Daryl Davis's Website – https://www.daryldavis.com 

Daryl Davis on Instagram – https://www.instagram.com/realdaryldavis/ 

Danger Coffee – https://dangercoffee.com 

Dave Asprey’s Website – https://daveasprey.com 

Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

Own an Upgrade Labs – https://ownanupgradelabs.com 

Upgrade Labs – https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com 

Sponsors: 

-Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. 

-Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. 

Timestamps: 

• 00:00 A Shocking Parade Experience 

• 00:38 Meeting the KKK: First Impressions 

• 01:06 Introducing Daryl Davis 

• 03:46 Daryl’s Unique Upbringing 

• 09:52 Confronting Racism: A Lifelong Quest 

• 14:16 The Power of Travel and Perspective 

• 18:25 A High School Encounter with Nazis 

• 21:12 Confronting the Klan Leader 

• 30:57 Changing Minds: A Personal Approach 

• 36:30 The Illusion of Latent Genes 

• 42:08 Collecting Klan Robes: A Symbolic Victory 

• 46:17 Facing the Klan: Staying Grounded 

• 48:27 Challenging Beliefs: Confronting Hate 

• 49:15 The Journey to Writing ‘Clandestine’ 

• 50:26 Introducing ‘The Klan Whisperer’ 

• 51:35 Reflections on Racism and History 

• 57:29 The Power of Forgiveness 

• 59:28 Freedom of Speech and Its Limits 

• 01:02:21 Personal Stories of Racism 

• 01:13:16 Cultural Understanding and Misunderstandings 

• 01:25:16 The Impact of Music on Memory 

• 01:29:02 Final Thoughts and Upcoming Events 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is AI About to Replace Your Doctor? Or Save Your Life? 

The tools that are reshaping healthcare will redefine medicine—and your life—in ways you’ve never imagined. Will artificial intelligence and regenerative therapies like stem cells and exosomes make doctors obsolete? Or will they finally unlock the secrets to living to 180? 

In this episode, Dave sits down with Dr. Pradeep Albert, a leader in regenerative medicine and AI-driven imaging, to explore the intersection of technology, longevity, and healing.  

Dr. Albert shares groundbreaking insights on how AI is revolutionizing medical diagnostics, replacing outdated systems, and empowering patients to take control of THEIR OWN health. He also dives deep into regenerative therapies—how PRP, exosomes, and stem cells are changing the game for injuries, inflammation, and aging.  

Can AI improve patient-doctor relationships? Are doctors becoming coaches instead of gatekeepers? And most importantly, how can you leverage these tools to outlive your peers and enhance every aspect of your health? 

What You’ll Learn: 

• Why 50% of people won’t make it past 76—and how to beat the odds 

• How AI is already better than doctors at diagnosing certain conditions 

• The truth about PRP, exosomes, and stem cells—and when to use each 

• The three rules of longevity every person needs to know 

• How your mindset and epigenetics can help you live longer and healthier 

Resources:  

2025 Biohacking Conference – https://biohackingconference.com/2025 

Dr. Pradeep Albert’s Book: Exosomes, PRP, and Stem Cells…Medicine – https://www.amazon.com/Exosomes-Stem-Cells-Musculoskeletal-Medicine/dp/B0C2S59S8K 

Dr. Pradeep Albert’s Book: Lifespan Decoded –https://lifespandecoded.com/ 

Dr Pradeep Albert’s Website – https://drpradeepalbert.com/ 

Danger Coffee – https://dangercoffee.com 

Dave Asprey’s Website – https://daveasprey.com 

Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

Own an Upgrade Labs – https://ownanupgradelabs.com 

Upgrade Labs – https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com 

Sponsors: 

ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. 

OneSkin | Go to https://oneskin.co/ and use code ASPREY15 for 15% off your purchase. 

Timestamps: 

• 00:00 – Introduction to AI in Medicine 

• 00:36 – The Role of AI in Longevity 

• 00:51 – Meet Dr. Pradeep Alpert 

• 01:11 – AI’s Impact on Healthcare 

• 02:07 – Changing Role of Doctors 

• 05:01 – AI in Medical Imaging 

• 06:37 – Orthopedics and AI 

• 09:19 – Longevity and Epigenetics 

• 14:16 – The Importance of Mindset 

• 29:08 – Trust in the Medical System 

• 43:18 – DIY Health and Longevity 

• 44:21 – The Future of Insurance and Medical Costs 

• 45:45 – Advancements in Imaging Technology 

• 47:26 – The Art of Physical Examination 

• 50:21 – Regenerative Medicine: PRP, Exosomes, and Stem Cells 

• 01:00:23 – Challenges in the US Medical System 

• 01:07:54 – The Role of AI in Medicine 

• 01:18:14 – Final Thoughts and Book Promotion 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Most people don’t think about their liver until it’s too late. 

In this episode, Dave sits down with Siggi Clavien, founder of de-liver-ance® & The Liver Clinic, to uncover the hidden superpowers of the body’s most underrated organ: the liver. This is a deep dive into why your liver is the ultimate game-changer for your energy, brain power, and longevity. 

Siggi reveals groundbreaking insights on reversing fatty liver disease, boosting detoxification, and harnessing the liver’s regenerative capabilities. From fighting brain fog to protecting against toxins, this episode will have you rethinking everything about how you treat your body. And yes, your liver could be the key to living a healthier, happier life. 

Siggi also shares the science and innovation behind de-liver-ance®, his groundbreaking herbal product designed to deliver the most powerful results in a safe, natural way. Backed by millions of dollars and years of research, de-liver-ance® is setting a new standard in liver health. 

Use code: DAVE at https://us.loveyourliver.com/discount/DAVE to get a discount! 

Dave and Siggi also explore cutting-edge strategies to supercharge your liver health using natural herbs, breakthrough science, and biohacking tools. 

What You’ll Learn: 

• Why your liver holds the key to longevity, energy, and mental clarity 

• How to reverse fatty liver disease—even if you’ve been told it’s irreversible 

• The truth about common liver-destroying habits you need to ditch now 

• Groundbreaking ways to protect and regenerate your liver for optimal health 

• The science behind de-liver-ance® and how it’s changing liver health forever 

• Simple, actionable strategies to boost detoxification and supercharge your body 

Resources:  

2025 Biohacking Conference – https://biohackingconference.com/2025 

de-liver-ance® – https://us.loveyourliver.com/discount/DAVE (Use code DAVE at checkout for a discount!) 

The Liver Clinic – https://theliverclinic.com 

Danger Coffee – https://dangercoffee.com 

Dave Asprey’s Website – https://daveasprey.com 

Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

Own an Upgrade Labs – https://ownanupgradelabs.com 

Upgrade Labs – https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com 

Timestamps: 

• 00:00 Intro 

• 00:00 Introduction and Liver Basics 

• 01:46 Guest Introduction and Liver Health Insights 

• 02:16 Understanding Liver Scans and Lab Panels 

• 05:13 Fatty Liver Disease: Causes and Consequences 

• 07:07 Diet and Liver Health 

• 09:47 Supplements and Liver Function 

• 11:53 Advanced Liver Health Strategies 

• 14:05 Biohacking and Liver Health 

• 17:41 Deliverance Supplement and Its Benefits 

• 23:12 Liver Health and Longevity 

• 31:12 Biohacking: The Path to Consciousness and Longevity 

• 32:29 The Liver: The Body’s Regenerative Powerhouse 

• 34:48 Gut Microbiome and Liver Health Connection 

• 35:59 Lipopolysaccharides: The Hidden Toxins 

• 40:44 Coffee: A Surprising Ally for Liver Health 

• 43:16 Mold Toxins: The Silent Liver Destroyers 

• 48:43 Hormone Health and the Liver 

• 52:19 Type 2 Diabetes, Menopause, and Liver Health 

• 52:43 The Impact of Lifestyle on Liver Health 

• 54:57 The Importance of Bile and Gallbladder Health 

• 58:06 Genetics, Toxins, and Liver Resilience 

• 01:06:25 Conclusion: Investing in Liver Health for a Better Life 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Will the next nuclear bomb be AI Superintelligence? 

The intelligence we’re building will reshape the world in ways we never imagined—for better or worse? But more importantly, what side will humanity take? 

In this episode, Mo Gawdat, bestselling author of Scary Smart and former Chief Business Officer of Google X, joins Dave to tackle the profound challenges and opportunities artificial intelligence presents. This isn’t about dystopian robots or tech hype—it’s about redefining what it means to be human in the age of machines. There’s hope, don’t worry!  

Mo dives into the reality of how AI is already shaping our behavior, our ethics, and even our potential for happiness. He reveals the critical need for aligning intelligence—human or artificial—with values that promote global abundance and collaboration. Dave and Mo mix data, philosophy, and bold visions, to show why our future depends on shifting from competition to cooperation. But most importantly, why all of this is going to make you a better YOU. 

What You’ll Learn: 

• The real reason AI is reshaping human behavior—and how to take back control 

• Why intelligence without ethics could lead to catastrophe 

• How abundance thinking can unlock limitless possibilities for humanity 

• The crucial mindset shifts leaders need to adopt before it’s too late 

• Practical insights for ensuring AI supports human flourishing, not destruction 

Resources:  

2025 Biohacking Conference – https://biohackingconference.com/2025 

Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW 

Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O 

Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/ 

Danger Coffee – https://dangercoffee.com 

Dave Asprey’s Website – https://daveasprey.com 

Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

Own an Upgrade Labs – https://ownanupgradelabs.com 

Upgrade Labs – https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com 

Sponsors: 

- Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  

- fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. 

Timestamps: 

• 00:00 The Ethical Dilemma of AI in Warfare 

• 00:31 Introduction to Part Two with Mo Gawdat 

• 00:58 AI and Human Happiness: A Complex Relationship 

• 03:18 The Power and Responsibility of Technology 

• 05:08 The Rise of AI and Its Impact on Society 

• 08:31 The Future of AI: Abundance or Destruction? 

• 19:53 The Role of Ethics in AI Development 

• 22:39 Conclusion and Final Thoughts 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Can Happiness Really Be Engineered? Mo Gawdat Says Yes—And Here’s How.  

I know what you’re thinking… ANOTHER episode on happiness? Haven’t we heard it all before? This one’s different. The code is cracked, and you’re about to learn exactly how it works. 

Joining us today is Mo Gawdat, bestselling author of Unstressable and former Chief Business Officer of Google X. Mo sits down with Dave to deliver a practical, science-backed approach to hacking your mind and body for lasting joy. 

Mo dives into the raw science behind happiness and stress—revealing how your brain runs on algorithms that you can actually reprogram. Discover why dopamine might be sabotaging your joy, how to decode the four types of stress, and biohacks that can flip the script on your mental and physical resilience. 

He also shares the deeply personal story of how he turned unimaginable tragedy into a global mission for happiness and purpose. Mo’s insights will challenge everything you thought you knew about living a fulfilled life. 

What You’ll Learn: 

• The happiness algorithm—and how to make it work for you 

• Why dopamine addiction is robbing you of joy (and how to fix it) 

• The four stress modalities and how to regain control 

• Biohacks that build resilience—like cold plunges, gratitude, and micro-habits 

• How small mindset shifts can create major life transformations 

And don’t miss Part 2, dropping in two days! Dave and Mo explore the intersection of happiness and AI, revealing how to get them both working FOR you instead of against you. 

Resources:  

2025 Biohacking Conference – https://biohackingconference.com/2025 

Mo Gawdat’s Book: Scary Smart – https://a.co/d/6DukqyW 

Mo Gawdat’s Book: Unstressable – https://a.co/d/hrbpY9O 

Follow Mo Gawdat on Instagram – https://www.instagram.com/mo_gawdat/ 

Danger Coffee – https://dangercoffee.com 

Dave Asprey’s Website – https://daveasprey.com 

Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

Own an Upgrade Labs – https://ownanupgradelabs.com 

Upgrade Labs – https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com 

Sponsors: 

Neurohacker | Go to https://qualialife.com/dave and use code Dave for 15% off. 

Quantum Upgrade | Go to https://quantumupgrade.io/Dave for a free trial. 

Timestamps: 

00:00 – Intro 

00:31 – Introduction to The Human Upgrade 

00:45 – Dave Asprey’s AI Background 

01:13 – Introducing Mo Gawdat and His Work 

01:51 – From Scary Smart to Unstressable 

02:40 – The Journey to Happiness 

13:10 – Understanding Stress and Its Mechanisms 

17:26 – The Four Modalities of Stress 

24:16 – Mental Stress and the Happiness Flowchart 

31:34 – Sources of Stress: Trauma, Obsessions, Noise, and Nuisances 

33:27 – Understanding Modern PTSD 

34:09 – The Role of Obsessions and Noise 

36:24 – Biohacking for Resilience 

37:58 – The Power of Gratitude 

40:12 – The Happiness Equation 

54:37 – Dopamine vs. Serotonin 

01:03:00 – The Benefits of Cold Therapy 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Does Calorie Restriction Even Work? What About the Carnivore Diet AND Fruit?  

Today we are excited to have Paul Saladino join us for a masterclass on food and diets. Dr. Saladino dives into the evolution of keto and carnivore diets, cutting through trends to focus on lasting health impacts. Dr. Saladino, widely recognized as CarnivoreMD, shares how his own diet shifted to include fruit and honey alongside animal-based nutrition, and why metabolic flexibility—not rigid rules—leads to better outcomes. Together, he and Dave challenge assumptions about long-term ketosis, examine its potential downsides, and explore how to optimize diets for energy, gut health, and longevity. 

They also tackle controversial topics like the risks of seed oils, the overhyped reputation of “health foods” like quinoa, and the critical roles insulin and nutrient density play in overall wellness. With insights on balancing mTOR, managing omega fats, and incorporating organ meats, this episode offers a nuanced perspective for anyone interested in biohacking, nutrition science, or simply eating smarter. 

What you’ll learn: 

• Why metabolic flexibility matters more than strict diet rules 

• The science behind long-term ketosis and insulin’s broader role in health 

• How common “health foods” could be doing more harm than good 

• The importance of nutrient-dense animal-based foods for gut and immune health 

• How to achieve optimal balance between fat types, mTOR, and longevity markers 

Resources:  

2025 Biohacking Conference – https://biohackingconference.com/2025 

Shop Paul Saladino’s Products – https://heartandsoil.co 

Follow Paul Saladino on Instagram – https://www.instagram.com/paulsaladinomd/ 

Paul Saladino’s Book: The Carnivore Code – https://www.amazon.com/Carnivore-Code-Unlocking-Returning-Ancestral/dp/035846997X 

Lineage Provisions – 100% Grass-Fed Beef Tallow – https://lineageprovisions.com/products/100-grass-fed-beef-tallow 

Danger Coffee – https://dangercoffee.com 

Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ 

Dave Asprey’s Website – https://daveasprey.com 

Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

Own an Upgrade Labs – https://ownanupgradelabs.com 

Upgrade Labs – https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com 

Sponsors: 

- Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. 

- LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave. 

Timestamps: 

• 00:00 Intro 

• 00:40 Paul Saladino’s Evolution in Diet 

• 01:21 Challenges of a Strict Carnivore Diet 

• 03:36 Reintroducing Carbohydrates 

• 05:32 Debunking Common Diet Myths 

• 13:49 The Problem with Calorie Restriction 

• 18:30 The Importance of Food Quality 

• 24:08 The Veganism Debate 

• 34:15 The Benefits of Organ Meats 

• 37:27 Foot Surgery and Bone Density 

• 39:23 Mineral Deficiency and Plant-Based Diets 

• 40:00 The Truth About Seed Oils 

• 41:10 Historical Studies on Seed Oils 

• 47:26 Mechanisms and Effects of Seed Oils 

• 52:33 Nicotine and Neuroprotection 

• 54:12 Oleic Acid and Longevity 

• 01:01:44 The Benefits of Animal Fats

• 01:02:32 Odd Chain Fatty Acids and Health 

• 01:11:07 Cheese and Dairy Considerations 

• 01:13:11 The Impact of Cheese on Health 

• 01:14:03 Protein Intake and Longevity 

• 01:14:54 Understanding mTOR and Its Effects 

• 01:17:35 Ideal Body Fat and Metabolic Health 

• 01:24:38 The Role of Omega Fatty Acids 

• 01:32:46 ApoB, Insulin Sensitivity, and Longevity 

• 01:43:09 Final Thoughts and Product Recommendations 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What are the oral hygiene tips that could save your life?  

Dave Asprey sits down with one of the most popular guests on the show, Naveen Jain, founder and CEO of Viome Life Sciences, to explore how your oral microbiome influences not just your dental health but your entire body. Naveen reveals groundbreaking insights into how imbalances in oral bacteria can trigger chronic inflammation, heart disease, and even cancer—and how understanding your unique microbiome can help prevent these risks. 

Discover why oral health goes far beyond brushing and flossing, how to optimize your oral microbiome for longevity, and why common mouthwashes may be doing more harm than good. Naveen also introduces cutting-edge solutions from Viome, including personalized oral lozenges and postbiotics, to elevate both your oral and overall health. 

In this episode, you’ll also uncover the exact foods to eat and avoid to live a longer, healthier, and more vibrant life. 

What you’ll learn in this episode: 

• The surprising link between your oral microbiome and chronic disease 

• Why bacterial diversity in your mouth is essential for overall health 

• How leaky gums drive systemic inflammation and increase health risks 

• The dangers of over-sterilizing your mouth and eliminating beneficial bacteria 

• Personalized solutions to improve oral and gut health with Viome 

• Actionable tips to optimize your oral microbiome for better longevity 

Resources:  

• 2025 Biohacking Conference – https://biohackingconference.com/2025 

• Viome Full Body Intelligence Test (Save $110) – https://www.viome.com/dave 

• Viome Instagram – https://www.instagram.com/viome 

• Learn More About Viome – https://viome.com 

• Danger Coffee – https://dangercoffee.com 

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ 

• Dave Asprey’s Website – https://daveasprey.com 

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

• Own an Upgrade Labs – https://ownanupgradelabs.com 

• Upgrade Labs – https://upgradelabs.com 

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com 

Sponsors: 

-Leela Quantum | Head to https://leelaq.com/DAVE for 10% off. 

-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. 

Timestamps: 

• 00:00 Introduction to Viome and Its Impact on Health 

• 00:53 Meet Naveen Jain: Visionary Behind Viome 

• 02:41 Understanding the Microbiome and Its Role in Health 

• 05:54 The Power of RNA Analysis in Personalized Health 

• 12:19 Diet, Microbiome, and Personalized Nutrition 

• 29:50 The Importance of Oral and Gut Health 

• 39:20 Debating the Benefits of Intermittent Fasting 

• 40:08 The Role of Gut Bacteria in Fasting and Diet 

• 42:12 Understanding Chronic Inflammation and Diet 

• 44:13 The Keto Diet Myths and Realities 

• 45:44 Oxalates and Superfoods What You Need to Know 

• 49:25 The Concept of Holobiont and Human Health 

• 56:21 The Five Pillars of Longevity 

• 01:02:04 The Importance of Quality Sleep 

• 01:05:18 Purpose and Community for a Longer Life 

• 01:09:48 Upcoming Topics and Final Thoughts 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is this the missing link in fertility? 

The vaginal microbiome could be the most overlooked factor in optimizing women’s health, from fertility and hormonal balance to preventing infections and improving quality of life. In this groundbreaking episode, Dave Asprey talks to Priyanka Jain, co-founder and CEO of Evvy, about how understanding and improving the vaginal microbiome can transform women’s health outcomes. 

Priyanka shares how Evvy is advancing women’s health through cutting-edge genomic research and AI-powered insights, offering solutions to challenges like bacterial vaginosis, yeast infections, recurrent UTIs, and even infertility. You’ll learn why this critical microbiome plays such a vital role, how hormonal changes and lifestyle impact it, and how personalized approaches can improve reproductive and overall health. 

This episode explores not just women’s health but also how understanding the vaginal microbiome can influence relationships, biohacking, and even groundbreaking fertility research. Don’t miss this deep dive into the science and solutions shaping the future of health. 

Here’s what you’ll learn in this episode: 

 • The critical role the vaginal microbiome plays in women’s health and fertility 

 • How hormonal changes affect vaginal health and microbiome balance 

 • The link between vaginal microbiome imbalances and conditions like bacterial vaginosis, yeast infections, and UTIs 

 • Evvy’s innovative approach to using AI and genomics for personalized health insights 

 • Practical tips for maintaining microbiome health, including probiotics, hydration, and hormone balance 

 • The connection between the vaginal microbiome and overall quality of life 

Resources:  

 • 2025 Biohacking Conference – https://biohackingconference.com/2025 

 • Shop at Evvy (Use coupon code DAVE for $10 off!) – https://shareasale.com/r.cfm?b=1862577&u=2810239&m=116251&urllink=&afftrack= (Use coupon code DAVE for $10 off!) 

 • Follow Evvy on Instagram – https://www.instagram.com/evvy 

 • Danger Coffee – https://dangercoffee.com 

 • Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ 

 • Dave Asprey’s Website – https://daveasprey.com 

 • Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

 • Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

 • Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

 • Own an Upgrade Labs – https://ownanupgradelabs.com 

 • Upgrade Labs – https://upgradelabs.com 

 • 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com 

Sponsors: 

- Calroy | Head to https://calroy.com/dave for an exclusive discount. 

Timestamps: 

 • 00:00 Trailer 

 • 00:35 Introduction to Vaginal Microbiome 

 • 01:12 Meet Priyanka Jain of Evvy 

 • 02:03 Understanding the Vaginal Microbiome 

 • 04:37 Challenges in Women’s Health 

 • 09:55 Impact of Lifestyle on Vaginal Health 

 • 11:22 The Role of Diet and Supplements 

 • 15:24 Sexual Health and Vaginal Microbiome 

 • 27:25 Menopause and Vaginal Health 

 • 31:23 Optimizing Vaginal Health 

 • 39:31 Exploring Women’s Health Data 

 • 41:17 The Role of Vaginal Microbiome in Fertility 

 • 43:44 Affordable Testing and Discount Offers 

 • 45:31 The Impact of Lubricants on Vaginal Health 

 • 46:20 Innovative Ideas for Probiotic Products 

 • 47:29 Audience Questions and Precision Medicine 

 • 48:04 The Importance of Data in Women’s Health 

 • 54:31 Marketing and Misinformation in Vaginal Health 

 • 01:06:34 The Connection Between Diet and Vaginal Health 

 • 01:12:49 Conclusion and Final Thoughts 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Is alcohol losing its grip as the go-to social drink? 

Enter kava—a centuries-old Polynesian plant that’s gaining global recognition for its ability to relax the mind, elevate mood, and enhance social connection without the toxic effects of alcohol. Kava, particularly in the form of TRU KAVA, is a psychoactive yet non-intoxicating drink that offers the perfect balance of calm focus and mental clarity. 

In this episode, Dave Asprey welcomes Cameron George, founder of TRU KAVA, to discuss why kava is becoming the drink of choice for those seeking a healthier, more connected lifestyle. Learn how kava impacts neurotransmitters like GABA and dopamine, enhances creativity and emotional grounding, and even helps the body recover from stress and trauma. Discover why kava is taking center stage in the biohacking and sober-curious movements as a new tool for wellness and connection. 

Here’s what you’ll learn in this episode: 

• Why 41% of Americans and 61% of Gen Z are drinking less alcohol 

• What kava is, how it works, and its history as a ceremonial and social beverage 

• The science behind kava’s calming and neuroprotective effects 

• How kava supports creativity, emotional resilience, and authentic social connection 

• Practical uses for kava, including stress relief, sleep enhancement, and travel recovery 

Resources:  

• 2025 Biohacking Conference – https://biohackingconference.com/2025 

• TRU KAVA – https://www.trukava.com 

• TRU KAVA Instagram – https://www.instagram.com/trukava 

• Danger Coffee – https://dangercoffee.com 

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ 

• Dave Asprey’s Website – https://daveasprey.com 

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

• Own an Upgrade Labs – https://ownanupgradelabs.com 

• Upgrade Labs – https://upgradelabs.com 

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com 

Sponsors: 

-Quantum Upgrade |Go to https://quantumupgrade.io/Dave for a free trial. 

-Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. 

Timestamps: 

• 00:00 Intro 

• 00:37 Introduction to Alcohol Trends 

• 01:57 Meet Cameron George and TRU KAVA 

• 02:29 What is Kava? 

• 05:03 Kava’s Effects on the Brain 

• 06:53 Kava vs. Alcohol 

• 08:54 Active Compounds in Kava 

• 10:10 Kava’s Safety and Standardization 

• 16:17 Kava in Social Settings 

• 21:28 Kava and Psychedelics 

• 31:26 Kava for Public Speaking and Anxiety 

• 34:04 Kava in the Workplace: Enhancing Team Creativity 

• 35:22 Kava and Libido: The Unexpected Benefits 

• 36:06 Biohacking with Kava: Energy Allocation and Community 

• 39:00 Kava’s Role in Meditation and Emotional Awareness 

• 42:04 Kava During Pregnancy: Safety and Traditions 

• 44:37 Kava’s Neuroprotective Properties: A Deep Dive 

• 45:49 Kava and EMF Sensitivity: A Surprising Connection 

• 48:39 Kava for Frequent Travelers: Enhancing Mitochondrial Health 

• 52:46 Kava and Metabolic Health: Fasting and Fat Burning 

• 57:14 Kava Products: Oils, Beverages, and Their Uses 

• 01:01:27 The Future of Kava: Social Impact and Cultural Integration 

• 01:05:28 Conclusion: The Potential of Kava in Modern Society 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Have we finally discovered the key to youthful energy, longevity, and cellular health? 

In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial function, enhances immune system resilience, and combats chronic inflammation. 

This episode goes beyond cutting-edge science. Dr. Singh reveals practical, real-world strategies to combat “inflammaging”—the chronic, low-grade inflammation that accelerates aging. Learn how fasting, gut health, and mitochondrial boosters like Urolithin A can rejuvenate your cells, fight fatigue, and supercharge your energy, vitality, and longevity. 

Here’s what you’ll learn in this episode: 

• What Urolithin A is and its role in mitochondrial health and cellular energy production 

• How to reverse “inflammaging” and reduce inflammation through nutrition, fasting, and biohacking 

• The connection between mitochondrial dysfunction and immune system aging 

• Real-life benefits of Urolithin A for energy levels, athletic recovery, skin health, and longevity 

• Why mitochondrial support is critical for combating aging and improving overall performance 

Resources:  

• 2025 Biohacking Conference – https://biohackingconference.com/2025  

• Timeline Nutrition -  https://www.timeline.com/dave to get 10% off your first order  

• Timeline Instagram – https://www.instagram.com/timeline_longevity/  

• Dave Asprey’s Website – https://daveasprey.com  

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books  

• Danger Coffee – https://dangercoffee.com  

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/  

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey  

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com  

• Own an Upgrade Labs – https://ownanupgradelabs.com  

• Upgrade Labs – https://upgradelabs.com  

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com  

Timestamps: 

• 00:00 Introduction to Longevity and Mitochondria 

• 01:28 The Role of Mitochondria in Immune Health 

• 03:36 Understanding Inflammaging and Immune Aging 

• 07:47 Measuring Immune Health and Inflammation 

• 13:33 Urolithin A: A Mitochondrial Booster 

• 16:46 Dosage and Effects of Urolithin A 

• 26:11 Urolithin A and Exercise Performance 

• 28:31 Urolithin A for Skin Health 

• 31:34 Collagen and Aging: The Role of MMPs 

• 33:27 Personal Experience with MMPs and Recovery 

• 35:04 Measuring MMPs and Their Impact on Longevity 

• 36:18 Skin Health and Urolithin A 

• 38:39 Exploring Urolithin A’s Broader Benefits 

• 40:33 Brain Health and Urolithin A 

• 43:33 Combining Supplements for Optimal Health 

• 45:54 Omega-3s and Mitochondrial Health 

• 46:51 Ketones, MCTs, and Urolithin A 

• 54:30 Final Thoughts on MitoPure and Supplementation 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Are exosomes the planet’s ultimate healing tool?! 

In this episode, Dave Asprey sits down with Harvard-trained physician Dr. Edward Park to explore the groundbreaking science of exosomes. Dr. Park, a pioneer in regenerative medicine and author of Exosomes: Songs of Healing, explains how these tiny cellular messengers are revolutionizing health and longevity by bypassing the limitations of stem cells. 

BUT this episode isn’t just about cutting-edge science. Dr. Park also shares profound insights into life, resilience, and emotional well-being, offering advice that goes far beyond medicine. From the power of forgiveness to breaking free of limiting beliefs, his perspective blends science, spirituality, and practical wisdom for living a better life. 

Here’s what you’ll learn in this episode: 

• How exosomes work and why they’re being called the future of regenerative medicine 

• The key differences between exosomes and stem cells—and which is better for healing 

• Real-life applications of exosome therapy for injuries, anti-aging, and overall health 

• The potential of exosomes to enhance brain function, reduce inflammation, and promote recovery 

• Dr. Park’s advice on emotional resilience, gratitude, and creating lasting change 

With over a decade of experience, Dr. Park shares compelling case studies, cutting-edge insights, and practical advice for anyone looking to upgrade their body, mind, and life. Whether you’re managing chronic pain, exploring anti-aging therapies, or seeking wisdom for navigating life’s challenges, this episode has something for everyone. 

Sponsors 

TRU KAVA | Go to https://trukava.com and enter code DAVE15 at checkout for 15% off 

Resources: 

• 2025 Biohacking Conference – https://biohackingconference.com/2025 

• Dr. Edward Park’s Website: Recharge Biomedical – https://www.rechargebiomedical.com 

• Dr. Edward Park’s Book: Exosomes: Songs of Healing – https://www.amazon.com/EXOSOMES-Songs-Healing-Ed-Park/dp/098260632X 

• Dr. Edward Park’s YouTube Channel – https://www.youtube.com/channel/UCpp9DlRArB1rKAWNwoouiTg 

• Dr. Edward Park on Instagram – https://www.instagram.com/dredpark/ 

• Dave Asprey’s Website – https://daveasprey.com 

• Dave Asprey’s Book: Smarter Not Harder – https://daveasprey.com/books 

• Danger Coffee – https://dangercoffee.com 

• Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ 

• Dave Asprey’s Linktree – https://linktr.ee/daveasprey 

• Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com 

• Own an Upgrade Labs – https://ownanupgradelabs.com 

• Upgrade Labs – https://upgradelabs.com 

• 40 Years of Zen – Neurofeedback training for advanced cognitive enhancement – https://40yearsofzen.com  

Timestamps: 

• 00:00 Introduction to Exosomes and Healing 

• 00:48 Understanding Exosomes: Stem Cell Communication 

• 01:19 Dr. Edward Park’s Insights on Exosomes 

• 02:47 Exosomes vs. Traditional Treatments 

• 04:44 Exosomes in Regenerative Medicine 

• 07:33 Cost-Effective Regeneration Protocols 

• 12:35 Exosomes for Hair Growth 

• 14:37 Stem Cells and Brain Health 

• 25:33 Banking Stem Cells for Future Use 

• 35:27 Epigenetic Age and Longevity Predictors 

• 37:48 CRISPR and Gene Editing: Risks and Benefits 

• 39:43 Basic Health Tips for Longevity 

• 41:02 Spirituality, Past Lives, and Healing 

• 42:50 Questioning Medical and Political Narratives 

• 47:54 The Importance of Free Speech 

• 01:07:40 The Role of Intuition in Medicine 

• 01:09:22 Conclusion and Final Thoughts 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.