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The Human Upgrade with Dave Asprey

Dave Asprey

For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life. 

  • 55 minutes 16 seconds
    Reversing Heart Disease Naturally: Top Cardiologist Shares Groundbreaking Hacks : 1207

    Get ready to upgrade your cardiovascular health in a way you’ve never heard of before. Dave Asprey sits down with Dr. Michael Twyman, a pioneering biohacking cardiologist who blends cutting-edge functional medicine with conventional wisdom to help you avoid heart attacks and strokes. If you think cardiovascular disease is inevitable, think again. Dr. Twyman reveals the hidden mechanisms behind heart disease, starting with the misunderstood role of plaque in your arteries and the essential yet underappreciated glycocalyx—a slippery gel-like coating that could be the key to preventing arterial damage. 

    From there, it’s all about prevention, prevention, prevention. Want to know how simple lifestyle tweaks can significantly reduce your risk of cardiovascular events? We’ve got the biohacks—grounding, sunlight exposure, cold plunges, and more—laid out for you in a step-by-step, easy-to-apply format. Dr. Twyman breaks down the crucial role of circadian biology and how aligning your body clock with natural light cycles can help protect your heart. Plus, learn why grounding might just be the ultimate, free anti-inflammatory tool you’ve been missing. 

    This episode isn’t just about tips and tricks—it’s a complete roadmap to understanding and optimizing your heart health. Dave and Dr. Twyman get into the nitty-gritty of lab tests you should be asking for, why exercise is only part of the solution, and how the current medical insurance model fails to protect your cardiovascular future. Don’t miss out on these life-saving insights that are rooted in both ancient wisdom and modern science. 

     

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    Timestamps and Highlights: 

    • 00:00 — Introduction to Cardiovascular Health 

    • 01:22 — Meet Dr. Michael Twyman 

    • 05:57 — Understanding Heart Attacks 

    • 08:09 — The Role of Glycocalyx in Cardiovascular Health 

    • 15:17 — Lifestyle Changes for Cardiovascular Health 

    • 24:32 — Exercise and Cardiovascular Health 

    • 27:58 — Effective VO2 Max Strategies 

    • 28:12 — Patient Exercise Goals and Time Management 

    • 29:12 — Thyroid and Cardiovascular Health 

    • 32:49 — Circadian Biology and Heart Disease 

    • 33:57 — Sunlight, Grounding, and Seasonal Health 

    • 38:49 — The Role of Statins in Cardiovascular Health 

    • 43:16 — Key Labs for Cardiovascular Risk Assessment 

    • 50:33 — Insurance and Preventative Health 

    • 54:35 — Conclusion and Final Thoughts 

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    3 October 2024, 9:00 am
  • 1 hour 2 minutes
    Sleep Smarter, Live Longer: Matthew Walker and Sleep Experts share Secrets to Better Sleep Performance : 1206

    Are you sleeping enough—or just enough to get by? In this episode of The Human Upgrade, Dave Asprey dives into the global sleep crisis and reveals why mastering your sleep is the most important biohack you can do for your health, performance, and longevity. This episode is your ultimate guide to transforming your rest and, by extension, your life. 

    First, sleep scientist Matthew Walker breaks down how sleep deprivation has become a global epidemic, slashing up to 20% of our sleep in the past century. He unpacks the dangers of too little sleep, including its direct link to increased mortality rates and cognitive decline, and discusses the optimal sleep duration for both quantity and quality. 

    Next, Peter Martone shifts the conversation to sleep posture and environment. He shares simple yet effective techniques for optimizing your sleep position to maximize deep, restorative rest. Learn how a small change in your pillow or bed setup can lead to dramatic improvements in your sleep quality and overall health. 

    Finally, Dan Gartenberg dives into the world of sleep biohacking. He reveals groundbreaking research on how sound waves can enhance your deep sleep and how controlling light exposure can unlock better rest. From sleep-tracking tech to environmental optimizations, Dan provides actionable tips to help you take your sleep game to the next level. 

    By the end of this episode, you’ll walk away with expert-backed strategies, biohacking secrets, and sleep science insights that will completely transform the way you sleep—and live. 


    Check out the Full Episodes here:  

    - Sleep is the Boss of You – Matthew Walker, Ph D | 616 

    https://www.youtube.com/watch?v=cxmtBy0YQjs 

    - Change Your Body Position To Get Better Sleep with Dr. Peter Martone | 819 

    https://www.youtube.com/watch?v=RKhA3iclRK0 

    - Sleep Need & Sleep Age Find Out Yours – Dan Gartenberg | 583 

    https://www.youtube.com/watch?v=XbxB67M-s2A 


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    Timestamps and Highlights: 

    • 00:00 Introduction: The ROI on Sleep 
    • 00:24 Global Sleep Loss Epidemic 
    • 01:43 Sleep Duration and Mortality Risk 
    • 06:23 The Importance of REM Sleep 
    • 12:47 Optimizing Sleep Quality 
    • 17:37 Technological Interventions for Better Sleep 
    • 19:02 Temperature Regulation and Sleep 
    • 21:03 Light's Impact on Sleep 
    • 24:44 Personal Sleep Hacks and Experiments 
    • 33:40 Understanding Lymphatic and Glymphatic Drainage 
    • 34:42 Debunking Side Sleeping Myths 
    • 35:30 The Importance of Cervical Alignment 
    • 37:07 Improving Sleep Quality with Neck Nest 
    • 38:00 Audience Questions: TMJ and Sleep 
    • 41:07 The Impact of Food and Temperature on Sleep 
    • 45:28 Enhancing Sleep with Sound and Technology 
    • 01:01:08 The Role of Cortisol in Sleep Quality 


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    1 October 2024, 10:00 am
  • 48 minutes 45 seconds
    Unlock the Master Molecule: Glutaryl for Superior Detox, Skin, and Energy : 1205

    Dave Asprey is joined again by glutathione expert Nayan Patel to explore the transformative effects of this “master antioxidant” glutaryl. From skin health and detoxification to energy production and mitochondrial function, glutathione plays a critical role in overall wellness. Nayan shares his cutting-edge research on topical glutathione delivery systems that are more effective than IV treatments and help combat oxidative stress. 

    The conversation touches on innovative applications of glutathione for skin lightening (yes, including the surprising trend of butthole bleaching), the impact of environmental toxins, and how to optimize glutathione levels to support longevity and performance. Whether you’re battling oxidative stress, looking to rejuvenate your skin, or just curious about how glutathione can boost your health, this episode has something for everyone. 


    Visit https://aurowellness.com/ and use code Dave10 to get 10% off your order! 


     Resources: 


     

    Timestamps and Highlights: 

    • 00:00 Introduction to an Unusual Topic 
    • 00:36 The Human Upgrade with Dave Asprey 
    • 00:52 The Importance of Glutathione 
    • 01:34 Introducing Nayan Patel and Glutaryl 
    • 02:05 Benefits of Topical Glutathione 
    • 02:36 Personal Health Journey and Skin Care 
    • 03:21 Deep Dive into Glutathione Technology 
    • 08:13 Glutathione and Skin Health 
    • 10:00 Vitamin C and Glutathione 
    • 17:54 Diet, Oxidative Stress, and Glutathione 
    • 20:26 Detox Reactions and Glutathione 
    • 24:26 Using Glutathione for Recovery 
    • 26:54 The Cost of Biohacking 
    • 27:26 Gene Therapy and Glutathione 
    • 28:20 Affordable Alternatives to IV Treatments 
    • 29:06 Endocrine Hormones and Glutathione 
    • 34:02 Sun Exposure and Skin Care 
    • 38:00 Morning and Night Skincare Routines 
    • 40:33 Telomeres and Anti-Aging 
    • 44:55 Hair Loss and Glutathione 
    • 47:12 Conclusion and Final Thoughts 

     

     

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    27 September 2024, 10:00 am
  • 1 hour 1 minute
    Sexual Mastery with the World’s Top Experts: Unlocking Pleasure, Performance, and Intimacy : 1204

    In this transformative episode of The Human Upgrade, three of the world’s foremost experts on sexual wellness—Kim Anami, Susan Bratton, and Emily Morse—explore the depths of sexual mastery, pleasure, and performance. This discussion uncovers the often-overlooked power of sexual energy as a source of personal growth, healing, and vitality. Whether you’re looking to enhance your pleasure, improve your intimate relationships, or explore new dimensions of intimacy, this episode serves as your ultimate guide to unlocking the full potential of your sexual energy. 

    Kim Anami delves into the profound ways sexual energy can be harnessed for personal transformation, teaching how to access life-changing orgasms and deeper intimacy. Susan Bratton brings her expertise to sexual biohacking and the latest technology that can enhance physical pleasure and performance. Emily Morse focuses on breaking down societal taboos around sex and providing actionable advice for better communication and connection with partners. 

    Together, these experts deliver a comprehensive guide to sexual empowerment, sharing actionable techniques that elevate both physical pleasure and emotional connection. By the end of this episode, you’ll have the knowledge to transform your sex life into a source of greater health, energy, and overall well-being. 

    Check out the Full Episodes here:  

    -The Science of Sex: Longevity, Pleasure & Performance - Susan Bratton | 1087 

    https://youtu.be/3idAK1D85cs 

    -Unleash Your Sexual Potential: Date Nights, Fantasies, and Healing in 'Smart Sex' with Emily Morse 

    https://youtu.be/WyzdS8H__yM 

    - From Holistic Sex to Vaginal Kung Fu with Kim Anami 

    https://youtu.be/zLs3OgwiDSU 


    Sponsors: 


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    Timestamps and Highlights: 

    • 00:00 Introduction to Life-Changing Experiences 
    • 00:32 Understanding Orgasm Challenges 
    • 01:33 Impact of Medications on Sexual Health 
    • 02:12 Physical Health and Sexual Arousal 
    • 02:56 The Dark Side of Birth Control Pills 
    • 06:30 Men's Role in Birth Control Decisions 
    • 07:10 Communication in Sexual Relationships 
    • 13:25 The Importance of Feeling Safe 
    • 16:37 Techniques for Deep Connection 
    • 21:26 The Orgasm Gap and Sexual Performance 
    • 27:02 Harnessing Sexual Energy for Transformation 
    • 33:31 Breathing Techniques for Sexual Energy 
    • 34:00 Vaginal vs. Clitoral Orgasms 
    • 34:36 The Power of Cervical Orgasms 
    • 34:58 Sexual Reflexology and Spiritual Rebirth 
    • 35:27 Personal Experiences with Orgasms 
    • 36:08 The Anami Guarantee 
    • 38:09 Spirituality and Sexuality 
    • 40:12 Historical Suppression of Sexual Energy 
    • 41:48 Impact of Fifty Shades of Grey 
    • 44:22 Pandemic Effects on Sexuality 
    • 46:01 Sex Toys and Their Benefits 
    • 49:26 Penis Pumps and Male Enhancement 
    • 01:01:40 The Importance of Nocturnal Erections 


    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    26 September 2024, 10:00 am
  • 1 hour 6 minutes
    Grounding and Earthing: The Science Behind Reconnecting with Earth for Optimal Health : 1203

    In this episode of The Human Upgrade, Dave Asprey sits down with Clint Ober, the pioneer of grounding and earthing technology. Together, they explore the profound effects of reconnecting your body with the Earth’s natural energy through grounding, revealing how this practice can reduce inflammation, optimize mitochondrial function, and enhance overall well-being. 

    Clint explains how he discovered the power of grounding during his career in the cable television industry and how it led him to study its benefits on human health. From studies showing improved cortisol levels and reduced inflammation to anecdotes about athletes using grounding for recovery, this episode delves into the science and personal experiences that highlight the effectiveness of earthing. 

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    Timestamps and Highlights:  

    • 00:00:00 — Tour de France 

    • 00:00:30 — Dave Asprey’s Personal Journey with Grounding 

    • 00:02:00 — Welcome Clint Ober: The Grounding Pioneer 

    • 00:04:17 — Clint Ober’s Background and Discovery of Grounding 

    • 00:06:53 — The First Experiments and Observations 

    • 00:18:24 — Initial Studies and Surprising Results 

    • 00:25:54 — Collaboration with Dr. Stephen Sinatra 

    • 00:33:17 — Public Perception and Challenges 

    • 00:35:42 — The Organic Growth of Grounding 

    • 00:36:18 — David Wolfe and the Raw Vegan Movement 

    • 00:36:57 — The Impact of Grounding on Health 

    • 00:38:03 — Grounding in Sports: The Tour de France Story 

    • 00:40:12 — Scientific Evidence and Studies on Grounding 

    • 00:45:37 — Historical Practices of Grounding 

    • 00:48:47 — Grounding Products and Practical Tips 

    • 00:54:51 — The Future of Grounding Technology 

     • 01:05:36 — Final Thoughts and Encouragement 

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    24 September 2024, 10:00 am
  • 55 minutes 21 seconds
    Harnessing Quantum Energy: Unlocking the Power of Biofields and Consciousness : 1202

    In this episode of The Human Upgrade, we dive deep into the mystifying world of quantum energy with guest Philipp Samor von Holtzendorff-Fehling, founder of Leela Quantum Tech and Quantum Upgrade. Together with host Dave Asprey, Philipp unpacks the potential of harnessing quantum energy to enhance human performance, heal the body, and unlock higher consciousness.


    Philipp discusses how quantum energy has always existed and how modern technology now allows us to access and concentrate it like never before. From personal anecdotes involving quantum blocks to the exploration of biofields and how they influence everything from athletic performance to wound healing, this episode is packed with eye-opening insights.


    Dave shares his initial skepticism and eventual acceptance of quantum technology after experiencing the benefits firsthand. The conversation covers a range of fascinating topics including energy healing, distributed consciousness, quantum entanglement, and the ethics of working with energy fields. Plus, real-world examples like the flower experiment showcase the tangible effects of quantum energy in everyday life.


    Sponsors: 

    Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.

    Fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.


    Resources:


    Timestamps and Highlights:


    • 00:00:00 — Ancient Alien Technology?

    • 00:00:39 — Show Intro

    • 00:01:33 — Dave’s Experience with Quantum Technology

    • 00:04:45 — Introducing Philip Samor von Holtzendorf-Fehling

    • 00:05:38 — Quantum Technology Explained

    • 00:06:35 — Personal Experiences with Quantum Devices

    • 00:11:00 — Understanding Biofields and Energy Healing

    • 00:15:21 — Philip’s Journey to Quantum Technology

    • 00:21:22 — Quantum Energy in Sports Performance

    • 00:26:21 — Exploring Quantum Fields in Cells

    • 00:27:11 — Quantum Blocks and Distributed Consciousness

    • 00:27:53 — Quantum Energy and Flower Experiment

    • 00:28:36 — Leela Quantum and Quantum Upgrade Explained

    • 00:29:44 — Quantum Entanglement and Location

    • 00:32:00 — Energy Fields and Geomagnetics

    • 00:33:53 — Ethics and Integrity in Quantum Energy

    • 00:36:19 — Scientific Evidence and Blood Studies

    • 00:40:00 — Wound Healing and ATP Production

    • 00:41:47 — Autism Clinical Trials and Brainwave Analysis

    • 00:48:40 — Intuition and Frequency Selection

    • 00:54:17 — Final Thoughts and Call to Action


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    19 September 2024, 10:00 am
  • 1 hour 4 minutes
    3 Experts Reveal the Secrets to Optimizing Your Nutrition : 1201

    In this "Best of Nutrition" episode, 3 experts in nutrition share powerful insights on improving your health and performance through optimal eating habits. Listen in as Dr. Mark Hyman, Andrea Bemis, and Shawn Stevenson provide practical tips on boosting energy, improving digestion, and choosing nutrient-dense foods to help you feel your best. 

    Dr. Mark Hyman, a leading expert in functional medicine, dives deep into the importance of nutrient-dense foods and traditional cooking oils like ghee and olive oil. He shares his insights on how these healthy fats support brain health, metabolism, and overall well-being, especially in children. Learn how simple dietary changes can have a significant impact on health. 

    Shawn Stevenson, best-selling author and host of The Model Health Show, breaks down the role of nutrition in optimizing performance and mental clarity. He highlights the science behind choosing the right foods to fuel your body and mind, offering practical tips for enhancing energy and building a sustainable healthy lifestyle. 

    Andrea Bemis, author and advocate for regenerative agriculture, explores how the way we source and grow our food directly affects nutrient quality. She discusses the importance of eating seasonally and locally, providing valuable insights on how to incorporate farm-fresh foods into everyday meals to nourish your body and support the environment. 

    CHECK OUT THE FULL EPISODES NOW! 


    Sponsors:  

    Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.  

    ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. 


    Resources: 

     

    Timestamps and Highlights: 

    00:00:00 — Introduction by Dave Asprey 

    00:01:58 — Dr. Mark Hyman on Cooking Oils 

    00:04:04 — Feeding Kids Nutrient-Dense Meals 

    00:07:16 — Efficient Cooking and Eating with Kids 

    00:11:27 — Introducing New Foods to Children 

    00:12:56 — Listening to Kids’ Intuitive Eating Signals 

    00:14:28 — Salt in Children's Diets 

    00:22:32 — Regenerative Agriculture and Nutrient Density 

    00:31:28 — Finding High-Quality Foods 

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    17 September 2024, 10:00 am
  • 1 hour 1 minute
    3 Experts Reveal the Secrets to Gut Health : 1200

    In this episode of The Human Upgrade, gut health experts Dr. Steven Gundry, Dr. Edward Group, and Hannah Kleinfeld share groundbreaking insights into the gut microbiome, detoxification, and the impact of fermented foods on digestion. Discover how caring for your gut can enhance your energy, brain health, and immunity. 

    Check out the Full Episodes here:  

    Dr. Steven Gundry: https://youtu.be/SpO6k9Ofh2E 

    Hannah Kleinfeld: https://youtu.be/zFKHJIX8vtM 

    Dr. Edward Group: https://youtu.be/GV2KnL0wW9M 

    Sponsors: 


    Resources: 

     

    Timestamps and Highlights: 

    • 00:01:00 — Introduction to Gut Health and Parasites with Dr. Steven Gundry 
    • 00:06:00 — Fermented Foods & Gut Health with Hannah Kleinfeld 
    • 00:12:30 — Probiotics and Detox with Dr. Edward Group 
    • 00:18:00 — Practical Steps for a Healthier Gut 


    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    12 September 2024, 10:00 am
  • 1 hour 2 minutes
    Natural Ways to Prevent Alzheimer's and Boost Brain Health with Dr. Heather Sandison : 1199

    In this episode of The Human Upgrade, Dave Asprey and Dr. Heather Sandison discuss actionable strategies for optimizing brain health and longevity. Dr. Sandison explains how lifestyle changes, including diet, oral hygiene, and sleep, can help prevent cognitive decline. She also shares insights into the Marama Experience, her revolutionary approach to memory recovery and brain health. 

    Sponsors:  

    Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.  

    Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. 


    Resources: 

     

    Timestamps and Highlights: 

    00:00:01 – Introduction by Dave Asprey 

    00:02:30 – The Role of Diet in Brain Health 

    00:07:00 – The Importance of Oral Health in Brain Function 

    00:12:00 – How Sleep Impacts Cognitive Health 

    00:17:30 – Key Strategies for Optimizing Cognitive Function 

    00:22:00 – The Marama Experience: Memory Care to Memory Recovery 

    00:30:00 – Steps for Protecting Brain Health Over Time 

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    10 September 2024, 10:00 am
  • 41 minutes 7 seconds
    The Cognitive Power of AmaTea® Max for Sustainable Energy & Mental Clarity : 1198

    In this episode of The Human Upgrade, Dave Asprey talks to Chris Fields, Chief Science Officer at Applied Food Sciences, about the game-changing nootropic AmaTea® Max. They discuss how this natural extract of guayusa delivers long-lasting energy and mental clarity, backed by science and sustainable practices. Learn how AmaTea® Max is revolutionizing cognitive performance, especially for athletes and gamers. 

    Resources: 

     

    Timestamps and Highlights: 

    00:01 – Why Caffeine is a Super-Powerful Nootropic 

    04:00 – The Science of Guayusa and AmaTea® Max 

    07:00 – Cultural Roots and Sustainable Sourcing 

    11:30 – The Cognitive Benefits of AmaTea® Max 

    16:20 – How AmaTea® Max Differs from Traditional Caffeine Sources 

    20:00 – Applications in Gaming and Sports 

    25:00 – Sustainability and Social Impact 

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    6 September 2024, 10:00 am
  • 1 hour 2 minutes
    Rewiring Your Brain for Hope: How to Overcome Cynicism with Dr. Jamil Zaki : 1197

    In this episode of The Human Upgrade, Dave Asprey welcomes Dr. Jamil Zaki, a professor of psychology at Stanford University and the director of the Stanford Social Neuroscience Lab. Dr. Zaki discusses the critical intersection between empathy, cynicism, and hope, exploring the impacts of negativity bias, cynicism in modern society, and how we can rewire our brains to become more hopeful. Drawing from his latest research and new book, Hope for Cynics, Dr. Zaki shares profound insights on human goodness, how we can challenge our biases, and the practices that can help us foster a more positive outlook on the world. 

    Sponsors: 

    • Puori | Visit https://puori.com/dave and use code DAVE for 20% storewide.  
    • ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.   


    Resources: 

     

    Timestamps and Highlights: 

    • 00:00:01 – Introduction by Dave Asprey 
    • 00:02:00 – Dr. Zaki on Cynicism and Empathy 
    • 00:05:30 – The Science Behind Empathy and Human Goodness 
    • 00:10:00 – The Impact of Negativity Bias on Decision-Making 
    • 00:15:00 – How to Overcome Cynicism Through Skepticism 
    • 00:20:30 – Practices to Foster Empathy and Optimism 
    • 00:30:00 – Understanding Cynicism in the Digital Age 
    • 00:35:00 – Building Hope in Relationships and Society 


    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    5 September 2024, 10:00 am
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