In this inspiring and far-reaching conversation, Joe Moore is joined by Vince Kadlubek, the founder and Chief Visionary Officer of Meow Wolf, the groundbreaking arts and entertainment company known for its massive, immersive art experiences. Together, they dive deep into Meow Wolf’s humble DIY origins, its evolution into a multi-city creative juggernaut, and how it intertwines with psychedelic culture and expanded states of consciousness.

Vince shares the story of Meow Wolf’s formation in Santa Fe, the evolution from a group of passionate friends into a thousand-person company, and the power of belief, creativity, and visionary leadership. He reflects on raising funding from George R. R. Martin and major investors, navigating massive growth, and the challenge of keeping the creative spark alive in the face of institutionalization.

They also discuss the upcoming Bicycle Day Portal Takeover at Meow Wolf Denver on April 19, which will feature performances, talks, and immersive experiences throughout the exhibition—with appearances from Reggie Watts, Duncan Trussell, Zach Leary, and more.

From the imaginative to the esoteric, Vince and Joe explore the intersection of psychedelics and art, the nature of reality and the imaginal realm, and how to build beauty and wonder into the world around us.

🌀 Topics Covered

• What Meow Wolf is and how it all began
• Growing from a DIY collective to a nationwide phenomenon
• Maintaining creative spirit through growth and structure
• Vision, belief, and the spiritual work of creating art
• Navigating private equity and big funding in the arts
• Santa Fe’s unique cultural and energetic imprint
• Portal’s Bicycle Day event at Meow Wolf Denver
• Fictional character sentience and AI in immersive worlds
• Art as a cultural response in times of uncertainty
• Psychedelics as tools for accessing the imaginal and creative realms

Bicycle Day at Meow Wolf Denver – April 19

Hosted by Portal, this one-of-a-kind immersive celebration of Bicycle Day takes over the entire Meow Wolf Denver space. Expect DJs, speakers, psychedelic storytelling, ecstatic dance, art, and surprises around every corner.

Featured Guests Include:

• Reggie Watts
• Duncan Trussell
• LP GIOBI (Dead House)
• Zach Leary
• David Satori (Dirtwire)
• Frick Frack Blackjack
• Dennis Walker
• Veronica Lightning Horse Perez
• …and many more to be announced!

🌀 Plus: Pre-event Bicycle Day bike ride through Denver, curated by Portal.

📍 More Info

• Learn more about Meow Wolf
•  
• Check out Portal Events for Bicycle Day details

📣 Support the Show

If you love what we do, please share this episode, leave a review, and consider supporting us in our Navigators Program.

In this episode, Joe interviews Fayzan Rab, an MD candidate (when we recorded) at Emory University with a background in tech at Google and a focus on the intersection of psychedelics, spirituality, and public health. Fayzan shares Emory’s unique approach to psychedelic studies, emphasizing spiritual health and the lived religious and existential aspects of psychedelic experiences—what he and his team call “CERT.”

The conversation explores Fayzan’s collaboration with health economist Elliot Marseille on economic modeling for psilocybin therapy, including their estimate that over 5 million Americans could be medically eligible. He shares insights into the policy challenges around payer systems and the importance of preparing implementation strategies before FDA approval.

Fayzan also discusses his groundbreaking research on Muslim perspectives on psychedelics—revealing surprising openness, complex spiritual tensions, and a strong interest in integrating these substances into healing and faith-based frameworks. He highlights the need for inclusive infrastructure and upcoming work with clergy to deepen the conversation.

Finally, they explore non-clinical psychedelic use among healthcare workers and entrepreneurs, discussing how psychedelics are being used to address burnout, identity, and life purpose.

This is a powerful episode about interdisciplinary collaboration, cultural sensitivity, and the potential for psychedelics to transform not just individuals—but systems.

Links

Science on Spiritual Health Symposium 2025

Center for Psychedelics and Spirituality - Emory University

In this episode of Psychedelics Today, Kyle Buller is joined by Dr. Hannah McLane, founder of the SoundMind Center and SoundMind Institute. They dive deep into the evolving psychedelic landscape—touching on policy developments in New Jersey, Massachusetts, Pennsylvania, and beyond. Dr. McLane shares her experience testifying in support of psilocybin legislation and discusses the medical frameworks being explored, particularly in contrast to Oregon and Colorado’s models.

The conversation also explores the essential qualities of effective psychedelic facilitators, emphasizing the importance of self-awareness, lifelong learning, and doing personal inner work. Dr. McLane offers insights into the challenges of entrepreneurship in the psychedelic space, balancing mission-driven work with sustainability, and how neurodiversity and trauma have shaped her approach.

Toward the end, the conversation takes a playful and heartfelt turn, reflecting on parenting, the power of curiosity, and the need for more community-centered, human-first spaces for integration and healing. This is a rich, honest, and inspiring dialogue that bridges the personal and political, the clinical and ceremonial, and the visionary future of psychedelics.

In this powerful episode of Psychedelics Today, we sit down with the team behind Natural Medicine Alaska to discuss their groundbreaking efforts to bring psychedelic reform to the state. With some of the highest rates of depression, suicide, and substance use disorders in the nation, Alaska stands at a pivotal moment in the movement for mental health transformation.

Joe Moore speaks with Gina, President of Natural Medicine Alaska; David Aloff, an Alaska Native advocate; and Noria Clark, Veterans Coordinator to explore the origins of their movement, the importance of traditional healing protections, and their 2026 ballot initiative to decriminalize plant medicines and establish a regulated therapeutic model.

The discussion dives into:

• The personal journeys that led each guest to this work

• How Alaska’s libertarian spirit aligns with psychedelic reform

• The push to make Alaska the first state to include Ibogaine clinics in legislation

• The urgent need for veteran and first responder access to psychedelic therapy

• Fundraising and grassroots efforts to get the initiative on the ballot

• The role of Alaska’s natural landscape in healing and psychedelic integration

With national psychedelic policy at a crossroads, Alaska has the opportunity to become the North Star of this movement. Listen in to learn how you can support this critical campaign!

Support Natural Medicine Alaska: 💰 Donate: NaturalMedicineAlaska.org 📢 Share this episode to raise awareness! 📅 Attend Arctic Visions Psychedelic Conference in August 2025: arcticvisions.com

🎧 Listen & Subscribe: Available on Spotify, Apple Podcasts, and all major platforms.

Podcast Show Notes: Psychedelics, Harm Reduction & Ethical Care with Erica Siegal

In this episode of Psychedelics Today, Joe Moore sits down with Erica Siegal, founder of Nest Harm Reduction and Shine Collective, for a deep conversation on psychedelic harm reduction, ethical facilitation, and the evolving psychedelic landscape. Erica shares her journey from the Grateful Dead lot scene to festival harm reduction, social work, and leading initiatives to support survivors of psychedelic-related harm.

The conversation covers:

• Erica’s background in hospitality, social work, and psychedelic harm reduction
• The mission of Nest Harm Reduction in offering psychedelic therapy, integration, and community education
• The work of Shine Collective, a nonprofit supporting survivors of psychedelic harm and abuse
• The challenges of ethical facilitation, power dynamics, and the importance of clear boundaries
• How the psychedelic community can better address harm, accountability, and survivor support
• The intersection of Jewish spiritual traditions and psychedelics through Shefa

This episode is a must-listen for those passionate about harm reduction, ethical psychedelic practice, and building a safer, more accountable psychedelic culture.

Army Ranger to consultant to leading one of the most respected psychedelic retreat organizations, detailing how meditation and psychedelic therapy helped him heal from trauma.

The conversation covers:

• Neal’s military background and his path to psychedelics
• The mission and structure of Beckley Retreats, an offshoot of the Beckley Foundation
• How their retreats integrate meditation, preparation, and integration for long-lasting benefits
• The legal landscape of psilocybin in Jamaica and the Netherlands
• Challenges and lessons from running a psychedelic retreat business
• The future of psychedelics, from global access to potential federal policy shifts

Whether you're curious about immersive psychedelic retreats, the intersection of mental health and psychedelics, or the evolving legal landscape, this episode is packed with insight.

Learn more about Beckley Retreats here.

Hear more from Neil on Psychedelics Today here.

In this episode, Joe Moore of Psychedelics Today sits down with Paul Austin, founder of The Third Wave, to dive deep into the evolution of microdosing and its growing role in psychedelic culture. Paul shares how his journey with microdosing LSD led him to launch The Third Wave in 2015 to make psychedelics more accessible through education. The conversation explores the latest research on microdosing, including clinical trials demonstrating its potential benefits for depression, mental clarity, and creativity. Paul and Joe discuss the nuances of different microdosing protocols, the role of psychedelics in performance optimization, and the impact of these substances on neuroplasticity. They also tackle key challenges, such as the lack of robust clinical research due to regulatory hurdles and the perceived risks associated with overuse. Beyond microdosing, they touch on the broader psychedelic landscape—regulatory shifts, emerging coaching models, and the future of psychedelic-assisted transformation. The discussion even ventures into intriguing intersections between psychedelics, AI, and the possibility of extraterrestrial intelligence. Tune in for a thought-provoking conversation on where microdosing fits into the larger psychedelic resurgence.

In this episode of Psychedelics Today, Joe Moore sits down with Louis Dorian, the visionary behind Psychedelist, a groundbreaking global platform designed to support the emerging psychedelic movement. Described as a “cyber city” for all things psychedelic, Psychedelist connects individuals with treatment providers, educators, facilitators, legal experts, and even vetted product vendors in an effort to enhance accessibility and safety in this evolving space.

Louis shares his journey into psychedelics, from early rave days to a transformative encounter with high-dose LSD and psilocybin that shaped his worldview. He opens up about the struggles of navigating trauma, loss, and the shortcomings of Western psychiatric care, leading him to develop his own trauma-processing techniques blending meditation, breathwork, and psychedelics.

The conversation also dives deep into the broader implications of drug prohibition, harm reduction, and the role of skill-building in responsible psychedelic use. Whether you're a seeker, a skeptic, or a professional in the field, this episode offers a compelling exploration of the psychedelic landscape and the power of intentional community building.

Resources:

• Visit Psychedelist
• Follow Louis Dorian on Instagram: @psychedelist
• More from Psychedelics Today: Website

Tune in for an eye-opening discussion on the future of psychedelics, regulation, and self-exploration!

In this episode of Psychedelics Today, Joe Moore is joined by Neeka Levy and Zach Skiles of Heal Ukraine Trauma, a nonprofit bringing psychedelic-assisted therapy to veterans and civilians affected by war. They discuss the organization’s origins, the impact of intergenerational trauma in Ukraine, and the evolving role of psychedelic treatments in a war-torn nation.

Nika, a first-generation Ukrainian-American and neuroscience-trained psychiatric nurse practitioner, and Zach, a Marine veteran turned psychologist, share their journey into this work, highlighting the importance of group ketamine therapy as a scalable, culturally aligned solution. They explore Ukraine’s complex regulatory landscape, the need for rigorous research, and the challenges of working in a war zone.

They also touch on the role of psychedelics in processing moral injury, the importance of including family members in healing, and how Ukraine’s collectivist culture influences therapeutic approaches. With insights on historical trauma, ethical considerations, and the potential future of MDMA and psilocybin therapy in Ukraine, this conversation sheds light on a vital, evolving effort.

In this episode, Joe interviews Josh Lipson, a Ph.D. candidate in clinical psychology at Columbia University, whose research explores the relationship between psychedelics, mystical experiences, and mental health.

He discusses the complexities of studying psychedelics in real-world settings, the role of metaphysical perspectives in research, and why different individuals respond to psychedelics in such varied ways. Lipson shares his personal journey into psychedelic research, the challenges of interdepartmental collaboration, and the evolving landscape of modern psychedelic science.

He also talks about:

• The importance of integration after psychedelic experience
• Why mystical experiences may not be the only path to healin
• The balance between stability and the chaos psychedelics can introduc
• The need for diverse perspectives and ways of knowing in psychedelic researc
• How psychedelics have shaped global consciousness and cultural perspectives

and more!

For links, head to the show notes page.

In this episode, Joe interviews Nico and Susan Simon: Co-founders of JourneyŌM, a concierge service looking to address the question many people are asking: How do you find the right facilitator?

Through a dedicated vetting process, JourneyŌM is adding a layer of risk reduction and accountability to this strange new world, by traveling the country and amassing a network of trusted facilitators who work with all types of medicines and modalities. By getting to know guides and seekers personally, they’re able to offer possible matches – and they usually agree on who would work best with each other.

They talk about:

• Their process for building their network and finding the right facilitator for someone
• Their concept of going “beyond the bio” and getting to the heart of what drove someone toward becoming a guide
• Susan’s struggle with supporting Nico through his psychedelic healing, and the need for support options for spouses not sharing in the experience
• The importance of community and the amazing work Nico has seen in men’s groups
• The healing powers of movement and living as your authentic self

and more!

If you’re interested in JourneyŌM’s matchmaking, head to their site and take their assessment to begin the process.

For links, head to the show notes page.