Health psychologist Dr. Kari Leibowitz traveled to some of the coldest, darkest places on earth to learn how people there don’t just survive, but thrive in winter. She says that one of the key ingredients is adopting a positive wintertime mindset by focusing on and celebrating the good parts of winter.

Flora Lichtman talks with Dr. Kari Leibowitz, author of How to Winter: Harness Your Mindset to Thrive on Cold, Dark, or Difficult Days, about saunas, cold plunges, candles, and other small ways to make winter a season to look forward to rather than dread. Plus, she responds to some of our audience’s own tips to make the season enjoyable.

What Would You Call The Fun Parts Of Winter?

Do you think “winter doldrums” needs a positive rebrand? Let us know what you would call the winter experience instead by leaving us a voicemail at 1-646-767-6532.

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Birds are the master vocalists of the animal kingdom. They can make a remarkable variety of sounds.

But why is a barred owl more of a baritone, while a cedar waxwing is a soprano?

And what influences a bird’s vocal range, and the kinds of sounds it can make? Beak size? Body size? Geography?

To answer some of these questions, researchers analyzed over 140,000 bird vocalizations from all over the world to try to peck out some kernels of knowledge about bird calls and songs. Their research was recently published in Proceedings of the Royal Society B.

Flora Lichtman talks with Dr. Zuzana Burivalova, assistant professor of forest & wildlife ecology at the University of Wisconsin-Madison about her latest research.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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It’s been five years since the first laboratory-confirmed case of COVID-19 in the U.S., a bleak milestone in the early days of a pandemic that touched the lives of everyone. For the lucky ones, the virus mainly meant more precautions: mask-wearing, the occasional COVID test. But for others, a COVID-19 infection turned into long COVID. This is a chronic condition that lingers long after a COVID infection, and can reduce one’s ability to live their day-to-day life.

It’s been estimated that about 400 million people worldwide have had long COVID. Some researchers say that number is much higher. But there’s a lack of research on successful treatments for long COVID.

Some patients living with the condition have taken things into their own hands. A recent investigation documented the experiences of 13 long COVID patients who tried taking Paxlovid for longer than the typical 5-day course. The patients had mixed results, adding to a growing body of evidence that there will not be one silver bullet for treating the condition.

Joining Ira to talk about the results are two authors of the study, who have both had long COVID for years: Dr. Alison Cohen, assistant professor of epidemiology and biostatistics at the University of California San Francisco, and Dr. Julia Moore Vogel, senior program director at Scripps Research in La Jolla, California.

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A recent study in the journal Nature unveiled new proteins that can neutralize the deadliest of snake venoms. They’re “new” in that they aren’t found in nature—they were created in a lab, dreamed up by AI.

Using AI to discover, or design, the building blocks of drugs is a fast-growing area of research. Another team of scientists out of Philadelphia is using AI to discover new antibiotics by resurrecting long-lost molecules from extinct species like neanderthals and woolly mammoths.

We know what you’re thinking: It sounds too sci-fi to be true.

Flora Lichtman talks with two pioneers in the field about how AI is supercharging drug discovery: Dr. César de la Fuente, bioengineer and presidential associate professor at the University of Pennsylvania in Philadelphia, and Nobel laureate Dr. David Baker, director of the Institute for Protein Design and professor at the University of Washington in Seattle.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

For our Los Angeles listeners: We’re working on a story about the toxins left behind by the fires and we want to hear from you. How is this affecting you? Are you worried about the air and water and soil? How are you approaching clean-up? And what questions do you have?

Leave us a voicemail at 1-646-767-6532 or send us an email at [email protected].

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Researchers at the National Institutes of Health say the move has sent fear and confusion throughout the agency. Plus, what's the technology behind meme coins?

Trump Administration Cancels Meetings, Freezes Hiring At NIH

This was President Trump’s first week back in the Oval Office. Along with issuing a flurry of executive orders, his administration has imposed a range of restrictions on the National Institutes of Health, affecting meetings, travel, hiring, funding, and communications. Scientists expressed alarm about what this could mean for ongoing research, with no clear timeline for if or when the freeze would be lifted.

Flora Lichtman is joined by Casey Crownhart, climate editor at the MIT Technology Review, to catch up on this and other big science stories of the week, including what’s coming next this year for nuclear power, why a record amount of snow fell in the Southeast this week, and new research on the surprisingly complex biology of a manta ray tail.

What Exactly Is A Meme Coin And How Does It Work?

A few days before President Trump’s inauguration, he hosted a “crypto ball” in Washington, D.C. That night, he unveiled his very own meme coin—a kind of digital asset that has gained a reputation for facilitating scams. Soon after, first lady Melania Trump also launched her own meme coin. After its launch, Trump’s coin’s market capitalization reached billions of dollars.

This isn’t the first time meme coins have gotten a lot of attention—you might remember Elon Musk joked about another one called Dogecoin on SNL in 2021—but it is the first time that this technology has been used by a sitting president. So what exactly is a meme coin anyway? How does the blockchain play into all this? And how might a president use it differently than an internet celebrity?

To find out more, Flora Lichtman talks with Liz Lopatto, a senior writer at The Verge who covers cryptocurrency and business, about how this market started, how Trump could use meme coins, and where the crypto market could go next.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Editors at scientific journals are quitting in droves. According to Retraction Watch, a watchdog publication, there have been at least 20 mass resignations since 2023.

So, what’s going on? If you look closely, you’ll notice a common pattern—publishers are cutting back on the number of editors, increasing the number of papers, and charging hefty fees for authors to publish their work.

The most recent mass resignation happened at the Journal of Human Evolution at the end of 2024. Both co-editors in chief and the entire editorial board quit, except for one person.

What does this mean for the future of scientific publishing? Have these resignations made the big publishers change their ways? Is the strict academic publishing system we know in danger?

To answer those questions and more, Ira talks with Dr. Andrea Taylor, former co-editor in chief of the Journal of Human Evolution; and Ivan Oransky, co-founder of Retraction Watch and editor in chief of The Transmitter.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Rejoice, amateur and professional astronomers: This January is a fantastic time for looking up at the sky.

The flashiest event of the season is also one of the easiest to see without binoculars or a telescope. A “parade of planets”—Venus, Saturn, Jupiter, and Mars—will be visible, and recognizable by their incredible brightness against the night sky. Uranus and Neptune will also be visible, but with a telescope. This string of planets will be visible for all of January.

Additionally, the ATLAS comet, discovered last year by NASA’s Asteroid Terrestrial-impact Last Alert System, has come close enough to the sun—8.3 million miles away—to be visible with binoculars or a telescope. Be careful, though: looking at sunrise or sunset could hurt your eyes.

Astronomer Dean Regas, host of the podcast “Looking Up with Dean Regas,” joins Ira from Cincinnati, Ohio, to discuss the best things the winter night sky has to offer this year, with or without a telescope.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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From down here on Earth, life on the International Space Station seems magnificent: floating through the day, enjoying stunning views out your window, having an experience only a handful of other people will ever get.

But what’s it really like to live up there? How does experiencing 16 sunrises and 16 sunsets every day change your perception of time? How do you cope with being so far from the people you love?

Those are some of the questions explored in the novel Orbital, which won the Booker Prize late last year. In the book, author Samantha Harvey imagines the inner life of astronauts aboard the ISS.

Host Flora Lichtman is joined by Samantha Harvey, along with astronaut Dr. Cady Coleman, who spent almost six months on the Space Station, and is an author herself. They talk about the unexpected mundanities of living in space, how Harvey was inspired to write the book during lockdown, and how astronauts make sense of their new reality when separated from the rest of humanity.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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Since January 7, wildfires have been devastating the Los Angeles area. In the span of 10 days, several different fires, including the Palisades and Eaton fires, have burned more than 40,000 acres and destroyed more than 12,000 structures. At least 25 people have died.

The threat of fire is growing, especially in zones known as the wildland-urban interface, or WUI. That’s where unoccupied wildland and human developments meet and mingle. Think of a city sprawling around a forest, for example. In the US, around one in three homes is in this type of high-risk zone.

So what’s the science behind urban fires? And how do we protect ourselves in the face of them?

Ira Flatow talks with Dr. Kimiko Barrett, senior wildfire researcher and policy analyst at the research group Headwaters Economics in Bozeman, Montana; and Dr. Alexandra Syphard, senior research scientist at the Conservation Biology Institute in San Diego, California.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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The SpaceX rocket carries lunar landers from companies based in Texas and Japan. They could arrive at the moon in the coming months. HPV can cause a variety of cancers, including cervical. New mortality data for women under 25 point to the success of the HPV vaccine.

Rocket Launches With Lunar Landers From 2 Private Companies

On Wednesday, a SpaceX rocket launched carrying payloads from two separate private companies hoping to achieve lunar landings. The pair of landers—one from Japanese company ispace, and one from Texas-based Firefly Aerospace—will take months to reach the moon. Firefly’s lander is scheduled to arrive first, in March, with ispace’s lander planned for a touchdown in late May or early June.

Another SpaceX launch on Thursday, a test flight of the company’s Starship system, had mixed results. The booster returned to earth and was successfully “caught,” but the spacecraft exploded over the Caribbean shortly after launch. That explosion is under investigation.

Jason Dinh, climate editor at Atmos in Washington, D.C., joins Ira to talk about the Wednesday launch and plans for private lunar exploration. They also discuss other stories from the week in science, including the ban of Red Dye #3 an AI approach to snake antivenom, and a study predicting a rise in US dementia cases by 2060.

As Cervical Cancer Deaths Plummet, Experts Credit HPV Vaccine

In 2006, a vaccine for the human papillomavirus (HPV) became widely available to adolescents. HPV is the most common sexually transmitted infection, and it can cause cancers of the mouth, throat, and sexual organs. It’s also the cause of nearly every case of cervical cancer.

Now, almost 20 years after the HPV vaccine was introduced, a study published in JAMA noted a 62% drop in deaths due to cervical cancer in women under 25 in the US: from 50 or 60 deaths per year to 13. This follows earlier research that noted a decrease in cervical precancer and cancer since the introduction of the vaccine.

With HPV vaccine uptake at about 60% for adolescents aged 13-15, a higher uptake could virtually eliminate cervical cancer, experts say. However, childhood vaccination rates have dwindled since the start of the COVID-19 pandemic, sparking concerns about the spread of preventable disease.

Joining Flora Lichtman to talk about this latest study is lead author Dr. Ashish Deshmukh, professor of public health sciences and co-leader of the Cancer Prevention and Control Program at the Medical University of South Carolina in Charleston, South Carolina.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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For years, artificial intelligence companies have heralded the coming of artificial general intelligence, or AGI. OpenAI, which makes the chatbot ChatGPT, has said that their founding goal was to build AGI that “benefits all of humanity” and “gives everyone incredible new capabilities.”

Google DeepMind cofounder Dr. Demis Hassabis has described AGI as a system that “should be able to do pretty much any cognitive task that humans can do.” Last year, OpenAI CEO Sam Altman said AGI will arrive sooner than expected, but that it would matter much less than people think. And earlier this week, Altman said in a blog post that the company knows how to build AGI as we’ve “traditionally understood it.”

But what is artificial general intelligence supposed to be, anyway?

Ira Flatow is joined by Dr. Melanie Mitchell, a professor at Santa Fe University who studies cognition in artificial intelligence and machine systems. They talk about the history of AGI, how biologists study animal intelligence, and what could come next in the field.

Transcripts for each segment will be available after the show airs on sciencefriday.com.

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