President-elect Donald Trump says he plans to nominate former TV host Dr. Mehmet Oz to lead the Centers for Medicare and Medicaid Services. The agency oversees insurance programs covering more than 150 million Americans. Julie Rovner of KFF News breaks down Dr. Oz's views on health care. Then, the ACLU filed a lawsuit this week against ICE, seeking more information about how it might carry out large-scale deportations in the incoming Trump administration. The ACLU's Eunice Cho joins us. And, comedian, actor and author Jenny Slate recently released "Lifeform," a new collection of essays about life, love and having a child. Here & Now's Emiko Tamagawa speaks with Slate.

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Ukraine fired U.S-supplied long-range missiles into Russia for the first time, a U.S. official confirmed to NPR. Washington Post chief Ukraine correspondent Siobhán O'Grady joins us to break down what the development means and look back at 1,000 days of war in Ukraine. And, the Department of Justice is set to take another crack at breaking up what it perceives to be a monopoly held by Google's parent company Alphabet. Roben Farzad, host of the podcast "Full Disclosure," explains the ideas being considered. Then, popular video game company Roblox says it is taking new steps to keep children safe after a financial research firm labeled the platform a "pedophile hellscape." Roblox chief safety officer Matt Kaufman explains what he thinks those changes will accomplish.

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President-elect Donald Trump has tapped wealthy entrepreneurs Elon Musk and Vivek Ramaswamy to cut the federal budget. But just how much waste is there to trim? The Brookings Institution's Elaine Kamarck explains. Then, Tracey Danka voted for Trump. But her husband Ed Danka voted for Kamala Harris. The couple discusses how they get along, despite their political disagreements. And, Robert F. Kennedy, Jr. has called for an end to the practice of putting fluoride in water. University of Iowa's Steven Levy takes a closer look at what that would mean for dental health.

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We look at President-elect Donald Trump's picks for his incoming administration and what's expected from the next Republican-controlled Congress with USA Today's Francesa Chambers and NBC's Scott Wong. And, a jury found the Virginia-based contractor CACI liable for "conspiring with" U.S. soldiers to "inflict torture" at Abu Ghraib prison in Iraq. We take a look at the decision with The New York Times' Mattathias Schwartz. Then, Sy Montgomery, author of the bestselling "The Soul of an Octopus," talks with us about her new book, "What the Chicken Knows," which explores the extraordinary individuality and intelligence of the ordinary fowl.

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We break down President-elect Donald Trump's controversial nomination of former Rep. Matt Gaetz for Attorney General with Marc Caputo, national political reporter with the Bulkwark. And, clinical psychologist Dr. Ramani Durvasula joins us to discuss how to cope with narcissistic people. Then, we look into the future of U.S.-Israel relations with Aaron David Miller, senior fellow at the Carnegie Endowment for International Peace.

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President-elect Donald Trump has picked former Arkansas Gov. Mike Huckabee to serve as his ambassador to Israel. The Washington Post's John Hudson explains what this could mean for U.S. policy. And, Trump has pledged to deport millions of undocumented people during his next administration. Pew Research Center's Jeff Passel breaks down what that could mean for the industries that employ them. Then, we remember jazz legend Roy Haynes who died on Tuesday.

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President-elect Donald Trump has vowed to cut federal jobs, move positions out of the Washington metro area and eliminate the federal Department of Education. The Washington Post's Lisa Rein explains the impact of these promises. And, the CEO of oil giant ExxonMobil wants President Trump to rethink his promise to pull the U.S. out of the Paris climate agreement. Full Disclosure host Roben Farzad explains why. Then, schools across the U.S. are replacing their asphalt playgrounds with trees and shade structures. Danielle Denk from the Trust for Public Land explains how this benefits everyone.

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How might Russia's war on Ukraine change after President-elect Trump takes office? NPR's Joanna Kakissis explains. Then, Here & Now's Karyn Miller-Medzon brings us to a Boston hospital that is helping Ukrainian doctors rebuild their country's decimated health care system. And, President-elect Donald Trump has promised to place tariffs on goods from China. Scott Kennedy of the Center for Strategic and International Studies joins us to explain what that could mean for consumers. Then, a new artificial intelligence-fueled platform called Fight Health Insurance helps people generate appeals to denied health insurance claims. Holden Karau, the site's creator, joins us to explain how it works.

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Global climate talks begin next week. How will the incoming administration of President-elect Donald Trump affect them? Attracta Mooney of The Financial Times explains the environmental implications of his win. And, Democratic strategist David Axelrod breaks down what lessons the Democrats can learn from Trump's victory. Then, a new study found that a group of bacteria in wastewater can break down PFASs or forever chemicals. Northwestern University chemist William Dichtel joins us to discuss what the discovery means.

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President-elect Donald Trump made significant gains among Latino communities during the 2024 election. MSNBC contributor Julio Ricardo Varela explains why. And, Trump will face multiple foreign policy challenges in his second term. NPR's Emily Feng in Beijing, Daniel Estrin in Tel Aviv, Charles Maynes in Tblisi, Georgia, and Eyder Peralta in Mexico City join us. Then, forget about the Red Delicious. We are living in a golden age of apples with more than 20 different varieties available at grocery stores. David Bedford, an apple researcher at the University of Minnesota, joins us.

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Former President Donald Trump will return to the White House next year. The Washington Post's Michael Scherer explains how Trump won. Then, Jacorie McCall is a Black voter who supports Trump and has worked on past Republican campaigns. He reacts to the victory. And, Axios' Margaret Talev takes a look at Trump's likely policies on issues ranging from immigration to health care to taxes and foreign policy. Plus, Here & Now's Peter O'Dowd reports from Arizona. Finally, former Pennsylvania Rep. Jim Greenwood, co-founder of Pennsylvania Republicans for Harris-Walz, talks about which political messages did and didn't resonate in the battleground state.

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