A hard-hitting exposé of how methadone clinics fail people in recovery—and an urgent, unapologetic case for their abolition. 

Methadone is a life-saving medication. But the current system for obtaining it—the opioid treatment program, commonly known as the methadone clinic—is punitive, unjust, and often humiliating. In this eye-opening book Liquid Handcuffs: Policing and Punishment in Methadone Clinics and the Future of Opioid Addiction Treatment (North Atlantic Books, 2026), social worker and journalist Helen Redmond takes readers inside the hidden world of methadone clinics, exposing the “culture of cruelty” that polices, punishes, and profits from those they’re meant to serve. Through patient stories and extensive interviews with methadone users and clinic workers, Redmond weaves a compelling argument against the current clinic system. She provides a detailed history of how methadone was first developed and why the current system for dispensing methadone arose in the U.S., tracing its entanglement with the carceral system and the “War on Drugs” as well as private equity firms and tech companies. She details the numerous barriers to enter and remain and treatment, as well as standard practices that shame and discriminate against patients, such as restrictions on take-home doses; daily attendance requirements; regular urine testing; and threats of cutting off medication for any infraction of clinic rules. She also explores the nuances of resistance to methadone clinics within communities of color, unpacking the political, racial, and cultural circumstances behind the opposition to methadone. Redmond persuasively makes the case for removing police agencies like the DEA from clinic administration, and shows how a transition to provider-prescribed pharmacy pickup, along with other tools of harm reduction such as safe-supply and peer-support services, would restore dignity to patients struggling with addiction—and save thousands of lives.

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Neuroscientific evidence increasingly shows that consciousness is a remarkable but explainable function of a machinelike brain. Alan J. McComas' discusses his article for the American Scientist.

Alan J. McComas is an emeritus professor of medicine at McMaster University in Hamilton, Canada.

Greg is the Executive Director and Founder of the World War II Discussion Forum (wwiidf.org). He also has a strong interest in literature, culture, religion, science and philosophy (translation: he's an eclectic reader who is constantly missing deadlines for book reviews).

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In this conversation we hear about Kola’s journey as self-taught coder, business school, learning by doing, and how he is self-funding one person AI company for doctors: Kola Tytler’s parallel journey as an NHS Doctor while building pioneering and potentially world changing business is inspiring.

Listen in on a remarkable conversation between host Richard Lucas and Kola Tytler, now a qualified doctor who taught himself to code.

We explore

• the roots of his entrepreneurial activity, despite knowing he wanted to be a doctor from a young age.

• the influence and opportunities of being an immigrant from a different background as he went to medical school in London.

• his first venture selling event tickets via a Facebook platform, scaling a fashion blog with millions of followers, and launching and exiting the successful Dropout retail business in Milan

• Lessons of having investors who were not always aligned

• How he dealt with realising that he might have a bigger financial opportunity through dropping out of his studies.

• The benefits and limitations of bootstrapping when you have the resources to put together a great team

• The impact of both his formal business school education and self tuition via online resources like Y Combinator, and prominent SV figures like Steve Jobs and Bill Gates.

• The ambition and vision for his self funded AI platform for doctors iatroX which provides clinical guidance to over 20,000 users.

Kola's journey is a masterclass in calculated risk and relentless drive, Kola shares the critical lessons he has learned from his triumphs and challenges. Through insightful questions, Richard draws out the key takeaways on finding balance, the importance of a strong team, understanding domain expertise, and the necessity of continuous business education. This episode is packed with inspiration for anyone looking to bridge diverse passions and build a high-impact venture.

About Kola

Dr Kola Tytler – Doctor/MBA & full-stack developer

MBBS @ King’s College London

Certificates in Law & Business (LSE & Imperial)

MBA (with merit) @ University of Birmingham

MSt Entrepreneurship @ University of Cambridge ‘26

Forbes 30 under 30 Europe, Forbes 100 under 30 Italy

IBM-certified AI Engineer & MENSA member

Founder of YEEZY Mafia, dropout, & HypeAnalyzer

Links

iatroX is a UKCA-marked, MHRA-registered medical device. It acts as an AI‑driven assistant that centralizes clinical guidelines offering: 1 quick Q&A, 2 structured brainstorming, and 3 an adaptive quiz engine for medical students.

Kola Tytler's Linkedin

Kola Tytler's personal website
Drop Out Milano
Hype Analyzer

CAMentrepreneurs

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Dr. Hanna Pickard has written a revolutionary new paradigm for understanding addiction. 

Why do people with addiction use drugs self-destructively? Why don’t they quit out of self-concern? Why does the rat in the experiment, alone in a cage, press the lever again and again for cocaine—to the point of death? In this pathbreaking book What Would You Do Alone in a Cage with Nothing But Cocaine?: A Philosophy of Addiction (Princeton UP, 2026), Johns Hopkins University professor Pickard proposes a new paradigm for understanding the puzzle of addiction. For too long, our thinking has been hostage to a false dichotomy: either addiction is a brain disease, or it is a moral failing. Pickard argues that it is neither, and that both models stifle addiction research and fail people who need help. 

Drawing on her expertise as an academic philosopher and her clinical work in a therapeutic community, Pickard explores the meaning of drugs for people with addiction and the diverse factors that keep them using despite the costs. People use drugs to cope with suffering—but also to self-harm, or even to die. Some identify as “addicts," while others are in denial or struggle with cravings and self-control. Social, cultural, and economic circumstances are crucial to explaining addiction—but brain pathology may also matter. By integrating addiction science with philosophy, clinical practice, and the psychology and voices of people with addiction themselves, Pickard shows why there is no one-size-fits-all theory or ethics of addiction. The result is a heterogeneous and humanistic paradigm for understanding and treating addiction, and a fresh way of thinking about responsibility, blame, and relationships with people who use drugs.

Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). Her new book, Addiction, Inc.: Medication-Assisted Treatment and America's Forgotten War on Drugs, will be released in April 2026.

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In 99 Ways to Die: And How To Avoid Them (St. Martins Press, 2026) emergency medicine doctor Ashley Alker presents an illuminating, hilarious, and practical guide to 99 of the most terrifying ways to die and how to avoid them. Dr. Alker is a self-described death escapologist—or, in more familiar terms, an emergency medicine doctor. She has seen it all, from flesh-eating bacteria to the work of a serial killer to the more mundane but no less deadly, and her work outwitting the end has uniquely prepared her to write this book. Dr. Alker manages to shock readers while making them laugh, educating them on how to outsmart a wide range of deadly situations and conditions. Many of the chapters include stories from her experiences in life and medicine, at times heartwarming, others heartbreaking. Sections include explorations of sex, poison, drugs, biological warfare, disease, animals, crime, the elements, and much more. An Anthony Bourdain-style greatest hits tour of death, 99 Ways to Die is entertaining while it informs. Full of valuable advice and wild stories, this riveting read might just save your life.

Rebekah Buchanan is a Professor of English and Director of English Education at Western Illinois University. Her research focuses on feminism, activism, and literacy practices in youth culture, specifically through zines and music.

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Why is cows' milk, which few nonwhite people can digest, promoted as a science-backed dietary necessity in countries where the majority of the population is lactose-intolerant? Why are gigantic new dairy farms permitted to deplete the sparse water resources of desert ecosystems? Why do thousands of U.S. dairy farmers every year give up after struggling to recoup production costs against plummeting wholesale prices?

Exploring these questions and many more, Spoiled: The Myth of Milk as Superfood (Columbia UP, 2023) is an unflinching and meticulous critique of the glorification of fluid milk and its alleged universal benefits. Anne Mendelson's groundbreaking book chronicles the story of milk from the Stone Age peoples who first domesticated cows, goats, and sheep to today's troubled dairy industry. Spoiled shows that drinking fresh milk was rare until Western scientific experts who were unaware of genetic differences in the ability to digest lactose deemed it superior to traditional fermented dairy products. Their flawed beliefs fueled the growth of a massive and environmentally devastating industry that turned milk into a cheap, ubiquitous commodity.

Mendelson's wide-ranging account also examines the consequences of homogenization and refrigeration technologies, the toll that modern farming takes on dairy cows, and changing perceptions of raw milk since the advent of pasteurization. Unraveling the myths and misconceptions that prop up the dairy industry, Spoiled calls for more sustainable, healthful futures in our relationship with milk and the animals that provide it.

Melek Firat Altay is a neuroscientist, biologist and musician. Her research focuses on deciphering the molecular and cellular mechanisms of neurodegenerative and neurodevelopmental disorders.

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Answers to the question 'what is medical progress?' have always been contested, and any one response is always bound up with contextual ideas of personhood, society, and health. However, the widely held enthusiasm for medical progress escapes more general critiques of progress as a conceptual category.

From the intersection of intellectual history, philosophy, and the medical humanities, in Making Medical Progress: History of a Contested Idea (Cambridge UP, 2025) Dr. Vanessa Rampton sheds light on the politics of medical progress and how they have downplayed the tensions between individual and social goods. She examines how a shared consensus about its value gives medical progress vast political and economic capital, revealing who benefits, who is left out, and who is harmed by this narrative. From ancient Greece to artificial intelligence, exploring the origins and ethics of different visions of progress offers valuable insight into how we can make them more meaningful in future. This title is also available as open access on Cambridge Core.

This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda’s interviews on New Books with Miranda Melcher, wherever you get your podcasts.

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What if the tools that shaped your life’s work were rooted in unimaginable evil?

In this haunting episode, Rabbi Marc Katz sits down with Dr. Howard Alan Israel to discuss Nazi Anatomy Lessons: A Dissection of Evil, a book born from a single, shattering moment in an operating room. For over twenty years, Dr. Israel had prepared for surgeries using the same anatomy atlas—methodically studying each illustration, planning for every variation, and building a career marked by innovation, research, and the training of future surgeons. Then a colleague changed everything with one sentence: the atlas had been created by Nazi doctors.

That revelation launched a thirty-year journey into the moral abyss—an investigation into who these anatomists were, who their “subjects” had been, and how healers became murderers. Dr. Israel began to confront terrifying questions: Was his career built, in part, on the suffering of victims? How could such knowledge remain hidden in plain sight for decades? And how does a profession devoted to healing become an instrument of genocide?

Together, Rabbi Katz and Dr. Israel explore not only the historical horror of Nazi medicine, but the urgent bioethical questions it raises today. As genocide remains a recurring human reality, this conversation asks what must change in our moral frameworks, institutions, and education to prevent the transformation of healers into agents of destruction—and how we might instead build a society committed to healing rather than harm.

Rabbi Marc Katz is the author of Yochanan's Gamble: Judaism's Pragmatic Approach to Life.

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In this eye-opening chronicle of scientific research on the brain in the early Cold War era, the acclaimed historian Andreas Killen traces the complex circumstances surrounding the genesis of our present-day fascination with this organ.

The 1950s were a transformative, even revolutionary decade in the history of brain science. Using new techniques for probing brain activity and function, researchers in neurosurgery, psychiatry, and psychology achieved dramatic breakthroughs in the treatment of illnesses like epilepsy and schizophrenia, as well as the understanding of such faculties as memory and perception. Memory was the site of particularly startling discoveries. As one researcher wrote to another in the middle of that decade, “Memory was the sleeping beauty of the brain—and now she is awake.” Collectively, these advances prefigured the emergence of the field of neuroscience at the end of the twentieth century.

But the 1950s also marked the beginning of the Cold War and a period of transformative social change across Western society. These developments resulted in unease and paranoia. Mysterious new afflictions—none more mystifying than “brainwashing”—also appeared at this time. Faced with the discovery that, as one leading psychiatrist put it, “the human personality is not as stable as we often assume,” many researchers in the sciences of brain and behavior joined the effort to understand these conditions. They devised ingenious and sometimes transgressive experimental methods for studying and proposing countermeasures to the problem of Communist mind control. Some of these procedures took on a strange life of their own, escaping the confines of the research lab to become part of 1960s counterculture. Much later, in the early 2000s, they resurfaced in the War on Terror.

These stories, often told separately, are brought together by the historian Andreas Killen in this chronicle of the brain’s mid-twentieth-century emergence as both a new research frontier and an organ whose integrity and capacities—especially that of memory—were imagined as uniquely imperiled in the 1950s. Nervous Systems: Brain Science in the Early Cold War (Harper, 2023) explores the anxious context in which the mid-century sciences of the brain took shape and reveals the deeply ambivalent history that lies behind our contemporary understanding of this organ.

Paul Lerner is Professor of History at the University of Southern California where he directs the Max Kade Institute for Austrian-German-Swiss Studies. He can be reached at [email protected] and @PFLerner.

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How healthy you are is dependent on where you live. Americans suffer more cancers, heart disease, mental illness, and other chronic diseases than those who live in other wealthy nations, despite having the most expensive healthcare system in the world. Why? Embark on a journey to unravel the profound impact of public policies on American health from before birth in Born Sick in the USA: Improving the Health of a Nation (Cambridge UP, 2026). Delve into the intricate web where economic inequality weaves a tapestry of sickness stemming from a highly stressed society. This compelling read illuminates the need for transformative change in social safety nets and public policies to uplift national health and well-being. Through vivid storytelling, the book unveils the symptoms, diagnosis, and 'medicine' required to steer the nation toward a healthier future. Join the movement for a healthier America by embracing the insightful revelations and empowering calls to action presented within the pages of this eye-opening book. Contact the author at: [email protected] 

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In the seventeenth and eighteenth centuries, venereal disease, or the 'pox,' was a dreaded diagnosis throughout Europe. Its ghastly marks, along with their inexorable link to sex, were so stigmatizing that it was commonly called 'the secret disease.' How do we capture everyday experiences of a disease that so few people admitted having? In The Dreaded Pox: Sex and Disease in Early Modern London (Cambridge UP, 2026), Dr. Olivia Weisser presents a remarkable history that invites readers into the teeming, vibrant pox-riddled streets of early modern London. She uncovers the lives of the poxed elite as well as of the maidservants and prostitutes who left few words behind, showing how marks of the disease offered a language for expressing acts that were otherwise unutterable. This new history of sex, stigma, and daily urban life takes readers down alleys where healers peddled their tinctures, enters kitchens and gardens where ordinary sufferers made cures, and listens in on intimate exchanges between patients and healers in homes and in taverns.

This interview was conducted by Dr. Miranda Melcher whose book focuses on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. You can find Miranda’s interviews on New Books with Miranda Melcher, wherever you get your podcasts.

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