What's Up Docs?

BBC Radio 4

In this BBC Radio 4 podcast, Drs Chris and Xand van Tulleken are on a mission to help us take better care of ourselves.Although they are identical twins, Chris and Xand are very different and they never stop thinking and arguing about science and health. They want to lead healthy, happy lives and as doctors, they want this for everyone. Yet they tussle over how best to get there.When it comes to looking after our own health, it can be confusing. Medicine and science produce amazing new treatments and diagnostics every day and we are bombarded with so many headlines and pieces of advice; but how are we supposed to know what's really best for us and then successfully apply it to our lives? Drs Chris and Xand van Tulleken embrace this challenge; even as they marvel at the scientific breakthroughs, they grapple with the competing claims about health, wellbeing and how to live. From understanding testosterone therapies to microplastics in our diets, and the concept of 'hangriness' to the power of saying no - this podcast deals with the health stresses we all face every day, while taking on board how the decisions by corporations and governments affect all our health. Each episode, Chris and Xand are joined by an expert guest to examine the latest research, psychological insights, and data, to help listeners navigate the overwhelming amount of information and advice out there. They talk about the trials and tribulations in their own lives in their characteristically witty way - each teasing the other as they search for solutions. Xand has trouble sleeping , Chris has noisy knees, one of them has got an embarrassing itch. They have different ways of looking at things and find it really helpful to get the other one's point of view. These doctors are trying their best and encouraging listeners to do the same.

  • 29 minutes 55 seconds
    Doctors' Notes: Hearing Loss

    Drs Chris and Xand continue their conversation about hearing loss with Prof Doris Bamiou, Professor of Neuroaudiology at the UCL Ear Institute, and Honorary Consultant in Audiological Medicine at the University College London Hospitals.

    Chris and Xand want to know how cognitive processing of sound works, what audio processing disorder is, why it happens, how it is diagnosed, and the external factors like neurodivergence and age that interact with it. They also examine the popular earplugs that filter speech, including whether they actually help with audio processing and how to use them responsibly, and hear Prof Bamiou’s personal and clinical perspective on hearing loss.

    If you’d like to share your thoughts on this or any other topic covered on the podcast, you email us at [email protected] or Whatsapp on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Prof Doris Bamiou Producer: Jo Rowntree Executive Producer: Rami Tzabar Editor: Kirsten Lass Assistant Producer: Maia Miller-Lewis Researcher: Mili Ostojic Tech Lead: Reuben Huxtable Social Media: Leon Gower Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4.

    16 December 2025, 7:03 am
  • 28 minutes 59 seconds
    What can you do about hearing loss?

    Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.

    In this episode, Chris and Xand dive into the physical side of hearing loss. What is the cocktail party problem, and why does it get worse with age? How does hearing work? What causes hearing loss? How can we protect our hearing? How can we manage hearing loss? What is tinnitus and how is it treated?

    They explore the physical structures behind our hearing, the causes that can lead to physical changes and hearing loss, why it gets more difficult with age to distinguish speech in busy places, and the top tips you can use to protect and manage your hearing.

    Joining them to discuss this is Prof Doris Bamiou, Professor of Neuroaudiology at the UCL Ear Institute, and Honorary Consultant in Audiological Medicine at the University College London Hospitals.

    If you want to get in touch, you can email us at [email protected] or WhatsApp us on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Prof Doris Bamiou Researcher: Mili Ostojic Producer: Faye Lyons White Social Media Producer: Leon Gower Executive Producer: Rami Tzabar Editor: Jo Rowntree Tech Lead: Reuben Huxtable Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4

    16 December 2025, 7:00 am
  • 21 minutes 31 seconds
    Doctors' Notes: Dopamine

    Chris and Xand continue their conversation about dopamine with Masud Husain, Professor of Neurology & Cognitive Neuroscience at the University of Oxford. They explore how he first became interested in dopamine, what happens when dopamine systems become overactive, underactive, or disrupted, and whether we have any real control over our dopamine at all. Masud also shares the one thing he wishes everyone understood about dopamine.

    If you’d like to share your thoughts on this or any other topic covered on the podcast, you email us at [email protected] or Whatsapp on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Professor Masud Husain Producer: Maia Miller-Lewis Executive Producer: Rami Tzabar Editor: Jo Rowntree Researcher: Grace Revill Tech Lead: Reuben Huxtable Social Media: Leon Gower Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4.

    9 December 2025, 7:03 am
  • 28 minutes 32 seconds
    Can you be ‘addicted to dopamine’?

    Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken untangle the confusion around every aspect of our health and wellbeing.

    In this episode, they’re diving into dopamine – one of the most talked-about chemicals in modern wellness culture. But what is dopamine, really? What role does it play in pleasure, motivation, learning, and movement? And how accurate are ideas like “dopamine hits”, “dopamine detoxes”, or being “addicted to dopamine”?

    Chris and Xand speak to Masud Husain, Professor of Neurology & Cognitive Neuroscience at the University of Oxford, to cut through the myths and find out what dopamine does, what it doesn’t do, and why understanding it properly might change the way we think about our behaviour and our brains.

    If you want to get in touch, you can email us at [email protected] or WhatsApp us on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Professor Masud Husain Producer: Maia Miller-Lewis Executive Producer: Rami Tzabar Editor: Jo Rowntree Researcher: Grace Revill Tech Lead: Reuben Huxtable Social Media: Leon Gower Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4

    9 December 2025, 7:00 am
  • 20 minutes
    Doctors' Notes: Beliefs

    Chris and Xand continue their conversation about belief with Ryan McKay, Professor of Psychology at Royal Holloway, University of London.

    They want to know why some beliefs take hold so strongly, what’s happening in our brains when we hold on to them, and how trust, identity, and community shape what we believe. Beyond that, they’ll explore why health beliefs can be so difficult to shift, and whether it’s ever really possible to change someone’s mind. From the psychology of delusions to the spread of everyday health narratives, this episode dives deeper into the mechanics of belief.

    If you’d like to share your thoughts on this or any other topic covered on the podcast, you email us at [email protected] or Whatsapp on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Professor Ryan McKay Producer: Maia Miller-Lewis Executive Producer: Rami Tzabar Editor: Jo Rowntree Researcher: Grace Revill Tech Lead: Reuben Huxtable Social Media: Leon Gower Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4

    2 December 2025, 7:03 am
  • 28 minutes 40 seconds
    Does what we believe about our health affect it?

    Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken confront the confusion around every aspect of our health and wellbeing.

    In this episode, they’re asking why beliefs about our bodies are so powerful? We often think of belief as something soft – just ideas in our heads. But beliefs can shape how we experience pain, how we heal, and even how societies behave. In health, they can influence whether treatments work and how symptoms are felt.

    So what actually are beliefs? Why do we them, and how do they form? And can changing what we believe about our bodies actually change how we feel?

    To help answer these questions, Chris and Xand are joined by Ryan McKay, Professor of Psychology at Royal Holloway, University of London, and an expert on the psychology of belief.

    If you want to get in touch, you can email us at [email protected] or WhatsApp us on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Professor Ryan McKay Producer: Maia Miller-Lewis Executive Producer: Rami Tzabar Editor: Jo Rowntree Researcher: Grace Revill Tech Lead: Reuben Huxtable Social Media: Leon Gower Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4

    2 December 2025, 7:00 am
  • 24 minutes 57 seconds
    Doctors' Notes: Dry Skin

    Drs Chris and Xand continue their conversation about dry skin with Dr Tess McPherson, Associate Professor of Paediatric and Adolescent Dermatology at the University of Oxford.

    The docs want to know what eczema is, why it happens, whether it is worth eliminating triggers and whether topical steroids are an effective treatment. They also explore the stigma around skin conditions and what we can all do to address it, and hear Dr McPherson’s personal and clinical perspective on dry skin and skincare in general.

    If you’d like to share your thoughts on this or any other topic covered on the podcast, you email us at [email protected] or Whatsapp on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Dr Tess McPherson Researcher: Mili Ostojic Producer: Faye Lyons White Assistant Producer: Maia Miller-Lewis Social Media Producer: Leon Gower Executive Producer: Rami Tzabar Editor:Jo Rowntree Tech Lead: Reuben Huxtable Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4.

    25 November 2025, 7:03 am
  • 29 minutes 10 seconds
    How should you relieve dry skin?

    Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.

    In this episode, Chris and Xand dive into dry skin and how it can be relieved. Why does dry skin happen? How can your washing and cleansing routine affect your skin? Should you use moisturisers, and how do they work? Can you use too many products? They explore the biology of dry skin, whether it can be prevented, the trends surrounding the care of dry skin, and the science of moisturisers.

    Joining them to discuss this is Dr Tess McPherson, Associate Professor of Paediatric and Adolescent Dermatology at the University of Oxford and consultant dermatologist at Oxford University Hospitals.

    If you want to get in touch, you can email us at [email protected] or WhatsApp us on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Dr Tess McPherson Researcher: Mili Ostojic Producer: Faye Lyons White Assistant Producer: Maia Miller-Lewis Social Media Producer: Leon Gower Executive Producer: Rami Tzabar Editor:Jo Rowntree Tech Lead: Reuben Huxtable Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4

    25 November 2025, 7:00 am
  • 27 minutes 4 seconds
    Doctors' Notes: Hot and Cold Therapies

    Chris and Xand continue their conversation about body temperature with Dr Heather Massey, Associate Professor of extreme environments and physiology at the University of Portsmouth.

    Drs Chris and Xand van Tulleken want to know how cold water swimming and contrast therapy can challenge your body temperature and what the benefits might be. They also explore whether everyone should be challenging their body temperature, and whether there are alternatives to the extreme methods. They also hear Dr Massey’s personal and clinical perspective on cold water swimming.

    If you’d like to share your thoughts on this or any other topic covered on the podcast, you email us at [email protected] or Whatsapp on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Dr Heather Massey Producer: Faye Lyons-White and Maia Miller-Lewis Executive Producer: Rami Tzabar Editor: Jo Rowntree Researcher: Mili Ostojic Tech Lead: Reuben Huxtable Social Media: Leon Gower Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4.

    18 November 2025, 7:03 am
  • 28 minutes 55 seconds
    Do hot and cold therapies work?

    Welcome to What’s Up Docs?, the podcast where doctors and identical twins Chris and Xand van Tulleken cut through the confusion around every aspect of our health and wellbeing.

    In this episode, Chris and Xand dive into body temperature and how it can be challenged. How does the human body regulate its core and skin temperature? Can you change your body temperature from its average value? Should you challenge your body temperature by exposing yourself to hot environments? They explore the biology of body temperature, the impact of cold therapies and look at the claimed benefits of saunas.

    Joining them to discuss this is Dr Heather Massey, Associate Professor of extreme environments and physiology at the University of Portsmouth.

    If you want to get in touch, you can email us at [email protected] or WhatsApp us on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Dr Heather Massey Researcher: Mili Ostojic Producers: Faye Lyons White and Maia Miller-Lewis Social Media Producer: Leon Gower Executive Producer: Rami Tzabar Editor: Jo Rowntree Tech Lead: Reuben Huxtable Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Melvin Rickarby

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4

    18 November 2025, 7:00 am
  • 19 minutes 7 seconds
    Doctors' Notes: All-or-Nothing Thinking

    Drs Chris and Xand continue their conversation about all-or-nothing thinking with Kimberley Wilson, Chartered Psychologist, author and host of the new mental health podcast, Complex.

    Chris and Xand want to know how all-or-nothing thinking interacts with out socio-politics, and how age and our relationship with social media shapes our tendency towards binary thought patterns.

    If you’d like to share your thoughts on this or any other topic covered on the podcast, you email us at [email protected] or Whatsapp on 08000 665 123.

    Presenters: Drs Chris and Xand van Tulleken Guest: Kimberley Wilson Producer: Maia Miller-Lewis Executive Producer: Rami Tzabar Editor: Jo Rowntree Researcher: Kimberley Wilson Tech Lead: Reuben Huxtable Social Media: Leon Gower Digital Lead: Richard Berry Composer: Phoebe McFarlane Sound Design: Ruth Rainey

    At the BBC: Assistant Commissioner: Greg Smith Commissioning Editor: Rhian Roberts

    A Loftus Media production for BBC Radio 4.

    11 November 2025, 7:03 am
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