For her most of her adult life, Oprah has struggled with her weight. She never dreamed in her lifetime, there would be medications that could help her as well as millions of others. On this episode of The Oprah Podcast, Oprah is joined by Dr. Ania Jastreboff, leading endocrinologist and associate professor at Yale School of Medicine in front of a live audience in New York City.

They discuss Dr. Ania’s new book, Enough: Your Health, Your Weight, and What It's Like To Be Free which delivers a deeply transformational message: there is a path to healing from the blame and shame of obesity to lead the life you have always wanted. Dr. Jastreboff shares the science behind why obesity is a disease and not a question of willpower and why the new medications have been so effective for tens of millions of people. Oprah shares her decades-long public struggle with her weight and reveals how her experience with a GLP-1 medication has given her a freedom and energy she never thought possible. Plus, 23-time grand slam tennis champion Serena Williams joins the conversation and opens up about her own battle with weight calling it “the one opponent she couldn't defeat.” Serena also reveals why - after her initial skepticism - she decided to start a GLP-1 medication. Finally, we hear from guests in the audience about how the GLP-1 medications have changed their lives. One of those guests is Stedman Graham’s nephew Julius who shares with heartbreaking honesty how his weight held him back for decades. He says that after losing 64 pounds on a GLP-1 medication he is now “fully alive.”

BUY THE BOOK!

https://www.simonandschuster.com/books/Enough/Ania-M-Jastreboff/9781668217283

00:00:00 - Welcome Dr. Ania Jastreboff, author of “Enough”

00:01:30 - 74% of americans are overweight

00:04:30 - Obesity is a disease

00:07:30 - We live in an obesogenic environment

00:09:10 - Genetic link to obesity

00:10:50 - You can’t willpower away obesity

00:13:30 - Defining food noise

00:18:30 - Recalibrating your “enough point”

00:22:30 - Some people have food noise, others don’t

00:23:40 - Welcome Serena Williams

00:27:00 - Why Serena tried GLP-1s

00:29:30 - Everyone responds to GLP-1s differently

00:31:00 - How Serena feels on GLP-1s

00:40:00 - Why your body settles on an unhealthy “enough point”

00:42:00 - Welcome Julius, Stedman’s nephew

00:50:00 - How GLP-1s changed Julius

00:54:00 - Do you stay on GLP-1s forever?

01:02:00 - Can GLP-1s prevent obesity?

01:04:00 - Oprah wants GLP-1s available to all

01:05:40 - Dr. Ania wants people to understand obesity

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Oprah sits down with renowned organizational psychologist and professor Adam Grant to talk about lessons from his latest #1 New York Times bestselling book "Hidden Potential: The Science of Achieving Greater Things.” Known for his research on human potential, Grant shares how anyone can achieve greatness and unlock potential by cultivating character traits like resilience, curiosity, perseverance and embracing discomfort. He shares personal stories of overcoming his own limitations and insights from people who’ve accomplished the extraordinary. Joining the conversation is the first Black Chess Grandmaster Maurice Ashley and people from around the country via Zoom who desire to harness the power of hidden potential.

BUY THE BOOK!

'Hidden Potential: The Science of Achieving Greater Things' by Adam Grant:https://www.penguinrandomhouse.com/books/719611/hidden-potential-by-adam-grant/

Adam Grant 2026 Day-to-Day Calendar: Something to Think About: Daily Insight from the Psychologist and Author

https://www.amazon.com/Adam-Grant-2026-Day-Calendar/dp/152489933X

Adam Grant:

https://adamgrant.net/about/biography/

00:00:00 - Welcome Adam Grant, author of Hidden Potential

00:04:13 - How character and personality differ

00:06:10 - Action and confidence 

00:09:00 - Critics as coaches

00:11:50 - Standing in your values

00:14:15 - What makes a good leader

00:17:18 - First Black Chess Grandmaster Maurice Ashley 

00:22:45 - How potential gets overlooked 

00:24:10 - How ‘Hidden Potential’ helps educators

00:27:30 - Three priorities for a school to thrive 

00:30:25 - Tap into your hidden potential 

00:33:28 - Confidence in your ability to learn

00:34:50 - Managing perfectionism 

00:38:00 - Appreciate your progress 

00:39:30 - What keeps Oprah motivated

'Move by Move: Life Lessons on and Off the Chessboard' by Maurice Ashley:https://mauriceashley.com/move-by-move/

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Oprah sits down with world-renowned spiritual teacher, bestselling author and “fixer" Iyanla Vanzant for a powerful, soul-shifting conversation about her newest book "Spiritual Hygiene: A Practical Path for Clean Living, for Inner Authority, and for Divine Freedom." In this intimate and deeply personal episode Iyanla explains the transformative concept of spiritual hygiene—the idea that just as we tend to our physical hygiene our mental, emotional and spiritual well-being also require conscious, daily care. Iyanla shares what she’s learned and how she’s healed from her own childhood trauma as well as losing two of her adult daughters, Gemmia in 2003 and Nisa in 2023. Oprah and Iyanla are joined by audience members who bravely ask how they can cleanse their spirits of the pain, heaviness and generational burdens they’ve carried throughout their lives. Together they explore how spiritual hygiene offers clarity, courage and a way forward. This episode is a moving invitation to let go and step into a more grounded, spiritually spacious life.

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https://www.simonandschuster.com/books/Spiritual-Hygiene/Iyanla-Vanzant/9781668214121

00:00:00 - Welcome Iyanla Vanzant, author of ‘Spiritual Hygiene’ 

00:03:40 - Meaning of spiritual hygiene 

00:04:15 - Iyanla’s backstory

00:11:08 - The power of grief 

00:13:30 - Parenting with spiritual hygiene 

00:14:00 - Iyanla says she was a horrible mother 

00:15:25 - The distinction between wrong and bad 

00:17:50 - The meaning of divine freedom

00:19:00 - Everything is energy 

00:20:30 - Healing the pain of being a daddy-less daughter

00:30:20 - Create your own spiritual hygiene 

00:33:15 - How to be expressive with family 

00:37:40 - Reorder your story

00:38:10 - The life you signed up for 

00:40:00 - Look at far you’ve come 

00:41:40 - The guilt of choosing yourself 

00:46:15 - Always choose yourself 

00:48:02 - A sacred no and a spiritual yes 

00:52:00 - Everything has a purpose

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Oprah sits down with actor Jeremy Allen White and writer-director Scott Cooper for a fascinating conversation about their stirring new film, Springsteen: Deliver Me from Nowhere. The film is a revelatory look at Bruce Springsteen during a personal and professional crossroads; the film explores the mental health struggles and creative reckoning behind the making of his deeply personal album Nebraska. Oprah calls White’s Golden Globe–nominated performance “mesmerizing” and praises Cooper for “elevating quiet struggle into cinematic poetry,” describing the film as “a gift” and a meditation on “what it means to be human.” The film also stars Jeremy Strong, Odessa Young, Stephen Graham, Johnny Cannizzaro, Gaby Hoffman, Paul Walter Hauser and Grace Gummer.

SEE THE FILM!

Springsteen: Deliver Me from Nowhere, starring Golden Globe nominee Jeremy Allen White, written and directed by Scott Cooper, and distributed by 20th Century Studios is now available on Demand.

https://tv.apple.com/us/movie/springsteen-deliver-me-from-nowhere/umc.cmc.44ij3fzlajh43wxngtyxd6ioi

00:00:00 - Oprah introduces the movie Springsteen: Deliver Me From Nowhere 

00:03:22 - Oprah, Jeremy Allen White and Scott Cooper at Santa Barbara Film Festival

00:05:00 - Jeremy on getting cast as Bruce Springsteen 

00:06:30 - Scott on telling Springsteen’s story

00:08:35 - Scott on asking Bruce to make this film 

00:12:00 - How Jeremy prepared to become Bruce Springsteen

00:14:50 - Jeremy on learning guitar 

00:18:20 - Scott on using black and white photography for flashbacks 

00:25:27 - How playing Springsteen changed Jeremy 

00:28:10 - Scott on how making the movie changed him 

00:29:10 - Springsteen and mental illness

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Academy Award-nominated actors Hugh Jackman and Kate Hudson join The Oprah Podcast to discuss their upcoming extraordinary film Song Sung Blue which will be released in theaters on December 25. Song Sung Blue is a deeply moving love story about dreams and second chances. Based on a true story, Hugh and Kate portray the Milwaukee couple Mike and Claire Sardina, who were the legendary Neil Diamond tribute band duo known as "Lightning & Thunder.” The film is also an homage to Neil Diamond’s beloved catalogue of iconic songs. The podcast was recorded with a live audience who screened the film in New York City. The episode also features a surprise guest from Kate Hudson’s past, a Zoom surprise with viewers in Milwaukee and questions from the audience.

Song Sung Blue

In theaters everywhere Christmas Day.

https://www.focusfeatures.com/song-sung-blue

00:00:00 - Welcome Hugh Jackman and Kate Hudson, stars of Song Sung Blue

00:00:00 - Song Sung Blue movie preview

00:04:50 - Hugh Jackman on the Lightning and Thunder documentary

00:08:00 - Hugh and Kate react to reviews

00:10:15 - Oprah shares her love for Neil Diamond

00:11:48 - Movie clip

00:13:06 - How Hugh prepared to be a Neil Diamond impersonator

00:14:00 - Neil Diamond’s reaction to the movie

00:16:35 - Kate on her singing role

00:19:50 - On doing a Wisconsin accent

00:22:22 - Oprah surprises Kate Hudson

00:25:00 - Hugh Jackman on working with Kate Hudson

00:26:30 - Movie clip

00:29:50 - How the movie inspires

00:33:50 - The characters struggle with substance abuse

00:34:45 - How Hugh and Kate developed on-screen chemistry

00:39:20 - Hugh on his performance

00:39:55 - Movie clip

00:44:03 - Oprah surprises Lightning and Thunder fans

00:51:58 - Hugh shares Neil Diamond story

Song Sung Blue (2008)

A Documentary by Greg Kohs

http://watch.songsungblue.com

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Oprah sits down with world renowned, history-making ballet dancer Misty Copeland for an intimate and deeply reflective conversation as Misty takes her final bow with the American Ballet Theatre. As the prestigious company’s first Black female principal dancer, Misty looks back on her incomparable career that changed the face of classical ballet by expanding who gets to be seen, centered and celebrated on the world’s most iconic stages. We also hear from one of Misty’s longtime mentors whose guidance helped shape her career along with listeners of all ages from across the country seeking Misty’s wisdom, encouragement and perspective as they pursue their own unique paths. Misty shares lessons on resilience, courage and gratitude we can all learn from as well as the legacy she hopes to continue building for young dancers of color. Misty shares her rigorous process of preparing for her final dance at her retirement gala of which Oprah serves as co-chair. Presented by Walmart, this episode celebrates Misty’s inspiring path and the joy of sharing your unique gifts with the world. Misty also discusses her two newest books: Letters to Misty: How to Move Through Life with Confidence and Grace and Bunheads, Act 2: The Dance and Courage, which you can find on Walmart.com.

BUY THE BOOKS:

Letters to Misty: How to Move Through Life with Confidence and Grace https://www.walmart.com/ip/Letters-to-Misty-How-to-Move-Through-Life-with-Confidence-and-Grace-Hardcover-9781534443037/12993719964?classType=REGULAR&from=/search

Bunheads, Act 2: The Dance and Courage https://www.walmart.com/ip/Bunheads-ACT-2-The-Dance-of-Courage-Hardcover-9780399547683/15039751551

00:00:00 - Welcome Misty Copeland, Author of Letters to Misty

00:02:45 - Performing One Last Time: Her Emotions

00:06:28 - Knowing When It’s Time to Step Away

00:08:20 - Physical + Emotional Pain Behind Dancing

00:10:50 - Imagining Her Final Bow

00:13:21 - Misty’s Childhood

00:15:15 - How the Boys and Girls Club Impacted Her

00:18:15 - Invitation to American Ballet Theatre

00:19:00 - Being the Only Black Woman at ABT

00:23:05 - Welcome former ABT director John Meehan

00:25:15 - Challenges of Starting Ballet Later in Life

00:26:50 - Debbie Allen’s Impact on Her Career

00:28:55 - Advice for Young Dancers of Color

00:31:28 - What She Wants People to Know About Ballet

00:32:35 - Life + Goals Beyond Ballet

00:36:16 - The Loneliness of Being a Trailblazer

00:42:25 - Painting Ballet Shoes to Match Her Skin Tone

00:45:42 - Misty and her siblings now

00:47:42 - Misty on her husband

00:48:50 - Becoming ABT Principal Dancer

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Oprah and a live audience of mostly men are in a lively conversation with author, entrepreneur, NYU professor and podcaster Scott Galloway about his new book, Notes on Being a Man. Galloway’s #1 New York Times bestseller has ignited a nationwide discussion around what many see as a crisis facing young men today. In this candid discussion, men open up about manhood, vulnerability, and the unique challenges facing young men in modern America. Scott answers questions from the audience and opens up about his own personal journey of being a man and a father to two sons. BUY THE BOOK! 'Notes on Being a Man' by Scott Galloway: https://www.simonandschuster.com/books/Notes-on-Being-a-Man/Scott-Galloway/9781668084359 Chapters: 00:00:00 — Intro: Scott Galloway, Notes on Being a Man 00:01:20 — Why anger is the only “allowed” male emotion 00:02:40 — Men want role models 00:05:10 — Male friendships in decline 00:07:25 — Screen time and declining well-being in young men 00:09:40 — Why many young men don’t ask women out 00:11:38 — Relationships are life’s greatest reward 00:12:36 — Scott’s upbringing 00:13:50 — Rule #1 of being a good man 00:17:45 — Building a personal code of conduct 00:20:50 — Moms are sounding the alarm too 00:22:38 — Learning to be vulnerable 00:26:27 — Balancing self-love with finding love 00:27:52 — The 3 things women want in men 00:30:48 — Why taking risks is difficult 00:32:42 — Staying on the right path 00:36:30 — Scott on toxic masculinity 00:39:26 — How men can show up for each other 00:43:10 — What Scott would tell his younger self 00:46:42 — Is dating getting harder? 00:50:38 — How parents can support young men Follow Oprah Winfrey on Social: https://www.instagram.com/oprahpodcast/ https://www.facebook.com/oprahwinfrey/ Listen to the full podcast: https://open.spotify.com/show/0tEVrfNp92a7lbjDe6GMLI https://podcasts.apple.com/us/podcast/the-oprah-podcast/id1782960381

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In a groundbreaking conversation about one of the fastest-growing cultural shifts of our time: Oprah talks with leading experts and a live audience about the decision to go “no contact” with a family member. It’s estimated one third of Americans have cut off ties or is estranged from their family. Once considered taboo, family estrangement is now being openly discussed by people of all ages who are redefining what healthy boundaries look like in family relationships. In this revealing episode, Oprah and best-selling psychologists unpack this rising trend of people distancing themselves from parents, siblings, or relatives they consider toxic. Adult children and parents who have chosen to go "no contact” share their stories and their reasons behind this difficult decision. Oprah and the audience explore the emotional, cultural and psychological issues behind the movement - ranging from trauma and generational patterns to mental-health awareness and the expanded definition of abuse.

BUY THE BOOK!

DR. JOSHUA COLEMAN - RULES OF ESTRANGEMENT

https://www.penguinrandomhouse.com/books/622584/rules-of-estrangement-by-joshua-coleman-phd/

DR. LINDSAY GIBSON - ADULT CHILDREN OF EMOTIONALLY IMMATURE PARENTS How to Raise an Emotionally Mature Child by Lindsay C. Gibson, PsyD:

https://www.newharbinger.com/9781626251700/adult-children-of-emotionally-immature-parents/

NEDRA GLOVER TAWWAB - DRAMA FREE & THE BALANCING ACT

https://www.penguinrandomhouse.com/books/706826/drama-free-by-nedra-glover-tawwab/

https://www.penguinrandomhouse.com/books/760457/the-balancing-act-by-nedra-glover-tawwab/

Chapters:

00:01:00 - One-third of Americans are going no contact—what it means

00:02:00 - Younger generations choosing no contact for mental health

00:02:50 - Guest: Dr. Joshua Coleman, Rules of Estrangement

00:03:40 - How the concept of family has shifted

00:06:27 - Guest: Dr. Lindsay Gibson, Adult Children of Emotionally Immature Parents

00:09:30 - How to tell if a parent is emotionally immature

00:10:25 - Guest: Nedra Tawwab, Drama Free

00:12:20 - Dr. Coleman on his daughter cutting contact

00:14:22 - Chris shares going no contact

00:18:48 - Why Chris made the decision

00:19:30 - Talking to kids about going no contact

00:23:04 - What kids learn from cutting off difficult relatives

00:24:39 - Bristyl shares her no-contact story

00:26:20 - Will the longing for a mother–daughter bond fade?

00:29:00 - Expanded definitions of harm, neglect, trauma, abuse

00:30:00 - Bree shares her no-contact choice

00:33:37 - Is forgiveness possible?

00:37:26 - Christy shares her daughter’s estrangement

00:39:40 - Do some estranged kids lack conflict resolution skills?

00:43:20 - Kendall on going no contact with her adult son

00:44:50 - Why parents are criticized for going no contact

00:47:20 - Aaron shares his daughter cut ties with him

00:53:25 - Have we gone too far?

00:54:48 - The one thing that can save your family relationship

00:58:10 - There are separate realities in every family

01:00:17 - Hadley shares her experience as a hospice nurse

01:05:00 - Why Hadley went no contact

01:09:00 - Parent child dynamic has shifted from role to relationship

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In a compelling conversation, Oprah talks with renowned psychic medium Laura Lynne Jackson about her new book Guided: The Secret Path to an Illuminated Life. Laura Lynne Jackson says she has the ability to communicate with people who have passed on to the afterlife. She believes we all have the same ability if we “stay open” to receiving messages or signs from the other side. It’s what Laura calls living an “illuminated life.” Laura says her psychic medium gift showed up for her at a very young age and she has been giving readings over the course of her life. She describes how everyone of us living on Earth “in the physical world” has a “Team of Light” or loved ones, spirit guides and even pets who have died and who are watching out for us and sending signs. Oprah and Laura Lynne Jackson are joined by several listeners who have questions and doubts about communicating with deceased loved ones. Brittany from Arizona shares how she asked for a specific sign and received it from her 7-year-old son, Bodhi, who tragically died in 2024. Do you believe in signs and messages from the afterlife? Laura Lynne Jackson is also the author of two New York Times Bestsellers, Signs: The Secret Language of The Universe and The Light Between Us: Stories from Heaven. Lessons for the Living.

BUY THE BOOK!

"Guided: The Secret Path to an Illuminated Life" by Laura Lynne Jackson

https://www.penguinrandomhouse.com/books/735734/guided-by-laura-lynne-jackson/

Chapters

00:00:00 - Welcome Laura Lynne Jackson, author of “Guided”

00:03:07 – Discovering her psychic abilities

00:04:40 – Realizing she’s also a medium

00:06:50 – The spiritual lives of children

00:09:30 – How her brain activity differs from others

00:11:00 – Understanding our “team of light”

00:12:50 – Hearing guidance from our spirit guides

00:15:00 – Asking for signs from the other side

00:16:30 – A mother’s story of signs from her late son

00:30:40 – What happens when we pass

00:37:00 – Talking to kids about signs

00:39:58 – Learning to trust the signs

00:45:00 – Honoring loved ones who’ve passed

00:48:15 - Signs from pets

00:50:40 – What Laura Lynne wants us to know about the other side

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In this episode of Oprah’s Book Club: Presented by Starbucks, Oprah and Ann Packer discuss Some Bright Nowhere, Ann’s poignant new novel and Oprah’s 120th Book Club selection. This book explores what happens when a wife's dying request shatters everything her husband believed about their 35 years together. Ann’s evocative and beautifully written novel inspired a thought-provoking conversation among readers at a Starbucks coffeehouse in New York City. As our audience discussed the inherent challenges and life-changing insights that come with the privilege and responsibility of caregiving, they were warmed by a Starbucks holiday classic: the Peppermint Mocha.

BUY THE BOOK!

https://www.harpercollins.com/products/some-bright-nowhere-ann-packer

00:00:00 - Welcome Ann Packer, author of ‘Some Bright Nowhere’

00:02:40 - Thando shares her feelings about the main characters 

00:04:50 - How Ann created the story 

00:06:50 - Ann knew the ending before she started

00:07:38 - Recurring theme in Ann’s books 

00:10:35 - Ann takes on hard questions 

00:14:50 - How Ann wrote from the male perspective 

00:17:07 - Support for male caregivers 

00:25:30 - Male and female caregiving differences 

00:30:38 - The difficulty of speaking your truth 

00:31:54 - The power of a dying wish 

00:33:48 - What cancer takes away from people 

00:39:29 - What can be learned from loss 

00:40:32 - Ann wants to normalize talking about death 

00:42:50 - How it feels to hit send on your finished book

SUPPORT THE SHOW

Learn more about Jack’s Caregiver Coalition - a national non-profit that ensures no man should care alone. Jack’s is a center for empowerment, support, and community for men who are caregivers. 

https://www.jackscaregiverco.org/

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Oprah talks with world-renowned restaurateur Will Guidara about his New York Times bestselling book, Unreasonable Hospitality that has sold over 1 million copies. Will’s abiding belief is that focusing on providing excellent service to others can transform not only your business, but your entire life. Recorded with a live audience in New York City, this episode also features Will’s longtime friend and mentor, Chef Daniel Boulud of New York’s legendary restaurant Daniel. Presented by Walmart, this podcast is an invitation to use your unique gifts and talent to elevate the lives of those around you. You can find Will’s book, Unreasonable Hospitality, at Walmart.com. Will’s upcoming book Unreasonable Hospitality: The Field Guide is also available for preorder.

BUY THE BOOK!

Unreasonable Hospitality: The Remarkable Power of Giving People More Than They Expect, published by Optimism Press and written by Will Guidara, is available wherever books are sold. Unreasonable Hospitality: The Field Guide is available for preorder.

Unreasonable Hospitality: https://www.walmart.com/ip/Unreasonable-Hospitality-The-Remarkable-Power-of-Giving-People-More-Than-They-Expect-Hardcover-9780593418574/319309554

00:00:00 - Welcome Will Guidara, author of ‘Unreasonable Hospitality’

00:03:35 - Handling last place at the World’s 50 Best Restaurants

00:07:45 - Setting the goal to become No. 1

00:08:45 - Will’s first fine dining experience

00:13:46 - The impact we have on others

00:16:30 - Living with intention

00:18:09 - The nobility of service

00:20:50 - Meeting Chef Daniel Boulud

00:23:00 - Taking his father to Daniel’s after his mother’s passing

00:25:19 - Chef Daniel Boulud

00:27:45 - What Chef Boulud learned from Will

00:31:30 - Examples of unreasonable hospitality

00:35:20 - Caring for difficult people

00:36:45 - The charitable assumption

00:41:20 - Mindsets and practices

00:43:40 - Oprah and Will have this in common

00:45:00 - The best gift Will ever received

SHOP THE SET

Better Homes & Garden Ezra Accent Chair: https://www.walmart.com/ip/Better-Homes-Gardens-Ezra-Accent-Chair-Olive-Green/6832971398?classType=VARIANT&athbdg=L1300&from=/search&wmlspartner=wlpa&cn=FY25-ENTP-PMAX_cnv_dps_dsn_dis_ad_entp_e_n&adid=22222222297_0000000000_21407473164&veh=sem&vtcWeb=eviaA8Ad89fe38QBUyb9gE&expiryTime=1756505947449&c=mWebSmartBanner

Better Homes & Garden Miller Drum End Table: https://www.walmart.com/ip/Better-Homes-Gardens-Essentials-End-Table-Walnut/13665865382

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