• 1 hour 1 second
    #92 -Professor Kumar Ramakrishna Explains The Rise Of Self-Radicalization

    Thank you for checking out my episode with Prof Kumar Ramakrishna. This episode is brought to you in partnership with the S Rajaratnam School of International Studies. For more information on the school and its programmes see here - https://rsis.edu.sg/publications/rsis-publications/annual-reviews/Professor Kumar Ramakrishna is one of Southeast Asia's foremost authorities on terrorism, extremism, and national security. He is Dean of the S. Rajaratnam School of International Studies (RSIS) at Nanyang Technological University, where he also holds the President's Chair in National Security Studies and serves as Research Adviser to the International Centre for Political Violence and Terrorism Research. He was first appointed Dean in January 2023 and re-appointed for a further term from January 2026, he has spent more than 25 years at RSIS and its predecessor, the Institute of Defence and Strategic Studies, which he joined in 2000.TIMESTAMPS:0:00 Trailer 0:42 Introduction 1:21 What the Pre-9/11 Security Mindset Missed 4:51 The Paradigm Shift After Ground Zero 10:01 Communists vs Jihadists: Two Kinds of True Believers 13:53 The Rational Logic of Suicide Bombing 18:07 Why Educated People Join Terrorist Groups 22:52 The Threats We Have Stopped Watching 31:13 Gaza and Singapore's Social Fabric 34:30 Understanding Hamas — and Iran 36:37 Singapore's Latent Fault Lines 39:46 Muscular Secularism 45:29 Securitising Of Identities 49:11 Inoculating Citizens Against Radicalisation 53:13 Family and Community as the First Defence 56:00 The Central Lesson: Sincerely Wrong 59:23 Advice for Fresh Graduates 59:47 ClosingThis is the 92nd episode Of The Front Row PodcastA huge thank you to our amazing Front Row Friends for supporting and advancing the podcast: @marinama2728@deborahchoi1455@annkowong@yewchoutan5876Full transcripts of episodes can be found here: https://www.ykeith.com/tag/podcast/Feel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected] access to every episode by subscribing for free on Spotify: https://creators.spotify.com/pod/show/keith-yap8 or Apple Podcasts: https://podcasts.apple.com/sg/podcast/front-row/id1771599400

    5 August 2026, 1:35 pm
  • 1 hour 14 minutes
    #91- Chandran Nair - Southeast Asia's Wake-Up Call Has Arrived -

    Chandran Nair is the founder and CEO of the Global Institute For Tomorrow (GIFT), an independent pan-Asian think tank based in Hong Kong committed to understanding the dynamic relationship between business, society, and the state, and to reshaping the rules of global capitalism.


    A Malaysian with a background in chemical engineering and biochemistry, he spent the first decades of his career in sustainability, rising to become chairman of Environmental Resources Management (ERM) for Asia Pacific, one of the region's leading environmental consultancies.

    He is a member of the executive committee of the Club of Rome and a regular speaker at global forums including the World Economic Forum and APEC.Nair is the author of three books: Consumptionomics, The Sustainable State: The Future of Government, Economy and Society, and most recently Dismantling Global White Privilege: Equity for a Post-Western World, which the Financial Times selected among its best books of the season.


    Drawing on more than thirty years of lived experience in China, Africa, Europe, and Southeast Asia, he has become one of Asia's most vocal thinkers on the idea of a post-Western world — arguing that the deepest legacy of colonialism is the capture of the mind, and that Asia's future depends on building strong institutions and defining a value proposition for itself rather than for others.This is the 91st episode Of The Front Row Podcast

    TIMESTAMPS

    0:00 Introduction 0:58 What The West Gets Wrong About China 6:07 China As A Civilisational State 13:18 Lee Kuan Yew's Warning Against Westernisation 16:08 The Capture Of The Elite Minds?21:24 Decolonising The Mind 34:25 How China Shapes The International Order 41:18 Why The West Fears China's Rise 45:50 Development, Not Sanctions: China In Africa51:31 Southeast Asia's Wake-Up Call 58:33 When The State Should Intervene 1:03:01 A Value Proposition For Ourselves 1:11:11 Advice For Young Graduates

    A huge thank you to our amazing Front Row Friends for supporting and advancing the podcast: @marinama2728@deborahchoi1455@annkowong@yewchoutan5876Full transcripts of episodes can be found here: https://www.ykeith.com/tag/podcast/Feel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected] access to every episode by subscribing for free on Spotify: https://creators.spotify.com/pod/show/keith-yap8 or Apple Podcasts: https://podcasts.apple.com/sg/podcast/front-row/id1771599400

    31 July 2026, 10:36 am
  • 1 hour 12 minutes
    #90 - How Deng Xiaoping's Visit To Singapore Changed China Forever - Professor Tan Kong Yam (In Partnership with RSIS)

    Thank you for checking out The Front Row Podcast and my interview with Professor Tan Kong Yam. This episode is brought to you in partnership with the S Rajaratnam School of International Studies. For more information on the school and its programmes see here - https://rsis.edu.sg/publications/rsis-publications/ For show notes and information on our collaboration, please go to ykeith.com/rsis GUEST DESCRIPTION:Professor Tan Kong Yam is Emeritus Professor of Economics at Nanyang Technological University and NTUC Endowed Professor at the S. Rajaratnam School of International Studies.He occupies an unusual position in the history of Singapore–China relations: he was in the room when Dr Goh Keng Swee first visited China. From 1985, when Deng Xiaoping invited Dr Goh Keng Swee to advise China on its economic development strategy, Tan served as Goh's chief assistant. Fluent in Mandarin, he sat close enough to Deng to take his own notes through the Sichuan accent, and travelled with the Singapore delegation through Beijing, Shanghai, and the coastal cities as the architecture of China's Special Economic Zones was being drawn. He went on to serve as chief economist of the Singapore government from 1999 to 2002, as a senior economist at the World Bank's Beijing office from 2002 to 2005, and as a member of the World Bank expert group advising the State Council on China's Eleventh Five-Year Plan. TIMESTAMPS0:00 Trailer1:18 Dr Goh's First Visit to China 5:30 The Chinese Psyche In PRC's Early Days 10:06 Dr Goh's Verdict On China's Potential 15:30 What China Was Like Post Revolution 17:30 Deng Visits Singapore 21:08 China As Yao Ming? 27:43 Fuzhou, A Young Mayor, And A Debt Repaid30:50 Why Xi's Generation Are Obsessed With Production 33:30 Prof Tan's Prediction 36:03 1989: When The Window Nearly Closed39:00 Lee Kuan Yew's Epiphany 42:50 Lee Kuan Yew Predicts China's Rise in 199549:44 What Singapore Understood That The West Did Not56:15 The Downside Of China's Ascendance 1:01:39 China's Capital Turns Towards ASEANThis is the 90th episode Of The Front Row PodcastA huge thank you to our amazing Front Row Friends for supporting and advancing the podcast: @marinama2728@deborahchoi1455@annkowong@yewchoutan5876Full transcripts of episodes can be found here: https://www.ykeith.com/tag/podcast/Feel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected] access to every episode by subscribing for free on Spotify: https://creators.spotify.com/pod/show/keith-yap8 or Apple Podcasts: https://podcasts.apple.com/sg/podcast/front-row/id1771599400

    20 July 2026, 10:00 am
  • 1 hour 11 minutes
    #89- Founder of Trip.Com on The Most Existential Challenge Of Our Time - James Liang

    Thank you for checking out The Front Row Podcast and my interview with James Liang. James Liang is the co-founder and executive chairman of Trip.com Group, the online travel company he helped launch in 1999 as Ctrip and built into one of the world's largest travel platforms, listed on Nasdaq and operating in more than forty countries. A gifted student who entered Fudan University at fifteen before taking a master's in computer science at the Georgia Institute of Technology, he served as Trip.com's chief executive from 2000 to 2006, and then made an unusual move: he stepped back at the height of the company's success to pursue a PhD in economics at Stanford.That second career reshaped him into one of Asia's most prominent voices on demography and innovation. Now a research professor of economics at Peking University's Guanghua School of Management and a co-founder of the Yuwa Population Research Institute, Liang has published in journals including Nature and The Quarterly Journal of Economics, and has written widely on population, education, and entrepreneurship. His books include The Demographics of Innovation and, most recently, Innovationism: A New Philosophy for the Age of AI.This conversation matters because Liang makes the case that population and youth are the true drivers of the innovation race — that ageing societies risk surrendering their dynamism and, ultimately, their control over AI. Few can argue that thesis from the vantage point of a founder, an economist, and a demographer at onceTIMESTAMPS:0:00 Trailer0:53 Introduction1:29 Why Travel Beat China's Infrastructure Gap3:41 Surviving The Gladiator Economy6:01 Service As The Real Moat10:35 Go Global, Don't Diversify13:36 Why He Quit At The Top For A PhD16:54 Why Only A Founder Could Save It21:15 Working From Home Before COVID25:57 The Innovationism Formula29:31 Why Ageing Kills Innovation32:41 The Exam System That Broke Fertility35:49 Spend Five Per Cent On The Young44:46 What Singapore Keeps Getting Wrong50:16 The Forgotten Case For A Big Family53:56 Why Big Countries Win The Innovation Race56:55 US vs China: Competition Or War?1:00:34 Singapore's One Missing Variable1:03:06 Why AI Makes Innovationism Urgent1:10:36 ClosingThis is the 89th episode Of The Front Row PodcastA huge thank you to our amazing Front Row Friends for supporting and advancing the podcast: @marinama2728@deborahchoi1455@annkowong@yewchoutan5876Full transcripts of episodes can be found here: https://www.ykeith.com/tag/podcast/Feel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected] access to every episode by subscribing for free on Spotify: https://creators.spotify.com/pod/show/keith-yap8 or Apple Podcasts: https://podcasts.apple.com/sg/podcast/front-row/id1771599400

    11 July 2026, 1:39 am
  • 53 minutes 5 seconds
    #88 : Why The US Chip Ban On China Backfired - Robert Wu

    Thank you for checking out The Front Row Podcast and my interview with Robert Wu.

    You can check out his awesome Substack here! https://www.baiguan.news?r=8th0v Robert Wu is the CEO of BigOne Lab, China's leading alternative data and research company, backed by S&P Global and used by institutional investors and corporations around the world to track what is actually happening on the ground in China's economy and tech sector. He is also the founder and co-editor of Baiguan, a data-driven newsletter on Chinese business and markets, and writes China Translated, a personal newsletter offering a practitioner's review of the events shaping China's economy, society, and technology sector


    Wu's career path into China-watching was unconventional: before BigOne Lab, he worked across sourcing, travel, and corporate restructuring in Myanmar, Switzerland, and Hong Kong. He later joined BigOne Lab as an employee and partner before taking it over in a buyout and becoming its CEO. He also writes for the opinion section of The New York Times.Through Baiguan, Wu has organised on-the-ground tours for foreign investors into China's robotics and manufacturing sectors, giving institutional clients direct exposure to the country's AI, EV, and advanced manufacturing ecosystems.


    His work sits at the intersection of data and narrative: translating the granular, often-overlooked detail of China's industrial policy and technology development for an international audience that, in his own words, still has a shockingly low level of understanding of the country driving the most consequential geopolitical shift of the century.In this conversation, Wu draws on years of on-the-ground research to unpack why the US-China tech rivalry is structurally locked in rather than easing, why China's EV industry is the template for understanding its semiconductor and AI ambitions, and what the real bottlenecks are in robotics, chips, and AI monetisation as China's next phase of growth takes shape.This is the 88th episode Of The Front Row PodcastTIMESTAMPS:0:00 Introduction0:31 Has US-China Détente Actually Changed Anything4:15 Did Export Controls Backfire On The US5:25 The Bifurcation Of Tech Ecosystems11:34 The EV Playbook For Industrial Policy12:20 Why Beijing Let Tesla In18:16 The Real Meaning Of Technology Transfer21:03 China's War On Involution25:57 How Chinese Tech Is Going Global31:30 The Manus Deal And The Trust Breakdown32:23 Open Source As China's AI Weapon34:59 The Monetisation Problem36:50 Lessons From The Manus Fallout41:46 Inside China's Robotics Boom47:17 What Foreign Investors Miss About Manufacturing50:26 Advice For The Next Generation52:40 ClosingA huge thank you to our amazing Front Row Friends for supporting and advancing the podcast: @marinama2728@deborahchoi1455@annkowong@yewchoutan5876Full transcripts of episodes can be found here: https://www.ykeith.com/tag/podcast/Feel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected] access to every episode by subscribing for free on Spotify: https://creators.spotify.com/pod/show/keith-yap8 or Apple Podcasts: https://podcasts.apple.com/sg/podcast/front-row/id1771599400

    29 June 2026, 9:46 am
  • 1 hour 2 minutes
    #87- Ex Straits Times Chief Editor on LKY's Ideas, Singapore's Literacy Paradox And Why You Must Read

    Thank you for checking out The Front Row Podcast and my interview with former Chief Editor of Straits Times- Warren Fernandez. Warren Fernandez is a journalist, editor, and public intellectual whose career spans more than three decades at the centre of Singapore's media landscape. He served as Editor-in-Chief of the Straits Times — Singapore's flagship English daily — and is perhaps best known beyond journalism as one of the principal collaborators on several of Lee Kuan Yew's landmark books, including The Man and His Ideas and The Singapore Story. His close working relationship with Mr. Lee gave him an unusually intimate vantage point on Singapore's founding generation and the ideas that shaped the nation's development.After leaving the Straits Times, he served as Edelman's APAC CEO from 2022 to 2025. Fernandez joined the S. Rajaratnam School of International Studies (RSIS), where he is now engaged in research on world order and the shifting dynamics of great power competition. He is also the author of What We Read and Why, an anthology in which leaders, educators, and young people reflect on their relationship with books and reading, making the case for literacy as both a life skill and a civic responsibility.In this conversation, Fernandez draws together threads from an exceptionally varied career: the craft of communicating ideas, the media's role in a small state, the mechanics of world order, and why the capacity to read carefully and think critically has never mattered more.YOUTUBE TIMESTAMPS0:00 Trailer0:00 Introduction0:53 Working on Lee Kuan Yew's Books4:10 LKY as a Force of Nature5:56 The Statesman Behind the Politician6:11 LKY as Communicator6:56 Singapore's Media Model9:03 Journalists and Power10:02 How to Prepare Like a Journalist12:00 LKY's Enduring Ideas13:15 The Transition to Digital Media16:38 The Real Value of Reading18:47 Reading and the Average Citizen21:01 Singapore's Literacy Paradox23:48 Use It or Lose It25:24 Reading as a Life Skill27:32 How to Build a Reading Movement29:46 AI, Sam Bankman-Fried, and the Case for Deep Reading32:15 Reading and Civic Duty34:00 How Top Leaders Read36:57 Young People Do Read38:54 A Masterclass on How to Read Today42:46 Reading and Geopolitics48:01 What Comes Next?49:37 Singapore's Value Proposition52:49 The GX World53:48 Three Imbalances Nobody Is Fixing58:29 Three Books Every Singaporean Should ReadThis is the 87th episode Of The Front Row PodcastA huge thank you to our amazing Front Row Friends for supporting and advancing the podcast: @marinama2728@deborahchoi1455@annkowong@yewchoutan5876Full transcripts of episodes can be found here: https://www.ykeith.com/tag/podcast/Feel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected] access to every episode by subscribing for free on Spotify: https://creators.spotify.com/pod/show/keith-yap8 or Apple Podcasts: https://podcasts.apple.com/sg/podcast/front-row/id1771599400

    13 June 2026, 4:55 am
  • 1 hour 6 minutes
    #86- Ha-Joon Chang : Why We Need A New Global Economic Order

    Thank you for checking out The Front Row Podcast and my interview with Hajoon Chang.


    Ha-Joon Chang is a South Korean economist and one of the most widely read critics of neoliberal orthodoxy working today.

    He is currently a professor of economics at the School of Oriental and African Studies (SOAS).


    He is best known for his book 23 Things They Don't Tell You About Capitalism, published in 2010, which challenged the foundational claims of free-market economics with rigorous historical and empirical argument.


    His earlier work, Kicking Away the Ladder, demonstrated how today's rich countries used protectionism and industrial policy to develop — before turning around and telling developing nations to liberalise.Chang's research spans developmental economics, the history of economic thought, and the political economy of globalisation.


    He has been a vocal proponent of what he calls "non-mainstream" economics: not a single doctrinal school, but a pluralist approach that draws on institutional, Keynesian, and developmentalist traditions to analyse how economies actually grow and change.


    In this conversation, Chang offers a sweeping critique of neoliberalism's track record on growth and inequality, a dispassionate assessment of Donald Trump's industrial policy ambitions, and a pointed analysis of the AI boom as a speculative bubble shaped by concentrated wealth rather than genuine demand.


    TIMESTAMPS:0:00 Trailer

    1:08 Introduction

    1:54 Growing Up in South Korea's Economic Miracle

    4:36 Why Ha-Joon Chang Is Not "Heterodox"

    4:58 The Gwangju Massacre and the Limits of Neoclassical Economics

    10:45 How the Neoliberal Turn Happened

    18:32 The Real Cost of the Free-Market Experiment

    25:20 Why Singapore Works

    29:58 Trump's Industrial Policy: Will It Work?

    37:50 The Three Elements of Good Industrial Policy

    40:54 The Right Lessons From China

    44:44 How Bad Is Inequality in the US?

    53:18 The AI Bubble

    58:36 AI as Public Infrastructure

    1:00:48 How to Build a More Just World

    1:06:14 Closing

    3 June 2026, 9:30 am
  • 34 minutes 40 seconds
    #85- GovTech CTO on The Secret Behind Singapore's World Class Digital Infrastructure

    Thank you for checking out The Front Row Podcast and my interview with Chang Sau Sheong. Sau Sheong Chang is the Chief Technology Officer of GovTech Singapore, the government agency responsible for Singapore's national technology infrastructure and digital public services. In this role, he oversees the development and maintenance of platforms that underpin daily life for millions of Singaporeans — from SingPass, the national digital identity system, to Parents Gateway, CDC vouchers, and the Culture Pass.Sau Sheong brings an unusual combination of deep private-sector experience and long public-service commitment to his work. He began his technology career at the National Computer Board in 1997, left in 1999 to found his first startup, and spent the intervening decades in startups and large technology companies before returning to public service — first as one of the earliest Smart Nation Fellows, and subsequently as a full-time GovTechie.In this conversation, recorded at a community event co-organised by SuperAI, Carta, and Singapore Global Network, Sau Sheong speaks candidly about Singapore's 40-year arc of digital transformation, the buy-versus-build dilemma at the heart of government technology strategy, GovTech's adoption of AI tools including Claude Code for classified systems, and what the AI disruption actually looks like from inside one of the world's most advanced digital governments.TIMESTAMPS:0:00 Introduction1:58 Why Singapore's Digital Edge Isn't an Accident5:45 How GovTech Attracts World-Class Engineers6:33 From Startup Founder to CTO: Sau Sheong's Journey9:44 The Projects Behind Singapore's Digital Infrastructure12:32 Buy vs. Build: The Government's Hardest Dilemma18:39 How GovTech Is Adopting AI19:05 Claude Code for Classified Systems24:54 How GovTech Prioritises AI Deployment Across Agencies28:35 AI Anxiety: Advice for Young Professionals34:13 ClosingThis is the XX episode Of The Front Row PodcastFull transcripts of episodes can be found here: https://www.ykeith.com/tag/podcast/Feel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected] access to every episode by subscribing for free on Spotify: https://creators.spotify.com/pod/show/keith-yap8 or Apple Podcasts: https://podcasts.apple.com/sg/podcast/front-row/id1771599400

    22 May 2026, 9:30 am
  • 1 hour 14 minutes
    #84- Kishore Mahbubani: How The Future Of Global Order Will Look Like

    Kishore Mahbubani is one of Asia's most prominent public intellectuals — a former diplomat, academic, and author whose career spans decades at the intersection of geopolitics, philosophy, and statecraft. He served as Singapore's Permanent Representative to the United Nations on two occasions and as President of the UN Security Council, before becoming the founding Dean of the Lee Kuan Yew School of Public Policy at NUS. He is the author of several widely read books on the shifting global order, most recently Has China Won?

    In this conversation — filmed live in front of an audience of young leaders curated with the National Youth Council — Mahbubani ranges across the Iran-Israel war and the misreading of Persian civilisational logic, the structural weaknesses of multilateral institutions and who is actually responsible for them, the enduring miracle of ASEAN in the world's most diverse region, and the iron law of geopolitics that makes the US-China contest essentially mechanical. He closes with a characteristically optimistic verdict on Singapore's place in history and what the next generation of leaders must understand to navigate the crossfire that is coming.

    Chapters

    0:00 Trailer1:08 Introduction1:42 Singapore's Sixty Years of Peace3:05 The MacDonald House Incident5:00 How Singapore Repaired Relations With Indonesia7:46 The Iran-Israel War8:48 How Israel Sold Trump a Quick War11:27 Why Iran Didn't Surrender12:26 The Strait of Hormuz as a Weapon14:38 Gaza and the Two-State Solution16:00 How Gaza Damaged the West's Standing18:26 Israel's Military Dominance Won't Last Forever21:09 How Young Singaporeans Should Read the Crisis21:42 Don't Get Emotional — Get Rational23:24 Who Actually Weakened the UN24:09 The Hypocrisy of Western Complaints About the UN29:30 How Singapore Can Use Multilateral Platforms31:56 The Iron Law of US-China Competition33:57 How China Found Its Weapon36:02 ASEAN's Imperfections — and Why That's Fine39:37 ASEAN Outgrew the EU42:09 Q&A43:17 The Case for the UN Veto45:15 Why the UK Should Give Its Seat to India47:30 Sunrise vs Sunset Organisations — BRICS and the G752:15 ASEAN's Limits — and Its Quiet Power56:02 The Long-Term Fallout From the Iran War58:20 Is International Law a Sunrise or Sunset Trend?1:02:46 Singapore's Founding Realist Principle1:04:32 The Malacca Toll, the UAE, and the GCC1:09:32 One Piece of Advice for Young Leaders1:10:04 The Singapore Miracle in World History1:13:00 Prepare for the Crossfire1:13:51 Closing

    This is Episode 84 of The Front Row Podcast. Full transcripts are at ykeith.com/tag/podcast/

    Join the conversation in the comments, or find us here:

    Instagram: instagram.com/frontrow.65LinkedIn: linkedin.com/in/keith-yapWebsite: ykeith.comEmail: [email protected]

    20 May 2026, 11:12 am
  • 41 minutes 53 seconds
    #83- Expert Investor : "This Is Southeast Asia's AI Endgame" (Dimitra Taslim)

    Thank you for checking out The Front Row Podcast and my interview with Dimitra Taslim.Dimitra Taslim is seasoned tech investor and currently, serves as a Venture Partner at Granite Asia. Before Granite Asia’s spinout and rebrand from GGV Capital Asia, Dimitra was part of the investment team at GGV Capital, where he helped source and support investments across emerging Asian markets. His work at Granite Asia reflects the firm’s broader thesis of supporting ambitious Asian founders through long-term capital, operational support, and access to cross-border networks.Dimitra brings a blend of investor and operator experience. Prior to venture capital, he worked in private equity and growth investing in London, and also founded a digital wealth startup. His background gives him a strong focus on execution, operational scale, and founder-market fit — especially in businesses solving infrastructure and productivity challenges in Asia.This is the 83rd episode Of The Front Row PodcastFull transcripts of episodes can be found here: https://www.ykeith.com/tag/podcast/Feel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected] access to every episode by subscribing for free on Spotify: https://creators.spotify.com/pod/show/keith-yap8 or Apple Podcasts: https://podcasts.apple.com/sg/podcast/front-row/id1771599400

    12 May 2026, 8:09 am
  • 30 minutes 28 seconds
    #82- NUS Longevity Expert : The AI Revolution in Healthcare Has Arrived

    Dr. Dean Ho is currently Provost’s Chair Professor and Head of the Department of Biomedical Engineering in the College of Design and Engineering, Director of The Institute for Digital Medicine (WisDM) at the Yong Loo Lin School of Medicine, and Director of The N.1 Institute for Health (N.1) at the National University of Singapore.His central argument is that medicine has always been built on population averages — and that this is no longer sufficient. With AI and digital twins, he believes we now have the tools to treat every patient as a sample size of one.The conversation spans three registers: oncology (a blood cancer patient who entered the trial at eighty and is still thriving four and a half years later); commercialised drug combination design (Kyan's 91% predictivity vs a competitor's 52%); and personal healthspan (Dean ran an IRB-approved trial on himself tracking sleep, gut, metabolism, and supplementation).The through-line is a simple but radical idea: a single annual health snapshot tells you almost nothing. Dynamics — how your body changes hour to hour, day to day — is where the signal lives.TIMESTAMPS: 0:00 Introduction1:31 We Are Stories, Not Snapshots4:10 Why Population-Level Medicine Falls Short6:00 The Cancer Patient Who Defied the Odds9:15 Why Lower Doses Can Work Better10:45 Becoming the Test Subject12:00 One Day of Metabolic Data12:40 Sleep, Gut Health & the Delta Trial13:25 Singapore's Edge in Medical Innovation15:23 AI Regulation: The FDA Paradox16:22 What's Broken About the Old System18:12 Scaling N=1: The Real Bottleneck19:48 Why Doctors Resist — and Why They Shouldn't20:40 The Economics of Personalised Treatment21:30 Drug Combinations: 91% Accuracy vs 52%23:20 Advice for Healthy People24:08 Resting Heart Rate as a Sleep Signal27:49 The One Habit Change That Moves the Needle30:00 ClosingFeel free to mingle in the comments below or head to...Instagram: https://www.instagram.com/frontrow.65/Linkedin: https://www.linkedin.com/in/keith-yap/Website: www.ykeith.comEmail: [email protected]

    4 May 2026, 2:59 pm
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