• 58 minutes 17 seconds
    Look for the Signs with Kate Doerge

    On this episode of Living With It, Jamie sits down with Kate Doerge to discuss finding hope after profound loss, recognizing signs from loved ones, and the five actions that can transform the way we move through grief.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    30 July 2026, 5:00 am
  • 1 hour 7 minutes
    Hope Can Exist Alongside Fear with Myriam Sandler

    This week, Jamie sits down with Mothercould creator Myriam Sandler. They discuss her recent MS diagnosis, trusting your intuition, and finding hope even when life doesn't go as planned.


    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

     

    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    OneSkin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod

    CBDistillery - Visit https://CBDistillery.com and use my code MESSY for 25% off. That’s C B Distillery dot com, code MESSY C B Distillery dot com.

    Radiance - For 20% off and FREE SHIPPING. Go to https://BRICKHOUSENUTRITION.com and use code - MESSY


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    28 July 2026, 5:00 am
  • 55 minutes 27 seconds
    It's Okay Not to Be Okay with Amy Kurtz

    On the first episode of Living With It, Jamie sits down with Amy Kurtz, a patient advocate and author. They discuss the grief of chronic illness, learning to trust yourself again, and why healing is about so much more than getting better.

    Novartis in neuroscience

    o Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    23 July 2026, 5:55 pm
  • 48 minutes 29 seconds
    All Eyes on Me

    This week, Jamie reads listener emails and opens up about the feeling of all eyes on you when you're struggling, the anxiety of the lead up, caregiving, and more.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch


    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    CBDistillery - Visit https://CBDistillery.com and use my code MESSY for 25% off. That’s C B Distillery dot com, code MESSY C B Distillery dot com.

    ZocDoc -Head to https://Zocdoc.com/MESSY to get started and check that appointment off your to-do list!

    Radiance -For 20% off and FREE SHIPPING. Go to https://BRICKHOUSENUTRITION.com and use code - MESSY

    Lola Blankets -Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    21 July 2026, 9:03 am
  • 56 minutes 14 seconds
    Tamsen Fadal

    This week, Jamie sits down with journalist, author, and menopause advocate Tamsen Fadal. They discuss the physical and emotional realities of perimenopause, why so many women feel dismissed by the medical system, and how speaking honestly about aging, identity, and women's health can help us all feel less alone.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Veracity - For up to 65% off your order, head to https://VeracityHealth.co and use code MESSY.

    Rythm - Right now, Rythm is offering our listeners 15% off your first month and free shipping at ⁠https://rythm.health/messy⁠ Stop guessing, start testing. Rythm DOT HEALTH slash messy

    Jones Road - Use code MESS at jonesroadbeauty.com to get a Free Gift with your first purchase! #JonesRoadBeauty #ad




    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    14 July 2026, 9:03 am
  • 51 minutes 3 seconds
    You Do Not Have to Become Someone Else to Heal

    This week, Jamie reads listener emails and discusses the invisible weight of living with chronic illness, the courage it takes to keep showing up, and the small moments that can bring us back to ourselves. She also shares the reminder she received from a recent on stage performance.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch


    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Zbiotics - Go to  https://zbiotics.com/MESSY and use MESSY at checkout for 15% off any first time orders of ZBiotics probiotics.

    Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

    Rythm - Right now, Rythm is offering our listeners 15% off your first month and free shipping at https://rythm.health/messy   Stop guessing, start testing. Rythm DOT HEALTH slash messy 


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    7 July 2026, 9:20 am
  • 1 hour 2 minutes
    Erin Moriarty

    This week, Jamie sits down with Erin Moriarty. They discuss Erin's journey with Graves' disease while starring in "The Boys," the invisible toll chronic illnesses can take on your mental health, learning to advocate for yourself, and why vulnerability may be the greatest form of strength.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch


    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Jones Road - Use code MESS at jonesroadbeauty.com to get a Free Gift with your first purchase! #JonesRoadBeauty #ad

    MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at  https://mudwtr.com/MESSY  #mudwtrpod
    Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    30 June 2026, 9:03 am
  • 50 minutes 49 seconds
    Mia Calabrese

    This week, Jamie is joined by Summer House’s Mia Calabrese. She opens up about her journey with grief and what’s helped her to find joy again. They also discuss the Summer House scandal and Mia shares her thoughts on the reunion and bonus episode.


    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch


    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    ZocDoc - Stop putting off those doctors appointments and go to https://Zocdoc.com/MESSY to find and instantly book a doctor you love today. 

    MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at  https://mudwtr.com/MESSY  #mudwtrpod
    OneSkin - Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/MESSY #oneskinpod



    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    23 June 2026, 9:03 am
  • 49 minutes 19 seconds
    Choose Yourself

    This week, Jamie reads emails from listeners. She also discusses mom guilt, PMS and MS, letting people know how their actions affect you, and much more. 

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch

    This episode is sponsored by:

    Novartis in neuroscience Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Q30 - For a FREE sleeve with your order, head to https://Q30.com/MESSY and use code MESSY.

    Lola - Get 40% off select Lola Blankets products at https://Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

    Veracity- For up to 65% off your order, head to https://VeracityHealth.co and use code MESSY.  

    K18- Shop at Sephora or get 10% off your first purchase at https://k18hair.com with code MESSY. That’s code MESSY at k18hair.com




    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    16 June 2026, 9:03 am
  • 1 hour 3 minutes
    Our Favorite Bravo Men

    This week, we are revisiting conversations with some of our favorite Bravo men - Jesse Solomon, Carl Radke, and Andy Cohen. They share moments that were challenging, helped them grow, and changed their perspectives on life. 


    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch


    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.

    Jones Road - Use code MESS at jonesroadbeauty.com to get a Free Gift with your first purchase! #JonesRoadBeauty #ad

    Rythm - Right now, Rythm is offering our listeners 15% off your first month and free shipping at https://rythm.health/messy   Stop guessing, start testing. Rythm DOT HEALTH slash messy 

    NOCD - If you're struggling with OCD or unrelenting intrusive thoughts, NOCD can help. Book a free 15 minute call to get started  https://learn.nocd.com/messy


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    9 June 2026, 9:03 am
  • 55 minutes 11 seconds
    Aida Turturro

    This week, Jamie sits down with the one and only Aida Turturro. They reflect on their years together on The Sopranos, and Aida discusses living with rheumatoid arthritis since childhood, perspective, and finding gratitude during difficult times.

    Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick

    Audio Engineer: Josh Windisch


    This episode is sponsored by:

    Novartis in neuroscience - Our ambition is to create a transformational impact for people living with severe neurological conditions and their caregivers by discovering, developing and delivering innovative medicines that change the course of disease progression.


    Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod

    Q30 - For a FREE sleeve with your order, head to https://Q30.com/MESSY and use code MESSY. 
    Ridge - Upgrade your wallet today! Get up to 40% off @Ridge during their Father’s Day Sale when you go to https://www.Ridge.com/MESSY  #Ridgepod


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    2 June 2026, 9:03 am
  • More Episodes? Get the App