2 Chainz has never been afraid to bet on himself. He opens up to Keke about getting arrested in high school, the teachers who believed in him, and later buying himself out of his record deal with Ludacris and building on his success. He and Keke bond over raising boys as he shares what he loves about doing the Me & Halo podcast with his son. Plus, they get into young rappers, the faith behind his bestselling memoir The Voice in My Head Is God, and his new album Players Only Live Once.

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Chef Kwame Onwuachi joins Keke and shares how watching Barack Obama succeed inspired him to change the course of his life after getting into trouble as a young man. He traces his journey from the Bronx and Nigeria to Top Chef, reflecting on failure, finding his voice through food and building Tatiana into one of NYC’s hottest restaurants. Plus, he talks cooking at the Met Gala and teaches Keke a recipe from his new cookbook, All Hours: Crazy Good Food for Whatever, Whenever.

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Octavia Spencer jokes that she was an “overnight success” 15 years in the making. She and Keke discuss the friends and mentors who shaped her, from Melissa McCarthy to Whoopi Goldberg, plus her sister hanging up on Patrick Swayze. She shares how she trusted herself and defied Hollywood after her Oscar win for The Help and now produces and stars in her own projects, including Amazon Prime’s hit series Ride or Die, opening doors for others. She revisits that iconic Ma bob in a hilarious game.

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Tommy Davidson’s story starts long before In Living Color. He opens up to Keke about being abandoned as a baby, growing up Black in a white adoptive family and how it shaped his identity and comedy. He reveals how a tragedy at one of his stand-up shows taught him the power of laughter and explains why he apologized to Dionne Warwick. Plus, Tommy sings, breaks out his legendary impressions and shares why his dream of playing Sammy Davis Jr. in a movie may finally come true.

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Laverne Cox opens up about her memoir Transcendent, childhood trauma, finding self-acceptance and the challenges she still faces today. She gets real about dating conservative men, dating-app disasters, a famous rapper who had to work for her number and why she’s been celibate for two years. Plus, Laverne looks back at Orange Is the New Black, fighting for trans rights and what’s changed for trans visibility since the hit show ended.

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Jamie Foxx and his daughter Corinne share incredible stories with Keke and celebrate Beat Shazam’s 100th episode. Jamie breaks out his hilarious impressions, revisits his greatest hits from In Living Color and Django Unchained to how Oprah kept his Oscar run for Ray on track. In an emotional moment, they revisit his stroke and why he credits Corinne with saving his life. Plus, a birthday surprise for Keke brings her to tears.

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Drew Afualo opens up about writing her bestselling book, LOUD, the darker side of TikTok fame, her podcasts The Comment Section and Two Idiot Girls, and her Samoan culture and family. Drew gets real about questioning the rules women are taught to follow, why they don’t always have to be nice, and how her fiancé, Pili, won her heart. Plus, Drew’s hot takes on dating, Love Island, Chappell Roan, and her full-circle moment with The Rock, and why she went to bat for Keke online before they met.

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Yvette Nicole Brown and Keke reunite for a heartfelt conversation filled with laughs, memories, and surprises. Yvette opens up about marrying at 53, caring for her father through Alzheimer’s, speaking up for what she believes in, and whether a Community movie is finally happening. They revisit Drake & Josh, relive their viral Password “Titanic” moment, and Lady Miss Jacqueline makes a surprise appearance to celebrate their new Audible series, The Weddings of Lady Miss Jacqueline.

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Whoopi Goldberg has spent her career turning “no” into opportunity. She tells Keke how she created the groundbreaking one-woman show that inspired today’s The Whoopi Monologues when no one would hire her, landed Ghost after Patrick Swayze stepped in, and became an icon by redefining what Hollywood thought was possible. She also opens up about why marriage isn’t for her, asking for what you’re worth, speaking her mind on The View, and why every woman needs her own “hell with it” money.

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FLO is here, and this one’s for the fans. Jorja, Renée, and Stella get into the story behind “Cardboard Box,” the PowerPoint that convinced their label to release it, and how Therapy at the Club turns heartbreak, healing, and girls’ nights into nonstop bops. They also get candid about dating, dream collaborations, and girl group legacy, with plenty of laughs along the way. Then Keke tests their knowledge in “Name That Girl Group Hit” and joins FLO as the honorary fourth member for a sing-along.

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Oprah Winfrey sits down with Keke for a personal, uplifting, and honest conversation about the life she built, the freedom she earned, and the meaningful moments she’s sharing on The Oprah Podcast. Oprah opens up about what the man troubles in her 20s taught her about love, the Maya Angelou advice that helped her handle criticism, and why she and Gayle King are total opposites after 50 years of friendship. Plus, she shares powerful advice and gems on self-worth, success, and Black womanhood that move Keke to tears.

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