• 1 hour 43 minutes
    Opus 4.8 Beats GPT 5.5, the $220B OpenAI Foundation, and Hassabis’s 2029 AGI Prediction | EP #260

    In this episode, the mates discuss Opus 4.8, The OpenAI Foundation, Demis Hassabis' views on AGI, AI extremism on the rise, and more.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Salim Ismail is the founder of Open ExO, a GP at Exponential Venture Capital/The Organizational Singularity Fund and a sought after global speaker and thought leader.


    Dave Blundin is the founder & GP of Link Ventures


    Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified

    My companies:

    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 

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    *Recorded on May 30th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

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    1 June 2026, 9:15 pm
  • 1 hour 48 minutes
    Pope Leo vs. AI, GPT 5.5 Beats Claude, and Sam Altman Walks Back Job Apocalypse | EP #259

    This episode is a sprawling Moonshots roundup with three big pillars: AI governance and religion, AI’s impact on jobs and entrepreneurship, and a moon/space-compute future centered on SpaceX, Starlink, and Tesla.


    Education survey: Moonshots.com/survey


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Salim Ismail is the founder of Open ExO, a GP at Exponential Venture Capital/The Organizational Singularity Fund and a sought after global speaker and thought leader.


    Apply for Salim’s Pilot Program: https://openexo.com/organizational-singularity-pilot?video=I9c8STV7Hnw


    Dave Blundin is the founder & GP of Link Ventures


    Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified


    My companies:

    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


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    Subscribe to Salim’s YouTube channel

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    Resources: https://openexo.com/resource-hub 


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    *Recorded on May 28th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

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    30 May 2026, 4:27 pm
  • 1 hour 2 minutes
    The Organizational Singularity: AI-Proof Your Company | EP #258

    This episode is a deep dive on the “organizational singularity”: how AI agents, AI-native workflows, and recursive self-improvement will restructure companies much faster than traditional hierarchy can adapt.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Salim Ismail is the founder of Open ExO, a GP at Exponential Venture Capital/The Organizational Singularity Fund and a sought after global speaker and thought leader.


    Apply for Salims Pilot Program


    My companies:

    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


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    Exponential Venture Capital



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    *Recorded on May 16th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    26 May 2026, 4:40 pm
  • 1 hour 52 minutes
    SpaceX’ $75B+ Historic IPO, GPT 5.5 Outperforms Polymarket, and AI Solves 80 yr old math problem | EP #257

    In this episode, the Moonshot mates discuss SpaceX's record-breaking IPO filing and its growing ties to Anthropic, OpenAI's AI model disproving a decades-old Erdős conjecture in mathematics, and GPT-5.5 beating prediction markets at forecasting.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Salim Ismail is the founder of OpenExO


    Dave Blundin is the founder & GP of Link Ventures


    Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified


    Apply for Salim’s Pilot Program: https://openexo.com/organizational-singularity-pilot?podcast=23.5.26


    Subscribe to Salim’s channel: https://www.youtube.com/@salimismail



    – My companies:

    Apply to Dave's and my new fund: ⁠https://qr.diamandis.com/linkventures...⁠

    Go to Blitzy to book a free demo and start building today: ⁠https://qr.diamandis.com/blitzy⁠

    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: ⁠https://www.fountainlife.com/peter⁠


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    *Recorded on May 21st, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.


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    23 May 2026, 7:00 pm
  • 2 hours 24 minutes
    Google I/O 2026, Karpathy Joins Anthropic, and Cerebras’ $95B IPO | EP #256

    In this episode, the mates welcome Andrew Feldman, Co-founder and CEO of Cerebras Systems, and discuss several tech news such as Google’s I/O comeback, the jury verdict in Elon Musk’s OpenAI lawsuit, Anthropic’s accelerating enterprise momentum, and a long interview with Andrew Feldman of Cerebras after its major IPO.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Andrew Feldman is the Co-founder and CEO of Cerebras Systems.


    Salim Ismail is the founder of OpenExO


    Dave Blundin is the founder & GP of Link Ventures


    Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified


    -


    My companies:

    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


    _


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    Pre-order Salim’s new book: shapingluck.com


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    *Recorded on May 20th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    21 May 2026, 9:37 pm
  • 2 hours 11 minutes
    Anthropic Partners With SpaceX AI, Leopold's $5.5B Bet, and the Singularity Economy | EP #255

    This episode is a dense AI-and-abundance conversation about Anthropic’s explosive growth, compute shortages, SpaceX becoming a hyperscaler, Google’s orbital data-center ambitions, OpenAI’s super-app strategy, Claude’s legal and small-business “unhobbling,” and a long segment on UAP/UFO disclosure. It also weaves in alignment, privacy, AI personhood, and the idea that the singularity may become visible in space before it does on Earth.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Salim Ismail is the founder of OpenExO


    Dave Blundin is the founder & GP of Link Ventures


    Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified


    My companies:


    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


    _


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    *Recorded on May 14th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    16 May 2026, 3:00 pm
  • 2 hours 8 minutes
    Google's Record Quarter, the White House Intervenes, and GPT 5.5 Silently Matches Mythos | EP 254

    In this episode, the mates welcome Blitzy CEO Brian Elliott to discuss Google’s blowout AI-driven earnings, White House model vetting, Pentagon deals with frontier labs, compute scarcity, the rise of private-equity-led enterprise AI, ocean and space data centers, OpenAI’s changing cloud strategy and delayed IPO talk, AGI definitions, AI risk/insurance, and the growing role of AI in GDP and infrastructure.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Brian Elliott, Co-Founder and CEO of Blitzy.

    Learn about Blitzy AI


    Salim Ismail is the founder of OpenExO


    Dave Blundin is the founder & GP of Link Ventures


    Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified


    My companies:


    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


    _


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    *Recorded on May 6th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    9 May 2026, 3:00 pm
  • 1 hour 34 minutes
    Demis Hassabis on AGI, Robots Scale Production, and Elon’s $1T Mars-Shot Comp | EP #253

    This episode features a dynamic panel discussion on exponential technologies, AI advancements, robotics, and the future of humanity. Experts explore the implications of AI, robotics, biotech, and societal shifts, offering insights into what the next decade holds for innovation and civilization.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Steven Kotler is a New York Times bestselling author, and founder of the Flow Research Collective and Flow Institute, known for his work on flow and human performance.


    Salim Ismail is the founder of OpenExO


    Dave Blundin is the founder & GP of Link Ventures


    Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified


    My companies:


    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


    _

    Connect with Peter:

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    *Recorded on May 4th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    7 May 2026, 8:00 pm
  • 2 hours 19 minutes
    Google Invests $40B Into Anthropic, GPT 5.5 Drops, and Google Cloud Dominates | EP #252

    In this episode, the mates explore the rapid advancements in AI, the global AI race, new models like Kimi K 2.6 and GPT 5.5, and the implications for privacy, security, and the future of technology. The mates discuss the future of work, AI regulation, and transformative biomedical breakthroughs.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    Salim Ismail is the founder of OpenExO


    Dave Blundin is the founder & GP of Link Ventures


    Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified


    My companies:


    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


    _


    Connect with Peter:

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    Connect with Alex

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    Listen to MOONSHOTS:

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    *Recorded on April 28th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    4 May 2026, 12:03 pm
  • 27 minutes 4 seconds
    David Sinclair: The GLP-1 Side Effect No One Talks About, What AI Found in His Lab, and Reversing Blindness | Q&A EP #251

    This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/


    This Q&A is about longevity, and especially how David Sinclair sees AI speeding up drug discovery, biological-age reversal, and the future of healthspan. It also covers GLP-1s, telomeres, genetics, muscle preservation, hormone replacement, indoor environment, and the role of mindset in aging well.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    David A. Sinclair, A.O., Ph.D., is a tenured Professor of Genetics at Harvard Medical School and a serial biotech entrepreneur. Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    My companies:


    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


    _

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    Listen to MOONSHOTS:

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    *Recorded on March 9th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    28 April 2026, 3:00 pm
  • 32 minutes 32 seconds
    David Sinclair on the Longevity Pill, Age Reversal Timelines, and Updated Protocols | EP #250

    This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/


    In this insightful interview, Dr. David Sinclair discusses groundbreaking advancements in longevity research, including epigenetic reprogramming trials, the potential for extending human lifespan, and accessible therapies. He shares his personal protocols and the future of anti-aging science, emphasizing the importance of innovation and community support.


    Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends  


    David A. Sinclair, A.O., Ph.D., is a tenured Professor of Genetics at Harvard Medical School and a serial biotech entrepreneur. 


    Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360


    My companies:


    Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding  

      

    Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy  


    Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter 


    _

    Connect with Peter:

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    Listen to MOONSHOTS:

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    *Recorded on March 9th, 2026

    *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice.

    Learn more about your ad choices. Visit megaphone.fm/adchoices

    27 April 2026, 3:00 pm
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