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In this episode, Gabrielle Lyon sits down with Leila Hormozi to discuss the journey from grit to empathy in both personal and professional life. Leila shares candid stories of building her first business, the sacrifices involved, and how her experiences in fitness shaped her entrepreneurial mindset. The conversation explores the value of failure, the importance of discipline, and what it truly takes to achieve business success, reflecting on the unique challenges and rewards that women encounter in leadership roles.

Gabrielle and Leila also open up about balancing ambition, relationships, and personal well-being. They address how to build trust, practice self-belief, and handle the pressures of being public figures with authenticity. You will find practical insights on navigating discomfort, the importance of continuous growth, and on creating a fulfilling life based on clear priorities and honest reflection. The episode is filled with relatable stories and actionable advice for anyone focused on self-development and leadership.

Chapters:

0:00 – From Grit to Empathy: How Leila’s Perspective Shifted

1:33 – Why Fitness Built the Foundation for Business Success

3:38 – Confidence, Self-Belief, and the Difference Between Rookie and Seasoned Entrepreneurs

8:23 – Discomfort, Anxiety, and Paying the Price for Growth

12:58 – Becoming Public-Facing and Outgrowing the Persona You Created

16:01 – Creating Content Without a Funnel or Ego-Driven Motives

19:32 – Why Fewer Women Teach Business at Scale

22:42 – What Actually Makes a Business Legitimate

24:23 – Trust, Relationships, and Learning to Trust Yourself

26:38 – Success vs Happiness and the Tradeoffs People Ignore

31:56 – Sacrifice by Season: Constraints, Focus, and Capacity

35:14 – Personal Trade-Offs and the Real Cost of Success

36:50 – Growth Levels Are About Exposure, Not Time

37:25 – Why You Should Stress Yourself Out More (Short-Term)

43:04 – Social Media, Authenticity, and Being Fully Human

46:15 – Reading Psychology and Understanding Culture

48:19 – Maintaining Relationships Between High Achievers

54:19 – Renegotiating Relationship Roles as Life Evolves

59:54 – Belief Is an Output, Not an Input

1:04:07 – Changing Your Relationship With Discomfort

1:04:55 – What’s Next: Expansion, Health, and Long-Term Vision

Thank you to our sponsors:

1. OneSkin - Get 15% off at https://www.oneskin.co/ with code DRLYON
2. BodyHealth - Get 20% off your first order with code LYON20 https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/
3. Bon Charge - Save 15% at https://boncharge.com/ with code DRLYON

Find Leila Hormozi at:

1. IG: https://www.instagram.com/leilahormozi/
2. YouTube: https://www.youtube.com/@leilahormozi

Find Dr. Gabrielle Lyon at:

1. Instagram: @drgabriellelyon
2. TikTok: @drgabriellelyon
3. Facebook: facebook.com/doctorgabriellelyon
4. YouTube: youtube.com/@DrGabrielleLyon
5. X (Twitter): x.com/drgabriellelyon
6. Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
7. Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

This episode includes paid sponsorships.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

In this episode, Dr. Gabrielle Lyon is joined by Sohee Carpenter, PhD, to explore the complex intersection of psychology, eating behavior, and resistance training. Dr. Carpenter shares her personal journey from struggling with eating disorders to becoming a leading expert in sports science, offering a unique perspective on why high achievers often struggle with diet adherence.

They dive deep into the science of behavior change, emphasizing that willpower is a finite resource and that true success lies in building automatic, cognitively effortless habits. Dr. Carpenter debunks common fitness myths, including the necessity of "lifting heavy" and the supposed ineffectiveness of circuit training, while providing practical strategies like "habit stacking" and "designing for laziness" to help listeners navigate their own health journeys.

Chapter Markers

- 0:00 - Intro: The finite nature of exercise vs. the 24/7 challenge of nutrition.

- 1:22 - Meet Sohee Carpenter, PhD: Her academic journey from Stanford Biology to a PhD in Sports Science.

- 4:33 - Personal Struggles: Overcoming anorexia, bulimia, and long-term binge eating.

- 5:41 - Cultural Pressures: Growing up with the beauty standards of Korea vs. the US.

- 8:38 - The Fitness Hobbyist: Discovering weights and the "clean eating" trap in 2011.

- 13:10 - The Career Pivot: Choosing Psychology and Fitness over Medical School.

- 17:52 - The Binge-Restrict Cycle: Why trying "harder" and being stricter backfires.

- 21:54 - Defining RMR: Understanding Resting Metabolic Rate as your caloric floor.

- 29:26 - Binge Eating Triggers: Emotion regulation and poor stress coping mechanisms.

- 33:10 - The Freedom of No "Food Noise": Intuitive eating as a learned skill.

- 36:08 - Gentle Nutrition: The "Add, Don’t Restrict" mindset.

- 38:46 - The Willpower Battery: Why habits are superior to brute force discipline.

- 45:47 - Habits and Environment: How to "Design for Laziness".

- 50:00 - Habit Stacking: Pairing new behaviors with existing daily rituals.

- 55:04 - Last Chance Syndrome: The logic of a binge and the "all or nothing" mentality.

- 1:00:13 - Cognitive Distortions: Catastrophizing and the "bird's eye view" reframe.

- 1:04:36 - Dichotomous Thinking: Why black-and-white mindsets lead to binging.

- 1:06:48 - Intrinsic vs. Extrinsic Motivation: Finding a "why" that lasts.

- 1:12:34 - Identity Change: Perceiving yourself as the person you want to become.

- 1:14:27 - Resistance Training for Women: Determining the ideal frequency and style.

- 1:19:16 - National Muscle Health Month: Elevating muscle as a pillar of health.

- 1:21:39 - The "Heavy Lifting" Myth: Using rep ranges and reps in reserve (RIR).

- 1:26:13 - The Circuit Training Study: Similar muscle gains in 25 minutes less time.

- 1:29:44 - Training Fasted: Dispelling misconceptions for women’s metabolic health.

- 1:30:57 - Running while Pregnant: Staying capable and medically cleared.

- 1:33:34 - Final Takeaways: Incremental change and a holistic view of health.

Thank you to our sponsors:

Four Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee (just pay for shipping & handling).

Cozy Earth - Go to https://www.cozyearth.com/DRLYON for up to 20% off!

Our Place - Visit https://www.fromourplace.com/DRLYON and use code DRLYON for 10% off sitewide.

Find Sohee Carpenter at:

- IG: https://www.instagram.com/soheefit

- Youtube: @SoheeFit

Find Dr. Gabrielle Lyon at:

- Instagram:@drgabriellelyon

- TikTok: @drgabriellelyon

- Facebook: facebook.com/doctorgabriellelyon

- YouTube: youtube.com/@DrGabrielleLyon

- X (Twitter): x.com/drgabriellelyon

- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/

- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page

- Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions. This episode includes paid sponsorships.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

Are your immune cells aging faster than you are? In this episode, Dr. Gabrielle Lyon sits down with Dr. Anurag Singh, a leading physician-researcher and Chief Medical Officer at Timeline, to discuss a groundbreaking discovery: the gut-muscle-immune axis.

While we often focus on muscle mass for longevity, new research published in Nature Aging reveals that our immune system undergoes a similar decline, with youthful sentinel cells (naive CD8 T-cells) dropping by 75% as we reach age 50.

Dr. Singh explains how mitophagy —the targeted recycling of damaged mitochondria—is the key to "rewiring" an aging immune system to fight infection 20% more effectively. In this episode: Alzheimer’s of the Muscle: Why sporadic inclusion body myositis (sIBM) is often misdiagnosed as simple aging.

The Power of Urolithin A: How this postbiotic compound induces mitophagy to increase mitochondrial abundance by 20% in just 28 days. Immune Imprinting: Why children get 6-8 colds a year while adults only average 2-4. Repurposing Longevity Drugs: Dr. Singh’s take on Metformin, Rapamycin, and GLP-1s for life extension. The 1:1 Exercise Rule:Why 150 minutes of moderate activity is the threshold for mitochondrial biogenesis.

Thank you to our sponsors:

BodyHealth - Use the code LYON 20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/

Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyon

Manukora - Go to https://www.MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.

Chapters:

0:00 - Can You Tell If Your Immune System Is Healthy?

1:37 - Alzheimer’s of the Muscle: Muscle-Immune Dysfunction

5:59 - The Thymus Design Flaw: Why Our Immune "Ammo" Disappears

8:44 - Naive CD8 T-Cells: The Elite Forces of Immunity

12:24 - The Axis of Aging: Mitochondria and Immune Cells in Muscle

16:15 - Mitophagy vs. Autophagy: Targeted Cellular Recycling

19:11 - Study Review: Rewiring the Immune System with Urolithin A

24:13 - Mitochondrial Remodeling: Switching from Glucose to Fatty Acids

27:45 - The Trifecta: Gut-Muscle-Immune Axis Connection

31:13 - Parkinson’s and the PINK1/Parkin Mitophagy Pathway

35:04 - Clinical Results: Improving Leg Strength in 4 Months

38:51 - Joint Health: Can We Remodel Cartilage with Mitophagy?

43:34 - Targeted Mitophagy Inducers: Exercise vs. Postbiotics

46:44 - Precision Nutrition: The Ideal Muscle Longevity Supplement

53:33 - Why Alzheimer’s is Now Considered an Inflammatory Disease

1:00:13 - The Placebo Effect: You Cannot Deceive the Immune System

1:03:13 - Lymphocyte Counts: The Clinical Marker for Immune Aging

1:08:14 - Rapamycin and Metformin: The Future of Longevity Drugs

1:11:42 - Optimal Dosing: Why 1,000mg of Urolithin A is the Standard

1:15:13 - Sports Medicine: Reducing Muscle Damage Markers (Creatine Kinase)

1:20:03 - The Final Frontier: Brain Aging and Selenium Repair

Connect with Dr. Anurag Singh

Instagram: @timeline_longevity

Website: https://www.timeline.com

Find Dr. Gabrielle Lyon at:

1. Instagram:@drgabriellelyon
2. TikTok: @drgabriellelyon
3. Facebook: facebook.com/doctorgabriellelyon
4. YouTube: youtube.com/@DrGabrielleLyon
5. X (Twitter): x.com/drgabriellelyon
6. Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
7. Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
8. Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

Disclaimers: This episode includes paid sponsorships.

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

If you are only focusing on building muscle, you are missing half the equation for long-term mobility. In this mashup episode, Dr. Gabrielle Lyon brings together top orthopedic experts to discuss the critical importance of joint and tendon health.

While muscle develops relatively quickly, your tendons and ligaments can take 6 to 9 months to fully adapt to a new training stimulus. This gap is where most injuries happen. We dive deep into the biological mechanics of tendons, the"athletic accommodation timeline," and why you must progressively overload your connective tissue—not just your muscle bellies.

You will learn:

1. The Menopause Connection: Why women face a 30% higher risk of arthritis and rapid bone loss after age 50, and the role of estrogen in joint inflammation.
2. Osteoporosis Prevention: Why high-impact "flight" exercises (jumping) are more effective for bone density than traditional lifting alone.
3. The Frozen Shoulder Mystery: How to identify the warning signs and why this condition is often linked to hormonal shifts rather than trauma.
4. Injury Recovery & Prehab: The truth about PRP, needle tenotomy, and the "anti-fragility" mindset needed to build a resilient body.
5. The History of Muscle: How ancient Greek views of "pneuma" and the "gift of strength" shaped our modern misunderstanding of movement.

Stop training until you break. Learn how to track your progress, prioritize stability over raw mobility, and design a life built for anti-fragility.

0:00 - The Gap Between Muscle and Tendon Adaptation

1:32 - What Are Tendons? Visco-Elasticity and Force Dissipation

4:36 - The Rotator Cuff: Stabilizing the "Golf Ball on a Tee" 6:40 - The Athletic Accommodation Timeline: Why 6-9 Months Matters

8:36 - Progressive Overload for Connective Tissue, Not Just Muscle

11:36 - GLP-1s and Bone Health: Does Ozempic Increase Fracture Risk?

14:34 - Preventing Osteoporosis: The Power of Impact Training

18:15 - Bisphosphonates vs. Mechanical Loading for Bone Quality

21:10 - The Hidden History of Muscle: From Galen to Ancient Greece

26:48 - The Myth of "Pneuma" and the Soul in the Muscle

30:55 - Supercompensation: The "Gift from Zeus" in Performance

36:35 - Defining Impact Exercise: Why "Flight" is Better for Bones

39:48 - Building Your Base: Why Bone Health is Won Before Age 30

42:38 - Oral Contraceptives and Peroperative Blood Clot Risks

45:21 - The Hard Truth: How Nicotine Destroys Orthopedic Healing

47:55 - Testosterone and Muscle Mass vs. Bone Density in Women

51:41 - Relative Energy Deficiency in Sport (RED-s) and Stress Fractures

55:53 - Long-Term Menopause Consequences: Mobility and Hip Fractures

1:01:58 - Tendinopathy Treatments: Needle Tenotomy, 10X, and PRP

1:07:26 - Full Thickness vs. Incomplete Tendon Tears

1:12:05 - Prehab is Real: The Push-Up with a Plus and Skater Squats

1:13:58 - The Biomechanics of the Gate Cycle & Pelvic Stability

1:17:31 - Medications that Destroy Tendons: Fluoroquinolones & Statins

1:20:02 - Corticosteroids: Balancing Short-Term Relief with Repair Issues

1:24:12 - Nutrition for Joint Health: Collagen, Vitamin C, and Leucine

1:27:11 - Thyroid and Sex Hormone Influence on Tendon Metabolism 1:31:50 - The "Menopause Arthritis" Phenomenon

1:54:04 - Mobility vs. Stability: The 2x2 Evaluation Table

2:11:06 - Zone 2 vs. HIIT: Raising the Ceiling of Human Performance

2:24:21 - Anti-Fragility: Using Stressors to Get Stronger

Thank you to our sponsors:

1. PaleoValley - Get 15% off automatically at https://paleovalley.com/DRLYON
2. OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.co
3. Branch Basics - 15% off and free shipping on the Starter Kit when you use code DRLYON at BranchBasics.com/DRLYON
4. PIQUE - Get 20% off for life + a complimentary gift Piquelife.com/DRLYON

Find Dr. Jocelyn Wittstein at:

Duke Health - https://www.dukehealth.org/find-docto...

Instagram - @jocelyn_wittstein_md

The Complete Bone and Joint Health Plan - Find it at Amazon and Barnes & Noble

Find Gerard D'Onofrio, MD

Web: https://www.summithealth.com/doctors/provider/1376049130

LinkedIn: linkedin.com/in/gerarddonofrio27

Find Dr. Gabrielle Lyon at:

1. Instagram:@drgabriellelyon
2. TikTok: @drgabriellelyon
3. Facebook: facebook.com/doctorgabriellelyon
4. YouTube: youtube.com/@DrGabrielleLyon
5. X (Twitter): x.com/drgabriellelyon
6. Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
7. Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
8. Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

Disclaimers: This episode includes paid sponsorships.

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

Thank you to our sponsors:

1. BodyHealth - Use the code LYON20 to get 20% off your first order https://bodyhealth.com/
2. Manukora - Visit MANUKORA.com/DRLYON to save 31% plus $25 worth of free gifts.
3. BON CHARGE - Holiday Sale https://boncharge.com for 25% off
4. Our Place - Visit fromourplace.com/DRLYON and use code DRLYON for 10% off

Find Dr. Gabrielle Lyon at:

1. Instagram:@drgabriellelyon
2. TikTok: @drgabriellelyon
3. Facebook: facebook.com/doctorgabriellelyon
4. YouTube: youtube.com/@DrGabrielleLyon
5. X (Twitter): x.com/drgabriellelyon
6. Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
7. Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
8. Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

Disclaimers: This episode includes paid sponsorships.

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Timestamps:

0:00 - FDA Lifts Blackbox Warning on HRT

1:08 - Definitions: Viralization & Androgens

3:08 - The New Landscape of Women's Health

4:46 - Gold Standard Testing: Mass-Spec

5:52 - Finding the Estrogen Sweet Spot for Men

8:07 - Testosterone Lab Ranges for Women

10:16 - Is Testosterone Safe for Women?

13:30 - Anabolic vs. Androgenic Steroids

16:56 - HRT Red Flags: Who Should Not Start

18:19 - Longevity Benefits of HRT

21:23 - Estrogen's Role in Brain Health

24:32 - Performance Impact in Young Women

33:03 - Type 2 Muscle Hypertrophy

37:06 - Monitoring Hematocrit & Safety

41:44 - Delivery: Injections vs. Gels

42:31 - How TRT Can Mask Anemia

46:36 - Impact on Cholesterol & Lipids

51:48 - Non-Negotiable Baseline Lab Panels

53:23 - Case Study: 60-Year-Old Transformation

58:15 - The Future of FDA Approval

59:06 - Can DHEA Move the Needle?

If you or someone you know is experiencing suicidal thoughts, emotional distress, or a mental health crisis, call or text 988, or chat via 988lifeline.org.

Support is available 24/7. You are not alone, and help is available.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

Dr. Gabrielle Lyon sits down with renowned medical correspondent and OB/GYN, Dr. Jen Ashton, for a profoundly personal and candid conversation about navigating life's most intense tragedies while maintaining a public career.

Dr. Ashton bravely opens up about the devastating suicide of her first husband, a world-class surgeon, 18 days after their divorce was finalized. She shares the raw reality of being in clinical shock and how the immense tragedy became an unexpected catalyst for post-traumatic growth.

Dr. Ashton, who holds a Master's degree in Nutritional Sciences, also brings her medical expertise to current health debates:

• The Power of Fitness: Learn how resistance training became Dr. Ashton's lifeline to snap her out of emotional numbness and shock.
• The Hormone Misinformation Crisis: They discuss the flawed data and flawed media that led to 20 years of women being under-treated for menopause after the Women's Health Initiative (WHI).
• GLP-1 Myths: Dr. Ashton breaks down the top myths surrounding GLP-1 medications, the difference between absolute vs. relative risk, and the non-weight related benefits that are just beginning to emerge.
• The Problem with Extremes: They address the societal tendency to seek out quick-fix solutions in health, menopause, and obesity care, arguing that the true sweet spot is in a nuanced, moderate position.
• Finding Love Again: Dr. Ashton shares the unexpected miracle of finding profound love with her current husband, legendary sports executive and TV producer, Tom Werner.

About Jen Ashton: Retiring stiff paper gowns and unrelatable medical advice, Dr. Jennifer Ashton, a Board-certified Ob-Gyn, author, and TV medical correspondent, breaks the barrier between doctor and patient. Affectionately referred to as your all-in-one ‘BFF’/Ob-Gyn, Dr. Jennifer Ashton marries an unparalleled medical background with an accessible‘girl’s-girl’ attitude. Though Dr. Ashton can easily speak to the latest beauty and fashion trends, this Ivy League graduate means business when it comes to women’s health.

Thank you to our sponsors: 

• Timeline - Get 20% off your order at https://timeline.com/LYON 
• OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.co

Find Jen Ashton at: 

• Book: Life After Suicide - https://a.co/d/0HvOeSH
• IG: https://www.instagram.com/drjashton
• Web: https://www.joinajenda.com

Find Dr. Gabrielle Lyon at: 

• Instagram:@drgabriellelyon 
• TikTok: @drgabriellelyon
• Facebook: facebook.com/doctorgabriellelyon
• YouTube: youtube.com/@DrGabrielleLyon
• X (Twitter): x.com/drgabriellelyon
• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
• Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
• Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623 

Timestamps: 

0:00 - Intro: Tragedy and The Journey of Dr. Jen Ashton 2:05 - The Suicide of a Spouse: The Aftermath of Unimaginable Loss 4:26 - The Clinical Definition of Shock and Shattered Reality 5:10 - How Motherhood Becomes a Lifeline Through Trauma 6:32 - Writing the Book: The Obligation to Talk About Suicide 10:12 - Mental Health vs. Longevity: We Can’t Separate Mind and Body 11:40 - Social Media and the Real-Time Human Experiment on Mental Health 14:12 - The Anchor: How Fitness and Lifting Saved Dr. Ashton 16:29 - Post-Traumatic Growth: Her Children’s Incredible Wisdom 18:20 - Prioritizing Mental Health: The Checkup From the Neckup 19:18 - Suicide is a Disease: It's Not Something You Can "Think Your Way Out Of" 22:25 - Finding Love Again: The Miracle of Tom Werner 24:39 - Meeting Her Husband: A Harvard Grad and Titan in Sports/TV 28:13 - The Responsibility of a Public Figure to Be Transparent 30:04 - Transition to Correspondent: The Iron Man of Medical Communication 34:04 - Distilling Health Information: Why Credentials Matter 34:41 - The Economist Who Wrote a Pregnancy Book (Stay In Your Lane) 37:25 - The Humility of Science: We Must Be Prepared to Be Wrong 38:04 - The WHI Disaster: Flawed Data and Misrepresenting Menopause 40:08 - The Problem with Extremes: Why Moderation is Missing in Health 41:33 - The Narrative Risk: Why Telling Women They Are "Passive Victims" is Insulting 46:33 - Menopause Done Well: A Holistic Approach with Options 48:07 - Are Hormones Safe? Insights from a Practicing OB/GYN 51:08 - Non-Hormonal Options for Menopause Symptoms 53:27 - Favorite Hormone Delivery Method (Pill vs. Patch) 54:14 - GLP-1 Myths: Risk vs. Benefit and Thinking Like a Doctor 56:16 - Non-Weight Related Benefits of GLP-1s (Cognitive, Cardiac, Renal) 57:38 - Absolute vs. Relative Risk: The Math Behind Rare Side Effects 58:42 - Future of Obesity Management: Low-Dose GLP-1, HRT, and Anabolic Agents 1:00:15 - Maintenance Protocols: Why Physicians are DIYing Long-Term Care 1:00:54 - The Biggest GLP-1 Concern: Losing Too Much Muscle Mass 1:02:16 - The Hypothalamic Set Point: Why 90% of Diets Fail 1:06:39 - Society's Fat Shaming Bias: Obesity is a Chronic Disease 1:08:00 - Nutritional Gynecology: Connecting Food and Reproductive Stages 1:10:07 - Meeting the Four S’s: Safe, Simple, Sustainable, and Low Sugar 1:11:50 - Foundational Principles: Why Protein is Everything 1:14:35 - The Biggest Myth: Women Should Never Do Intermittent Fasting 1:16:26 - Hormesis and Adaptation: Applying Pressure to the System 1:17:33 - Resilience is a Practice: The Mental Framework for Internal Strength 1:20:57 - The Sisterhood of Women: Community is Crucial for Support 1:25:24 - Home Base: Tom Werner's Legacy of Helping Veterans

Disclaimers: This episode includes paid sponsorships. 

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

Dr. Gabrielle Lyon sits down with fertility specialist Dr. Natalie Crawford to tackle the urgent rise in infertility across both men and women. Dr. Crawford, an advocate for proactive reproductive health, reveals why inflammation is hijacking your fertility and why the old dogma that "age is the only factor" for egg quality is dangerously incomplete.

They cover critical, actionable steps—from the most important lifestyle changes you can make before IVF, to the toxic habits that are directly lowering sperm counts and causing miscarriages. Learn the three essential fertility awareness methods (FAMs) and what your doctor is missing when they check your thyroid.

Who is Natalie Crawford:

Natalie Crawford is a double board-certified fertility doctor with a nutrition background, here to help you understand your body and hormones, optimize your lifestyle, and take control of your reproductive future with confidence.

Thank you to our sponsors: 

• Timeline - Get 20% off your order at https://timeline.com/LYON    
• BON CHARGE Holiday Sale https://boncharge.com for 25% off 
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• 
  

Find Natalie Crawford at: 

• Web: https://www.nataliecrawfordmd.com/
• https://www.youtube.com/c/NatalieCrawfordMD/videos
• PODCAST
• https://www.nataliecrawfordmd.com/blog-1
• 
  

Find Dr. Gabrielle Lyon at: 

• Instagram:@drgabriellelyon 
• TikTok: @drgabriellelyon
• Facebook: facebook.com/doctorgabriellelyon
• YouTube: youtube.com/@DrGabrielleLyon
• X (Twitter): x.com/drgabriellelyon
• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
• Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
• Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623 

Disclaimers: This episode includes paid sponsorships. 

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Timestamps: 

0:00 - Inflammation is Hijacking Your Fertility 

2:00 - The Infertility Crisis: 1 in 5 Couples Struggle 

3:41 - Male vs. Female: Who is Becoming More Infertile? 

4:03 - Sperm Counts Down 50% & The Rise of Premature Menopause 

4:57 - The #1 Cause of Infertility: Chronic Inflammation 

6:08 - Egg Quality: You CAN Influence Your Mitochondrial Health 

8:18 - The 5 Pillars of Fertility: Sleep, Stress, Muscle, Diet, Toxins 

8:53 - The Foundation: Why Sleep is Non-Negotiable for Hormones 

11:13 - Fertility is a Team Sport: Why Sleep Impacts Men More Quickly 

12:55 - How Much Sleep Do You Need? (Circadian Rhythm is Crucial) 

15:19 - Supplements and Herbs: The Danger of Chaste Tree Berry (Vitex) 

18:38 - The Problem with Glandular & Adrenal Support Supplements 

22:31 - Alcohol and Cannabis: Why They are Profoundly Inflammatory 

24:49 - Miscarriage Risk: Male Cannabis Use & Uterine Septum 

25:57 - Autoimmune Disease: Celiac, Thyroid, and Miscarriage 

28:03 - Celiac Disease: Treating the Root Cause of Inflammation 

29:32 - The Fellow's Journey: Why Dr. Crawford Studied Natural Fertility 

33:24 - The 12-Month Prep Plan: Screening for Autoimmunity (Thyroid/Celiac) 

34:07 - Hashimoto's & Thyroid: Why Your TSH Range is Misleading 

37:34 - Period Problems: When a "Regular" Cycle Isn't Ovulating Optimally 

40:27 - Thyroid Treatment: Synthetic vs. Animal-Derived Hormones 

44:09 - Environmental Toxins: Their Huge Role in Fertility & Ovarian Reserve 

46:09 - Where to Start: Water, Air Filters, and Non-Teflon Cookware 

48:54 - Toxins: Stainless Steel, Glass, and Avoiding Hot Plastic 

50:45 - Processed Foods and Takeout: The Danger of Packaging 

54:24 - Sex for Conception: How Much is Enough? (No Need to Abstain) 

56:41 - Use It or Lose It: Why the Vagina Can Atrophy 

57:56 - The 3 Fertility Awareness Methods (FAMs) to Track Ovulation 

1:00:59 - Basil Body Temperature & Wearable Tech for Ovulation

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Dr. Gabrielle Lyon reveals the biggest mistakes Americans make with their nutrition and body composition, especially after age 40. With 75% of Americans overweight or obese, the problem is clear: excess calories from cheap, processed carbohydrates.

Dr. Lyon dissects the metabolic science, explaining why skeletal muscle—the largest organ—is not designed to dispose of the massive carb loads found in the average American diet. Learn the essential strategies, including the 1:1 Protein-to-Carbohydrate Ratio Rule and the importance of Carbohydrate Tolerance, to design a meal plan that maximizes muscle, controls insulin, and guarantees success.

Nick Barringer is an expert on nutrition and performance for the tactical athlete. Nick Barringer currently serves as the Program Director for the Army-Baylor University Master’s Program in Nutrition. Barringer has a Doctorate degree in Kinesiology from Texas A&M University and received his undergraduate degree in dietetics from the University of Georgia. Barringer previously served as an assistant professor at the United States Military Academy at West Point and as the Regimental Nutritionist and as a member of the Ranger Athlete Warrior (RAW) program at the 75th Ranger Regiment. Nick has gone through physically demanding courses such as Ranger School, Survival Evasion Resistance Escape(SERE), Airborne, Air Assault as well as having deployed to both Iraq and Afghanistan.

Thank you to our sponsors: 

BodyHealth - Use the code LYON 20 to get 20% off your first order bodyhealth.com

PIQUE - Get 20% off for life + a complimentary gift Piquelife.com/DRLYON

Timeline - Get 20% off your order at https://timeline.com/LYON   

OneSkin - Get 15% off with the code DRLYON – https://www.oneskin.co

Find Nick at: 

•  https://www.instagram.com/nickbarringer.phd.rdn
• https://drnickbarringer.com/

Find Dr. Gabrielle Lyon at: 

• Instagram:@drgabriellelyon 
• TikTok: @drgabriellelyon
• Facebook: facebook.com/doctorgabriellelyon
• YouTube: youtube.com/@DrGabrielleLyon
• X (Twitter): x.com/drgabriellelyon
• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
• Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
• Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623 

Disclaimers: This episode includes paid sponsorships. 

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

Want ad-free episodes and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

Become a patient: https://strongmedical.com/apply-now/?utm_source=youtube&utm_medium=video&utm_campaign=strongmedical&utm_content=description

In this empowering episode, Dr. Gabrielle Lyon sits down with the incredible mother-daughter duo, Michelle and Joan MacDonald, to share the blueprint for radical physical transformation at any age. Joan, who began her journey nearing 71 years old, proves it's never too late, while coach Michelle, a Certified Strength and Conditioning Specialist (CSCS), cuts through the noise on training, nutrition, and mindset.

They tackle deeply personal topics, including Michelle's 15-year struggle with a severe eating disorder and the shame that surrounds women's health. This is a must-watch to learn the non-negotiable pillars for building a strong, resilient, and healthy body, no matter your starting point.

Michelle MacDonald is a trailblazer in the global movement to redefine aging and female

empowerment through strength. As the founder of The Wonderwomen, a world-class coaching

brand built on her signature methodology, The Fitness Model Blueprint™, Michelle has

transformed thousands of women—inside and out—with evidence-based strategies that merge

mindset, muscle, and metabolic mastery.

Joan MacDonald (Fitness Icon and Mother)

At 70, Joan MacDonald was getting winded walking up a flight of stairs and now, at 74, she is doing weighted pull-ups and 200 lb hip thrusts.

This episode is sponsored by:

- Branch Basics - 15% off and free shipping on the Starter Kit when you use code DRLYON at BranchBasics.com/DRLYON

- BON CHARGE Holiday Sale https://boncharge.com for 25% off

- Manukora - BLACK FRIDAY SALE: Save $151 on Manukora Starter Kit MANUKORA.com/DRLYON

Chapters:

0:00 - The ED Crisis: Michelle’s 15-Year Battle & Recovery

2:04 - Joan Started Lifting at 71: Debunking the Age Myth

6:16 - Pillars of Transformation: Mindset, Sleep, Food

8:52 - Finding Your "Why": Aesthetics vs. Longevity

12:01 - Why Strength Training Must Come First

14:28 - Grittiness: The Secret to Joan's Radical Success

24:54 - Hard Truths: The "Nursing Home" Speech That Changed Joan's Life

26:47 - The Transformation Container: Non-Negotiables for Success

47:03 - Disordered Eating: When to Get Expert Therapy vs. Coaching

50:11 - GLP-1s and the "Food Noise" Solution

58:12 - 3 Essential Beginner Exercises (Joan's Choices)

1:04:22 - Strength Goals: The 3 Exercises a Strong 40-Year-Old Must Master

1:10:29 - The Hip Thrust: #1 Glute Builder and Muscle Mandate

1:14:09 - Training is a Skill: How to Prevent Injury

1:19:11 - Core Strength: Why Glutes and Abs Prevent Falls

1:33:37 - Training the Individual: Why Age Doesn't Matter

1:37:29 - Nutrition Blueprint: Protein First for Satiety and Adherence

Find Michelle at:

https://www.instagram.com/yourhealthyhedonista/

http://MichelleMacdonaldOfficial.com

Podcast: https://podcasts.apple.com/us/podcast/the-wonder-women-official/id1677831398

Find Joan at:

https://www.instagram.com/trainwithjoan

https://www.trainwithjoanofficial.com

Find Dr. Gabrielle Lyon at:

- Instagram:@drgabriellelyon

- TikTok: @drgabriellelyon

- Facebook: facebook.com/doctorgabriellelyon

- YouTube: youtube.com/@DrGabrielleLyon

- X (Twitter): x.com/drgabriellelyon

- Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/

- Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page

- Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

This episode includes paid sponsorships.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

In this compilation episode, Dr. Gabrielle Lyon is joined by the top experts in Testosterone and men's health treatments.

You'll learn:

• Why aging alone doesn't drop T levels and why acquisition of conditions like obesity is the real culprit.
• Why the standard "low T" cutoff is misleading and why you must check your Free Testosterone.
• How erectile dysfunction is a sensitive marker of overall health and heart risk.
• The efficacy of Cialis/Viagra for both erections and cardiac protection, and the risks of unchecked influencer advice on steroids.
• The direct link between muscle mass, exercise, and sexual function—and why the penis is the "first to go" when overall health declines.

Chapter Markers:

0:00 - Testosterone is a Brain Hormone

0:40 - Debunking the Myth: Male Menopause (Andropause) Doesn't Exist

1:33 - The Dangers of Unchecked Influencer Advice on Testosterone

3:07 - Defining Testosterone Deficiency: Symptoms vs. Signs

5:10 - The Arbitrary Number: Why Guidelines Disagree on Low T

8:29 - Free Testosterone: The Most Reliable Indicator of Male Health

15:28 - TRT vs. Steroids: Defining the Line and Risks

18:59 - The Real Risks of TRT: Infertility and Hematocrit

22:36 - The Shocking Backstory: Challenging the Prostate Cancer Myth

26:40 - Erectile Dysfunction (ED) and Lifestyle Modification

29:21 - Shockwave Therapy for ED: The Science and the Cash Business

33:53 - Penile Tissue Atrophy and Venous Leak

37:25 - The Role of Muscle Mass, Sarcopenia, and Sexual Function

39:41 - The Single Best Marker for Male Health: Erectile Function

42:02 - The Science of Cialis and Viagra (PDE5 Inhibitors)

45:49 - The Viagra Story: From Heart Drug to ED Cure

50:50 - Tadalafil (Cialis) as a Triple-Threat Drug (Cardiac, Urinary, Sexual)

53:57 - The Role of Testosterone in Female Sexual Function

55:20 - Hypogonadism: Diagnosis, Treatment, and Fertility Risk

About the guests:

Dr. Abraham Morgentaler is an Associate Clinical Professor of Urology at Harvard Medical School and founder of Men's Health Boston. He is an internationally recognized expert in men's health, particularly known for his pioneering work in testosterone therapy. Dr. Morgentaler is credited with reversing the long-held belief that testosterone therapy causes prostate cancer and is the author of several books on men's health.

• YouTube
• LinkedIn
• T4L Education
• X/Twitter 

Dr. Tobias Kohler is the co-founder of the Erectile Restoration Outcomes Study (EROS) penile implant registry. In addition to his clinical and research activities, Dr. Kohler is active in education, providing mentorship to residents and fellows.

• Mayo Clinic
• ResearchGate
• LinkedIn
• X(Twitter)

Dr. Mohit Khera, M.D., M.B.A., M.P.H., is a urologist and professor at Baylor College of Medicine. He is an expert in male and female sexual dysfunction and testosterone replacement therapy, and his work focuses on male infertility, sexual dysfunction, and declining testosterone levels. He is also the President of the Sexual Medicine Society of North America.

• Twitter 
• Instagram
• Website
• Media Appearances

Thank you to our sponsors:

• Hollow Socks - Buy 3, Get 3 Free at https://hollowsocks.com
• Cozy Earth - https://cozyearth.com/DRLYON for up to 40% off
• Timeline - Get 20% off your order at https://timeline.com/LYON
• Our Place - Save up to 35% sitewide through December 2nd at https://fromourplace.com

Disclaimers:

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

This episode includes paid sponsorships.

Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/

Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com

In this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of social connection, emotion, and cognitive health. Dr. Rein, an expert in neurobiology and psychedelic research, reveals the cutting-edge studies that explain why loneliness is as damaging as smoking and how our digital world is affecting our brain's ability to connect.

They discuss the neurochemistry of love, the controversial use of MDMA in therapy, and whether AI can ever truly replace human intimacy. This conversation provides an essential look at the biological drivers of happiness, performance, and long-term brain health.

Chapter Markers:

0:00 - MDMA (Molly): The History & Therapeutic Benefits

5:59 - The Legal Status of MDMA for PTSD

6:44 - The Safety and Effectiveness of MDMA in Clinical Trials

8:29 - PTSD (The Amygdala Alarm)

9:41 - How MDMA Soothes the Amygdala to Access Memory

11:42 - Is There an Alternative to MDMA? (Ketamine's Mechanism)

13:16 - Ketamine and Neuroplasticity for Depression

15:48 - Botox and Empathy:

18:12 - The Problem of Volume: How Screens Depersonalize Interaction

19:48 - The Virtual Disengagement Hypothesis Explained

25:00 - Defining Cognitive and Emotional Empathy

29:43 - MDMA's Link to Serotonin & Social Reward

31:04 - Do SSRIs Have Pro-Social Effects?

36:10 - The Science of Likability and "Easy to Read" Faces

40:10 - Top 3 Ways to Be More Likable

49:49 - The Likability Gap: Why You Underestimate How Well-Liked You Are

56:59 - The Neurobiology of Oxytocin, Dopamine, and Serotonin

1:09:23 - The Goldilocks Zone of Empathy

1:15:58 - Narcolepsy

1:18:16 - Alcohol: Why the Neurotoxin is Bad for Brain Health

1:21:47 - Exercise and Neurogenesis

1:22:27 - Sex, Orgasm, and Oxytocin Release

1:25:06 - Oxytocin During Childbirth

Who is Ben Rein:

Dr. Ben Rein is an award-winning neuroscientist and Chief Science Officer of the Mind Science Foundation, where he supports early-career researchers in neuroscience. He earned his PhD from SUNY Buffalo and completed postdoctoral training at Stanford University, publishing over 20 peer-reviewed papers on autism, empathy, MDMA, and digital behavior. Recognized by the NIH, the Society for Neuroscience, and Sigma Xi, he also serves as a scientific advisor to more than 20 organizations. With over one million followers and 75 million video views, Dr. Rein is celebrated for making neuroscience accessible to the public and has been featured by outlets such as Good Morning America, ABC News, and PopularMechanics.

Thank you to our sponsors:

BodyHealth: Use code LYON20 to get 20% off your first order https://www.bodyhealthaffiliates.com/73L4QL3/7XDN2/

BON CHARGE Holiday Sale https://boncharge.com for 25% off

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Find Ben Rein at:

• Website: https://www.benrein.com/
• Instagram: https://www.instagram.com/dr.benrein/#
• TikTok: https://www.tiktok.com/@dr.benrein?lang=en
• Facebook: https://www.facebook.com/benreinneuroscience/
• Youtube:  @dr.benrein 

Find Dr. Gabrielle Lyon at:

• Instagram:@drgabriellelyon
• TikTok: @drgabriellelyon
• Facebook: facebook.com/doctorgabriellelyon
• YouTube: youtube.com/@DrGabrielleLyon
• X (Twitter): x.com/drgabriellelyon
• Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/
• Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page
• Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

Disclaimers:

This episode includes paid sponsorships.

The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.