• 1 hour 8 minutes
    Dr. Tiffany Moon: Is Anesthesia Safe? What Patients Fear vs. What Actually Happens

    In this episode, board-certified anesthesiologist, researcher, and former Real Housewives of Dallas star Dr. Tiffany Moon pulls back the curtain on modern medicine, surgical pain management, and the reality of navigating elite academia. From addressing widespread public fears around clinical fentanyl use to detailing why she was branded an "embarrassment" by academic peers for appearing on reality television, Dr. Moon speaks candidly about breaking stereotypes, the gender pay gap in healthcare, and using a massive public platform to advocate for science and mentorship.

    What You'll Learn In This Episode:

    • The Clinical Truth About Fentanyl: Why it is the standard of care for 90% of surgeries, and why post-op patients shouldn't fear becoming addicted.
    • The Reality TV Fallout: How appearing on The Real Housewives led to institutional blowback—and why she’d do it again.
    • Leveraging Fame for Science: Turning pop culture visibility into serious advocacy for mentorship, healthcare equity, and closing the gender pay gap.
    • Shattering Stereotypes: Moving past appearances to run clinical trials, publish randomized controlled studies, and teach the next generation of physicians.

    Thank you to our sponsors:

    • Cozy Earth: cozyearth.com Use code DRLYON for 20% off
    • Our Place: fromourplace.com Use code DRLYON for 10% off
    • Branch Basics: branchbasics.com Use code DRLYON for 15% off Premium Starter Kit

    Explore More from Dr. Gabrielle Lyon

    • Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/
    • Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patient

    Find Dr. Tiffany Moon at:

    • Instagram: instagram.com/tiffanymoonmd (@tiffanymoonmd)
    • TikTok: tiktok.com/@tiffanymoonmd (@tiffanymoonmd)
    • YouTube: youtube.com/@TiffanyMoonMDOfficial (@TiffanyMoonMDOfficial)
    • Website: tiffanymoonmd.com
    • Facebook: facebook.com/tiffanymoonmd (@tiffanymoonmd)
    • X (Twitter): x.com/TiffanyMoonMD (@TiffanyMoonMD)

    Connect with Dr. Gabrielle Lyon:

    • Instagram: / drgabriellelyon
    • TikTok: / drgabriellelyon
    • X (Twitter): https://x.com/drgabriellelyon
    • Facebook: / doctorgabriellelyon

    Chapters

    00:00 – The Truth About Fentanyl in Surgery

    01:18 – Breaking Stereotypes in Academic Medicine

    12:00 – Pain Protocols, Anesthesia Safety & Clinical Trials

    25:00 – Reality TV, Academic Backlash & Healthcare Equity

    40:00 – Career Reinvention & Overcoming Physician Burnout

    1:00:00 – Why Preventive Medicine Is the Future

    1:08:39 – Longevity Medicine, GLP-1s & Muscle Health

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    13 October 2026, 1:00 pm
  • 17 minutes 55 seconds
    Hormones and Attraction: What We Think We Know vs. What the Science Says

    Can you tell someone's testosterone or estrogen levels just by looking at their face? Is "jawmaxxing" actually backed by science? In this video, we dive deep into the real science of hormones, physical attraction, and evolutionary biology.

    We debunk popular myths around high testosterone, facial masculinity, and ovulation preferences, revealing what the research actually shows about human mate selection. Discover why facial structure isn't a hormone panel, how estrogen impacts skin and collagen as women age, and why physical strength accounts for 70% of perceived bodily attractiveness.

    If you want to understand how hormones shape our development—and why muscle is the single most modifiable signal of health and longevity—this episode is for you.

    Find Dr. Gabrielle Lyon at:

    - Instagram: https://www.instagram.com/drgabriellelyon/

    - TikTok: tiktok.com/@drgabriellelyon

    - Facebook: facebook.com/doctorgabriellelyon

    - YouTube: youtube.com/@DrGabrielleLyon

    - X: x.com/drgabriellelyon

    - Apply to become a patient: https://drgabriellelyon.com/new-patient-inquiry/

    - Weekly newsletter: https://institute-for-muscle-centric-medicine.ck.page

    - Order my new book: https://www.amazon.com/exec/obidos/ASIN/1668085623

    Chapters:

    00:00 What role do hormones play in the traits we find attractive?

    00:46 High vs. low testosterone: does it change who we pick?

    01:44 The ovulation story: do women seek out masculine men?

    03:19 Two questions: can you see hormones, and what's modifiable?

    04:12 What testosterone and estrogen build during development

    05:23 Does winning raise testosterone? What a masculine face tells you

    06:26 Selection, training and genes: why muscle isn't just testosterone

    07:54 Are women attracted to testosterone? What the longitudinal studies show

    09:29 Face vs. strength: what predicts mating success

    10:08 The 70% finding: strength and bodily attractiveness

    11:44 Why strength is a hard-to-fake health signal

    13:41 Can you see estrogen? Facial ratings and why more isn't better

    14:41 Culture moves beauty standards, and estrogen shows up in skin

    16:08 Estrogen therapy and skin: what it can and can't do

    16:36 Can you see hormones? Muscle is the system you can see and change

    Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    8 October 2026, 1:00 pm
  • 1 hour 30 minutes
    Dr. JJ Thomas: Pain Is an Alarm. Why Your Injury Keeps Coming Back and How To Fix It

    When you have musculoskeletal pain, the natural instinct is to try and treat it directly. But the cause of that pain often starts somewhere else in the body.

    I learned that from this week's guest, Dr. JJ Thomas, who is my physical therapist and good friend. She was my patient first, and now we are each other's patients. She has practiced physical therapy for more than 25 years and has worked with the Philadelphia 76ers, the Philadelphia Eagles, and athletes from the UFC and US Olympic programs.

    What you'll learn in this episode:

    • Why a chronic tendon injury can come right back, even after eccentric loading or PRP
    • Whether a frozen shoulder in menopause is a hormone problem, and one of the first movements Dr. Thomas checks
    • Why she works lying on her stomach, and the 10-minute band routine she wrote for an eight-hour desk day
    • Why sitting up taller won't fix your posture, and what poor posture tells her about your body
    • Why she gives patients shoulder blade exercises for their pelvic floor
    • How much a standard squat does for your posterior chain, and the position she wants you in more often
    • Why she believes “overuse” injuries are often underuse injuries, and how that changes the way she treats shin splints
    • Why needling a clinician's quad and adductors normalized his neck rotation
    • What her blood work showed after years of hard training, and the nutrition change she calls her “game changer”

    Thank you to our sponsors:

    • Manukora - Get 31% off at https://www.manukora.com/drlyon

    • Timeline - up to 20% off when you subscribe and save at https://www.timeline.com/lyon

    • Bon Charge - Use code DRLYON for 15% off at https://www.boncharge.com

    Explore More from Dr. Gabrielle Lyon

    Weekly newsletter: Recipes, podcast updates, and practical weekly insights https://drgabriellelyon.com/sign-up/

    Apply to become a patient: Personalized care with Dr. Lyon’s clinical team https://drgabriellelyon.com/new-patie...

    Find Dr. JJ Thomas at:

    • YouTube: https://www.youtube.com/@drjjthomas

    • Website: https://primalphysicaltherapy.com/

    • Instagram: https://www.instagram.com/drjjphysicaltherapist/

    Connect with Dr. Gabrielle Lyon:

    • Instagram: https://www.instagram.com/drgabriellelyon/

    • TikTok: https://www.tiktok.com/@drgabriellelyon

    • Facebook: http://facebook.com/doctorgabriellelyon

    • X: http://x.com/drgabriellelyon

    • Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/

    • Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page

    Chapters

    00:00 – Posture Myths & Why Sitting Up Straight Fails

    02:18 – Treating Root Causes vs. Bandaging Pain

    06:48 – The Hazards of Sitting & Reframing Movement as Health

    13:39 – The 7 Primal Movement Patterns Every Body Needs

    25:28 – Scapular Stability, Pelvic Health, and Primal Movements

    39:12 – Fixing Glute Amnesia & Activating the Posterior Chain

    51:57 – Why "Overuse" Injuries Are Really Underuse Problems

    58:34 – Dry Needling & System-Based Movement Resets

    1:13:53 – Dialing in Hormones, Protein, and Metabolic Health

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    6 October 2026, 1:00 pm
  • 17 minutes
    Is It Too Late to Build Muscle in Menopause? No. Here's What the Studies Show

    Will I get too bulky?" No. "Is it too late?" Also no. Here's the context: during the menopause transition, women lose lean mass, gain fat, and their muscle becomes harder to build — the same workout and the same protein meal produce less than they did at 30. For years the only conversation has been hormone therapy, yes or no, as if that were the fix. In Part 2 of her menopause series, Dr. Gabrielle Lyon looks at what the evidence actually says builds muscle back.

    In this episode:

    -Postmenopausal women can build muscle and strength at any age (Frontiers in Endocrinology)

    - Up to 8 lbs of skeletal muscle in 12 weeks (J Nutr Health Aging RCT)

    - Anabolic resistance: why the same workout and the same meal produce less after menopause

    - "I was wrong": hormone therapy vs. lifting, and the conversations with Dr. Donald Layman

    - HRT alone and lean mass: a 0.06 kg difference across 12 trials

    - Estradiol plus training: bigger quad and fat-free mass gains, maintained at 12 months

    - Lift first — the practical translation while the HRT evidence evolves

    - Why protein matters more after menopause, and why 60 g spread thin isn't enough

    - The RDA (0.8 g/kg) isn't enough to protect bone; ESCEO's 1–1.2 g/kg floor

    - Doubling protein to 1.6 g/kg: more fat lost, more lean mass kept

    - The 6-step Forever Strong menopause protocol

    Sponsor

    David Protein — 28 g of protein, 150 calories, zero sugar → davidprotein.com/drlyon, subscribe to save 10% on every order

    Find Dr. Gabrielle Lyon at:

    - Instagram: https://www.instagram.com/drgabriellelyon/

    - TikTok: tiktok.com/@drgabriellelyon

    - Facebook: facebook.com/doctorgabriellelyon

    - X: x.com/drgabriellelyon

    - Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/

    - Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page

    Chapters:

    00:00 Will I get too bulky? Is it too late? Both answers are no

    01:09 Postmenopausal women gained up to 8 lbs of muscle in 12 weeks

    02:24 Anabolic resistance: more volume, more intensity, more protein

    03:34 Hormone therapy or lifting? "I was wrong"

    05:16 HRT alone and lean mass: 0.06 kg across 12 trials

    06:16 Estradiol amplifies training — it doesn't replace it

    07:22 Lift first: what to do while the evidence evolves

    10:21 Why protein matters more after menopause (and why 60 g isn't enough)

    11:16 The RDA won't protect your bones: the 1–1.2 g/kg floor

    12:16 Doubling protein: more fat lost, more lean mass kept

    13:22 The Forever Strong protocol, step 1: train 2–3 days a week

    14:15 Steps 2–3: 30–50 g protein at first and last meal, impact and loading

    15:13 Steps 4–6: hormone therapy with training, body composition, blood work

    16:07 You're not alone: the Menopause Challenge

    Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.

    1 October 2026, 1:00 pm
  • 1 hour 17 minutes
    How to Prepare Your Body for Surgery: Protein, Prehab and the 5 Days That Change Your Recovery | Dr. Rebecca Knackstedt

    Most patients are told one thing before surgery: stop all supplements. Duke surgeon Dr. Rebecca Knackstedt says that blanket advice can do harm, and that what you do in the days before surgery changes how you heal.

    Dr. Knackstedt is a plastic and reconstructive microsurgeon on faculty at Duke, an MD-PhD researcher and a certified functional medicine provider whose research focuses on surgical prehabilitation: preparing the body, mind, and home before surgery, the way we already do with rehab.

    In today’s episode, we discuss:

    • What prehab looks like for any operation

    • The labs she checks

    • Which supplements to keep and which to stop (omega-3s do not increase bleeding)

    • Hormones after breast cancer

    • Why mammograms still beat thermography

    • What chemo does to metabolism

    • The questions to ask your oncologist before a treatment decision

    • How much protein to eat (no standard exists, and the average woman gets 60 to 70 grams a day, well short of the 100-gram floor)

    • Why surgery is catabolic and muscle is your reserve

    • Carbohydrate loading before the fasting cutoff and why it can reduce pain

    • The five-day window that lowered complications and even mortality in head and neck cancer patients

    • Why early walking replaced routine bed rest

    Connect with Dr. Knackstedt

    Instagram → https://www.instagram.com/surgical_recovery/

    Website → https://www.clararecovery.com/

    Sponsors

    • Perfect Amino by BodyHealth, https://bit.ly/4wZgg6N, code LYON20 for 20% off your first order

    • Timeline Mitopure → https://bit.ly/4x18cm5, for an extra 20% off

    • Lola Blankets → lolablankets.com (http://lolablankets.com/), code: DRLYON for 40% off select blankets (limited time)

    Find Dr. Gabrielle Lyon at:

    • Instagram: https://www.instagram.com/drgabriellelyon/

    • TikTok: tiktok.com/@drgabriellelyon

    • Facebook: http://facebook.com/doctorgabriellelyon

    • X: http://x.com/drgabriellelyon

    • Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/

    • Weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page

    Chapters:

    00:00 Prehab saves lives and money. So why isn't it standard of care?

    01:05 Meet Dr. Rebecca Knackstedt: Duke microsurgeon and functional medicine provider

    05:35 The patient who changed everything, and why good surgery isn't enough

    08:34 What prehab is, and the exercises to do before any surgery

    12:14 Hormones after breast cancer, rising rates in young women, and real risk factors

    18:42 Chemo, metabolic syndrome and why body composition matters

    23:13 The end of bed rest, and the labs that matter before surgery

    27:04 Mammograms vs. thermography, and absolute vs. relative risk

    34:12 Protein before surgery: 2 g/kg, track 3 days, never under 100 g

    38:43 Supplements to take, and why "stop all supplements" is wrong

    44:40 Preparing the mind: anxiety, sleep, anesthesia depression, expectations

    51:21 Red light, saunas, hyperbaric oxygen, wound vacs, scars and pain control

    1:04:59 Surgery is catabolic: muscle as your glucose reserve

    1:07:34 Carb loading, the 5-day window, probiotics and the surgery go-bag

    1:14:15 Why prehab isn't standard of care yet, and why she's hopeful

    Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.

    29 September 2026, 1:00 pm
  • 22 minutes 6 seconds
    Menopause Is a Muscle Problem, Not Just a Hormone Problem

    Menopause is changing your body, but the part nobody talks about isn't hot flashes. It's muscle. Women lose lean mass fastest in perimenopause, the loss probably starts closer to 35, and no pill, patch or injection fixes it.

    In this solocast, Dr. Gabrielle Lyon explains what estrogen, testosterone and FSH actually do to your metabolism, why a 50-year-old body can still build muscle, and the training and protein protocol to start now.

    Join the Menopause Challenge →

    https://drgabriellelyon.com/menopause-challenge/

    [Use Code 25OFF through Sept 27]

    Thank you to our sponsors:

    - Rula, therapy covered by insurance → rula.com/drlyon

    Find Dr. Gabrielle Lyon at:

    - Instagram: https://www.instagram.com/drgabriellelyon/

    - TikTok: @drgabriellelyon

    - Facebook: facebook.com/doctorgabriellelyon

    - YouTube: youtube.com/@DrGabrielleLyon

    - X (Twitter): x.com/drgabriellelyon

    - Apply to become a patient – https://drgabriellelyon.com/new-patient-inquiry/

    - Join my weekly newsletter – https://institute-for-muscle-centric-medicine.ck.page

    - Pre-order my new book - https://www.amazon.com/exec/obidos/ASIN/1668085623

    Chapters:

    00:00 Menopause is changing your body — but it doesn't have to change your life

    00:59 The suitcase story: today is about muscle, not hot flashes

    01:47 Hormone therapy, yes or no? Why that's the wrong first question

    03:36 What menopause is, when it arrives, and 40% of your life after it

    04:37 When lean mass really starts to fall — and why testing misses it

    06:46 Testosterone vs. estrogen: no two women go through it the same way

    08:40 Anabolic resistance: why the muscle-building switch gets sticky

    10:31 Estrogen, joints and injury risk (Dr. Jocelyn Wittstein)

    13:27 Less muscle, nowhere to put carbs: the lean prediabetic patient

    14:19 Falls, fractures, heart disease, and muscle as an early bone signal

    16:14 Visceral fat, energy expenditure, fat oxidation and FSH

    18:02 Test your blood — and pull the levers you control

    19:00 The starting protocol: 2–3 days a week and the movements to keep

    20:30 Menopause changes your body, not your life — the Menopause Challenge

    Mentioned

    - Dr. Jocelyn Wittstein on estrogen, joints and injury risk → https://youtu.be/ILyzNTjZTGI

    - Juliet & Dr. Kelly Starrett on floor sitting and mobility → https://youtu.be/QOjzh-711Q0

    - SWAN (Study of Women's Health Across the Nation)

    - The Lancet Diabetes & Endocrinology review on lean mass and chronic disease

    - ESCEO guidance on muscle and bone

    Disclaimers: This episode includes paid sponsorships. The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    24 September 2026, 1:00 pm
  • 1 hour 11 minutes
    ED Predicts Heart Attacks Better Than Chest Pain: The 2 Tests to Ask For | Dr. Tobias Kohler

    Your testosterone number matters at every age, but most men never learn what theirs should be. Mayo Clinic urologist Dr. Tobias Kohler explains why ~500 is the target, why 1,000 is already running hot, what 2,000+ does to the heart, and why a randomized trial found lifting without steroids beat steroids without lifting. Plus: the blood test that catches heart risk your cholesterol panel misses.

    Dr. Kohler returns for his second appearance (his first, on erections, testosterone and muscle mass, is one of the most-watched episodes in the show's history). This time: why men's longevity is roughly 50 years behind women's; the Princeton IV consensus he co-chaired, which treats ED as one of the strongest predictors of a future heart attack and points young men toward a coronary calcium scan; the 0–12 ceramide blood test that changes with your behavior; how to get a testosterone baseline that actually means something; what redlining to 2,000–3,000 does to the heart, the set point and the skin; Peyronie's disease, Viagra vs. Cialis, the pills-to-implant ladder, sexual rehab after prostate surgery, and a patient who got stronger with zero testosterone.

    About Dr. Tobias Kohler

    Tobias S. Kohler, MD, MPH, is Professor of Urology at Mayo Clinic, a fellowship-trained andrologist with 25+ years of clinical and surgical experience and 250+ peer-reviewed publications. He co-chaired the Princeton IV Consensus Guidelines on ED and cardiovascular disease, co-founded the EROS penile implant registry, and co-edited Contemporary Treatment of Erectile Dysfunction (2nd ed.).

    🙌 Thank you to our sponsors:

    Cozy Earth - Get 20% off at https://bit.ly/3RLZNEv

    Egg Life - https://bit.ly/4yxBs5l

    Ladder - https://bit.ly/4ggxfLK

    📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

    YouTube: https://bit.ly/4boCFC3

    Spotify: https://bit.ly/4cWTbLG

    📱 Connect with Dr. Gabrielle Lyon:

    Instagram: https://bit.ly/4uk9adc

    TikTok: https://bit.ly/3OFK3kJ

    X.com: https://bit.ly/4l3YlaX

    Facebook: https://bit.ly/3MBrJso

    LinkedIn: https://bit.ly/3N1nrdL

    Website: https://bit.ly/3NdV2kT

    Books: https://bit.ly/4r6ugZK

    Newsletter: https://bit.ly/402QCAj

    ⏰Chapters

    00:00 Men are dying earlier than women the penis is the check-engine light

    03:26 Boys stop seeing doctors for 20 years the case for an Office of Men's Health

    10:57 Princeton IV: ED predicts heart attacks, calcium scans, and Cialis

    12:44 The ceramide blood test your cholesterol panel can't replace

    20:37 Cardiac risk calculators, statins, and what your LDL should be

    25:38 GLP-1s, fertility, and "what's the risk of doing nothing?"

    29:05 Testosterone: the ~500 target, why 1,000 runs hot, what 2,000+ does to the heart

    31:44 Check your testosterone at 25 and why steroids won't make you a pro

    36:57 Tolerance and the new set point redlined men can't escape

    38:13 The 1980s trial: lifting without steroids beat steroids without lifting

    42:06 Steroid cocktails, arrhythmias, irreversible side effects, and the sarcopenia trade-off

    53:04 Peyronie's disease and Viagra vs. Cialis

    57:32 Penile implants: the knee-replacement analogy and the pills-to-surgery ladder

    1:02:27 Sexual rehab after prostatectomy and the questions to ask before cancer treatment

    1:07:55 Closing: be proactive and the patient who got stronger with zero testosterone

    Disclaimer: This podcast is for general informational purposes only and does not constitute medical advice or create a doctor–patient relationship. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not disregard or delay seeking medical advice because of something you heard here.

    22 September 2026, 1:00 pm
  • 25 minutes 13 seconds
    The Truth About Testosterone in Women

    You say "steroids" and picture a baseball scandal, a jacked guy, a bad spray tan. But cortisol is a steroid. Estrogen is a steroid. The cream you put on poison ivy is a steroid. The word covering all of them is also covering testosterone therapy for women, and that collision is quietly costing women muscle and bone they don't have to lose.

    In this solo episode, prompted by a magazine interview on steroid use in women, Dr. Gabrielle Lyon breaks down what these molecules actually are, what they do inside a cell, and why the line between medicine and misuse has nothing to do with the word "steroid."

    Study and References:

    The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in Normal Men (Bhasin et al., NEJM 1996) - https://pubmed.ncbi.nlm.nih.gov/8637535/

    Testosterone Enhances Estradiol's Effects on Postmenopausal Bone Density and Sexuality (Davis et al., 1995) - https://pubmed.ncbi.nlm.nih.gov/7616872/

    Global Consensus Position Statement on the Use of Testosterone Therapy for Women (2019) - https://pubmed.ncbi.nlm.nih.gov/31498...

    ISSWSH Clinical Practice Guideline for the Use of Systemic Testosterone for HSDD in Women (2021) - https://pubmed.ncbi.nlm.nih.gov/33814...

    The Global Epidemiology of Anabolic-Androgenic Steroid Use: A Meta-Analysis (Sagoe et al., 2014) - https://pubmed.ncbi.nlm.nih.gov/24582...

    What Is the Prevalence of Anabolic-Androgenic Steroid Use Among Women? A Systematic Review (Piatkowski et al., Addiction, 2024) - https://onlinelibrary.wiley.com/doi/1... "

    The Compounds for Females Are Really Commonly Faked!": Women's Challenges in Anabolic Steroid Acquisition (Piatkowski et al., Drug and Alcohol Review, 2024) - https://onlinelibrary.wiley.com/doi/1...

    Explore More from Dr. Gabrielle Lyon:


    📱 Connect with Dr. Gabrielle Lyon:

    Instagram: https://bit.ly/4uk9adc

    TikTok: https://bit.ly/3OFK3kJ

    X.com: https://bit.ly/4l3YlaX

    Facebook: https://bit.ly/3MBrJso

    LinkedIn: https://bit.ly/3N1nrdL

    Website: https://bit.ly/3NdV2kT

    Books: https://bit.ly/4r6ugZK

    Newsletter: https://bit.ly/402QCAj

    📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

    YouTube: https://bit.ly/4boCFC3

    Spotify: https://bit.ly/4cWTbLG

    ⏰ Chapters:

    00:00 - Beginning

    01:25 - Introduction: The Sister Who Says "Oh My Gosh, You're Taking Steroids" Why Medicine Needs a Shared Vocabulary

    03:43 - What a Steroid Actually Is: Four Rings of Carbon

    04:49 - Anabolic vs. Androgenic: Same Receptor, Different Effects

    06:16 - A Brief History: From Wasting Disease to the Weight Room

    08:59 - Restoring vs. Exceeding: Why the Range Is the Whole Game

    11:38 - The Davis Trial: Testosterone, Bone Density, and Lean Mass

    13:38 - Oral Compounds, the Liver, and Why Conversion Matters

    14:20 - What Gets Sold Isn't What's Labeled: The Australian Drug-Checking Data

    15:31 - The 1.6% vs. 4% Myth: Reading the Prevalence Data Correctly

    18:33 - Why GLP-1s Are Pushing Women Toward Androgens

    20:26 - Permanent Effects: Voice Changes and What the Literature Shows

    21:33 - The Four Questions to Ask Before Any Androgen Conversation

    24:25 - Closing: Entering the Sarcopenia Era

    ‼️ Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    17 September 2026, 1:00 pm
  • 1 hour 46 minutes
    Fathers Lose Testosterone When They Raise Their Kids | Aldrich Chan, Psy.D.

    Most people assume becoming a parent is an emotional change, but a measurable part of it is hormonal, and it happens in fathers too. I sat down with Aldrich Chan, Psy.D., to talk about what changes in the brain, why the split we draw between mind and body does not hold up, and what decides whether stress reads as manageable or overwhelming when the hormones are identical either way.

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    📱Connect with Aldrich Chan, Psy.D

    Website: https://www.drchancnc.com/

    YouTube: www.youtube.com/@draldrichan

    Instagram: https://www.instagram.com/draldrichan

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    LinkedIn: https://www.linkedin.com/in/draldrichan/

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    ⏰Timestamps:

    00:00 - Introduction: what a neuropsychologist measures

    03:25 - Mild cognitive impairment and proactive interference

    04:52 - The SAD theory: separation, alienation, discord

    06:30 - The default mode network and 46.9% mind wandering

    08:56 - Reframing ADHD as an evolutionary advantage

    18:21 - Evolutionary mismatch and hunter-gatherer comparisons

    21:03 - Neuroplasticity, epigenetics, and the 24-hour timeline

    24:29 - Mind-body dualism and the gut-brain connection

    31:31 - What fatherhood does to the brain and testosterone

    36:47 - Choice overload and the four-bit working memory limit

    39:54 - Temporal discounting and building immediate feedback

    43:23 - Vital signals and how to identify a core value

    49:49 - Intuition, somatic markers, and the vmPFC

    55:00 - The 20-watt brain versus a 10-gigawatt supercomputer

    01:02:58 - Only 35% of the brain is built at birth

    01:06:13 - Creativity, nothingness, and the fear of uncertainty

    01:16:31 - Process, flow states, and the jazz pianist studies

    01:22:53 - Mirror neurons, group selection, and the rat experiments

    01:34:20 - Eustress and the line between moderate and major stress

    01:44:39 - Alloparenting and what the Hadza numbers show

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

    15 September 2026, 1:00 pm
  • 24 minutes 36 seconds
    The Bone You Have At 50 Was Built Before You Turned 18

    You might think bone density is something you build slowly over a lifetime, but nearly all of your peak bone mass is set before age 18, in a four-year window most parents never see coming. In this solo episode I break down what happens to a child's skeleton during that window, what GLP-1 medications do inside a body that's still growing, and the protocol I'd want every parent to follow. Muscle and bone are not what a body has they're what a body was built to become.

    In this solo episode, Dr. Gabrielle Lyon breaks down the science of bone health in children, adolescent GLP-1 use, and muscle building in kids:

    • Why the four years around age 12 in girls and 14 in boys account for close to 40% of the total bone mineral a person will carry for life
    • Why a hip fracture in a healthy 29-year-old is almost always a story about a childhood building phase that never happened, often tied to a history of restriction like anorexia
    • What semaglutide and other GLP-1 medications do inside a still growing skeleton, and why no long term bone density data exists for adolescents on these drugs
    • Why a JAMA Network Open trial found the group combining liraglutide with resistance training lost the most weight with bone mineral density statistically unchanged, while the drug alone caused bone loss
    • The complete protocol for parents: track strength and function over the scale, muscle strengthening and bone loading exercise three days a week each, protein at breakfast, and a screen time floor instead of a ceiling

    Muscle and bone are not what a body has; they are what a body was built to become, and childhood is the only window that bone accrual and muscle development happen. Understanding pediatric bone health, sarcopenia in children, and the real research on GLP-1s and adolescents is the difference between guessing with your child's skeleton and protecting it on purpose.

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    Chapters

    00:00 - Introduction

    00:44 - The 29-Year-Old Who Fractured Her Hip

    01:20 - Muscle and Bone Are Childhood Assets

    03:01 - The Question I Keep Getting From Patients

    03:39 - The 30-Year Lifting Debate Is Over

    04:23 - Sarcopenic Obesity: More Muscle, Less Strength

    07:01 - What a Mouse Model Reveals About Muscle Potential

    08:24 - Screens: What the Data Shows

    10:00 - Food, Sleep, and the Screen-Weight Loop

    12:38 - GLP-1s in Teens: The STEP TEENS Trial

    13:52 - The Muscle Framing Mistake Everyone Makes

    16:49 - The Four-Year Window Bone Gets Built

    18:02 - The Trial That Proves Exercise Protects Bone

    20:29 - Prescribing Into an Unstudied Window

    20:46 - Why Lifting Doesn't Stunt Growth

    21:49 - Kids Get Stronger Without Building Muscle

    22:29 - The Protocol: What to Do Starting Today

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    10 September 2026, 1:00 pm
  • 1 hour 21 minutes
    The Testosterone Myth Women Have Been Lied To About │ Dr. Susan Hardwick-Smith

    You have probably been told that testosterone is a male hormone. Women produce more of it than estrogen, and for many of us it is the first hormone to go, sometimes reading zero five years before menopause while periods are still regular. Dr. Susan Hardwick-Smith and I get into what that costs you in muscle and bone, why there are thirty-one approved testosterone products for men and none for women, and what the number on your own lab report is measuring.

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    Create Her: Aging into the Healthiest Version of Yourself by Susan Hardwick-Smith MD https://www.amazon.com/Create-Her-Healthiest-Version-Yourself/dp/1637636644/ref=sr_1_3?s=books&sr=1-3

    Dr. Gabrielle Lyon with Amy Pearlman Podcast

    https://bit.ly/3TcVgvB

    Connect with Dr. Susan Hardwick-Smith

    Website: drsusan.com

    YouTube: https://www.youtube.com/@drsusan

    Instagram: https://www.instagram.com/drsusanofficial

    TikTok: https://www.tiktok.com/@drsusanofficial

    Facebook: https://www.facebook.com/drsusanofficial/

    LinkedIn: https://www.linkedin.com/in/drsusanhardwicksmith/

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    Timestamps:

    00:00 - Introduction: testosterone in women

    03:00 - Eighteen years in OB-GYN and the practice she left

    04:57 - Thirty years in medicine, zero training on testosterone

    06:40 - 31 FDA-approved products for men, zero for women

    07:35 - Why women produce more testosterone than estrogen

    09:20 - What the ovaries stop making at menopause

    10:18 - Testosterone reading zero five years early

    11:41 - Low testosterone symptoms in women

    13:22 - Intrinsa, the 2004 patch the FDA turned down

    19:04 - Off-label prescribing and what FDA approval means

    21:35 - Cognition, breast cancer, muscle and bone

    25:33 - Osteoarthritis and the anti-inflammatory theory

    26:31 - Dosing fears: hair loss, acne, voice changes

    28:16 - Why gels are dosed ten times higher

    32:14 - The 2019 international consensus

    34:00 - Dividing a 50 mg tube by ten

    38:18 - The Baylor study: pellet versus gel at six weeks

    40:13 - Safety data from fifty years of transgender care

    45:03 - Eight years of high dosing and what it cost

    46:16 - Lab reference ranges versus optimal ranges

    48:28 - ELISA versus LC-MS, and what the study found

    51:07 - Why free testosterone is calculated, not measured

    57:58 - Tachyphylaxis and chasing the number

    1:01:39 - Pellets, BioTE and where the reputation came from

    1:06:33 - Delivery methods, cypionate and enanthate

    1:11:47 - Whether anything raises testosterone naturally

    1:13:03 - DHEA at 100 mg and what it moved

    1:17:07 - Drugs that lower testosterone in women

    1:20:55 - Closing thoughts on dosing and access

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    8 September 2026, 1:00 pm
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