• 25 minutes 13 seconds
    The Truth About Testosterone in Women

    You say "steroids" and picture a baseball scandal, a jacked guy, a bad spray tan. But cortisol is a steroid. Estrogen is a steroid. The cream you put on poison ivy is a steroid. The word covering all of them is also covering testosterone therapy for women, and that collision is quietly costing women muscle and bone they don't have to lose.

    In this solo episode, prompted by a magazine interview on steroid use in women, Dr. Gabrielle Lyon breaks down what these molecules actually are, what they do inside a cell, and why the line between medicine and misuse has nothing to do with the word "steroid."

    Study and References:

    The Effects of Supraphysiologic Doses of Testosterone on Muscle Size and Strength in Normal Men (Bhasin et al., NEJM 1996) - https://pubmed.ncbi.nlm.nih.gov/8637535/

    Testosterone Enhances Estradiol's Effects on Postmenopausal Bone Density and Sexuality (Davis et al., 1995) - https://pubmed.ncbi.nlm.nih.gov/7616872/

    Global Consensus Position Statement on the Use of Testosterone Therapy for Women (2019) - https://pubmed.ncbi.nlm.nih.gov/31498...

    ISSWSH Clinical Practice Guideline for the Use of Systemic Testosterone for HSDD in Women (2021) - https://pubmed.ncbi.nlm.nih.gov/33814...

    The Global Epidemiology of Anabolic-Androgenic Steroid Use: A Meta-Analysis (Sagoe et al., 2014) - https://pubmed.ncbi.nlm.nih.gov/24582...

    What Is the Prevalence of Anabolic-Androgenic Steroid Use Among Women? A Systematic Review (Piatkowski et al., Addiction, 2024) - https://onlinelibrary.wiley.com/doi/1... "

    The Compounds for Females Are Really Commonly Faked!": Women's Challenges in Anabolic Steroid Acquisition (Piatkowski et al., Drug and Alcohol Review, 2024) - https://onlinelibrary.wiley.com/doi/1...

    Explore More from Dr. Gabrielle Lyon:


    📱 Connect with Dr. Gabrielle Lyon:

    Instagram: https://bit.ly/4uk9adc

    TikTok: https://bit.ly/3OFK3kJ

    X.com: https://bit.ly/4l3YlaX

    Facebook: https://bit.ly/3MBrJso

    LinkedIn: https://bit.ly/3N1nrdL

    Website: https://bit.ly/3NdV2kT

    Books: https://bit.ly/4r6ugZK

    Newsletter: https://bit.ly/402QCAj

    📺 Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

    YouTube: https://bit.ly/4boCFC3

    Spotify: https://bit.ly/4cWTbLG

    ⏰ Chapters:

    00:00 - Beginning

    01:25 - Introduction: The Sister Who Says "Oh My Gosh, You're Taking Steroids" Why Medicine Needs a Shared Vocabulary

    03:43 - What a Steroid Actually Is: Four Rings of Carbon

    04:49 - Anabolic vs. Androgenic: Same Receptor, Different Effects

    06:16 - A Brief History: From Wasting Disease to the Weight Room

    08:59 - Restoring vs. Exceeding: Why the Range Is the Whole Game

    11:38 - The Davis Trial: Testosterone, Bone Density, and Lean Mass

    13:38 - Oral Compounds, the Liver, and Why Conversion Matters

    14:20 - What Gets Sold Isn't What's Labeled: The Australian Drug-Checking Data

    15:31 - The 1.6% vs. 4% Myth: Reading the Prevalence Data Correctly

    18:33 - Why GLP-1s Are Pushing Women Toward Androgens

    20:26 - Permanent Effects: Voice Changes and What the Literature Shows

    21:33 - The Four Questions to Ask Before Any Androgen Conversation

    24:25 - Closing: Entering the Sarcopenia Era

    ‼️ Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    17 September 2026, 1:00 pm
  • 1 hour 46 minutes
    Fathers Lose Testosterone When They Raise Their Kids | Aldrich Chan, Psy.D.

    Most people assume becoming a parent is an emotional change, but a measurable part of it is hormonal, and it happens in fathers too. I sat down with Aldrich Chan, Psy.D., to talk about what changes in the brain, why the split we draw between mind and body does not hold up, and what decides whether stress reads as manageable or overwhelming when the hormones are identical either way.

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    Get Aldrich Chan’s books here:

    https://www.drchancnc.com/books

    📱Connect with Aldrich Chan, Psy.D

    Website: https://www.drchancnc.com/

    YouTube: www.youtube.com/@draldrichan

    Instagram: https://www.instagram.com/draldrichan

    Facebook: https://www.facebook.com/draldrichan

    LinkedIn: https://www.linkedin.com/in/draldrichan/

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    📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

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    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    00:00 - Introduction: what a neuropsychologist measures

    03:25 - Mild cognitive impairment and proactive interference

    04:52 - The SAD theory: separation, alienation, discord

    06:30 - The default mode network and 46.9% mind wandering

    08:56 - Reframing ADHD as an evolutionary advantage

    18:21 - Evolutionary mismatch and hunter-gatherer comparisons

    21:03 - Neuroplasticity, epigenetics, and the 24-hour timeline

    24:29 - Mind-body dualism and the gut-brain connection

    31:31 - What fatherhood does to the brain and testosterone

    36:47 - Choice overload and the four-bit working memory limit

    39:54 - Temporal discounting and building immediate feedback

    43:23 - Vital signals and how to identify a core value

    49:49 - Intuition, somatic markers, and the vmPFC

    55:00 - The 20-watt brain versus a 10-gigawatt supercomputer

    01:02:58 - Only 35% of the brain is built at birth

    01:06:13 - Creativity, nothingness, and the fear of uncertainty

    01:16:31 - Process, flow states, and the jazz pianist studies

    01:22:53 - Mirror neurons, group selection, and the rat experiments

    01:34:20 - Eustress and the line between moderate and major stress

    01:44:39 - Alloparenting and what the Hadza numbers show

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

    15 September 2026, 1:00 pm
  • 24 minutes 36 seconds
    The Bone You Have At 50 Was Built Before You Turned 18

    You might think bone density is something you build slowly over a lifetime, but nearly all of your peak bone mass is set before age 18, in a four-year window most parents never see coming. In this solo episode I break down what happens to a child's skeleton during that window, what GLP-1 medications do inside a body that's still growing, and the protocol I'd want every parent to follow. Muscle and bone are not what a body has they're what a body was built to become.

    In this solo episode, Dr. Gabrielle Lyon breaks down the science of bone health in children, adolescent GLP-1 use, and muscle building in kids:

    • Why the four years around age 12 in girls and 14 in boys account for close to 40% of the total bone mineral a person will carry for life
    • Why a hip fracture in a healthy 29-year-old is almost always a story about a childhood building phase that never happened, often tied to a history of restriction like anorexia
    • What semaglutide and other GLP-1 medications do inside a still growing skeleton, and why no long term bone density data exists for adolescents on these drugs
    • Why a JAMA Network Open trial found the group combining liraglutide with resistance training lost the most weight with bone mineral density statistically unchanged, while the drug alone caused bone loss
    • The complete protocol for parents: track strength and function over the scale, muscle strengthening and bone loading exercise three days a week each, protein at breakfast, and a screen time floor instead of a ceiling

    Muscle and bone are not what a body has; they are what a body was built to become, and childhood is the only window that bone accrual and muscle development happen. Understanding pediatric bone health, sarcopenia in children, and the real research on GLP-1s and adolescents is the difference between guessing with your child's skeleton and protecting it on purpose.

    Study and References:


    Thank you to our sponsors:


    Explore More from Dr. Gabrielle Lyon


    Connect with Dr. Gabrielle Lyon:


    Chapters

    00:00 - Introduction

    00:44 - The 29-Year-Old Who Fractured Her Hip

    01:20 - Muscle and Bone Are Childhood Assets

    03:01 - The Question I Keep Getting From Patients

    03:39 - The 30-Year Lifting Debate Is Over

    04:23 - Sarcopenic Obesity: More Muscle, Less Strength

    07:01 - What a Mouse Model Reveals About Muscle Potential

    08:24 - Screens: What the Data Shows

    10:00 - Food, Sleep, and the Screen-Weight Loop

    12:38 - GLP-1s in Teens: The STEP TEENS Trial

    13:52 - The Muscle Framing Mistake Everyone Makes

    16:49 - The Four-Year Window Bone Gets Built

    18:02 - The Trial That Proves Exercise Protects Bone

    20:29 - Prescribing Into an Unstudied Window

    20:46 - Why Lifting Doesn't Stunt Growth

    21:49 - Kids Get Stronger Without Building Muscle

    22:29 - The Protocol: What to Do Starting Today

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    10 September 2026, 1:00 pm
  • 1 hour 21 minutes
    The Testosterone Myth Women Have Been Lied To About │ Dr. Susan Hardwick-Smith

    You have probably been told that testosterone is a male hormone. Women produce more of it than estrogen, and for many of us it is the first hormone to go, sometimes reading zero five years before menopause while periods are still regular. Dr. Susan Hardwick-Smith and I get into what that costs you in muscle and bone, why there are thirty-one approved testosterone products for men and none for women, and what the number on your own lab report is measuring.

    Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe

    Create Her: Aging into the Healthiest Version of Yourself by Susan Hardwick-Smith MD https://www.amazon.com/Create-Her-Healthiest-Version-Yourself/dp/1637636644/ref=sr_1_3?s=books&sr=1-3

    Dr. Gabrielle Lyon with Amy Pearlman Podcast

    https://bit.ly/3TcVgvB

    Connect with Dr. Susan Hardwick-Smith

    Website: drsusan.com

    YouTube: https://www.youtube.com/@drsusan

    Instagram: https://www.instagram.com/drsusanofficial

    TikTok: https://www.tiktok.com/@drsusanofficial

    Facebook: https://www.facebook.com/drsusanofficial/

    LinkedIn: https://www.linkedin.com/in/drsusanhardwicksmith/

    Thank you to our sponsors:


    Explore More from Dr. Gabrielle Lyon


    Connect with Dr. Gabrielle Lyon:


    Timestamps:

    00:00 - Introduction: testosterone in women

    03:00 - Eighteen years in OB-GYN and the practice she left

    04:57 - Thirty years in medicine, zero training on testosterone

    06:40 - 31 FDA-approved products for men, zero for women

    07:35 - Why women produce more testosterone than estrogen

    09:20 - What the ovaries stop making at menopause

    10:18 - Testosterone reading zero five years early

    11:41 - Low testosterone symptoms in women

    13:22 - Intrinsa, the 2004 patch the FDA turned down

    19:04 - Off-label prescribing and what FDA approval means

    21:35 - Cognition, breast cancer, muscle and bone

    25:33 - Osteoarthritis and the anti-inflammatory theory

    26:31 - Dosing fears: hair loss, acne, voice changes

    28:16 - Why gels are dosed ten times higher

    32:14 - The 2019 international consensus

    34:00 - Dividing a 50 mg tube by ten

    38:18 - The Baylor study: pellet versus gel at six weeks

    40:13 - Safety data from fifty years of transgender care

    45:03 - Eight years of high dosing and what it cost

    46:16 - Lab reference ranges versus optimal ranges

    48:28 - ELISA versus LC-MS, and what the study found

    51:07 - Why free testosterone is calculated, not measured

    57:58 - Tachyphylaxis and chasing the number

    1:01:39 - Pellets, BioTE and where the reputation came from

    1:06:33 - Delivery methods, cypionate and enanthate

    1:11:47 - Whether anything raises testosterone naturally

    1:13:03 - DHEA at 100 mg and what it moved

    1:17:07 - Drugs that lower testosterone in women

    1:20:55 - Closing thoughts on dosing and access

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    8 September 2026, 1:00 pm
  • 16 minutes 7 seconds
    5 Protein Myths Your Doctor Is Still Repeating In The Exam Room

    You probably ate something today with high protein printed across the front of it, and there is a good chance it did almost nothing for your skeletal muscle. There is no meaningful enforcement standard for what the front of a package is allowed to promise, and the research points to a per meal threshold most of these products do not come close to touching. Here is the number, the five myths that have to come off the table first, and how to read any label in about five seconds.

    Thank you to our sponsors:

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    Chapters

    00:00 - Introduction: what a high protein label promises

    01:03 - Protein-ification and the labeling gap

    04:10 - Myth 1: protein and kidney function

    06:01 - Myth 2: the 0.8 gram RDA

    07:04 - Nitrogen balance and the 2026 guideline change

    07:45 - Where the clinical target lands above the RDA

    08:43 - Myth 3: acid ash and bone density

    11:01 - Myth 4: leucine and the per meal threshold

    12:12 - Four product categories in your pantry

    14:44 - The 25 to 30 gram complete protein rule

    15:08 - Myth 5: daily total versus per meal distribution

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    3 September 2026, 1:00 pm
  • 1 hour 45 minutes
    STOP Treating Low Testosterone As Depression: The 160 Reading Navy Doctor Refused | Tim Parlatore

    A Navy captain with 24 years of service went to medical for exhaustion, weight gain, and low mood, and was told to see a therapist and eat less. When he asked for a testosterone test his physician asked whether he had erectile dysfunction, and refused to order it when he said no. His level came back at 160; the cutoff we use in this country is 300. I've treated this population for 15 years, and roughly 27% of operators test below that number. Tim Parlatore is the attorney who wrote the Pentagon memo that now puts testosterone on the annual physical, and we get into what it says and why most men never have this hormone checked again after they leave pediatrics.

    Studies & References


    Support Kaczkowski Family's GoFundMe campaign


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    📱Connect with Tim Parlatore:

    Website: https://parlatorelawgroup.com/

    YouTube: https://www.youtube.com/channel/UCSSQE0_WrlegQk09nFi4QZw

    Instagram: https://www.instagram.com/tparlatore/

    Facebook: https://www.facebook.com/tparlatore

    X.com: https://x.com/timparlatore

    LinkedIn: https://www.linkedin.com/in/timothy-parlatore/

    🙌Thank you to our sponsors:

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    📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

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    📱Connect with Dr. Gabrielle Lyon:

    Instagram: https://bit.ly/4uk9adc

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    Facebook: https://bit.ly/3MBrJso

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    Books: https://bit.ly/4r6ugZK

    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    00:00 - Intro of show

    02:32 - Why military service lowers testosterone

    04:15 - Treated like an anabolic steroid

    06:52 - Screening first, not bodybuilding

    08:07 - 27% of operators test low

    09:34 - The three groups of users

    10:52 - The BUD/S student who died

    13:00 - A captain's testosterone was 160

    15:39 - Denied the test, then the wait

    18:58 - Why men skip baseline testing

    19:46 - Beyond operators: the wider force

    21:56 - The three effects on the force

    26:37 - The best biomarker for men

    27:40 - Why they wanted a study first

    29:04 - Health, media, and politics

    37:44 - Testing and treating women

    44:57 - Voluntary treatment and options

    48:20 - The friend Tim lost

    51:00 - Selling the science to the Pentagon

    53:00 - Building a research dataset

    1:05:29 - Naval Academy to defending Gotti

    1:11:54 - Trial as psychological warfare

    1:21:03 - The fitness turnaround

    1:26:02 - The email spying scandal

    1:31:06 - "I am the storm"

    1:35:32 - Prosecutorial misconduct

    1:41:11 - Secondary trauma and the human cost

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

    1 September 2026, 12:30 pm
  • 19 minutes 37 seconds
    Nobody Told You This About Creatine

    You might think creatine is a bodybuilder's steroid you have to cycle, load, and fear for your kidneys, but it's a compound your own body already makes from three amino acids, with one of the deepest safety records in all of nutrition science. The problem isn't the creatine; it's the noise around it.

    In this solo episode, Dr. Gabrielle Lyon discusses:

    • Why the bump creatine causes in your creatinine lab value is a metabolic artifact, not a sign of kidney damage in healthy people
    • Where the hair-loss fear came from. A single unreplicated study in one rugby player showing a 56% DHT rise, and why no research has ever directly linked creatine to hair loss
    • How men and women respond differently (roughly 1.5 kg of lean mass in men vs. about a third of a kilogram in women), and why women still gain real strength, grip, cognition, and recovery
    • Why you can't realistically eat your way to 5 grams a day: it would take 2.5 to 3 pounds of cooked meat and fish daily, so a single scoop closes the gap
    • The protocol: 3–5 grams of plain monohydrate every day, no loading phase, no cycling, timing barely matters

    Muscle is your organ of longevity, the tissue that clears most of the glucose in your bloodstream and defends your metabolism as you age. Creatine won't build it for you, but it raises the ceiling on the work you can do, so the training that protects that muscle pays off more. Understanding what's real and what's fearmongering is the difference between avoiding a proven tool and using it well.

    Studies & References


    Thank you to our sponsors:


    Explore More from Dr. Gabrielle Lyon


    Connect with Dr. Gabrielle Lyon:


    Chapters

    00:00 - Introduction

    02:47 - What Creatine Is and Isn't

    03:24 - The Phosphocreatine Energy System

    04:22 - Lean Mass: Water and Training Capacity

    05:08 - Men vs Women Respond Differently

    06:29 - Vegans, Older Adults, and Sarcopenia

    07:11 - Creatine and the Brain

    08:53 - The Real Safety Profile

    09:31 - The Kidney and Creatinine Myth

    09:57 - The 56% DHT Hair Loss Claim

    10:37 - Contraindications and Screening

    12:19 - Why You Can't Eat Enough Creatine

    14:26 - Muscle-Centric Medicine

    16:44 - How to Dose It Correctly

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    27 August 2026, 1:00 pm
  • 1 hour 12 minutes
    Are You Aging Faster Than You Should? - Dr. Kristen Holmes

    Most of what we call "aging" may not be about time at all. It may be a nervous system stuck in stress, quietly draining your sleep, your recovery, and your long-term health.

    In this episode, Dr. Gabrielle Lyon sits down with Dr. Kristen Holmes to discuss:

    • Why the hallmarks of aging- inflammation, mitochondrial dysfunction, cellular decline may be symptoms of a dysregulated autonomic nervous system, and how much of your HRV (47–65%) is genetic versus trainable
    • How your sleep is decided during the day, not at night, and why perceiving your day as "threatening" keeps your HRV suppressed and robs you of deep, restorative sleep
    • The circadian "amplitude" formula for bright days and dark nights that predicts everything from menopause symptom severity to longevity, plus the ~90 minutes of natural light almost no one gets
    • Why late-night eating rivals alcohol for damaging your resting physiology, and how a simple 12-hour eating window gets you most of the way there
    • Why the fittest people sleep less, and how all-day movement and "exercise snacks" beat a single gym block

    When you understand that your nervous system sits underneath your sleep, energy, and pace of aging, you stop chasing fragmented fixes and start pulling the few daily levers light, movement, meal timing, consistency that move the needle.

    Studies & References


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    Listen to “The Line” on all your favorite platforms!

    YouTube: https://www.youtube.com/@TheLine-Podcast

    Apple Podcasts: https://podcasts.apple.com/us/podcast/the-line-with-dr-kristen-holmes/id1846864184

    Spotify: https://open.spotify.com/show/3zc3BCKHlFAlffRnd6kZXy

    Get Dr. Kristen Holmes’s book, “Aligned” here: https://sites.prh.com/dr-kristen-holmes

    📱Connect with Dr. Kristen Holmes:

    Website: https://drkristenholmes.com/#top

    YouTube: https://www.youtube.com/@TheLine-Podcast

    Instagram: https://www.instagram.com/drkristenholmes/

    LinkedIn: https://www.linkedin.com/in/kristen-holmes/

    🙌Thank you to our sponsors:

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    📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

    YouTube: https://bit.ly/4boCFC3

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    📱Connect with Dr. Gabrielle Lyon:

    Instagram: https://bit.ly/4uk9adc

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    Facebook: https://bit.ly/3MBrJso

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    Website: https://bit.ly/3NdV2kT

    Books: https://bit.ly/4r6ugZK

    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    00:00 - Intro of show

    02:44 - Two types of people

    03:01 - Aging as nervous system dysregulation

    04:49 - The stellate ganglion block and trauma

    07:34 - How much of HRV is genetic

    11:13 - Emotions of trust versus fear

    16:57 - Threat versus challenge appraisal

    19:20 - Why modern life breaks your biology

    23:24 - Structuring travel around sleep

    26:16 - Circadian amplitude and contrast

    28:00 - Amplitude and menopause symptoms

    30:17 - What heart rate variability means

    32:34 - Biggest levers for perimenopause

    37:04 - Light dose and exercise snacks

    40:18 - Why fit people sleep less

    44:34 - Cycle syncing and training

    51:56 - Meal timing and late-night eating

    55:55 - Sleep-wake consistency and aging

    59:43 - Exercise timing and pregnancy

    01:04:54 - Why behavior precedes thought

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

    25 August 2026, 1:00 pm
  • 20 minutes 41 seconds
    The Gut Yeast That Brews Ethanol From Every Carb You Eat

    Blowing four times the legal limit on a breathalyzer usually means one thing, but in 2015, a judge dismissed a DWI because the driver's own gut was fermenting alcohol from an ordinary carb-heavy dinner. It's called auto-brewery syndrome, and the fuel it runs on is the same load your muscle is supposed to be clearing from your blood.

    In this solo episode, Dr. Gabrielle Lyon discusses:

    • How gut yeast overgrowth turns everyday carbs like pasta, bread, and rice into ethanol that registers as real intoxication, brain fog, dizziness, and all
    • The specific risk factors that open the door: dysbiosis, SIFO, repeated antibiotic use, and poorly controlled diabetes or fatty liver
    • The three-part protocol to correct it, reduce the yeast burden, remove the carbohydrate fuel, and rebuild the microbiome, plus the carbohydrate challenge test, most doctors never run
    • Why skeletal muscle is your body's primary site for clearing blood sugar, and how an under-muscled body drifts into the same insulin-resistant, dysbiotic state that lets fermentation take hold

    Whether or not you'll ever face this rare diagnosis, you'll walk away understanding that gut health and muscle health share one supply chain and that defending your muscle is how you starve the problem at its root.

    Study & References:

    Woman beats DWI — her body brews alcohol (CBS News, 2015): https://www.cbsnews.com/news/woman-beats-dwi-with-rare-defense-her-body-brews-alcohol/

    Cordell & McCarthy (2013), Int. J. Clin. Med. — foundational U.S. case study: https://doi.org/10.4236/ijcm.2013.47054

    Malik, Wickremesinghe & Saverimuttu (2019), BMJ Open Gastroenterology: https://doi.org/10.1136/bmjgast-2019-000325

    Painter, Cordell & Sticco — Auto-Brewery Syndrome, StatPearls (NIH): https://www.ncbi.nlm.nih.gov/books/NBK513346/

    Thank you to our sponsors:

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    Explore More from Dr. Gabrielle Lyon


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    Chapters

    00:00 - Introduction

    01:06 - The 2015 DUI dismissed in court

    01:39 - Auto brewery syndrome defined

    03:10 - The 2013 brewer's yeast case

    03:46 - Why the evidence is thin

    04:37 - How gut yeast ferments carbs

    06:45 - Five conditions that trigger it

    07:21 - SIFO vs SIBO explained

    08:12 - Antibiotics and metabolic disease

    10:00 - The carbohydrate challenge test

    11:07 - Three non-negotiable treatments

    12:53 - Muscle: the metabolic sink

    15:07 - The under-muscled phenotype

    17:03 - Your four directives

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    20 August 2026, 1:00 pm
  • 1 hour 8 minutes
    The 1 Macronutrient High Performers Skip After 60 | Arthur Brooks, PhD

    Most people chase happiness as a feeling and wait for certainty before making big decisions, and both instincts quietly backfire. Dr. Arthur Brooks joins Dr. Gabrielle Lyon to break down what happiness is and how to act on it.

    In this episode, Dr. Gabrielle Lyon and Dr. Arthur Brooks discuss:

    • The three "macronutrients" of happiness - enjoyment, satisfaction, and meaning, and why pursuing pleasure alone leads to detox, not happiness
    • A usable rule for any hard decision: aim for roughly 80% excitement, 20% fear, and near-zero "deadness" once you have about 80% situational awareness
    • Why solo pleasures don't stick if you're doing it alone, you're probably doing it wrong, and how enjoyment requires people plus memory
    • How GLP-1s, SSRIs, and hormonal shifts can dull motivation, reward, and desire, and why knowing this gives you power over it
    • Simple tech protocols: phone-free first hour, meals, and last hour that protect oxytocin, meaning, and connection

    Understand happiness as something you build rather than something you wait to feel, and you walk away with concrete tools to decide better, connect deeper, and stop mistaking achievement for love.

    Want ad-free episodes? Subscribe to Forever Strong Insider: https://bit.ly/4u5VSRe

    Listen to “Office Hours” on all your favorite platforms!

    YouTube: https://www.youtube.com/playlist?list=PLDksUNNE9g_ZC6YJ3eG9lhZrMOG6IVuGR

    Apple Podcasts: https://podcasts.apple.com/no/podcast/office-hours-with-arthur-brooks/id1832119842

    Spotify: https://open.spotify.com/show/3fT0FLFsPgV2mbVjuOo3JV?si=e4d69f6725194d48

    Get Dr. Arthur Brooks’ books here: https://www.arthurbrooks.com/books

    📱Connect with Arthur Brooks:

    Website: https://www.arthurbrooks.com/

    YouTube: https://www.youtube.com/@drarthurbrooks

    Instagram: https://www.instagram.com/arthurcbrooks/

    Facebook: https://www.facebook.com/ArthurBrooks/

    X.com: https://x.com/arthurbrooks

    LinkedIn: https://www.linkedin.com/in/arthur-c-brooks/

    🙌Thank you to our sponsors:

    Ladder - If you have an iPhone, head to https://bit.ly/4ggxfLK and take a quick quiz to find your perfect Ladder plan. Use my link and get a free 7-day trial with NO credit card, and $10 off your first month if you join.

    Timeline - up to 20% off when you subscribe and save at https://bit.ly/45xd870

    Bon Charge - Save 15% at https://bit.ly/4ga6aJZ with code DRLYON

    Lucy - Get 20% off your next order with code DRLYON at https://bit.ly/45Zz9eP, or find yours in store at https://bit.ly/4xyELIS

    📺Watch the “Dr. Gabrielle Lyon Show” every Tuesday at 9AM EST:

    YouTube: https://bit.ly/4boCFC3

    Spotify: https://bit.ly/4cWTbLG

    📱Connect with Dr. Gabrielle Lyon:

    Instagram: https://bit.ly/4uk9adc

    TikTok: https://bit.ly/3OFK3kJ

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    Facebook: https://bit.ly/3MBrJso

    LinkedIn: https://bit.ly/3N1nrdL

    Website: https://bit.ly/3NdV2kT

    Books: https://bit.ly/4r6ugZK

    Newsletter: https://bit.ly/402QCAj

    ⏰Timestamps:

    00:00 - Intro of show

    02:14 - Enjoyment, satisfaction, and meaning

    02:55 - Pleasure vs enjoyment

    05:04 - Why strivers can't enjoy life

    07:05 - The four affect profiles

    13:46 - Meaning: the protein of happiness

    14:26 - Satisfaction and struggle

    18:10 - Suffering equals pain times resistance

    23:57 - The mistakes that sabotage happiness

    28:12 - How to make hard decisions

    30:00 - Excitement, fear, and deadness

    33:39 - GLP-1s, motivation, and desire

    36:08 - SSRIs, birth control, and attraction

    38:00 - The meaning crisis and screens

    41:25 - Boredom and the shock experiment

    43:07 - Tech-free protocols

    49:50 - Transcendence and daily practice

    56:35 - The striver's lament

    57:44 - Why love can't be earned

    1:02:42 - Falling in love, and staying in love

    ‼️Disclaimer: The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    This episode includes paid sponsorships.

    18 August 2026, 1:00 pm
  • 14 minutes 8 seconds
    Why You're So Bloated on Ozempic

    You might think the number dropping on the scale is the whole win, but on a GLP-1, a meaningful share of what you're losing may be muscle, not fat, and the fiber that's supposed to help can quietly make things worse.

    In this solo episode, Dr. Gabrielle Lyon discusses:

    • Why 25–40% of the weight lost on GLP-1 medications can be lean mass, and how to protect your muscle with adequate protein (1.2–1.5 g/kg) and resistance training
    • The GLP-1 fiber paradox and why these drugs need fiber to work, but make it hard to tolerate, and why 40–70% of patients hit GI side effects like bloating and constipation
    • When to fiber max vs. fiber mine, plus how to reintroduce fiber gradually so you get the gut benefits without the bloat, bezoars, or obstruction risk

    Get this balance right, and you keep your muscle, calm your gut, and let the medication do its job instead of ending up bloated, constipated, and quietly losing strength.

    Thank you to our sponsors:

    • Square - Get up to $200 off Square hardware when you sign up at square.com/go/drlyon
    • BodyHealth - Use the code LYON20 to get 20% off your first order https://bit.ly/3TJVSsv
    • Upgrade your kitchen with Our Place today. Visit https://bit.ly/4q3ggRp and use code DRYLON for 10% off sitewide. That’s F-R-O-M-O-U-R-P-L-A-C-E DOT COM / D-R-L-Y-O-N and use code DRLYON for 10% off sitewide. With a 100-day trial, you can try it completely risk-free.
    • Branch Basics - Get 15% off the Premium Starter Kit at https://bit.ly/4q3ZYb4 with the code DRLYON.

    Explore More from Dr. Gabrielle Lyon


    Connect with Dr. Gabrielle Lyon:


    Chapters

    00:00 - Introduction

    00:46 - The pear bezoar and bowel obstruction

    02:07 - Why 95% of Americans fall short

    03:32 - The GLP-1 fiber paradox

    04:18 - Why GLP-1 drugs make fiber hard to eat

    05:50 - How GLP-1s slow the gut

    07:40 - Bezoars, psyllium, and the 87-case series

    09:12 - Fiber as therapy: titrating it right

    10:03 - The muscle loss problem

    11:28 - Getting the fiber and GLP-1 balance right

    If you found this episode valuable, share it with someone who would benefit from it.

    Disclaimers: This episode includes paid sponsorships.

    The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked from this podcast or YouTube is at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professional for any such conditions.

    13 August 2026, 1:00 pm
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