Drs. Karl and Spencer discuss the brand new 3 year study of tirzepatide in those with prediabetes along with a discussion on semaglutide treating osteoarthritis.

Learn:

• If people lose weight and keep it off with tirzepatide
• How many people regain weight after stopping the medicine
• Long-term side effects
• If semaglutide helps with osteoarthritis

Click here to read the tirzepatide study

Click here to read the semaglutide study

Drs. Karl and Spencer invite Dr. Andrea Love back to the podcast to discuss a recent Joe Rogan podcast with Calley and Casey Means along with the concept of Make America Healthy Again and RFK jr.

Learn:

What the docs agree with.

What they don't agree with.

Is raw milk okay?

Are cancer rates rising?

and more

Follow Dr. Andrea here 

https://www.instagram.com/dr.andrealove

Drs. Karl and Spencer discuss all things cortisol and poke fun at the influencers who try to fear monger exercise due to cortisol increases.

Learn:

What is cortisol and what does it do?

Is  cortisol bad?

Should you worry about cortisol increases with exercise?

Should you take supplements to lower cortisol?

and more

Drs. Karl and Spencer discuss their ideal healthcare delivery system.

Learn:

Spencer's journey building and selling Sequence and what he wants to do next.

How Dr. Karl believes healthcare should be and what he's doing next.

Click here to get on Dr. Spencer's waitlist

Drs. Karl and Spencer discuss BS supplements claiming to be like Ozempic along with discuss some new obesity drugs coming down the pipeline that were announced in phase 1 and 2 trials.

Are there any supplements that can mimic Ozempic?

What is amylin and how does it help with weight and sugars?

What is this new oral drug "amycretin" in phase 1 trials?

and more

Drs. Karl and Spencer chat with Dr. Jen Gunter all about menopause.

Learn:

How it's diagnosed.

When and when not to treat.

The various treatment.

If it is indicated for cardiovascular disease prevention or body composition.

Whether or not you should get labs.

See more at Dr. Gunter's website 

Drs. Karl and Spencer talk about the top line results from study showing liraglutide may have some benefit in Alzheimer's along with top line results from the Summit trial showing heart failure benefits with tirzepatide.

They also discuss the women's boxing controversy and BMI in athletes.

Drs. Karl and Spencer chat with return guest and bone expert endocrinologist Dr. Rachel Pessah-Pollack all about the new Vitamin D guidelines.

Should healthy people even check a vitamin D level?

Should they supplement with vitamin D?

What people should check or supplement?

Click here for the new guidelines 

Does semaglutide cause blindness?

What is NAION (nonarteritic anterio ischemic optic neuropathy)?

What about worsening of diabetic retinopathy with semaglutide?

What can you do to minimize the risk of NAION and retinopathy?

Get the full study here

Read Dr. Brugger's blog

Tirzepatide may be a good option if you have obesity and obstructive sleep apnea.

Click here to read the study

Click here to read about the gastric ablation and trial.

Click here to see Dr. McGowan's clinic