Today we’re talking about blood pressure.

Most of us know that high blood pressure is bad — but surprisingly few of us understand what it actually means, how widely it affects the body, or how to keep it under control.

The good news is that monitoring blood pressure is easier than ever, putting you in a strong position to spot problems early and take meaningful action.

Professor Tim Spector joins me to explain what blood pressure is, why it matters so much, and share some top salt-based tips that can have a powerful impact on long-term health.

🌱 Try our science-backed and tasty wholefood supplement Daily 30+

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Free resources from ZOE

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

How quickly can you improve your gut health? Can diet help lower your risk of dementia? And what should you know about food labels and healthy weight loss? In this special live Q&A, Prof Tim Spector, Prof Sarah Berry and Dr Federica Amati answer your biggest nutrition questions and share practical, evidence-based advice you can use today.

Drawing on decades of research and data from hundreds of thousands of people, they explain how diet can influence the gut microbiome, brain health, hunger, energy levels and long-term health. They discuss dementia risk, healthy snacking, intermittent fasting, ultra-processed foods, plant diversity, breakfast, food labels and the latest science on weight loss.

You’ll learn how quickly the gut microbiome may respond to dietary change, why some foods keep you fuller for longer, how to build a healthier breakfast, and simple ways to make better food choices. The team also explain why small dietary changes can have lasting benefits.

If your daily food choices influence your gut health, brain health and future wellbeing, which change is worth making first?

🌱 Try our science-backed and tasty wholefood supplement Daily30

🌿Let your gut microbes snack on the ZOE Gut Health Bar

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

Timecodes

00:00 Intro

01:56 The first ever live ZOE podcast

09:14 How long does it really take to improve your gut microbiome?

12:56 Can you feel healthier before your gut microbiome changes?

14:15 Which foods should you always buy organic?

16:33 Are oats actually healthy?

18:36 The overnight oats trick that may improve blood sugar

19:28 Resistant starch: the hidden nutrient most people miss

21:32 Always hungry at 3pm? Sarah’s evidence-backed fix

27:17 The food industry trick that makes you eat more

29:44 Why ultra-processed foods leave you hungry

30:50 Does chewing more food really help you lose weight?

33:23 What does gut health have to do with depression and anxiety?

37:45 Is your gut controlling your brain?

39:34 Are fermented foods the most underrated brain-health food?

41:46 Starting Ozempic or Wegovy? Do this first

42:40 What do GLP-1 drugs do to your gut microbiome?

45:20 Tim Spector’s plan to fix Britain’s health crisis

47:55 Why governments still aren’t acting on ultra-processed foods

50:50 Have US food guidelines changed—and is the UK falling behind?

53:08 Is intermittent fasting safe for women?

56:15 What’s the healthiest breakfast to break a fast?

58:20 The science breakthroughs that could change nutrition forever

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

The Appetite Reset by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Good Mood Food (preorder) by Prof. Tim Spector

Free resources from ZOE

The Smart Snacking Guide: How to feed your gut, fuel your day, and snack without guilt

The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

Mentioned in today's episode

Daily Sampling Reveals Personalized Diet-Microbiome Associations in Humans, Cell Host & Microbe (2019)

ZOE’s PREDICT studies: What we’ve learned

ZOE snacking study: What should you do?

The Big IF Study: What did we find?

Diet and Dementia, Neurology (2024)

Daily30: Does it work?

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

Today, we’re talking about supplements.

We’ve all seen them; the multivitamins, the fortified foods, the neatly packaged powders promising improved energy, immunity and longevity. 

Supplements boast bold claims, however, it’s hard to know if they’re genuinely helpful or just well-marketed.

Professor Tim Spector and Professor Sarah Berry join me to unpack why supplements exist, what the science really says about their benefits and risks, and how to decide if supplements deserve a place in your daily routine.

🌱 Try our science-backed and tasty wholefood supplement Daily 30+

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Free resources from ZOE

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

Have feedback or a topic you'd like us to cover? Let us know hereListen to the full episode here

Ozempic, Wegovy and Mounjaro can help people lose weight. But what should you eat on GLP-1 drugs to avoid side effects, protect muscle, and maintain results long term?

In this episode, Dr Federica Amati, ZOE’s Head Nutritionist and author of The Appetite Reset, explains how these drugs work, why many people struggle with side effects, and why losing weight does not automatically mean better health.

You’ll learn why the weight lost may not be fat, why nutrient deficiencies, dehydration and muscle loss can become a risk, and what to eat before, during and after treatment. Federica shares four practical principles to help reduce side effects, protect lean mass, improve diet quality and support long-term health whether you stay on these medications or eventually stop taking them.

Millions of people are now using GLP-1 drugs. But if these medications reduce appetite so effectively, how do you make sure your body still gets the nutrients it needs?

🌱 Try our science-backed and tasty wholefood supplement Daily30

🌿Let your gut microbes snack on the ZOE Gut Health Bar

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

Timecodes

00:00 Intro

03:23 What Ozempic actually does inside your body

06:00 Are Ozempic and Mounjaro really miracle drugs?

10:53 Ozempic vs Wegovy vs Mounjaro: what’s the difference?

11:40 The step almost everyone skips before starting GLP-1s

13:16 Why do some people get worse Ozempic side effects?

15:20 The surprising brain effect changing people’s lives

18:20 The appetite system most people never learn about

21:25 How fibre helps your body make more GLP-1 naturally

24:24 Why ultra-processed foods never keep you full

27:20 Why staying a healthy weight is harder than ever

30:11 The hidden risk nobody mentions when losing weight

32:11 The 4 rules to protect muscle, bones and brain health

34:24 The side effect that can make life feel less enjoyable

35:26 What happens if you stay on Ozempic but never change your diet?

38:16 Can Ozempic cause malnutrition? Warning signs to know

39:35 Why some people suddenly stop craving junk food

41:15 What should you eat before starting Ozempic?

42:50 What should you eat while taking Ozempic?

44:01 Why meal timing matters more than you think

46:25 The eating mistake that triggers nausea and vomiting

47:18 The best protein foods for GLP-1 users

49:15 Can Ozempic cause muscle loss? The protein myth explained

51:40 What should you eat when coming off Ozempic?

53:15 Why some people keep the weight off for years

57:45 Why do most people quit Ozempic within a year?

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

The Appetite Reset by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Good Mood Food (preorder) by Prof. Tim Spector

Free resources from ZOE

The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

Mentioned in today's episode

The Appetite Reset by Dr Federica Amati

GLP-1 Discontinuation Among Patients, Diabetes and Endocrinology (2024)

How much protein do you need? ZOE’s new guide

Managing Gastrointestinal Adverse Events in Patients Treated with GLP-1s, Journal of Clinical Medicine (2022)

Neurological complications following GLP-1 use, BMC Neurology (2025)

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

Today we’re talking about what causes ageing.

Here’s an important term you may not have heard before: inflammaging. It describes the link between chronic inflammation in the body and accelerated ageing.

While it’s relatively unknown, this process is one of the most important concepts to understand if we want to live longer, healthier lives.

I’m joined by Professor Janet Lord to break down what inflammaging is, why it’s one of the biggest threats to healthy longevity, and the surprisingly simple, science-backed habits we can all use to slow it down.

🌱 Try our science-backed and tasty wholefood supplement Daily 30+

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Free resources from ZOE

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

Have feedback or a topic you'd like us to cover? Let us know here

Listen to the full episode here

Could inflammation be causing low mood, anxiety, depression, or even affecting your risk of dementia? 

Emerging science suggests that inflammation in the body may change how the brain works. In this episode, Ed Bullmore, a Professor of Psychiatry at King's College London and a leading voice in brain research, explores why feeling low, emotionally flat, foggy or exhausted may not always be “all in your head”.

Ed explores emerging science suggesting that inflammation in the body may alter how the brain works. He explains how inflammation can influence the brain and discusses why obesity, gut health, gum disease, menopause, ageing and stress may all play a role. He also examines why medicine has traditionally separated physical and mental health, and what this may mean for understanding the root causes of low mood.

By the end of the episode, you’ll have some practical ways to support both brain and body health. Ed shares the evidence behind which exercise and diet matter most, and why discussing mental and physical health together may help you get closer to the causes of your symptoms.

If your mood, energy and brain health are shaped by more than what’s happening in your mind, what might your body be trying to tell you?

🌱 Try our science-backed and tasty wholefood supplement Daily30

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

Today we’re talking about skin and sunlight.

Skin and sunlight have a complicated relationship. Sunlight helps our bodies produce vitamin D, which is essential for overall health. However, too much exposure can accelerate skin ageing and increase the risk of skin cancer.

So how much sun is enough? Are most of us getting too little, or too much? And where does sunscreen fit into a healthy daily routine?

I’m joined by Professor John McGrath to explore how sunlight affects our skin, and how to strike the perfect balance

🌱 Try our science-backed and tasty wholefood supplement Daily 30+

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.
📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Free resources from ZOE

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

Have feedback or a topic you'd like us to cover? Let us know here

Listen to the full episode here

Could mushrooms hold the secret to better gut health, lower cholesterol, and can they protect your brain?

Today, Professor Robin May, a leading microbiologist and the UK Government’s Chief Scientific Officer, explores why our interest in mushrooms has exploded. He explains why they are not just another vegetable but could hold the key to better gut health, brain health, immune health, and lower cholesterol.

By the end of the episode, you’ll know which health claims about mushrooms are real, which are exaggerated and where the science is just too early to trust. You’ll have a solid understanding of what mushrooms are really doing inside our bodies and how to unlock the secret health powers they hold.

Should mushrooms become a regular part of your weekly shop rather than an occasional side dish? And if fungi have evolved alongside humans for millions of years, what else might they reveal about the future of nutrition and health?

🌱 Try our science-backed and tasty wholefood supplement Daily30

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

Timecodes

00:00 Intro

03:32 Are mushrooms closer to humans than plants?

06:20 What is a mushroom, really?

10:46 Why we’re eating more mushrooms now

12:14 The hidden nutrients inside mushrooms

13:56 Can mushrooms boost vitamin D?

15:35 The sunlight trick for healthier mushrooms

17:27 How many mushrooms give you enough vitamin D?

18:01 The mushroom with 500x more vitamin D

20:25 The mystery compound found in mushrooms

22:00 Should you take mushroom supplements?

24:30 Do all mushrooms contain this rare compound?

26:22 Can mushrooms help you live longer?

28:35 Can lion’s mane protect your brain?

30:24 Do mushrooms really boost IQ?

34:21 Can mushrooms affect your immune system?

36:40 How mushrooms feed your gut microbes

38:20 Should fungi live in your gut?

39:45 The fungus that lives on your head

41:50 Can mushrooms lower cholesterol?

43:21 Are you cooking mushrooms wrong?

45:25 Should you eat raw mushrooms?

47:21 How to make mushrooms taste better

49:25 The easiest way to eat more mushrooms

52:17 Robin’s top mushroom tip

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Good Mood Food (preorder) by Prof. Tim Spector

Free resources from ZOE

The Hormone Harmony Guide: Tuning Your Body’s Internal Orchestra

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

Mentioned in today's episode

A Review of Mushrooms as a Potential Source of Dietary Vitamin D, Nutrients (2018)

Ergothioneine: an underrecognised dietary micronutrient required for healthy ageing, British Journal of Nutrition (2023)

Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles?, Antioxidants and Redox Signaling (2022)

Mushrooms & longevity, Nature (2025)

Lion’s mane & nerve growth factor, Journal of Biological Engineering (2023)

The Relationship between Mushroom Intake and Cognitive Performance, Nutrients (2024)

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

Today we’re exploring the impact of ultra-processed foods on young people.

One of the big reasons ultra-processed foods have become so widespread is convenience. They offer quick, easy meals for people short on time - and few groups are more time-pressed than parents trying to feed young children.

But does this convenience come at a cost?

I’m joined by Harvard professor Dr Andy Chan, whose research is helping us understand how early exposure to ultra-processed food can shape future health.

🌱 Try our science-backed and tasty wholefood supplement Daily 30+

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Free resources from ZOE

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

Have feedback or a topic you'd like us to cover? Let us know here

Listen to the full episode here

If you feel like you can’t stop eating, constantly crave junk food, or struggle with overeating, this episode will change how you see food. 

Michael Pollan, one of the world's most influential science writers, joins Professor Tim Spector to explain how ultra-processed food may drive food addiction, override fullness signals, and keep us craving more. Together, they explore why foods high in sugar, salt, and fat can feel so hard to resist, and what we can do to fight back.

Michael and Tim unpack how the modern food system changed over the last 50 years, and why many ultra-processed foods are designed around “craveability.” They explain how these foods may stimulate the brain’s reward systems, why fibre and plants help us feel fuller, and why cooking more meals at home may help reduce overeating without calorie counting.

The episode includes practical ways to regain control of your eating habits, reduce cravings, feel better and live more healthy years.

If your cravings feel impossible to control, is it really a lack of willpower, or is modern food engineered to keep us coming back for more?

🌱 Try our science-backed and tasty wholefood supplement Daily30

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

Timecodes

00:00 Intro

04:04 How monoculture changed modern food

08:52 Are we basically made of corn?

12:58 The 3 ingredients engineered to drive cravings

14:32 Why ultra-processed food keeps you hungry

15:44 Why governments subsidize junk food

18:01 How fast food changed family cooking

20:00 Is ultra-processed food destroying family meals?

21:46 What happens when you stop eating plants? 22:55 Your gut microbes are eating too

25:31 Caffeine and the world’s most used drug

26:26 Michael Pollan quits caffeine for 3 months

28:35 Is caffeine addiction actually harmful?

29:11 Coffee and heart disease risk explained

32:34 Why workplaces normalized caffeine 33:40 The simplest way to stop overeating

35:30 Did food companies convince us cooking is hard?

37:02 How to identify ultra-processed food

38:25 Michael Pollan’s famous food rule explained

40:14 Why “plant-based” doesn’t always mean healthy

42:46 The Japanese habit that may reduce overeating

44:24 How food companies engineer craveability

45:25 Are food companies manipulating your cravings?

46:41 Why eating 30 plants a week matters

47:36 Eat food, not too much, mostly plants

Today we’re talking about wellness trends.

Social media has supercharged the wellness world, with new trends popping up and spreading faster than ever. It feels like we’re constantly being sold the next must-have product - each one a guaranteed route to better health that you simply can’t live without.

But how many of these trends are actually backed by science? And could some of them actually be doing more harm than good?

I’m joined by wellness expert Liz Earle and nutritional scientist Dr Federica Amati to separate evidence from exaggeration. From red light therapy to cow fat, they’ll reveal which trends are worth your time - and which are best left behind.

🌱 Try our science-backed and tasty wholefood supplement Daily 30+

Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE

Follow ZOE on Instagram.

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Ferment by Prof. Tim Spector

Free resources from ZOE

Eating for Better Brain Health: Your brain-gut blueprint

How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Better Breakfast Guide

Have feedback or a topic you'd like us to cover? Let us know here

Listen to the full episode here