Hormones influence far more than reproduction—they shape energy, mood, metabolism, sleep, and long-term health. In this episode of A Whole New Level, Dr. Anjali D’Souza joins Mike Haney to explain how women’s hormones actually work, why so many symptoms are dismissed as “normal,” and how to interpret labs in a way that reflects real physiology.

They discuss why standard hormone panels often miss functional problems, how nutrient status and lifestyle affect hormone signaling, and how symptoms like PMS, fatigue, and brain fog provide meaningful data—not noise.

They discuss:

• Why hormones affect how you feel day to day, not just fertility
• The difference between “normal” lab ranges and optimal function
• How progesterone, estrogen, and cortisol interact
• Why PMS is often a signal—not a mystery
• How nutrition, stress, and sleep influence hormone effectiveness

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠https://levels.link/wnl⁠⁠

🎙 What Dr. Anjali Dsouza & Mike Haney discuss:

[3:45] — Why hormones influence energy, mood, and vitality

[7:30] — “Normal” labs vs. how you actually feel

[11:40] — Why hormone symptoms are often dismissed

[15:05] — Hormones as a lever to move from “fine” to “amazing.”

[18:20] — Progesterone, estrogen, and the menstrual cycle

[22:10] — Why PMS isn’t random—it’s data

[27:35] — Cortisol, stress, and hormone disruption

[33:10] — Nutrient status and hormone effectiveness

[38:45] — Why labs don’t show tissue-level hormone function

[44:30] — Lifestyle changes that support hormone balance

[50:15] — Rethinking how we assess women’s hormone health

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:

Watch the conversation: https://youtu.be/MweLkjvNimo

Find us on YouTube: ⁠⁠https://youtube.com/levelshealth?sub_confirmation=1⁠⁠

⁠https://dcimedicine.com/dr-anjali-dsouza/⁠

⁠https://www.levels.com/blog/dr-anjali-dsouza-wants-to-help-women-level-up-their-health⁠

📲 Connect with Dr. Anjali Dsouza: https://www.instagram.com/anjalidsouzamd

In this episode, Dr. Jesse Mills, Director of the UCLA Men’s Clinic, joins Mike Haney to explain what’s driving that shift and what today’s data-driven approach to men’s health looks like.

He breaks down the testosterone “revolution,” what’s really happening in low-T diagnoses, and how lifestyle, sleep, and stress management can influence hormones as much as prescriptions can.

They discuss:

- How men’s health became its own medical discipline

- What testosterone really does—and how to know if it’s low

- Primary vs. secondary hypogonadism and how to tell the difference

- When testosterone replacement is appropriate (and when it’s not)

- Why younger men are now embracing prevention and optimization

And listen to Dr. Mills’ new podcast, The Male Room with Dr. Jesse Mills, wherever you get your podcasts.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠

🎙 What Dr. Jesse Mills & Mike Haney discuss:

[2:10] — How men’s health became its own field

[8:05] — The generational shift in openness

[10:40] — The difference between real medicine and ‘men’s clinics’

[12:00] — Testosterone 101

[18:45] — When low testosterone is reversible

[26:50] — Why we need ‘forensic endocrinology’

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:

Watch the conversation: https://youtu.be/Zs2CZC2GueA

Find us on YouTube: ⁠https://youtube.com/levelshealth?sub_confirmation=1⁠

📲 Connect with Dr. Jesse Mills: https://x.com/grurology?lang=en

Your annual labs can reveal far more than most people realize—if you know how to interpret them. In this episode of A Whole New Level, Dr. Rich Joseph walks through how to read basic blood work like the CBC, electrolytes, and urinalysis, and how to use those numbers as feedback loops, not pass/fail judgments.

He explains which values matter most, what trends reveal over time, and how to connect lab data to sleep, training, nutrition, and stress.

• What the Complete Blood Count (CBC) actually measures
• How to identify early signs of iron or B-vitamin deficiency
• What white blood cell patterns reveal about immunity and stress
• How electrolytes reflect cellular energy, hydration, and training load
• Why urinalysis is underrated (and how to read it quickly)
• How to use lab trends—not single snapshots—to guide health decisions

Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

🎙 What Dr. Rich Joesph & Mike Haney discuss:

[03:12] — Why basic labs still matter

[07:58] — How to read the CBC: Red blood cells, white blood cells, platelets

[18:45] — MCV and what it tells us about iron vs. B-vitamin deficiency

[24:40] — White blood cells as a window into stress and recovery

[44:10] — Electrolytes and cellular energy

[1:01:22] — Urinalysis: the overlooked lab with real value

[1:09:55] — Using labs as feedback over time

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:
Watch the conversation: https://youtu.be/cpwB4-_7o-w

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

📲 Connect with Dr. Rich Joseph on LinkedIn: https://www.linkedin.com/in/rich-joseph-md-mba-61448b33a/

Your immune system isn’t just about fighting infections—it’s a mirror of your overall metabolic health.

In this episode of A Whole New Level, Dr. Sharon Bergquist, physician and Director of Emory’s Healthy Aging and Resilient Aging Center, joins Mike Haney to unpack the science of immune resilience—how chronic inflammation, white blood cell patterns, and metabolism intertwine to shape long-term health.

Dr. Bergquist explains why inflammation isn’t always bad, how the immune system ages, and what you can do daily to build resilience.

They discuss:

• The link between metabolic dysfunction and chronic low-grade inflammation
• How white blood cell counts reveal immune status and stress levels
• Why gut and liver health are central to immune balance
• Practical habits that calm inflammation and support immune recovery
• What it really means to have a “resilient” immune system

Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

🎙 What Dr. Sharon Bergquist & Mike Haney discuss:

[3:24] — How inflammation protects—and harms—your body

[10:11] — Why immune health depends on metabolism

[17:42] — White blood cells as a window into immune function

[24:38] — How the gut and liver shape immunity

[32:27] — Why modern lifestyles fuel inflammation

[40:55] — How to measure your own inflammation

[48:33] — The science of immune aging (inflammaging)

[56:22] — Building immune resilience through daily habits

[1:03:44] — Why immune balance is better than immune ‘boosting’

[1:11:08] — The hopeful message: immunity is adaptable

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:
Watch the conversation: https://youtu.be/k1XpdFGVx1o

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

📲 Connect with Dr. Sharon Bergquist on LinkedIn: Dr. Sharon Horesh Bergquist 

Dr. Sharon Bergquist: https://drsharonbergquist.com/

If you want to improve your energy and long-term health, start by understanding how your body uses glucose.

In this episode of A Whole New Level, Dr. Benjamin Bikman, scientist and author of Why We Get Sick, joins Mike Haney to unpack the science of glucose metabolism and insulin resistance—and why blood sugar isn’t the whole story.

Dr. Bikman explains how insulin regulates energy balance, why HbA1c is only part of the picture, and how chronic high insulin can silently drive weight gain, fatigue, and metabolic disease. He also shares practical ways to lower insulin naturally through diet, exercise, and daily habits.

They discuss:

• Why insulin, not glucose, is the root of metabolic dysfunction
• What HbA1c and fasting glucose really tell you
• The early signs of insulin resistance most people miss
• How muscle tissue protects against high glucose and insulin
• Why low-carb and intermittent fasting aren’t one-size-fits-all
• Practical nutrition and movement strategies for better metabolic flexibility

Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

🎙 What Ben Bikman, PhD, & Mike Haney discuss:

[3:42] — Why glucose isn’t the full story in metabolic health

[7:58] — Insulin’s central role in energy and fat storage

[13:10] — What HbA1c actually tells you—and what it misses

[19:23] — The first signs of insulin resistance most people overlook

[25:46] — Why muscle is a “glucose sink” that protects your metabolism

[32:15] — How modern diets overload insulin, not just glucose

[39:52] — The difference between being lean and being metabolically healthy

[46:08] — Simple daily habits that lower insulin naturally

[54:41] — Why “normal” lab ranges for insulin are misleading

[1:02:17] — Practical steps to build metabolic flexibility and better energy

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:

Watch the conversation: https://youtu.be/2PROANAQkwA

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

📲 Connect:

Connect with Dr. Bikman on X: @BenBikmanPhD

Dr. Benjamin Bikman: https://benbikman.com/

Alzheimer’s and dementia aren’t just a matter of age or genetics. Increasing evidence shows that metabolic health—particularly insulin resistance—plays a key role in cognitive decline.

In this episode of A Whole New Level, neurologist and bestselling author Dr. David Perlmutter joins Mike Haney to explore the links between brain health and metabolism. They discuss the role of insulin resistance and inflammation in Alzheimer’s disease, the biomarkers that can reveal risk decades before symptoms, and how lifestyle interventions can dramatically change your trajectory.

Topics include:

• Key biomarkers for assessing brain health: fasting insulin, A1C, homocysteine
• Why targeting inflammation may matter more than targeting amyloid plaques
• The promise and limitations of GLP-1 medications for dementia and Parkinson’s
• Practical steps you can take now to protect long-term cognitive function

Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

🎙 What Dr. David Perlmutter & Mike Haney discuss:

4:12 — Why Alzheimer’s is now called “Type 3 diabetes”

9:45 — The role of inflammation in brain health

15:22 — Biomarkers that predict dementia risk decades early

22:31 — Why mainstream Alzheimer’s drugs fall short

29:17 — GLP-1s and brain health

36:44 — Lifestyle changes vs. pharmaceuticals

44:19 — Why homocysteine matters

53:02 — Sleep, circadian rhythm, and brain resilience

1:02:38 — Early warning signs you shouldn’t ignore

1:15:07 — The hopeful message

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:
Watch the conversation: https://youtu.be/MV_9nyAN1Vk

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

📲 Connect:

Dr. David Perlmutter on X: @DavidPerlmutter

David Perlmutter, MD: ⁠https://drperlmutter.com/⁠

Longevity is a hot health topic, but what factors move the needle on not only how long you live but how long you experience relatively good health? Some lab and other tests can help assess how healthy you’re aging and provide context for what lifestyle and other changes to make. Dr. Matt Kaeberlein and Mike Haney discuss the tests that help assess healthy aging, how mental health and physical health are intricately connected, which lifestyle factors might expand your health span, and where the research stands on various longevity topics.

Get a Free Guide to Understanding Your Lab Results: https://levels.link/wnl

🎙 What Matt Kaeberlein, PhD, & Mike Haney discuss:

6:57 — Lifespan vs. health span vs. sick span

19:38 — Understanding sick span

27:44 — Biomarkers and other tests to assess health span

30:58 — The importance of emotional health for longevity

35:49 — Cellular tests may not have value for the consumer yet

42:24 — On mitochondrial function and telomere length

50:34 — Investing in your health

1:01:18 — Lifestyle changes can help make a big difference

1:09:50 — High vs. low protein

1:16:39 — When considering exercise, building muscle is crucial for longevity

1:27:37 — The prescription drug rapamycin is not FDA-approved for longevity

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:

Watch the conversation: https://youtu.be/OPH5Nb2a69o

Subscribe here on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

Matt Kaeberlein, PhD: https://www.optispan.life/matt-kaeberlein

Connect with Matt Kaeberlein, PhD, on X: https://x.com/mkaeberlein

Your thyroid test results explained: The thyroid is a butterfly-shaped gland in your neck that affects many facets of health. When it doesn’t function optimally, symptoms can ensue. That’s where testing comes in, but the results can be tricky to interpret (and treat if necessary) without a knowledgeable clinician. Dr. Angela Mazza and Mike Haney discuss thyroid function, thyroid hormone and related tests and what they mean, treatment for thyroid conditions, the benefits of an integrative approach to thyroid care, and more.

Get a Free Guide to Understanding Your Lab Results: https://levels.link/wnl

🎙 What Angela Mazza, DO, & Mike Haney discuss:

2:44 — What is endocrinology?

4:31 — What does the thyroid do?

6:33 — Understanding hyperthyroidism

10:08 — The “triangle” of autoimmune disease

13:56 — Understanding hypothyroidism

16:29 — Thyroid-stimulating hormone

21:43 — Considering reverse T3

27:11 — Thyroid ultrasound

37:32 – The importance of individualized thyroid replacement therapy

40:53 — The thyroid gland and perimenopause

42:49 — Misinformation about the thyroid

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:

Watch the conversation: https://youtu.be/HRNKRniVALk

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

Angela Mazza, DO: https://www.metaboliccenterforwellness.com/

Metabolic Center for Wellness: https://www.metaboliccenterforwellness.com/

“Thyroid Talk: An Integrative Guide to Optimal Thyroid Health”: https://www.amazon.com/Thyroid-Talk-Integrative-Optimal-Health/

Thyroid Talk community and training: https://www.thrivethyroid.com/

Thyroid Talk podcast: https://www.metaboliccenterforwellness.com/copy-of-protocols-1

Connect with Angela Mazza, DO, on Instagram: https:// https://www.instagram.com/metaboliccenterforwellness/

Greater accessibility to glucose biosensors has led to their use to improve metabolic health, prevent disease, and feel better. Historically, these biosensors for monitoring glucose were only available with a prescription, often reserved for people with diabetes, but now with brands like Stelo, they are available over the counter. Dom D’Agostino, PhD, and Ben Grynol discuss how biosensors can be a tool for anyone to improve overall health, reduce risk for chronic diseases, manage women’s health including menstrual cycles and the menopause transition, help with fueling strategies for workouts and performance, prevent energy crashes, and more.

Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

🎙 What Dom D’Agostino, PhD, & Ben Grynol discuss:

11:49 — Using technology to reduce your risk for health issues

14:13 — Metabolic health is a spectrum, and many people don’t know where they stand

25:25 — The importance of focusing on trends in your metabolic health

30:05 —  Glucose spikes from workouts are normal and a good sign

34:13 — Glucose is one of the key biomarkers to track for longevity

41:34 — Understanding what a glucose biosensor is

56:17 — All calories are not created equal

1:01:25 — Using a glucose biosensor for exercise fueling strategies

1:04:00 — Using a glucose biosensor to monitor women’s health changes

1:23:11 — The rate of glucose absorption matters for metabolic health and how you feel

1:31:06 — Making healthy food the default, rather than ultra-processed foods

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:
Watch the conversation: https://youtu.be/mrlnNhxKNgY

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

Dominic D’Agostino, PhD: https://drdominicdagostino.com/

Dominic D’Agostino, PhD, on X: https://x.com/DominicDAgosti2

Our kidneys filter out waste while retaining substances the body needs, such as electrolytes. Kidney health, which can be assessed with blood and urine biomarker tests, is paramount to overall health. Yet lifestyle, such as the Western diet and other factors, can damage the kidneys, leading to either a slow progression of issues or acute injury. Dr. Rick Johnson and Mike Haney discuss the role of the kidneys, what lifestyle factors affect kidney health, ways to support the kidneys, and what your biomarker results tell you about the function of these crucial organs.

Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

🎙 What Rick Johnson, MD, & Mike Haney discuss:

4:26 — Your kidneys are great regulators

8:43 — Heat stress affects the kidneys

12:04 — The most common causes of kidney disease include diabetes and high blood pressure

19:46 — The Western diet is associated with age-related kidney decline 

32:25 — The concerns of a high-protein diet in the presence of chronic kidney disease

41:15 — Changes in urinary habits or color could indicate chronic kidney disease

46:23 — Biomarkers can help assess kidney function

53:18 — Serum creatinine as a biomarker of kidney health

1:08:13 — Assessing patterns over time is crucial

1:10:52 — High albumin in the urine is a sign of kidney disease

1:21:26 — Lifestyle changes that support kidney health

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:
Watch the conversation: https://youtu.be/8_QSuYwo5wg

Subscribe here on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

Richard Johnson, MD: https://drrichardjohnson.com

Comprehensive Clinical Nephrology: https://drrichardjohnson.com/books/

Connect with Richard Johnson, MD on Instagram: https://www.instagram.com/drrichardjjohnson/

Your gut microbiome affects everything from your mental health and cognitive function to your immune system and metabolic health. Gut health symptoms, such as bloating, gas, constipation, or diarrhea, could be a sign that you have low species diversity. Dr. Will Bulsiewicz and Mike Haney discuss how the gut and brain communicate, how the gut microbiome affects the gut barrier and therefore your immune system, what to eat to improve the gut microbiome, and what microbiome testing can tell you.

Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

🎙 What Will Bulsiewicz, MD, & Mike Haney discuss:

9:14 — Gut health takes time to improve

14:49 — Your gut microbiome informs your gut and overall health

18:42 — Lifestyle choices help shape an individual’s gut microbiome

24:20 — A compromised gut barrier affects the immune system

30:51 — Nutritional strategies can improve the gut microbiome and reduce disease flares 

32:46 — The gut and the brain communicate

52:27 — A diverse gut microbiome is a sign of good health

56:45 — Your gut microbiome informs your bowel movements

1:01:46 — When to see a doctor for gastrointestinal symptoms

1:05:32 — Increasing fiber helps the gut microbiome

1:11:41 — The beneficial byproducts of gut microbes are postbiotics

1:14:59 — Eat a wide variety of plant foods to get optimal fiber

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:
Watch the conversation: https://youtu.be/iAHOycufGn8

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

Will Bulsieweicz, MD, https://theplantfedgut.com/about/

Fiber Fueled: https://www.amazon.com/Fiber-Fueled-Plant-Based-Optimizing-Microbiome/dp/059308456X

The Plant Fed Gut: https://theplantfedgut.com/

Connect with Dr. Will Bulsiewicz on Instagram: https://www.instagram.com/theguthealthmd/?hl=en