Fernando Tortosa and Ariel Izcovich discuss various aspects of hantavirus infections with a focus on the situation in Argentina, including transmission, epidemiology, clinical course, management, latest research developments, difficulties in conducting clinical trials, and future research priorities. The speakers also discuss the main findings and clinical implications of a study 'Use of tocilizumab for severe hantavirus pulmonary syndrome: a MEURI case series with contextual comparisons' they recently published in the journal.

Click here to read the full article:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00285-9/abstract

The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

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Dr Brecht Ingelbeen and Dr Daniel Valia join Senior Editor Phoebe Hall to discuss a new trial in the journal (the CABU-EICO trial) testing a co-created behavioural intervention bundle to improve antibiotic use, patient management, and water, sanitation and hygiene in rural communities in Burkina Faso and DR Congo.
They explain why the study focused on community prescribing (not hospitals), the primary endpoint was a reduction in WHO AWaRE Watch antibiotics (not overall antibiotics), and the intervention targeted all providers of antibiotics in the community, including informal vendors.

Finally, they discuss the importance of designing an intervention bundle that was truly tailored to local context yet practical, sustainable, and scalable beyond the study sites. A parallel study reporting the effect of the intervention bundle on ESBL-producing Escherichia coli colonisation (a co-primary outcome of the trial) is in press at The Lancet Microbe.  

To read the full article:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00169-6/fulltext

The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

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Sara Tartof and Matan Yechezkel discuss a new article in The Lancet Infectious Diseases about emerging doxycycline resistance against gonorrhoea and its wider implications for the implementation of doxycycline and the prevention of bacterial sexually transmitted infections.

Click here to read the full article:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00123-4/fulltext

The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

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Dr Jenny Clarke and Herve Semukunzi discuss a study they and colleagues recently published with us  titled ‘Infection- and vaccine-induced mpox antibodies: validation of a combined mpox IgG ELISA during the clade 1b outbreak in Rwanda’. 

They also discuss the reasons for the paucity of validated serological assays for mpox, particularly in outbreak regions where they are most urgently needed. 

Click here to read the full article: 

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(26)00006-X/fulltext

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The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

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Dr Julia Moore Vogel and Dr Danilo Buonsenso discuss various aspects of long COVID including epidemiology, pathophysiology, underlying mechanisms, management, latest research developments, difficulties in conducting clinical trials, and future research priorities.

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The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

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Professors Steven Tong and Joshua Davis discuss all aspects of adaptive platform trials including advantages, disadvantages, differences from conventional trials, and tips for setting up and assessing them.

They also highlight several adaptive platform trials currently in the pipeline that could influence infectious disease clinical practise in the future.

Click here to read our latest issue

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The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

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Professor Ana Odone, Dr Jesus Rodriguez-Manzano, and Dr Alex Howard discuss their new Series of papers on artificial intelligence and infectious diseases intended to support the infectious diseases community in understanding this evolving landscape and in actively shaping artificial intelligence integration into practice.

Read the full Series here:

https://www.thelancet.com/series-do/artificial-intelligence-and-infectious-diseases?dgcid=buzzsprout_icw_podcast_laninfaiandid25_laninf

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The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

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Drs Catherine Liu and Joshua Hill of the Fred Hutchinson Cancer Center discuss their new Series of papers on the prevention and management of infections in people who are immunocompromised, with a focus on prevention of infections and diagnostic and antimicrobial stewardship.

Read the Series papers:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00345-7/fulltext?dgcid=buzzsprout_icw_podcast_August_25_laninf

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00311-1/fulltext?dgcid=buzzsprout_icw_podcast_August_25_laninf

Read the linked Comment:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00355-X/fulltext?dgcid=buzzsprout_icw_podcast_August_25_laninf

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The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

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Lilian Tina Minja and Norbert Heinrich discuss the SUDUCO and DECODE trials in The Lancet Infectious Diseases on two new promising TB drugs, sutezolid and delpazolid, respectively. They also discuss the wider implications of the findings of these trials for TB drug development and treatment.

Read the trials:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00213-0/fulltext?dgcid=buzzsprout_icw_podcast_July_25_laninf

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00289-0/fulltext?dgcid=buzzsprout_icw_podcast_July_25_laninf

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The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

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Leonardo Basso and Juan Pablo Torres discuss their study in The Lancet Infectious Diseases on the effectiveness and impact of the first season of Chile's national immunisation programme with nirsevimab. They discuss the evidence that led to the design and implementation of the programme, its impact on RSV burden and the Chilean health system, and lessons for other countries in the region and beyond.

Read the full article at: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00233-6/fulltext?dgcid=buzzsprout_icw_podcast_10-06-25_laninf

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The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

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Jan Felix Drexler and Fernando Bozza discuss their recent study published in the journal— “The spatio-temporal ecology of Oropouche virus: a laboratory-based modelling study across Latin America” and its wider implications for Oropouche virus and other arboviruses transmission, expansion, surveillance, and control.

Read the full article:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(25)00110-0/fulltext?dgcid=buzzsprout_icw_podcast_14-04-25_laninf

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The Lancet Infectious Diseases in conversation with...  is part of the Lancet Group podcast offering. 

Editorial team: editor-in-chief Ursula Hofer, deputy editor Marco De Ambrogi, and senior editors Syeda Saleha Hassan and Phoebe Hall

Podcast editing: Matteo Simonetti

Visit https://www.thelancet.com/multimedia to learn more about our multimedia offering. 

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