In today’s episode, Dr. Kent Holtorff and I cover an array of topics from the incredible potential of bioregulators in reversing aging and optimizing health, to innovative therapeutic strategies for complex health issues like hypothyroidism and chronic kidney disease. Dr. Holtorff shares some fascinating insights from his clinical practice, including his pioneering work with veterans suffering from PTSD and traumatic brain injury, where bioregulators and peptides have shown remarkable therapeutic benefits.

You can also find a lot of the products we discuss in this episode at Integrativepeptides.com and as a listener of this podcast you get to use code NAT10 to save on anything in the store!

What We discuss:

Dr. Kent Holtorff Background and Expertise ... 00:08:45

The Beginning of Peptide Interest ... 00:11:02

Early Use of Bioregulators in Germany ... 00:12:15

Transition from Peptides to Bioregulators ... 00:18:34

Relating Epithalamin and Epitalon ... 00:20:00

Introduction to New Bioregulators ... 00:23:17

Insight from Russian Literature ... 00:27:10

Thyroid Bioregulator Development ... 00:35:00

Our Amazing Sponsors:

Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order! 

SiPhox - SiPhox is the only comprehensive at-home blood testing solution that lets you check up to 50 biomarkers from your home. No travel, no appointments, just a few drops of blood on a card and you're set. You'll get easy to understand insights and a clear plan of action to help optimize your health, all based on your unique results. Visit SiPhoxhealth.com forward slash nat and you get 20 % off your first order using code NAT.

Just Thrive - 99% of probiotics on the market die in your stomach before they even reach your gut. Just Thrive is the only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90 day bottle.

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Today’s guest is Dr. Michael Ruscio, a renowned naturopathic practitioner, who discusses the critical links between gut health, brain health, and overall well-being. They discuss new insights into IBS, revealing its reclassification as a gut-brain interaction disorder, and dive into different dietary strategies for managing gut issues, including low FODMAP, Candida, and low histamine diets.

Dr. Ruscio offers expert advice on navigating common health concerns like gluten sensitivity, nutrient intake, and the effects of modern life on gut health. He emphasizes a step-wise, holistic approach to healing, underscoring the body's natural ability to restore balance.

Tune in for practical insights on improving gut health and enhancing longevity through balanced nutrition and thoughtful dietary choices.

Exciting Announcements!

This podcast can count for continuing education for nurses check out RNEGADE Pro for more info!

Biohacker Expo - I’ll be speaking on the main stage at the Biohacker Expo in FL this month. Visit biohackerexpo.com and use code NAT50 for 50% off your ticket! I’ll see you there on Friday, Feb 28 on the MainStage at 11 am.

What We discuss:

Functional Gastrointestinal Disorders (FGDS) ... 00:10:02

Gut and Mental Health Connection ... 00:11:00

Different Gut Types and Diets ... 00:12:45

Personalizing Diets for Gut Health ... 00:15:31

Hormones and Thyroid Issues ... 00:30:00

Red Light Therapy for Thyroid Health ... 00:39:00

The Role of Gluten in Gut Health ... 00:45:32

Impact of Location on Gluten Sensitivity ... 00:50:32

BPC-157 and Peptides in Gut Health ... 01:07:32

Seed Oils and Omega Balances ... 01:03:24

Podcast Wrap Up and Where to Find Dr. Ruscio ... 01:10:21

Our Amazing Sponsors:

LVLUP CREvolution - The secret to CREvolution? It’s all about GAA. This powerful compound helps you get more creatine into your cells and faster than traditional creatine. Combine that with the absorption power of HBCD, and you’ve got a formula that’s built for serious results. Head to lvluphealth.com and use the code NAT for 15% off.

JJ Virgin -  Listen to Well Beyond 40 If you're ready to take control of your health and feel your best at any age, head to followjjvirgin.com

Timeline - Improve your cellular energy, strengthen muscle, and boost endurance by taking Mitopure daily. Mitopure unlocks 6x more Urolithin A than diet alone. Use code NAT10 for 10% off your order at timelinenutrition.com.

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Today we’re lifting the lid on the food industry’s best-kept secrets with Jeffrey Smith. Ever wonder why gut issues, anxiety, or even insomnia are on the rise? It turns out, that GMOs and glyphosate—the chemical found in everything from cereal to wine—might have something to do with it. 

Jeffrey Smith is the Founder & Executive Director of the Institute for Responsible Technology, a Best Selling Author Seeds Of Deception, and a Filmmaker.

He reveals the jaw-dropping results of a study where thousands of people saw improvements in 28 conditions after switching to organic. Stick around to learn why glyphosate has been called a "Darth Vader chemical" and why your pantry might be plotting against you.

Resources:

Glyphosate Report

Non-GMO Shopping Guide…And When You Dine Out

What I Discuss:

NeuralRx Advertisement ... 00:01:59

Discussion on GMOs and glyphosate ... 00:06:17

The rise of certain diseases and their correlation with GMOs and glyphosate ... 00:26:43

BT toxin explanation and its risks ... 00:43:22

Impact of glyphosate on gut health and mineral absorption ... 00:53:30

Second advertisement: Youth Daily by Young Goose ... 00:49:18

Healing prospects with an organic diet ... 00:56:17

Dangers of gene editing (GMO 2.0) ... 01:03:32

Urgent need for regulatory action and support for IRT ... 01:16:01

Sponsors:

Wizard Sciences (Neural Rx) - Neural Rx isn’t just about a quick boost. It’s designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.

Young Goose (Youth Daily) - Youth Daily activates your skin's anti-aging genes, shields against environmental nasties by day and tackles signs of aging by night. Visit Younggoose.com and use code NAT20 on your first order, or, if you’re an existing customer 5NAT will reward you with an ongoing discount.

SiPhox - The only comprehensive at-home blood testing solution that lets you check up to 50 biomarkers from your very own home. No travel, no appointments, just a few drops of blood on a card and you're set. Visit SiPhoxhealth.com/nat and you get 20 % off your first order using code NAT. 

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In this episode, I discuss the fascinating and multi-faceted practice of fasting. Today I uncover the various types of fasting—from intermittent fasting and water fasting to the more intensive dry fasting and the innovative Fasting Mimicking Diet.

*More about the Fasting Mimicking Kit at prolonlife.com/Nat for 20% off (applied at checkout). If you’re in Canada you can just go to Prolonfast.ca and use code NAT20 to save.

What I Discuss:

Types of Fasting Explained ... 01:15

Intermittent Fasting and Eating Windows ... 02:45

Skipping Breakfast vs. Skipping Dinner ... 04:10

Different Intermittent Fasting Schedules (16/8, 18/6, 20/4) ... 06:05

Benefits of Longer Fast Durations ... 09:30

Water Fasting and Its Effects ... 10:45

Dry Fasting: Risks and Rewards ... 12:20

Alternate Day Fasting Overview ... 14:50

Protein Sparing Modified Fasts ... 17:15

Introduction to Bone Broth Fasting ... 19:00

Fasting Mimicking Diet Explained ... 21:40

Significance of Nutrient Density and Sleep ... 24:25

Enhancing Fasting with Peptides, Bioregulators, and GLP1s ... 26:10

Consulting Medical Providers Before Fasting ... 28:50

Made Possible By Our Amazing Sponsor:

BiOptimizers: It’s the only full-spectrum magnesium supplement with 7 unique forms of magnesium that your body can actually use and absorb. Go to  bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order.

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In this episode, I’m joined by the incredible Dr. Jeff Gross from ReCELLebrate, a top neurosurgeon specializing in non-surgical regenerative medicine. Dr. Gross is here to debunk some long-standing myths, most notably the belief that cartilage can't regrow. 

What We Discuss:

Introduction to regenerative medicine and stem cells ... 00:50

Stem cell differentiation and their potential ... 03:45

Patient preparation before therapies ... 06:20

Exosomes and their therapeutic benefits ... 09:05

Applications in joint and sports injuries ... 12:30

Treating osteoarthritis and cartilage regeneration ... 16:10

Bone edge vs. joint injections for osteoarthritis ... 19:15

Legalities and misconceptions about stem cell therapies ... 28:30

Safety with stem cell treatments ... 31:45

PRP, adipose products, and amniotic fluid in therapies ... 34:15

Dr. Gross’s professional journey in regenerative medicine ... 37:35

Dr. Gross’s contact information for consultations ... 42:20

Final thoughts and future advancements ... 45:00

Made Possible By Our Amazing Sponsor:

Puori - Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order.

BEAM Minerals - Their Liquid Formula delivers the perfect mix of all these sleep supporting minerals. Visit beamminerals.com and use code NAT20 to get 20% off your order.

Young Goose - Get 10% off your first order with code NAT10 and this link. And save on future orders with code 5NAT using this link.

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In this episode, Renee Fitton from Prolon Life joins me in a discussion about how to gain all the benefits of fasting without feeling hungry and giving up!

Learn more about Renee Fitton and her Fasting Mimicking Kit at prolonlife.com/Nat, where podcast listeners get 20% off at checkout! In Canada? Visit Prolonfast.ca and use code NAT20 to save.

What We Discuss:

Nathalie's new health initiative announcement ... 00:45

Encouragement to start fasting anytime ... 02:00

Invitation to join the group fast, March 2nd ... 05:00

Caffeinated beverages and fasting ... 07:15

Contents of ProLon five-day fast ... 08:45

L drink benefits and tips ... 09:30

Fasting recommendations ... 10:15

Muscle-sparing properties of FMD ... 12:30

Dr. Longo's research findings ... 13:15

Recommendation to start with three FMD cycles ... 14:00

FMD's benefits in oncology ... 14:45

Combining GLP-1s with FMD ... 20:00

Intermittent fasting and circadian rhythms ... 21:45

Nat’s experience with ketosis ... 32:15

Bio-individuality in fasting responses ... 33:00

Safety of fasting mimicking diets ... 35:15

Made Possible By Our Amazing Sponsors:

Mitopure from Timeline: Improve your cellular health by taking Mitopure in its simplest form with two vegan softgels daily for the recommended dose of Urolithin A (500mg of Mitopure). Visit timeline.com/nat10 for 10% off.

SOLTEC: Struggling with restless nights and daily stress? Introducing the Soltec System—a revolutionary solution designed to transform the way you sleep and manage stress. Visit www.soltechealth.com for $100 off your purchase using code LONGEVITY. Experience the difference for yourself with a 60-day risk free trial.

LVLUP: The secret to CREvolution? It’s all about GAA. This powerful compound helps you get more creatine into your cells faster than traditional creatine. Ready to crush your next workout? Head to lvluphealth.com and use the code NAT for 15% off.

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Today, we dive into a thought-provoking discussion with Dr. Jennifer Simmons, a breast cancer surgeon turned functional medicine oncologist, who is redefining breast cancer diagnosis, treatment, and screening.

Use Jenn's code: Drjenn20 for 20% of the Auria test.

What We Discuss:

Critique of Mammograms and Below-Average Efficacy ... 03:15

Canadian Breast Cancer Screening Trial Findings ... 06:50

Concerns with Overdiagnosis in Mammograms ... 08:25

Consequences of Unnecessary Breast Cancer Treatments ... 11:40

Absence of Predictive Tests for Cancer Aggressiveness ... 15:10

Debunking the Myth of Early Detection's Efficacy ... 18:00

Dense Breast Tissue and Mammogram Limitations ... 21:30

Risks Associated with Mammogram Radiation ... 24:10

Importance of Lymphatic System Health ... 29:00

Alternative Approaches to Monitoring Breast Health ... 32:20

Holistic Benefits of Rebounding, Dry Skin Brushing ... 35:45

Criticism of Restrictive Bras and Advice on Usage ... 38:10

Bioidentical Hormone Replacement Therapy (HRT) Insights ... 41:20

Misconceptions About Estrogen and Breast Cancer ... 45:05

Introduction to the Mitolux Device ... 51:50

Dietary and Physical Recommendations for Optimal Health ... 54:20

History and Long-term Impact of Breast Health ... 1:09:05

Pharmaceutical Dependencies and Lifestyle Impact ... 1:12:20

Arguments Against Over-treatment of DCIS ... 1:15:30

Innovative Breast Cancer Screening Tests: AURIA and QT Scan ... 1:18:50

Challenges with Current Breast Cancer Treatments ... 1:22:10

Ethical Considerations in Breast Cancer Treatment ... 1:25:45

Made Possible By Our Amazing Sponsor:

SiPhox - SiPhox Health offers at-home blood testing solutions, providing custom supplements based on your personalized blood work. Visit http://SiPhoxhealth.com/nat and use code LONGEVITY to save on your test.

Manukora - Looking to boost your immunity and gut health with nature's finest? Manukora Honey, sourced from New Zealand, brings you high-quality honey rich in health benefits. Visit this link http://manukora.pxf.io/kO0rJN to enjoy a special discount with the code LONGEVITY.

Wizard Sciences - Ready to upgrade your brain game? Unlock your cognitive potential with Neural Rx. Use code NAT15 at checkout to get 15% off your purchase. Don’t wait—start the year with a sharper, more focused mind. Visit Wizardsciences.com

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In today's episode, I reveal the top health trends of 2025 that you can't afford to miss.

What We Discuss:

2025 Trends in Health ... 01:15

GLP1s: Managing body composition with emerging variations ... 01:30

Importance of lifestyle factors such as diet and exercise alongside GLP1s ... 03:45

Home Testing Innovations ... 05:05

Theriom’s Aristotle Test and upcoming microbiome test ... 05:25

MI Screen: Non-invasive mitochondrial function test ... 07:40

True Diagnostic: The Harmony Test for aging ... 09:00

Syphox: Comprehensive blood analysis innovation ... 10:45

Vaitrakt: Affordable gut microbiome test ... 11:35

Prodrome Science Test: Practitioner guided health insights ... 13:20

Early Cancer Detection Advances ... 15:00

Auria Test: Tear-based breast cancer detection ... 16:50

QT Scan: Imaging dense breasts non-invasively ... 18:35

Cardiovision Care: Predictive cardiovascular disease test ... 20:10

Emerging Technologies in Peptides and Bioregulators ... 21:45

Enhanced bioavailability through skin delivery ... 22:00

Addressing past traumas and experiences for holistic health ... 27:25

Closing Remarks and Teasers for Future Episodes ... 31:30

Made Possible By Our Amazing Sponsor:

Mitopure from Timeline: Improve your cellular health by taking Mitopure in its simplest form with two vegan softgels daily for the recommended dose of Urolithin A (500mg of Mitopure). Visit timeline.com/nat10 for 10% off. That's timeline.com/nat10.

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Today’s guest, Jean Fallacara, is part scientist, part philosopher, and 100% here to help us rethink mornings, aging, and what it means to truly live well.

What We Discuss:

Biohacking challenges: optimizing versus expensive elite pursuit ... 09:26

Lifestyle shift is about sustainable, basic habits ... 13:56

Embrace natural lifestyle over modern "biohacking" ... 17:17

Calm mornings improved her busy, chaotic life ... 24:51

Morning meditation, mindfulness, present focus, no projections ... 28:39

Be the pilot of your own life ... 35:09

Age-defying calisthenics through mind-body connection ... 39:56

Gut health impacts resolutions; probiotics enhance success ... 45:56

Adjusting age impacts health, but basics remain ... 54:37

Fasting activates autophagy, aiding natural fat loss ... 59:08

Fasting weekly now, lost weight too fast ... 01:01:41

Prioritizing sleep improves well-being despite noise ... 01:06:45

Challenged, not sore; testing improved suit technology ... 01:12:03

AI impacts research, urges responsibility for future ... 01:20:05

AI-powered platform offers personalized supplement recommendations ... 01:22:44

Made Possible By Our Amazing Sponsors:

Zona Health - A small, handheld device that you squeeze using the science of isometric exercise. In just a few minutes a day, it can naturally boost blood flow, reduce stress, and lower your blood pressure. Visit zona.com, and use code NAT24 to save $100 on your Zona Plus.

Puori - Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order. Or, if you want to go big and get nearly a third off with a subscription, you can do that too. Head to Puori.com/NAT and use promo code NAT at checkout.

Just Thrive - The only probiotic guaranteed to arrive 100% alive where you need it most. Visit JustThriveHealth.com and use code NAT20 for 20% off your first 90 day bottle

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Are you tired of yo-yo dieting and struggling to achieve lasting weight loss? Have you heard about the buzz surrounding GLP-1 agonist medications like semaglutide and tirzepatide but aren't sure how to effectively incorporate them into your journey? 

In today’s episode, Dr. Gus Vickery and I discuss the effective use of GLP-1 agonist medications like semaglutide and tirzepatide for sustainable weight loss. He emphasizes the need for a mindset shift, viewing these drugs as powerful tools to catalyze positive changes rather than easy fixes or crutches. Dr. Vickery explains that these medications provide leverage to implement foundational healthy habits and that the key to success lies in focusing on nutrient sufficiency, not just calorie restriction.

We also discuss concerns surrounding GLP-1 medications, such as the potential for muscle loss and the risk of regaining weight after discontinuing the drugs. He shares strategies to mitigate these issues, including resistance training, adequate protein intake, and gradual dose reduction when nearing one's goal weight.

Dr. Gus Vickery is an author, speaker, and the founder and directing physician of Authentic Health in Asheville, North Carolina. He established his practice with a commitment to delivering holistic, compassionate, and evidence-based care.

Thank you to our sponsors for making this episode possible:

BiOptimizers: BiOptimizers: Go to bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order.

What We Discuss: 

04:00 Understanding the Power of Peptides

07:45 The Underlying Benefits of Peptides

12:59 Addressing Concerns about Side Effects

29:06 The Right Way to Use Peptides

30:06 Hormone Therapy and Peptides

34:12 Nutrient Sufficiency and Protein

41:17 The Impact of Fasting and Gut Health

45:33 Addressing Microbiome Balance

58:56 The Pace of Fat Loss and Patience

59:42 Pushing Through Plateaus and Delicate Nervous System

01:07:13 Managing Hormetic Stress and Resting the Nervous System

01:09:00 Choosing Carbs or Fats and Individualization

Key Takeaways:

• Peptides can be a powerful tool for improving body composition and metabolic health.

• It is important to understand the proper use of peptides and not rely on them as a quick fix or easy way out.

• Peptides have a range of benefits, including improving insulin sensitivity and reducing fatty liver disease.

• Concerns about side effects and risks should be weighed against the potential benefits and individual circumstances

Find more from Dr. Gus Vickery: 

Website: https://drgusvickery.com/ 

Authentic Health Book: https://drgusvickery.com/book/ 

Instagram: @drgusvickerymd 

Youtube: The Family Doctor

Find more from Nathalie:

YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 

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Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 

We've reached that glorious time of year when we wrap up, reflect, and maybe indulge in a few too many holiday treats. In this final solo episode of 2024, we’re counting down our greatest hits and giving you the scoop on what’s been buzzing in the world of health and longevity. We're nearly at 2.5 million downloads—can you believe it? And we're gearing up for our epic 300th episode. Time flies when you're finding ways to live longer!

Today, I’m diving into the hot debates over GLP1 agonists like Ozempic and Mounjaro. Love them or hate them, they’ve been the talk of the town this year. I’ll share why I’m team GLP1 (with a few pro tips, of course) and how you can maximize their benefits without turning into a couch potato.

We’ll also revisit some fan-favorite topics like creatine for more than just bulking up, the magical digestive powers of Tudka, and why everyone’s talking about their mitochondria like they’re tiny power plants. Oh, and let’s not forget my new love affair with the Soltek system—a game-changer for better sleep that’s been knocking my socks off!

So, grab your favorite drink (matcha latte, anyone?), get comfy, and let’s countdown the biggest hits of 2024. Thank you for sticking with us, for downloading, commenting, and just being your fabulous selves. Here’s to health, happiness, and a wildly exciting new year!

Thank you to our sponsors for making this episode possible:

SOLTEC - Struggling with restless nights and daily stress? Introducing the Soltec System—a revolutionary solution designed to transform the way you sleep and manage stress. Visit www.soltechealth.com to learn more and save $100 off your purchase using the code LONGEVITY. Experience the difference for yourself with a 60-day risk free trial.

Products Mentioned:

Paleovalley - https://www.paleovalley.com/?pc=pvpartners&oid=26&affid=1478  

Kion - https://www.getkion.com/nat

LVLUP Health - https://lvluphealth.com/?ref=nat Code NAT20

BodyBio - BodyBio.com/discount/NAT15  Code NAT15

Kineon - https://kineon.io/?oid=1&affid=45  Code NATNIDDAM

uBlockout - https://www.ublockout.com/ultimate-blackout-shade.html?affiliate=NAT10 Code NAT10

Jaspr - https://jaspr.co/products/jaspr-pro?rfsn=7868037.0592817  Code NAT

Soltec Health - http://soltechealth.com/Longevity  

Other Links:

Designs for Health - https://www.designsforhealth.com

Plus Factor - https://www.amazon.com/Plus-Factor-Cellular-Boost-Complex/dp/B0C4FS7D95

Urolithin A Episode - https://tinyurl.com/3xzzhkbu 

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What I Discuss:

01:15 What’s been said about GLP-1 Agonists in 2024 

03:11 3 strategies for using GLP-1

08:36 Microdosing GLP-1 

10:12 Hot topics in 2024 Tudka and Creatine 

14:33 The only way to measure mitochondrial function

20:19 Boomer Anderson  (254) episode was great, go back and listen

23:22 How sleep affects Mitochondrial function