Science is Fun!

Peter Turnbaugh

  • 1 hour 46 minutes
    How genes get turned off
    Today I'm joined by another floor-mate of mine at UCSF, Bassem Al-Sady. Bassem's lab does beautiful and elegant work on how genes are silenced in cells ranging from yeast to stem cells. He explains all the mysteries that remain about this fundamental process and that aspects of it date back to the earliest types of cells. We also talk about his innovative teaching efforts and how to improve graduate education.
    17 March 2024, 5:00 am
  • 1 hour 37 minutes
    What boxing teaches us about autoimmunity
    This week I'm so thrilled to interview Dr. Stephen Hauser, author of "The Face Laughs While the Brain Cries." He discusses a remarkable career as a physician-scientist, in which he uncovered a key role for B cells in the debilitating autoimmune disease multiple sclerosis. More remarkably, his perseverance led to the transformative drugs that are now available for this disease, emphasizing the importance of basic science for addressing long-standing healthcare challenges and the unique lens that practicing physicians can bring to biomedical research.
    3 March 2024, 5:00 am
  • 1 hour 47 minutes
    Can we eat saturated fat again?
    This week I'm so thrilled to interview Dr. Ron Krauss. Ron has make seminal contributions to our understanding of heart disease, including early work on cholesterol and his ongoing studies of statins. He explains why human nutrition is so hard and what is needed to provide more predictive dietary guidelines.
    18 February 2024, 5:00 am
  • 1 hour 40 minutes
    Synbio meets immunotherapy
    Synthetic biologist Kole Roybal joins us today. Kole is a leader in the emerging area of cell therapy, and has developed sophisticated ways of controlling immune cells for the treatment of cancer. He explains what led to these very recent breakthroughs and what he's excited about next.
    4 February 2024, 5:00 am
  • 1 hour 7 minutes
    Finding the AIDS virus
    This week I'm joined by Jay Levy, a world expert in HIV. Jay was one of the first people to isolate the virus and had made numerous contributions to our understanding of HIV and AIDS. He walks us through this fascinating history and the current challenges in this area.
    21 January 2024, 5:00 am
  • 1 hour 24 minutes
    Natural born killers
    I'm thrilled to interview Lewis Lanier this week, who recently stepped down as my department chair. Lewis has had a remarkable career in science and industry, including the early days of flow cytometry and the discovery of a new type of immune cell dubbed the "natural killer cell". He explains how these NK cells were found and why they're so unique and fascinating.
    7 January 2024, 5:00 am
  • 1 hour 7 minutes
    Placentas are amazing
    This week my guest is Dr. Susan Fisher, a world renowned expert in the placenta. She explains how truly remarkable the placenta is and how it overturns a lot of what we normally assume about the body.
    17 December 2023, 5:00 am
  • 1 hour 21 minutes
    The bacterial cell whisperer
    I'm am so excited to welcome Dr. Shaeri Mukherjee to the show. Shaeri is my next-door neighbor at UCSF and has been dubbed the "bacteria whisperer". Her lab uses bacteria as tools to uncover fundamental insights into cell biology.
    3 December 2023, 5:00 am
  • 1 hour 31 minutes
    Filming a movie using CRISPR technology

    We’re back this week with Seth Shipman from the Gladstone Institutes and the University of California, San Francisco. Seth has built molecular recording devices that can record data within living cells. He even used these methods to re-create one of the first movies put to film. This work has clear technological implications and is also providing insights into phage biology.

    10 February 2023, 11:00 am
  • 1 hour 53 minutes
    Who needs a biochemist when you have tiny beads?

    We’re back this week with Polly Fordyce. Polly is an Assistant Professor of Genetics and Bioengineering at Stanford. She has built remarkable tools for studying transcription factors and enzymes, really accelerating what is possible and opening up new areas of study. She explains why hydrogels are so cool and how you too can use them in your research program.

    27 January 2023, 11:00 am
  • 1 hour 49 minutes
    Fruit flies love the metaverse

    Science is Fun is finally back after a long hiatus. Where have we been? I’ve been doing science now that the pandemic slow-down has lifted. So much science to do, so little time! I’ve got an exciting line-up for the next few weeks - a mini-season of shows. I hope you enjoy it and stay subscribed to the show for when our next full season launches. This week I welcome Dr. Yvette Fisher to the show. Yvette is a neuroscientist at the University of California, Berkeley. She does wild experiments, including putting fruit flies into virtual reality simulations to study how their brains work. I hope you’ll enjoy our chat as much as I did!

    13 January 2023, 11:00 am
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