In this episode of The Defiant podcast we speak with Morgan Krupetsky, VP of OnChain Finance at Ava Labs, to break down one of the most significant shifts happening in crypto today: the rapid institutionalization of blockchain and Avalanche’s strategy to lead it.

Morgan walks us through Avalanche’s “real-world adoption first” ethos, explaining how its unique architecture enables enterprises, fintechs, banks, governments, and consumer apps to build purpose-designed blockchains while tapping into a shared liquidity hub.

Robert Leshner — the mind behind Compound, and now the founder of Superstate — believes the next trillion-dollar shift will come from bringing the world’s assets on-chain.

In this episode, Cami sits down with one of DeFi’s earliest pioneers to unpack:

• Why DeFi itself shouldn’t change — but assets will

• How tokenized T-bills, basis strategies, and even equities are finally getting institutional traction

• Why regulatory “tailwinds,” not new laws, unlocked the RWA boom

• The two competing models of tokenized stocks — and why both will win

• What happens when DeFi becomes the infrastructure powering TradFi

• What he’d do differently after Compound’s messy transition to decentralized governance

Robert also gives us a candid breakdown of how Superstate is building “canonical tokenization” — letting public companies turn their actual stock into blockchain-native assets — and why the real breakthrough won’t come from issuance… but from DeFi use cases.

In a world of fast-advancing technology, we are told to trust in our own research. But as the crypto space matures, scams and exploits remain a constant presence. When your assets are gone, they are gone forever, with a near-zero chance of recovery. The old mantra of "Do Your Own Research" falls short against sophisticated threats like address poisoning, advanced malware, and convincing AI deepfakes. How, then, do we build a safer Web3 without sacrificing the decentralized ideals at its core?

Alex Katz, CEO of the Web3 security solution Kerberus, joins us to explore this new frontier. We delve into the philosophical debate of autonomy versus protection, the push for auditing standards, and the future of wallet-native security.

Chapters

00:00 Android vulnerability: why mobile crypto is risky

01:21 Building safer Web3 without sacrificing decentralization

02:10 Crypto’s Wild West: few rules, big risks

03:37 Why scams continue: prosecution, standards, protection gaps

05:44 Kerberus approach and results: zero user losses

06:24 Coverage up to $30K and growth needs

08:24 Why DYOR is insufficient for modern threats

09:33 Traders’ behavior, phishing risk, and automation

11:25 Crypto antivirus vision and malware threats

12:11 Hardware vs. hot wallets: balancing safety and speed

14:41 Address poisoning, clipboard privacy, and deepfakes

20:22 Autonomy vs. protection: beyond user education

24:44 Wallet security should be default, like antivirus

31:51 Getting grandma into Web3 safely

32:29 Lightning round: tools, myths, key lessons

36:04 Where to find Kerberus and closing notes

In the second episode of Ecosystems: Avalanche, we track the protocol’s trajectory, which included a peak valuation of $13 billion, followed by a period of consolidation and strategic redevelopment.

The Defiant founder Camila Russo and Ava Labs' Chief Strategy Officer Luigi D’Onorio DeMeo are joined by founders from BENQI, Euler Labs, and LFJ, who are building on the Avalanche protocol. The conversation covers technical upgrades such as Octane and Etna, aimed at reducing fees, and Interchain Messaging, designed to enhance interoperability between blockchains. It also addresses the strategy to onboard institutional clients, including T. Rowe Price and Wellington, through customized Layer 1 solutions.

Can Avalanche cultivate an ecosystem that thrives without relying on constant incentives, particularly regarding liquidity and user retention? Join us to find out.

In this conversation, May Zabaneh breaks down PayPal’s move into stablecoins with PYUSD and why it matters for financial inclusion. We explore how PYUSD could lower costs for cross-border payments, deliver faster settlement, and plug directly into PayPal’s existing ecosystem. The discussion covers why PayPal built a proprietary stablecoin, early adoption and real-world use cases, and plans for international expansion. We also examine the role merchants play in crypto acceptance, how DeFi and traditional finance are converging, and why interoperability will be essential in the next phase of digital payments.

Chapters

00:00 PayPal’s Vision for Stablecoins

02:47 Why PYUSD? Rationale and Goals

05:18 Stablecoin Advantages: 24/7, Inclusion, Cross‑Border

08:22 Why Proprietary vs Supporting Others

11:06 Unlocking B2B and Rebuilding On‑Chain

12:20 PYUSD in the PayPal/Venmo Ecosystem

14:21 International Expansion and Global Transfers

17:02 Merchant Fit: Categories, Costs, Declines

19:32 User Segments: Crypto‑Curious to Super Users

23:28 Pay with Crypto: Scaling to Larger Merchants

29:38 PYUSD in DeFi: Open and Multi‑Chain

32:01 Liquidity, Partnerships, and the Three Pillars

35:56 Interoperability and Evolving Roles

39:11 AI x Payments: Agent‑Driven Commerce

40:42 Finding the Flywheel, What’s Next

In Web3, we find ourselves in an age of digital phantoms, a "click-farm" era where identity is flimsy and easily fabricated. But what if reputation could be real, portable, and valuable? Animoca Brands co-founder Yat Siu returns to explore this very question, detailing a vision for a trust layer built on zero-knowledge proofs.

He reveals plans for a Hong Kong dollar stablecoin, a joint venture with Standard Chartered and HKT awaiting regulatory approval, and unpacks the Mocaverse ecosystem where staking power and airdrops build a verifiable, cross-chain identity. We also explore the future of Web3 gaming, the coming meta shift from GTA 6, and a bold thesis: why the entire altcoin market may one day eclipse Bitcoin.

Tune in to discover how we might build a more trustworthy digital future.

Chapters

00:18 Solving Web3's "Click Fraud" Problem

01:01 Animoca's Plan for a Hong Kong Stablecoin

03:12 Navigating Hong Kong and China's Regulatory Landscape

09:11 The Composability and Promise of Stablecoins

11:09 Introducing the Mocaverse Loyalty SDK

12:56 Building an Interoperable Digital Identity

15:04 The Search for Trust in a Permissionless World

18:34 Data Custody, GDPR, and Self-Sovereignty

21:02 Can Reputation Live Across Multiple Chains?

27:07 The Limits of KYC and Airdrop Farming

28:49 Staking Power and Airdrops as a Form of Credit

40:34 Rumors of a US Listing for Animoca

45:13 The Future of Web3 Gaming and the GTA 6 Effect

56:22 Why Altcoins May One Day Eclipse Bitcoin

In this episode of The Defiant Podcast, Vinny sits down with Ahmad Shadid—former quant trader turned founder—who redirected the 2022 GPU crunch into a decentralized GPU network and now leads a bold push toward “sovereign superintelligence”: an AI CEO framework that can govern, fund, and scale itself transparently. 

We unpack vibe coding (building with AI at 20x speed), how zero-knowledge proofs and decentralized networks could reshape AI, and why security must keep pace in a world moving faster than audits. We talk leadership, the democratization of software, and the next wave of founders shipping products in days—not months.

We discuss:

• How vibe coding empowers anyone to ship working demos fast

• Where AI CEOs make sense—and where humans still matter

• Why Web3 UX, wallets, and cross-chain could leap forward

• The real bottleneck: security and audits in a 20x build world

• Practical risks for builders and consumers—and how to stay safe

Chapters

00:00 The internet-magnitude moment for building

01:13 Sovereign superintelligence and AI CEO

01:38 Vibe coding: ship 20x faster

01:53 Speed vs. security: the new bottleneck

03:03 From GPU crunch to GPU networks

03:22 Why AI + Web3 will drive the decade

06:51 Will AI replace “managers” or leaders?

09:53 Vibe coding explained—anyone can build

14:05 Tools outpace human code reading

16:30 Building an AI-first product workflow

21:13 Build fast, but build safely

32:00 Toward decentralized AI-managed organizations

37:34 What’s driving the vibe coding wave

39:58 Democratization vs. industry gatekeeping

42:45 Anyone can start—opportunities everywhere

Avalanche says it can finally square the circle: sub‑second finality, a large decentralized validator set, and thousands of sovereign L1s connected through native messaging for shared liquidity.

In the genesis episode of our new ECOSYSTEMS podcast, Camila Russo and guest cohost Luigi D’Onorio DeMeo of Ava Labs unpack the Avalanche story—from Team Rocket’s probabilistic consensus and the stadium sampling intuition, to today’s “city of chains” (C‑Chain liquidity hub, P/X chains, and customizable L1s). We discuss:

• How random sampling achieves speed and safety/liveness guarantees

• Customization without fragmentation via inter-chain messaging (ICM)

• L1 vs L2 trade-offs: shared security vs shared risk, costs, and interoperability

• Enterprise paths (FIFA, Toyota, fintechs), privacy options, and Ava Cloud’s “L1 in minutes”

• Decentralization in practice: validator counts, Nakamoto coefficient, and hardware accessibility

• What real adoption looks like for payments, DeFi, and emerging markets

If Avalanche is right, it has the chance to make finance programmable at scale. If not, we add to the L1 graveyard.

Crypto’s next chapter isn’t a shinier coin—it’s invisible rails. In this episode, we sit down with Aryan Sheikhalian, Research Lead at CMT Digital, to unpack the shift from “crypto as an asset” to crypto as infrastructure: 24/7 markets, instant clearing and settlement, and new structured products that couldn’t exist before. 

We talk about tokenized equities (wrappers vs. native tokenization and why dividends/governance matter), how identity layers and ZK proofs unlock mainstream distribution through banks and fintechs, and where regulation is pushing builders toward partnerships and licensed rails.

Chapters

00:00 Hook: crypto as infrastructure, not asset

01:15 Guest intro and research focus

02:06 Incentives, psychology, and mechanism design

04:03 ICO lessons, maturity, and red flags

07:09 CMT Digital’s thesis and “strictly better”

10:27 Tokenized equities drivers and demand

13:40 Wrappers vs native: dividends, governance

16:06 Fintech rails, velocity, cost efficiency

18:26 Banks, distribution, and competitive incentives

20:29 New assets: GPUs, data, energy tokens

23:23 Identity layers and ZK proofs for scale

25:55 State of crypto VC and fund trends

27:51 Overlooked sectors: DePIN and decentralized data

31:26 Prediction markets and resolution design

34:18 Regulation, licenses, and partnerships

39:45 Market outlook: TVL, stables, volatility

42:45 Founder advice: conviction and user focus

In this episode of The Defiant Podcast, we sit down with Paul Veradittakit, Managing Partner at Pantera Capital, to discuss the explosive growth of Solana, the future of stablecoins, and the evolution of digital asset treasury companies. Paul shares insights on Pantera's $1.2 billion Solana fund, the role of institutional capital in this crypto cycle, and why he believes Solana is poised to outperform Bitcoin and Ethereum. Tune in for a look into the next wave of blockchain innovation, from payments to gaming and beyond.

Chapters

00:00 - Introduction to stablecoins as a practical store of value

01:00 - Guest introduction: Paul Veradittakit of Pantera Capital

01:37 - Pantera’s $1.2 billion Solana fund: Why Solana?

02:36 - Evolution of digital asset treasury companies

04:13 - Pantera’s bullish stance on Solana: Technology and adoption

06:03 - Investment strategies for single-asset treasury companies

08:30 - Managing Solana in Helios: Staking, DeFi, and M&A

10:35 - Addressing Solana’s decentralization and downtime concerns

12:22 - Meme coins and their role in Solana’s ecosystem

18:18 - Stablecoins: A growing demand in Latin America

20:01 - Future use cases for Solana: Payments, AI, and Deepin

23:00 - The rise of specialized blockchains for vertical use cases

26:17 - Stablecoins as a payments hub: Key players to watch

28:14 - Altcoins’ potential to outperform Bitcoin in this cycle

33:15 - Crypto gaming: The underestimated vertical

35:37 - Closing thoughts: Solana’s future and Pantera’s vision

In this episode of The Defiant Podcast, we sit down with Ben Nadareski, CEO and Co-Founder of Solstice Labs, to explore DeFi on Solana and why it’s becoming a magnet for institutional adoption. Ben shares how Solstice Labs is pioneering permissionless, institutional-grade yield strategies and launching the US token, a fully collateralized stablecoin designed to unlock new levels of trust and scalability in DeFi.

We dive into Solana’s unique advantages—speed, low costs, and composability—and how it’s shaking off its “meme chain” reputation to emerge as a serious contender in the blockchain space. Ben also addresses the challenges of scaling trust in crypto, the rise of yield-bearing stablecoins, and how DeFi is empowering users in emerging markets.

We also tackle: How can Solana maintain its edge in a crowded blockchain market? What’s being done to address past network outages? And how can regulation strike the right balance between protecting users and fostering innovation?

Chapters

00:00 – Scaling Trust in Crypto

00:22 – Solana’s DeFi Momentum

01:16 – Why Solana Stands Out

03:43 – From Meme Chain to DeFi Leader

05:57 – The Rise of Yield-Bearing Stablecoins

08:01 – Regulation and Trust in DeFi

12:45 – Solstice Labs and the US Token

18:19 – DeFi’s Role in Emerging Markets

25:13 – The Future of DeFi on Solana

33:08 – Building a Transparent and Scalable DeFi Ecosystem