For a tiny organ, the pituitary gland carries outsized responsibilities in the human body. The size of a pea, the so-called “master gland” produces vital hormones that regulate many important bodily functions, including growth, stress, thirst, and even reproductive development. So it only follows that when things go awry with the pituitary gland, the body can suffer many other problems. Dr. Garni Barkhoudarian is a director of the Pacific Pituitary Disorders Center at Pacific Neuroscience Institute and he joins us today to discuss the positive parts—and the pitfalls—of the pituitary gland.

Christine, one of Dr. Barkhoudarian’s patients, also joins us to share her story of the long and arduous road to get her pituitary tumor diagnosed—and the happy ending she experienced when Dr. Barkhoudarian finally removed the tumor.

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July is Healthy Vision Month, and the National Eye Institute—part of the National Institutes of Health—reminds us to take care of our eyes, by eating a healthy diet and exercising, and also by understanding the connection between our vision and other diseases. Multiple sclerosis, or MS, is one of those diseases. Dr. Barbara Giesser, who specializes in treating patients with MS at Pacific Neuroscience Institute, says that often times, a sudden loss of vision is the first indication that a person might have MS. Dr. Howard Krauss, one of the founders of Pacific Neuroscience Institute and a neuro ophthalmologist, notes that 40 percent of the brain’s activity is related to vision—so it makes sense that a disease of the brain like MS would have such a big impact on vision. We’re revisiting this conversation between these two doctors who have partnered in ways that can detect MS very early in the process, and to monitor the optic nerve to see how well MS treatments are working. Let’s listen in!

Every medical treatment needs to start with a diagnosis, but sometimes that diagnosis proves elusive. Sometimes it may appear that a person has one thing needing treatment, and after that treatment doesn’t work, doctors have to consider other possibilities. Dr. Amit Kochhar at Pacific Neuroscience Institute sees patients with facial paralysis, which is often diagnosed as Bell’s Palsy or Ramsey Hunt Syndrome—but sometimes turns out to be a cancerous tumor on a facial nerve. Doctors try to figure that out as quickly as possible, so they can remove the tumor and begin the work of restoring the patient’s appearance. In today’s episode, Dr. Kochhar describes these various symptoms and explains how he reaches the right diagnosis and treatment for his patients.

If you suffer from seasonal allergies, you probably kept a close eye on the pollen count this spring—and you may have felt those all-too-familiar symptoms that affect one in five people: Congestion, sneezing, runny nose, stuffy nose. That’s known as allergic rhinitis or, more commonly, hay fever. And that’s why now is a good time to revisit this Think Neuro podcast with Pacific Neuroscience Institute’s Dr. Michael Yong, an otolaryngologist with focused training in neuro-rhinology who specializes in treating these seasonal allergies. We’ll learn about what causes allergies and what the different treatment options are. Let’s listen in!

When blood collects in the skull outside the brain and below the outermost layer of tissue surrounding the brain (dura), a subdural hematoma results. This may occur due to head trauma when it is called an acute subdural hematoma. Chronic subdural hematomas may occur due to aging and the increased fragility of blood vessels. The pooled blood may resolve on its own or may require surgical intervention as development of a subdural hematoma can be a life-threatening condition. Symptoms of subdural hematoma can include headache, confusion, change in behavior, dizziness, nausea and vomiting, lethargy or excessive drowsiness, weakness, apathy, and seizures. Subdural hematomas are generally diagnosed by CT scan or MRI imaging.

Ashkan Mowla, MD, FAHA, FAAN, is neuro-interventional surgeon at the Pacific Neuroscience Institute® (PNI). He specializes in minimally invasive endovascular procedures to treat conditions and diseases of the brain and spine, including stroke, brain aneurysm, brain and spine arteriovenous malformation and fistula and carotid and intracranial disease.

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If you have back pain, you are not alone. According to Georgetown University’s Health Policy Institute, nearly 65 million Americans report a recent episode of back pain, and 16 million adults — 8 percent of all adults — experience persistent or chronic back pain and are limited in everyday activities. Dr. Marcus Mazur at Pacific Neuroscience Institute sees people living with back pain and works to find a solution, whether that’s through surgery or through some of the many other available options, including medication, physical therapy, chiropractors and, interestingly, exercises in a swimming pool. In today’s episode, Dr. Mazur discusses all the options, when surgery can help, and things you can do to prevent back pain from affecting you in the first place.

National Stroke Awareness Month is observed in May to promote public awareness about stroke symptoms and prevention. While 800,000 Americans have a stroke every year, many of these can be prevented. It’s particularly critical to recognize when a stroke is happening, because fast treatment can prevent the worst effects. In this Spotlight Replay, Dr. Sandra Narayanan, a neurointerventional surgeon at Pacific Neuroscience Institute who treats people who’ve had strokes, tells us how a healthy lifestyle can help most people avoid a stroke. And she gives an important update to the F.A.S.T. acronym for helping recognize when someone has had a stroke—it’s now BE FAST. Let’s listen in and learn what BE FAST stands for—and keep a stroke from knocking us down!

May is Brain Tumor Awareness Month, which the National Brain Tumor Society calls “a time dedicated to supporting, empowering, and amplifying the voice of the brain tumor community.” The NBTS estimates that more than 1.3 million Americans are living with a brain tumor and, while 73 percent of these are benign, an estimate 18,350 Americans will die of a brain tumor this year. In this Spotlight Replay, we revisit a conversation with Dr. Chester Griffiths, one of the founders of Pacific Neuroscience Institute and a pioneer in the minimally invasive brain surgery that has become one of PNI’s hallmarks. Dr. Griffiths tells how he helps find the path through the brain to the tumor, helps the neurosurgeon remove the disease, and then leads their tiny instruments out again. Let’s listen in!

Dr. Nouzhan Sehati, is a board-certified neurosurgeon who specializes the treatment of a wide variety of brain, spine and spinal cord disorders at Pacific Neuroscience Institute. His expertise is in surgical and nonsurgical management of degenerative, traumatic and neoplastic (tumor) diseases of the brain and spine with a focus on minimally invasive techniques.⁠
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Dr. Sehati believes in clinical excellence and comprehensive care for all of his patients. His compassionate approach involves working as a partner with his patients, honoring patient individuality and dignity, understanding the patient’s needs and preferences, discussing all aspects and options of treatment available, and implementing advanced, state-of-the art techniques for optimal outcomes.⁠

In general, aneurysms are only detected after they have burst although they may sometimes be detected during the course of other tests. Operating on the arteries of the brain may feel scary but there have been tremendous advances in the way that aneurysms are surgically treated. The interventional neuroradiologist has several options for treating the aneurysm from the inside of the blood vessel based on the patient’s status. These kinds of surgery, called endovascular neurosurgery or embolization, are performed using the minimally invasive microcatheter-based approach mentioned earlier. In this way, aneurysms can be treated by coiling, stent coiling, flow diversion, or balloon remodeling. In all these methods, the aim is to prevent blood from pooling in the aneurysm and causing blood clots. The deposited wire coils or cages help to cut off the blood’s access to the aneurysm so that it can flow normally through the blood vessel.

Parkinson’s disease is a neurologic movement disorder. It affects the brain and causes difficulty with movement, with the most common motor symptoms being tremors, stiffness or rigidity of muscles, and slowness of movement. According to the American Parkinson Disease Association, it is the fastest growing neurodegenerative disease in the world, and the second most common after Alzheimer’s disease, with an estimated 1 million people in the U.S. and more than 10 million people worldwide living with Parkinson’s.

In addition to the well-known motor symptoms of tremors, rigidity and slowness, Parkinson’s disease also manifests in non-motor symptoms including sleep problems, constipation, anxiety, depression, and fatigue, among others, which can be present well before any visible motor symptoms.

Dr. Melita Petrossian is a movement neurologist and medical director of Pacific Neuroscience Institute’s Movement Disorders Center. In today’s episode, Dr. Petrossian discusses these non-motor symptoms and explains the different types of testing that can lead to a diagnosis of Parkinson's disease—and what someone living with Parkinson’s may need to consider.

For more information, visit:
https://pacificneuro.org/