Ever gotten a scarlet, hot face after drinking alcohol or know someone who has? Many people felt it as they celebrate the holidays with loved ones, sipping mulled wine, cocktails or champagne. That's because this condition, commonly called "Asian flush" or "Asian glow," affects an estimated half a billion people, who can't break down aldehyde toxins that build up in their bodies. But what if there's a benefit to having Asian glow? Katie Wu, a staff writer for The Atlantic, has looked into the research as to why the condition might have been a powerful tool for some of our ancestors to survive disease. (encore episode)

Questions about other potential tradeoffs for our genetics? Email us at [email protected]. We've love to hear from you and we might cover it in a future episode!Read Katie's article to learn more.Questions about other potential tradeoffs for our genetics? Email us at [email protected]. We've love to hear from you and we might cover it in a future episode!Listen to every episode of Short Wave sponsor-free and support our work at NPR by signing up for Short Wave+ at plus.npr.org/shortwave.This episode was produced by Rebecca Ramirez, edited by Berly McCoy and fact-checked by Brit Hanson. Gilly Moon was the audio engineer.

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Written by Jo Lambert, ‘Hold The Hope’ is now being used as suicide prevention training material by the UK’s National Health Service Mental Health Trust. Emily Kwong speaks with Rhitu Chatterjee about the inner strength of those who live with suicidality, how a song is opening up new conversations for mental health care, and how caregivers can help a person choose life, despite having persistent thoughts of death. 

If you or someone you know may be struggling with suicidal thoughts, contact the 988 National & Suicide Crisis Lifeline by calling or texting 988. 

Listen to the full version of the ‘Hold The Hope’ song here

Read more of Rhitu’s reporting on ‘Hold the Hope’ here

Listen to Rhitu and Emily’s previous conversation about practical ways to help someone at risk of suicide here

Interested in more stories about mental health care? Email us your question at [email protected].

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Dogs are man’s best friend. And it’s no secret that we at Short Wave love cats (Regina has four)! Both of these iconic pets have been domesticated – evolved and adapted to live alongside humans – for millennia. And a recent study suggests that the common raccoon may be on its first steps towards joining them.

So how do scientists look for signs of domestication and what do those signs mean? And could you have a litter box trained raccoon in your lifetime? We talk to the study’s lead author, Raffaela Lesch, to find out.

Interested in more animal science stories? Email us your question at [email protected].


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You may have heard of Ozempic, and other GLP-1 drugs. They’re everywhere. And they typically involve weekly injections — which can have a sticker price of over a thousand dollars a month. And insurance coverage has been tricky to navigate for a lot of people. That’s why there’s a lot of excitement around a new pill form of the drug. NPR Pharmaceuticals Correspondent Sydney Lupkin chats about these experimental pills with host Emily Kwong. 


Check out more of NPR’s coverage about GLP-1s.


Interested in more health stories? Email us your question at [email protected].


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Many countries are frustrated with U.N. climate conferences. While some countries urgently want to transition away from fossil fuels — the main driver of global warming — others are blocking that language from climate agreements. Today on the show, Emily talks with Julia Simon from NPR’s climate desk. She takes us to Brazil and introduces us to a group of countries that are trying something new.

Interested in more science and climate related news? Email us your question at [email protected].

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Humankind has the technology to go to space. Space architect Ariel Ekblaw says the bottleneck now is real estate: getting larger volumes of space stations in orbit. Her company is working on the equivalent of giant, magnetic space Legos—hexagons that could self-assemble in space into livable, workable structures. This episode, host Regina G. Barber talks to her about this space architecture and why she says that the goal isn’t to abandon Earth–but to off-world industries like agriculture and manufacturing in order to build a better Earth.

If you liked this episode, check out our Space Camp series.

Interested in more space tech episodes? Email us your question at [email protected].

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This year, quantum science and computing came up a lot. There have been broad claims that quantum science and engineering could one day help cure diseases, design new materials, optimize supply chains -- or help in other ways not yet fathomable. And, while the Trump administration has made strides to cut scientific funding, quantum research is one of two things they’ve pledged to continue investing in – along with artificial intelligence. Meanwhile, scientists have been hard at work, pushing the research to move quantum engineering from sci-fi to real-world usefulness. All of this got science correspondent Katia Riddle wondering: When will all of this effort actually pay off? She talked to a lot of scientists to figure it out -- and to figure out how much scientist really understand about quantum science. She brings everything she learned onto the show today. 


To hear more Short Wave reporting on quantum clocks, check out this episode: Quantum Mechanics For Beginners

Interested in more quantum science? Email us your question at [email protected].

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Want to be a top notch candidate for hosting alien life? Then there's a few key requirements you should be aware of: Ideally, you're a large object like a moon or a planet; scientists suspect you also have an atmosphere and water; plus, you should orbit your star from a nice mid-range distance — in the "Goldilocks Zone" of habitability. Until recently, you would be competing against TRAPPIST-1 e. It's a planet outside of our solar system. TRAPPIST-1 e is also only 40 light years away, rocky and the same size as Earth, which prompted researchers to investigate whether it also has an atmosphere — and the potential for alien life. A team of researchers has been investigating TRAPPIST-1 e to learn more about its potential. Their answers, recently published in the Astrophysical Journal Letters, say a lot not just about this exoplanet, but about how scientists should refocus their hunt for alien life.

Interested in more space science? Email us your question at [email protected].


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In the 1970’s TV show called Six Million Dollar Man, a test pilot is in a horrible accident. The show’s famous line goes, “We can rebuild him. We have the technology.” Now, in the 2025 book, Replaceable You, science writer Mary Roach explores how people have collectively lived up to the task of rebuilding human bodies when they fail, as well as all the ways we may not quite be there yet. In this episode Regina G. Barber and Mary Roach discuss three chapters of the book, get into everything from iron lungs to private parts and try to answer the question, “How replaceable are you?”


Interested in more science behind the human body? Check out our episodes on synthetic cells and the first pig kidney transplant. Email us your question at [email protected].


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More than 100 million people in the U.S. have some allergy each year. That’s about every 1 in 3 adults. For many, the fix is a bandaid: over-the-counter allergy medications. But there’s another treatment that works to lessen these reactions rather than just manage people’s symptoms, allergy shots. The treatment has been around for over a century and is still popular today. Patients have to take the shots for a few years, and it’s the closest thing science has to a cure. Host Regina G. Barber speaks with Dr. Gina Dapul-Hidalgo about how this immunotherapy works and how certain guidelines to keep your child from developing common food allergies have changed.
Interested in more science behind allergies? Check out our other episodes:

• Having a food allergy? And how your broken skin barrier might be the cause
• Spring Allergies and what to do about them

Have another topic on human biology or consumer health you want us to investigate? Email us your question at [email protected].


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