Dr. Noa Rippel, hematologist at Mount Sinai Hospital in New York, joins Dr. Emily Gutowski to talk through the broad differential diagnosis of leukocytosis, from infection to hematologic malignancies. Together, they discuss the initial workup of leukocytosis, how to interpret a CBC differential, when to be concerned about leukostasis, and when to call hematology.

In this episode, Dr. Emily Gutowski interviews Dr. Malika Madhava about the logistics of TB in the inpatient setting. Together, they break down the approach to suspected tuberculosis, including when to consider TB, how to select isolation precautions, and navigating diagnostic testing.

Dr. Sam Sanders, internist at Bellevue Hospital in NYC, takes us through a case-based review of metabolic dysfunction–associated steatotic liver disease (MASLD), an increasingly common condition. We cover updated terminology, risk stratification using FIB-4 scoring and FibroScans, indications for hepatology referral, and new management strategies to prevent fibrosis progression and cirrhosis.

Gastroenterologist Dr. Sith Sekar joins Navin Kumar to review the management of celiac disease, including tips on the gluten-free diet, the need to check for micronutrient deficiencies, and how to approach the patient with celiac disease who is not responding to a gluten-free diet.

Gastroenterologist Dr. Sith Sekar joins Navin Kumar to review the diagnosis of celiac disease, including the presenting signs and symptoms, the optimal serology screening approach, the role of celiac genetic testing, and how to confirm the diagnosis. They then move into management of celiac disease, including tips on the gluten-free diet, the need to check for micronutrient deficiencies, and how to approach the patient with celiac disease who is not responding to a gluten-free diet.

Gastroenterologist Dr. Sith Sekar joins Navin Kumar to review the important topic of colon cancer screening, including how to calculate individual risk based on family history, options for screening, and some tips to ensure high-quality colonoscopy.

Endocrinologist Brooke Matson joins Walker Redd to outline a practical framework for obesity management, including patient-centered counseling, lifestyle interventions, the use of GLP-1 receptor agonists, as well as when to consider bariatric surgery.

Dr. Navin Kumar, gastroenterologist and RTL co-founder, joins guest-host Ally Scheve to discuss how to treat Small Intestinal Bacterial Overgrowth (SIBO). In this final episode of the three part series, they discuss the approach to antibiotic therapy for SIBO, the importance of understanding the subtype of SIBO when determining a treatment plan, and conclude with non-antibiotic approaches to treatment.

Dr. Navin Kumar, gastroenterologist and RTL co-founder, joins guest-host Ally Scheve to discuss how to diagnose Small Intestinal Bacterial Overgrowth (SIBO). In this episode, they discuss the diagnostic tools for SIBO, how the lactulose breath test works, and important precautions patients should take prior to the breath test to ensure an accurate reading.

Dr. Navin Kumar, gastroenterologist and RTL co-founder, joins guest-host Ally Scheve to discuss the clinical presentation of Small Intestinal Bacterial Overgrowth (SIBO) in this three-part series. In this episode, they discuss the pathophysiology of SIBO, how bacteria in the small intestine lead to GI symptoms, and the risk factors for developing SIBO.

In this special episode, Dr. Mitchell Charap, longtime IM residency program director and master clinician at NYU Langone, walks us through a mystery case that defies expectations. Together, he and host Emily Gutowski explore how illness scripts can both guide and sometimes mislead our diagnostic reasoning, and why the physical exam remains an indispensable tool.