In this episode, Omri Amirav-Drory (NFX), Joe Betts-LaCroix (Retro Bio), and Alex Colville (Age1) discuss the history, recent progress, and hurdles in the longevity industry, including the evaluation of potential founders and business risks. The discussion further encompasses the global fundraising potential and societal impact of the longevity sector, viewing aging as a disease, and the future of longevity drugs. Learn more at - https://nfx.com/bio (0:00) Introduction and Overview of Longevity Science (4:21) Transition from Scientist to Investor: Alex Colville's Journey (8:16) Current Advancements in Biology and Aging Field (12:15) Cutting Edge Topics in Longevity Space (20:02) Evaluating Potential Founders and Startups in the Longevity Space (22:08) Challenges in Longevity Field: FDA Approval and Mission Focus (23:46) Risks and Investment in the Biotech Industry (27:24) Misconceptions and Business Case for Longevity (32:34) Societal Effects and Impact of Longevity Drugs (36:08) Advice and Future Challenges for Founders in the Longevity Field (38:04) Closing Remarks and Thanks

Hercules builds high-quality, enterprise-grade AI solutions based on data extraction, transformation, and verification, while integrating with enterprise systems and tools for maintenance and monitoring. Join NFX general partner James Currier and HerculesAI CEO Alex Babin talk about the latest breakthroughs in the AI space of enterprise companies.

Hercules builds high-quality, enterprise-grade AI solutions based on data extraction, transformation, and verification, while integrating with enterprise systems and tools for maintenance and monitoring.

Join NFX general partner James Currier and HerculesAI CEO Alex Babin talk about the latest breakthroughs in the AI space of enterprise companies.

(0:00) Introduction and background of Alex Babin, CEO of Hercules AI (3:49) Origin story and initial focus of Hercules AI (8:28) Reflections on the early days and current state of Hercules AI (13:08) Hercules AI's mission, vision, and the problem they are solving (16:04) Importance of supporting existing infrastructure and Hercules AI's pricing model (19:33) Introduction to Rosetta Stone, Hercules AI's new model (23:39) Challenges of integrating AI into enterprise business processes (28:02) Predictions for the AI market in the next 5 to 10 years (31:26) The battle between Google and OpenAI in the AI market (34:28) Closing remarks and appreciation

This is an essay readout using an AI voice clone of NFX general partner, Pete Flint. AI has the potential to smooth out many links in the real estate production chain and create a cascade that will close the productivity gap. This essay reveals what’s on the way and how founders can seize this opportunity. Read the full essay here - https://www.nfx.com/post/ai-revolution-proptech

Read the full essay here - https://www.nfx.com/post/ai-revolution-proptech

(0:00) Introduction and AI voice experiment (2:35) The challenges and opportunities in digitizing the real estate industry (6:31) AI applications in zoning, permitting, and speeding up renovations (9:28) Opportunities and challenges for B2B startups and access to data (12:07) Considerations for founders and identifying control points in the real estate AI field (14:22) The rise of AI co-piloting in high-stakes industries and overlooked opportunities (15:13) The impact of AI in architecture, engineering, and construction (15:45) Closing remarks and invitation for early-stage founders in real estate and AI

Morgan Beller calls up Raed Khawaja - CEO & Co-Founder at Open - to catch up and talk about the current movement around one's 'inner-space'. Open is a social space for meditation, movement, and practice — on and offline, who’s raised close to $15M to help friends be present together. They blend old and new to bring you to the here and now on their app, in person at their Venice Beach studio, and even in the sky on JetBlue airlines. Their hybrid method strengthens the mind-body connection. NFX operates as a pre-seed and seed stage VC that is transforming how true innovators are funded - subscribe, share, and stay tuned for more episodes of 'Phone a Friend' with General Partner Morgan Beller.

Morgan Beller calls up Raed Khawaja - CEO & Co-Founder at Open - to catch up and talk about the current movement around one's 'inner-space'.

Open is a social space for meditation, movement, and practice — on and offline, who’s raised close to $15M to help friends be present together. They blend old and new to bring you to the here and now on their app, in person at their Venice Beach studio, and even in the sky on JetBlue airlines. Their hybrid method strengthens the mind-body connection.

NFX operates as a pre-seed and seed stage VC that is transforming how true innovators are funded - subscribe, share, and stay tuned for more episodes of 'Phone a Friend' with General Partner Morgan Beller.

(0:00) Introduction and welcome to the podcast (2:39) Topic: The Power of Friendships and Networking (4:41) Topic: Open Office Experiment at NFX (7:33) Topic: The Impact of Meditation and Mindfulness Practices (13:14) Topic: Destigmatization and Critical Mass of Wulu Practices (18:24) Topic: Scaling the Magic of In-Person Experiences (23:10) Topic: Market Size and Potential Audience for Wellness Practices (26:08) Topic: Role of Breathwork in Wellness and Decision Making (32:02) Topic: Current Obsessions in the Wellness Space (33:47) Topic: Introduction to Death Meditation

This is an essay readout using an AI voice clone of NFX general partner, James Currier. Generative Tech is the next step in software. It’s a new level of human-machine partnership. It turns deep learning engines into collaborators to generate new content and ideas nearly like a human would. This area is so new, and moving so fast, you can have an advantage in your chosen area in a few months… for now.

Read the full essay here - https://www.nfx.com/post/generative-tech

(0:00) Introduction: James Currier on AI and generative tech (1:41) New Internet topology with generative tech (3:44) Generative tech and the creative process (6:10) The future of generative tech and advice for founders (8:36) Replacing curation with creation in generative tech (11:54) Data network effects and the importance of hyper-local datasets (14:01) Achieving uniqueness at scale with generative tech (15:20) Picking the right idea and fast growth strategies in generative tech (17:15) Balancing business growth with societal responsibility (18:32) Closing, contact details, and subscription information

This is an essay readout using an AI voice clone of NFX general partner, James Currier. Every 14 years there’s a tech revolution, and we have now entered the Generative Tech revolution. Anything you’re interested in, anything you’re working on is going to be impacted by generative tech and generative AI. In addition to the AI model companies, many unicorns and decacorns will be built, starting now. We’re already seeing three types of winners. If you can wrap your mind around what is happening with these new capabilities and see the future better than others, there is no better time to build something huge.

Read the full essay here - https://www.nfx.com/post/3-waves-generative-ai-startups

(0:00) Introduction and AI Voice Experiment (0:32) Overview of Generative Tech Startups and Their Impact (1:32) First Wave of Generative Tech: Wrappers Around AI Models (2:22) NFX Generative Tech Market Map: An Insight into the Current Market (3:10) Third Wave of Generative Tech: Visionary and Non-Obvious Innovations (4:13) Conclusion and Request for Audience Feedback

This is an essay readout using an AI voice clone of NFX general partner, James Currier. The AI revolution just ratcheted up the speed bar for startups. You think you’re moving fast enough. You’re not. Speed is the number one advantage of a startup. But now that generative AI here, your definition of speed has to increase 10x.

Read the full essay here - https://www.nfx.com/post/speed-and-ai

(0:00) Introduction to AI and its future implications (1:16) NFX's perspective on generative AI (2:16) The need for founders to move faster into the AI market (3:39) The importance of resetting speed benchmarks (4:37) The new speed bar for product launches with generative AI (4:59) Advice for founders to adopt a faster mindset (7:56) Conclusion: The importance of a fast mindset in the age of AI (8:11) Feedback request and how to subscribe to the NFX podcast

There’s a concept in network theory called Preferential Attachment. When one node gets ahead, it attracts more resources, and more attention. It's a snowball effect. PR for your company works the same way. Once you become the biggest node, more resources flow to you. Today, NFX General Partner James Currier sits down with Vijay Chattha, founder of PR agency VSC to reveal how to build that attention flywheel. VSC has worked with NFX unicorn companies like Mammoth Biosciences, Poshmark, and Outdoorsy, to build attention and momentum from the ground up. (0:00) Introduction and Background of Vijay Chattha (5:06) Vijay Chattha's Approach to PR and Criteria for Representing Companies (10:41) The Importance of a Company's Storytelling Runway and Marketability (19:26) Authenticity, Audience Understanding, and the Role of Journalists in Today's Media Landscape (25:28) Setting Goals and Audience Targeting for Seed Stage Startups (30:40) Case Study: Successful PR Strategy with Mammoth Biosciences and the Concept of Preferred Attachment in PR (37:44) The Role of Funding in Storytelling and Strategies for Early-Stage Startups (43:19) Risks and Rewards of Founders Using Social Media and Choosing the Right Medium for Communication (47:10) Common Mistakes Founders Make in Communication and the Shifting Landscape of Media Coverage (51:15) When to Hire a PR Firm and the Role of Investors in PR and Storytelling

The transition from Founder to CEO is a watershed moment in your company, and in your life. A great Founder creates something from nothing. A great CEO takes the next step, and builds mechanisms of success. They turn that vision into a well-functioning machine. Becoming a great CEO is a matter of tactics and personal growth. Today, NFX General Partner Gigi Levy-Weiss reveals how to get there, with special guest Avishai Abrahami, the founder of Wix. Avishai built Wix into a company of about 5,000 people, with 1.4 billion in revenue. They’ll cover how Founders can become great CEOs, measurements that most startups miss, the difference between good failure and bad failure, and more. (edited) (0:00) Introduction: Gigi Levy-Weiss and Avishai Abrahami (1:29) The Success Journey of Wix (5:14) Mechanisms for Success and Role of a Manager in a Startup (10:02) Talent Acquisition and HR Processes in Startups (16:17) The Evolution of Talent Requirements as the Company Grows (19:05) The Importance of Measuring Business KPIs (22:34) The Role of Failure and Experimentation in Startups (25:28) Efficient Meeting Management in Growing Companies (30:56) The Significance of Clear Communication and Transparency in a Company (40:27) Efficiency of Remote Work vs. Office Work in Startups (44:55) Closing thoughts: Winners always want the ball when the game is on the line

There are two parts to building a bioplatform: you have to focus on the science, then you have to think about the business side. When do you partner? When do you develop your own products? How can you determine the real value of a deal? How do you build a strategic network? What avenues are Founders overlooking right now? These are questions our companies ask us all the time. Today, Head of NFXBio Omri Amirav-Dory, Yael Gruenbaum-Cohen, a venture partner at aMoon Fund, and Peter Nell, former Chief Business Officer and head of Therapeutics at Mammoth Biosciences, are charting a roadmap for successful bioplatform business development. (0:00) Introduction by Omri Amirav-Drory and Guest Introductions: Peter Neil and Yael Gruenbaum-Cohen (4:06) Discussion on NFX's Investment Focus and the Role of Business Development in Startups (11:33) Importance of Strategic Partnerships and the Right Deals for Company Growth (17:19) Building Trust and Relationships in Business Development, Importance of Patience (23:13) The Role of Soft Skills, Evidence Required for Partnerships and the Relevance of Animal Models in Funding (30:04) Common Mistakes Founders Make During Deal-Making and a Hypothetical Case Study Discussion (36:29) The Potential and Challenges of Commercializing Technology as a Service in Platform Companies (38:48) The Dilemma of Balancing Pipeline Advancement and Financial Opportunities in Startups (41:00) Exploring New Avenues for Business Development: Partnering and Competition (43:49) Final Thoughts on Business Development in the Current Funding Climate and Closing Remarks by Omri Amirav-Drory

There’s huge value in integrating tech and bio. But many tech entrepreneurs don’t realize what they can bring to the field. Tech entrepreneurs: you can come to bio, if you learn to speak the language. Today, head of NFX Bio Omri Amirav-Drory sits down with his former co-founder at Genome Compiler, and Founder of Mana.bio Yogev Debbi. Yogev has bridged the gap between tech and bio several times in his career. Here’s how to build a culture of trust, leverage your fresh perspective, and build impactful companies at the intersection of tech and bio. (0:00) Omri Amirav-Drory introduces the episode and guest, Yogev Debbi (5:59) Debbi's experience with Twist Biosciences and the impact of CRISPR (10:15) Debbi's decision to start MannaBio and its mission (12:45) The complexity and challenges of developing new delivery vehicles in biotherapeutics (17:28) The importance of automation and efficiency in biotech (22:33) Applying tech concepts to improve efficiency in bio (26:30) Building the right team for a tech-bio startup (32:25) Bridging the gap between tech and bio teams for innovation (38:06) The evolution of problem-solving in startups (41:17) The crucial elements of a successful startup: Team, Technology, and Market (43:26) The potential of biology in solving world problems