Talking Precision Medicine

Genialis

Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.

  • 39 minutes 36 seconds
    Ian Simon | When following the science isn’t enough: risk, communication, and the future of biotechnology | TPM podcast #52

    In this episode, I’m joined by my longtime friend Ian Simon, Head of Biotechnology at Aspis Intelligence. Ian’s path runs from grad school vaccine research at Yale to senior roles at the White House, HHS, NIH, the State Department, and the Office of Long Covid. We talk about de-risking young biotech companies, what Covid taught us about science and public health, and how new technologies like AI might change how we do science altogether. 

    ⁠⁠⁠TPM E52 highlights >⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

    Episode 52 links:


    12 December 2025, 4:48 pm
  • 36 minutes 27 seconds
    Michelle Chen | Using AI to derisk gene therapy and genetic medicine | TPM podcast #51

    In this episode Rafael sits down with Michelle Chen, President and CEO of Form Bio, a techbio company using AI to advance genome engineering and the development of genetic medicines. Michelle shares her zigzag journey from scientist to executive, how her team is tackling the biggest bottlenecks in gene therapy, and why AI has become essential in designing safer, more effective treatments.

    ⁠⁠TPM E51 highlights >⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

    Episode 51 links:


    13 November 2025, 8:37 am
  • 44 minutes 44 seconds
    Mike Rossi, ConcertAI | Real world data and artificial intelligence turn anecdote to evidence | TPM podcast #50

    Today I’m joined by Mike Rossi, Vice President of Translational Science and Multi-modal Real-World Evidence Solutions at ConcertAI. Mike has built a career at the intersection of genomics, data science, and oncology, helping to bridge the gap between research and real-world clinical practice. We talk about what real-world data really means, how it becomes actionable evidence, and what it takes to turn the messy reality of patient care into insight that changes lives.

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    30 October 2025, 9:06 am
  • 44 minutes 30 seconds
    Mida Pezeshkian, Stema_cg | Launching products in healthcare: The most important framework is flexibility | TPM podcast #49

    Joining us on this episode is Mida Pezeshkian, an old colleague and friend. Mida’s career has spanned from the depths of stem cell science as a student to her current focus on product management in healthcare. We talk about what it really takes to launch products in this space, and how she helps customers bring truly transformational innovations to market.

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    29 August 2025, 12:40 pm
  • 43 minutes 24 seconds
    Michael Montalto, Amgen | How to have the biggest impact on patients: a career of invention, innovation, and implementation | TPM podcast #48

    Today on the show, I’m joined by Michael Montalto, vice president of precision medicine at Amgen. Amgen is widely recognized as one of the most successful pharmaceutical companies in translating research and development into approved therapies. A key part of that success comes from their focus on precision medicine, and Mike brings a unique perspective from the forefront of that work.


    ⁠⁠TPM E48 highlights >⁠⁠⁠⁠⁠⁠⁠⁠⁠

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    24 July 2025, 9:36 am
  • 42 minutes 43 seconds
    Tom Neyarapally, Archetype Therapeutics | A new paradigm for generative AI drug discovery: more accurate shots on a much wider goal | TPM podcast #47

    Joining us on this episode is Tom Neyarapally, co-founder and CEO of Archetype Therapeutics, an exciting new AI-driven company in the drug discovery space. Archetype is an AI-native biotech pioneering the use of generative chemogenomics and patient clinicogenomic data to virtually screen billions of potential drug candidates each day.

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    24 June 2025, 7:13 pm
  • 50 minutes 2 seconds
    Stéphane Budel, DeciBio | Precision medicine is our future and our fate | TPM podcast #46

    Stéphane Budel, founding partner at DeciBio, joins the Talking Precision Medicine Podcast to explore the future of the field. He unpacks how liquid biopsy, multi-omics, and AI are opening new doors for personalized care, why the diagnostics business model is holding innovation back, and what it will take to make complex tech usable for clinicians and patients alike.

    ⁠TPM E46 highlights >⁠⁠⁠⁠⁠⁠⁠⁠

    Episode 46 links:

    DeciBio’s White Paper on AI in Drug Development (with contributions from Rafael Rosengarten)

    19 May 2025, 10:04 am
  • 46 minutes 10 seconds
    Anna Berkenblit & Sudheer Doss, PanCAN | On a mission to beat an ignoble killer: pancreatic cancer | TPM podcast #45

    Today’s guests are Anna Berkenblit, Chief Scientific and Medical Officer at the Pancreatic Cancer Action Network, and Sudheer Doss, Chief Business Officer at PanCAN. The Pancreatic Cancer Action Network is the leading organization dedicated to advancing progress against pancreatic cancer. It empowers patients and caregivers, drives early detection strategies, and revolutionizes the development of advanced and personalized treatments.

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    22 April 2025, 10:41 am
  • 38 minutes 35 seconds
    Najat Khan | Radical Transformation: Becoming a Medicines Company with End-to-End AI | TPM #44

    Today’s guest is Najat Khan, Chief R&D Officer and Chief Commercial Officer at Recursion Pharmaceuticals.

    Recursion is widely recognized as one of the most visible—and so far, most successful—companies to emerge from the tech-bio movement. Many consider it the current industry leader.

    It has become an iconic name in the field of artificial intelligence for drug discovery.


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    Episode 44 links:

    28 March 2025, 8:49 am
  • 43 minutes 19 seconds
    Ryan Fukushima | Reinventing diagnostics: The superpower of not knowing what can’t be done | TPM #43

    What a pleasure to welcome today’s guest, Ryan Fukushima, chief operating officer of TempusAI. Not only has Ryan helped build Tempus brick by brick from the earliest days, he is also CEO of Pathos AI, a biotech company using real world data and AI to develop true precision medicines. I don’t know how he juggles it all, but unless you’ve been hiding out these last few years, Tempus has become a household name in our industry, completing a highly successful IPO last year. But no need to take my word for it, come on in and have a listen!


    TPM E43 highlights >⁠⁠⁠⁠⁠⁠


    Episode 43 links:

    Ryan Fukushima on LinkedIn⁠

    ⁠Tempus AI⁠

    ⁠Pathos⁠

    ⁠Tempus announces multi-year collaboration with Genialis

    26 February 2025, 9:18 am
  • 47 minutes 34 seconds
    The journey to the top of life sciences technology: a lifetime of listening and learning | Talking Precision Medicine #42

    Today my guest is Joydeep Goswami, newly appointed President and CEO of the storied biotechnology company LGC. Joydeep is also a strategy advisor to Genialis. Join us as we discuss his remarkable career and lessons learned at each step of the way.

    Come on in and have a listen.

    Episode 42 links:



    31 January 2025, 8:43 am
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