<p>Ever wanted to know how music affects your brain, what quantum mechanics really is, or how black holes work? Do you wonder why you get emotional each time you see a certain movie, or how on earth video games are designed? Then you’ve come to the right place. Each week, Sean Carroll will host conversations with some of the most interesting thinkers in the world. From neuroscientists and engineers to authors and television producers, Sean and his guests talk about the biggest ideas in science, philosophy, culture and much more.</p>
There is something special about gravity. After decades of effort, there is still no convergence on the right way to reconcile Einstein's theory of general relativity with the framework of quantum mechanics. But a number of intriguing ideas have arisen along the way, including black hole radiation, the wave function of the universe, the AdS/CFT correspondence, and the role of quantum information theory. Theoretical physicist Daniel Harlow has made significant contributions to our understanding of information loss in black holes; in this conversation we turn those insights onto quantum cosmology, with potentially significant implications for how quantum mechanics itself works.
Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/03/30/349-daniel-harlow-on-what-quantum-gravity-teaches-us-about-quantum-mechanics/ Support Mindscape on Patreon.Daniel Harlow received his Ph.D. in physics from Stanford University. He is currently an associate professor of physics at the Massachusetts Institute of Technology. Among his awards are a Packard Fellowship and the New Horizons in Physics Prize.
"Lamarkism" is a term often attached to a seemingly discredited idea in evolutionary biology: that one organism could acquire characteristics (e.g., becoming stronger through exercise) that would then be inherited by its descendants. This is a different story than the one ultimately told by the modern synthesis of evolutionary biology, according to which inheritance passes through our genome (which doesn't know that we've been working out). In her book The Power of Life: The Invention of Biology and the Revolutionary Science of Jean-Baptiste Lamarck, historian of science Jessica Riskin argues that this picture is too simple, and that Lamarck made contributions we should still pay attention to: most significantly, the idea that organisms have a creative agency of their own, in addition to the influences of the outside world.
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Jessica Riskin received her Ph.D. in history from the University of California, Berkeley. She is currently the Frances and Charles Field Professor of History at Stanford University. Among her awards are the Patrick Suppes Prize in the History of Science and the J. Russell Major Award for French history. Her books include The Restless Clock and Genesis Redux, and she is a frequent contributor to the New York Review of Books.
In the 18th century, philosopher Jeremy Bentham suggested the Panopticon as a model of a prison where inmates could be constantly observed by just a single prison guard. Although his original idea was never built, the word has come to indicate any system of social control through constant surveillance. Nowadays, we are close to creating such a system, not for prisons, but for our everyday lives. The data about our whereabouts and doings is collected by our smart devices, and available for search by the authorities. I talk with law professor Andrew Guthrie Ferguson about the new reality, as discussed in his book Your Data Will Be Used Against You: Policing in the Age of Self-Surveillance.
Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/03/16/347-andrew-guthrie-ferguson-on-how-your-data-will-be-used-against-you/Support Mindscape on Patreon.
Andrew Guthrie Ferguson received his J.D. from the University of Pennsylvania, and an LL.M. from Georgetown University. He is currently a professor of law at George Washington University Law School. He is a member of the American Law Institute (ALI) and was an Advisor to the ALI Principles of the Law, Policing Project. He previously worked as a supervising attorney at the Public Defender Service for the District of Columbia.
Intelligence is a many splendored thing, especially when it comes to comparisons between species. Chimpanzees are better than humans at some numerical tasks, but less good at understanding what numbers actually mean. One window on the ways that species differ is how they play amongst themselves. I talk with anthropologist and cognitive scientist Erica Cartmill about modes of play and other social behaviors among various species, and what they reveal about the ways we all think.
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Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/03/09/346-erica-cartmill-on-how-human-and-animal-minds-think-and-play/
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Erica Cartmill received her Ph.D. in psychology and neuroscience from the University of St. Andrews. She is Professor of Cognitive Science, Anthropology, Animal Behavior, Psychology, and Informatics at Indiana University, Bloomington and an External Professor at the Santa Fe Institute. She is the co-chair of the EVOLANG conferences and the co-director of the Diverse Intelligences Summer Institute. She is co-director of the Possible Minds lab at IU, and also manages the Observing Animals project, which asks for public input on how animals interact with each other.
Welcome to the March 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!
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Blog post with questions and transcript: https://www.preposterousuniverse.com/podcast/2026/03/02/ama-march-2026/
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Behaving rationally involves facing up to conditions of uncertainty; we never navigate the world with perfect confidence. Sometimes we are uncertain about the way the world is, but we can also be uncertain about our place within the world. This kind of situation arises in cosmology (where the relevant world can extend very far in space or time), and also in quantum mechanics (where new worlds might be created at any measurement), but also when we are simply unsure about the future history of humanity or whether we live in a computer simulation. I talk with philosopher Adam Elga about how to deal with these unique kinds of uncertainties.
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Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/02/23/345-adam-elga-on-being-rational-in-a-very-large-universe/
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Adam Elga received his Ph.D. in philosophy from MIT. He is currently a professor of philosophy at Princeton University. His research involves decision and game theory, epistemology, philosophy of probability, philosophy of mind, and philosophy of science.
It's possible to look at the course of history over the past few centuries and discern a movement toward increasing democracy, freedom, and individual rights -- "liberalism," in the political-philosophy sense of the term. But such movement isn't inevitable or irreversible, and in very recent times there have been both intellectual arguments explicitly pushing back against the liberal consensus, and political movements that are more openly nativist and authoritarian. I talk with Adam Gurri, the editor-in-chief of Liberal Currents, a web site that "publishes writers of diverse perspectives who share an unflinching commitment to freedom, pluralism, and democracy, in opposition to authoritarianism at home and around the world."
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Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/02/16/344-adam-gurri-on-liberal-democracy-and-how-to-fight-for-it/
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Adam Gurri received an M.A. in Economics from George Mason University. He is the co-founder and Editor-in-Chief of Liberal Currents.
For all that human beings spend a lot of their time thinking, it's far from obvious what that process actually entails. Part of it amounts to classical logical reasoning. But an even bigger part involves reasoning with probability and uncertainty. And some of it is governed by unavoidable limitations on time and accuracy. Psychologist and computer scientist Tom Griffiths suggests that we have thought about it enough to feel that we have come to understand some general principles, which he explains in his new book The Laws of Thought: The Quest for a Mathematical Theory of Mind.
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Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/02/09/343-tom-griffiths-on-the-laws-of-thought/
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Tom Griffiths received his Ph.D. in psychology from Stanford University. He is currently Professor of Psychology and Computer Science at Princeton University, Director of the Computational Cognitive Science Lab, and Director of the Princeton Laboratory for Artificial Intelligence. He is the co-author of Algorithms to Live By: The Computer Science of Human Decisions, as well as the upcoming The Rational Use of Cognitive Resources.
Welcome to the February 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!
Blog post with AMA questions and transcript: https://www.preposterousuniverse.com/podcast/2026/02/02/ama-february-2026/
Note that Mindscape now has a new hosting provider, Libsyn. (Actually a return home, as that was my first host when Mindscape was launched.) Things seem to be going smoothly, but let us know if there are any technical glitches.
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Evolution with natural selection involves an intricate mix of the random and the driven. Mutations are essentially random, while selection pressures work to prefer certain outcomes over others. There is tremendous divergence of species over time, but also repeated convergence to forms and mechanisms that are unmistakably useful. We see this clearly in eyes and fins, but the basic pattern also holds for brains and forms of social organization. I talk with philosopher Rachell Powell about what these ideas mean for humans, other terrestrial species, and also for forms of life we have not yet encountered.
Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/01/26/342-rachell-powell-on-evolutionary-convergence-morality-and-mind/
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Rachell Powell received her Ph.D. in philosophy from Duke University. She is currently a Professor of Philosophy at Boston University. She has held fellowships at the National Humanities Center, the American Council of Learned Societies, the Konrad Lorenz Institute for Evolution and Cognition Research, the National Evolutionary Synthesis Center, the Berlin School of Mind and Brain at Humboldt University, and the Center for Genetic Engineering and Society at North Carolina State University.
"Things fall apart; the centre cannot hold," wrote W.B. Yeats. I don't know about the centre, but the tendency of things to fall apart is pretty universal, ultimately due to the Second Law of Thermodynamics. Anyone living in a society or involved with technology must therefore be interested in the concept of maintenance -- keeping systems working. In his book Maintenance: Of Everything, Part One, Stewart Brand looks at the challenges and rewards of this concept.
Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/01/19/341-stewart-brand-on-maintenance-as-an-organizing-principle/
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Stewart Brand received an undergraduate degree in biology from Stanford University. He was the founder, editor, and publisher of the Whole Earth Catalog, which won a National Book Award. He founded the journal CoEvolution Quarterly and the WELL electronic community, and was a co-founder of the Long Now Foundation. He has been called "the 20th century's top influencer."