• 1 hour 11 minutes
    353 | Alvin Roth on the Economics of Morally Contested Markets

    Economic markets are efficient ways of deciding fair prices, at least in ideal circumstances of perfect competition, information, and choice. But there is more to life than fair prices. Two people might decide on a fair price to carry out a contract killing, but society generally frowns on the idea. Many examples of morally contestable markets feature less consensus than that one: sex work, drugs, selling organs, adopting children. In his new book Moral Economics, economist Alvin Roth investigates how we should reason through such tricky cases, and what we can learn from them.

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    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/05/11/353-alvin-roth-on-the-economics-of-morally-contested-markets/

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    Alvin Roth received his Ph.D. in operations research from Stanford University. He is currently the Craig and Susan McCaw Professor of Economics at Stanford University and the Gund Professor of Economics and Business Administration Emeritus at Harvard. He was President of the American Economic Association in 2017. He and Lloyd Shapley shared the 2012 Nobel Prize in Economics for "the theory of stable allocations and the practice of market design."

    11 May 2026, 10:00 am
  • 4 hours 6 minutes
    AMA | May 2026

    Welcome to the May 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!

    Blog post with AMA questions and full transcript: https://www.preposterousuniverse.com/podcast/2026/05/04/ama-may-2026/

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    4 May 2026, 11:56 am
  • 1 hour 14 minutes
    352 | Bing Brunton on Connecting the Connectome to the Body

    The connectome is the wiring diagram of a brain, a big matrix that tells us what neurons talk to what other neurons. Understanding it is an important step to understanding how brains work, but a long way from the final answer. A big next step is understanding how neuronal circuits connect to and guide bodily behavior. Very recent work on mapping the fruit-fly connectome has brought us closer to that goal. I talk with neuroscientist Bing Brunton about the connectome, how we can study it to understand bodily motion in flies and other creatures, and where it's all taking us.

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    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/04/27/352-bing-brunton-on-connecting-the-connectome-to-the-body/

    Bing Wen Brunton received her Ph.D. in neuroscience from Princeton University.. She is currently a Professor of Biology and the Richard & Joan Komen University Chair at the University of Washington, with affiliations at the eScience Institute for Data Science, the Paul G. Allen School of Computer Science & Engineering, and the Department of Applied Mathematics.

    27 April 2026, 10:00 am
  • 1 hour 15 minutes
    351 | Peter Singer on Maximizing Good for All Sentient Creatures

    Peter Singer has been an influential philosopher for a number of decades. He was a significant early voice in animal rights, has been a leading thinker of utilitarianism, and helped inspire the effective altruism movement. In this podcast episode, we try our best to talk about all of those things -- working from metaethical questions of consequentialism vs. other approaches, to specific flavors of utilitarianism, the practical demands that ethics places on people, the rights of animals, and the decisions we make at the end of our lives.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/04/20/351-peter-singer-on-maximizing-good-for-all-sentient-creatures/

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    Peter Singer received his B.Phil. in philosophy from the University of Oxford. He retired from Princeton University in 2023, and now lives in Melbourne, Australia. He is the author of a number of influential books, including Animal Liberation (1975). He has been named a Companion of the order of Australia, and is a winner of the Berggruen Prize. He is the founder of the charity The Life You Can Save. He and philosopher Kasia de Lazari Radek are co-hosts of the Lives Well Lived podcast (YouTube, Spotify, Apple).

    20 April 2026, 11:43 am
  • 1 hour 21 minutes
    350 | J. Eric Oliver on the Self and How to Know It

    We are more familiar with ourselves than with anything else in the universe, but we generally don't come very close to really understanding what our "self" is. That's not too surprising, as selves are very complicated and we are burdened by all sorts of biases. Today's guest is J. Eric Oliver, who has been teaching a popular course at the University of Chicago called "The Intelligible Self." His academic specialty is political science, but he brings together ideas from psychology, neuroscience, and a broad swath of the humanities. His view is summarized in his recent book, How to Know Yourself: The Art and Science of Discovering Who You Really Are.

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    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/04/13/350-j-eric-oliver-on-the-self-and-how-to-know-it/

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    J. Eric Oliver received his Ph.D. in political science from the University of California, Berkeley. He is currently a Professor of Political Science at the University of Chicago. His research interests include contemporary American politics, suburban and racial politics, political psychology, and the politics of science. He is the host of the podcast Knowing: With Eric Oliver.

    13 April 2026, 12:28 pm
  • 3 hours 46 minutes
    AMA | April 2026

    Welcome to the April 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!

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    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/04/06/ama-april-2026/

    Support Mindscape on Patreon.

    5 April 2026, 1:37 pm
  • 1 hour 25 minutes
    349 | Daniel Harlow on What Quantum Gravity Teaches Us About Quantum Mechanics

    There is something special about gravity. After decades of effort, there is still no convergence on the right way to reconcile Einstein's theory of general relativity with the framework of quantum mechanics. But a number of intriguing ideas have arisen along the way, including black hole radiation, the wave function of the universe, the AdS/CFT correspondence, and the role of quantum information theory. Theoretical physicist Daniel Harlow has made significant contributions to our understanding of information loss in black holes; in this conversation we turn those insights onto quantum cosmology, with potentially significant implications for how quantum mechanics itself works.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/03/30/349-daniel-harlow-on-what-quantum-gravity-teaches-us-about-quantum-mechanics/ Support Mindscape on Patreon.

    Daniel Harlow received his Ph.D. in physics from Stanford University. He is currently an associate professor of physics at the Massachusetts Institute of Technology. Among his awards are a Packard Fellowship and the New Horizons in Physics Prize.

    30 March 2026, 1:36 pm
  • 1 hour 15 minutes
    348 | Jessica Riskin on Jean-Baptiste Lamarck and Life as Creative Agency

    "Lamarkism" is a term often attached to a seemingly discredited idea in evolutionary biology: that one organism could acquire characteristics (e.g., becoming stronger through exercise) that would then be inherited by its descendants. This is a different story than the one ultimately told by the modern synthesis of evolutionary biology, according to which inheritance passes through our genome (which doesn't know that we've been working out). In her book The Power of Life: The Invention of Biology and the Revolutionary Science of Jean-Baptiste Lamarck, historian of science Jessica Riskin argues that this picture is too simple, and that Lamarck made contributions we should still pay attention to: most significantly, the idea that organisms have a creative agency of their own, in addition to the influences of the outside world.

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    Jessica Riskin received her Ph.D. in history from the University of California, Berkeley. She is currently the Frances and Charles Field Professor of History at Stanford University. Among her awards are the Patrick Suppes Prize in the History of Science and the J. Russell Major Award for French history. Her books include The Restless Clock and Genesis Redux, and she is a frequent contributor to the New York Review of Books.

    23 March 2026, 11:42 am
  • 1 hour 8 minutes
    347 | Andrew Guthrie Ferguson on How Your Data Will Be Used Against You

    In the 18th century, philosopher Jeremy Bentham suggested the Panopticon as a model of a prison where inmates could be constantly observed by just a single prison guard. Although his original idea was never built, the word has come to indicate any system of social control through constant surveillance. Nowadays, we are close to creating such a system, not for prisons, but for our everyday lives. The data about our whereabouts and doings is collected by our smart devices, and available for search by the authorities. I talk with law professor Andrew Guthrie Ferguson about the new reality, as discussed in his book Your Data Will Be Used Against You: Policing in the Age of Self-Surveillance.

    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/03/16/347-andrew-guthrie-ferguson-on-how-your-data-will-be-used-against-you/

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    Andrew Guthrie Ferguson received his J.D. from the University of Pennsylvania, and an LL.M. from Georgetown University. He is currently a professor of law at George Washington University Law School. He is a member of the American Law Institute (ALI) and was an Advisor to the ALI Principles of the Law, Policing Project. He previously worked as a supervising attorney at the Public Defender Service for the District of Columbia.

    16 March 2026, 12:43 pm
  • 1 hour 28 minutes
    346 | Erica Cartmill on How Human and Animal Minds Think and Play

    Intelligence is a many splendored thing, especially when it comes to comparisons between species. Chimpanzees are better than humans at some numerical tasks, but less good at understanding what numbers actually mean. One window on the ways that species differ is how they play amongst themselves. I talk with anthropologist and cognitive scientist Erica Cartmill about modes of play and other social behaviors among various species, and what they reveal about the ways we all think.

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    Blog post with transcript: https://www.preposterousuniverse.com/podcast/2026/03/09/346-erica-cartmill-on-how-human-and-animal-minds-think-and-play/

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    Erica Cartmill received her Ph.D. in psychology and neuroscience from the University of St. Andrews. She is Professor of Cognitive Science, Anthropology, Animal Behavior, Psychology, and Informatics at Indiana University, Bloomington and an External Professor at the Santa Fe Institute. She is the co-chair of the EVOLANG conferences and the co-director of the Diverse Intelligences Summer Institute. She is co-director of the Possible Minds lab at IU, and also manages the Observing Animals project, which asks for public input on how animals interact with each other.

    9 March 2026, 12:27 pm
  • 3 hours 53 minutes
    AMA | March 2026

    Welcome to the March 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy!

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    Blog post with questions and transcript: https://www.preposterousuniverse.com/podcast/2026/03/02/ama-march-2026/

    Support Mindscape on Patreon.

    2 March 2026, 8:33 pm
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