Dr. Steven Austad is a biologist and leading expert on the evolution of aging, known for studying why different animal species age at dramatically different rates. Before entering science, he worked as a lion trainer in Hollywood.

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Timestamps:

00:00 Intro

00:25 How Dr Austad went from a lion tamer to aging research

03:20 Why animals life so different lifespans

07:25 Why natural selection selects for shorter lifespans

08:40 What limits human lifespan

12:10 Bon Charge sponsorship

13:00 Is the first person to live to 150 is already alive

17:40 How can we make humans live to 150

21:40 mTOR pathway and lifespan

25:45 Rapamycin

29:15 Is protein restriction a viable longevity strategy

33:10 Is calorie restriction a viable longevity strategy

36:08 Metformin

38:20 SGLT2 inhibitors

40:30 Are billionnaires taking extending their own lifespan seriously

43:30 Gene editing

45:15 Can common supplements extend lifespan

48:20 How to know if aging research is working

49:20 Biomarkers of aging

52:20 How AI will transform aging research

53:30 What should people prioritize to extend their lifespan

57:30 Stay up to date with Steve’s research

Dr. Steven Austad website: https://www.stevenaustad.com/

What's your Health %-ile? Take the assessment and discover exactly where you rank: https://www.skool.com/top1health

Video on my bloodwork that ranked me #1 at the Longevity World Cup https://youtu.be/2xrxXOVnLzE

P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Charles Duhigg is a Pulitzer Prize-winning journalist and bestselling author best known for The Power of Habit, which explores the science of how habits are formed and changed. His work combines psychology, neuroscience, and real-world case studies to help people build better habits, improve productivity, and create lasting behavior change.

Timestamps:

00:00 Intro

00:43 How GLP1s change habit formation

03:21 How GLP1s reduce food noise

05:18 The 3 components of every habit

08:41 Willpower versus biological mechanisms in weight loss

11:46 Bon Charge sponsorship

12:36 How eating less and being leaner makes me want to eat less food

15:26 Revealed preferences vs stated preferences

18:51 Window of self-awareness for changing habits

19:21 How to start changing habits

25:26 Building the mindfulness muscle through neuroplasticity

28:46 Role of dopamine in habits

30:56 How GLP1s influence addictions and addictive behavior

32:56 Are people who need to use GLP1s just lazy

36:31 How understanding the habit window can help you change habits

39:01 Workout plan for creating habit windows

40:41 Feeling less enjoyment after starting to use GLP1s

45:21 Future areas of research in GLP1s and habit formation

49:26 Understanding the power you have over your own life

Charles Duhigg Instagram: https://www.instagram.com/charlesduhigg/

Discover your health % and get your roadmap to Top 1% Health: https://www.skool.com/top1health/

P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:

00:00 Intro

00:45 Who is the healthiest family in Singapore

05:05 What made Tiat start his fitness program

07:15 Tiat’s test for assessing biological age and fitness

10:55 Bon Charge sponsorship

11:45 How the Lim family ranked at the Longevity World Cup

15:35 How Charlotte reached 6 pullups at age 80

20:35 The importance of fitness for longevity

24:10 Fit rx workout routine

28:45 Why Singapore has one of the highest life expectancies in the world

34:35 Nutrition habits

41:40 Supplements

51:45 Importance of making healthy food taste good

56:20 Social media usernames for everyone

58:15 What advice they wished they adopted sooner

Pullup Grandma Instagram: https://www.instagram.com/pullup_grandma/

Yan Instagram: https://www.instagram.com/coachwhy_yan/

Melody Instagram: https://www.instagram.com/melody_the_machine

Tiat Instagram: https://www.instagram.com/deaging.guru/

Discover your health % and get your roadmap to Top 1% Health: https://www.skool.com/top1health/

I tried the most popular HIIT training protocols: https://youtu.be/6Z4HikG4RFs

P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:

00:00 Intro

00:13 How to improve HRV and resting heart rate if you’re already healthy and exercising

06:03 Most optimal way to distribute protein, carbs, and fats

12:17 Bon Charge sponsorship

13:08 Thoughts on hyperbaric oxygen therapy for longevity

17:31 Best ways to mitigate 8 hours of sitting

20:30 At what age does the body start to get worse

25:30 Methionine and glycine ratio from animal protein

29:43 If you had Squamous Cell Carcinoma (skin cancer), what are some steps that you would take to mitigate its spread? Like while waiting for the removal surgery.

31:26 Electrical muscle stimulation with occlusion training for muscle hypertrophy

38:20 Best way to get rid of acne naturally

40:58 Why my Instagram got deleted

42:05 What’s something the longevity community spends way too much time worrying about

47:43 I’m 30 and all my biomarkers are in top 10% - where should I focus on next

50:55 What would I do if I got prediabetes tomorrow?

Discover your health % and get your roadmap to Top 1% Health: https://www.skool.com/top1health/

I tried the most popular HIIT training protocols: https://youtu.be/6Z4HikG4

Taken from my appearance at the Detached Podcast: https://youtu.be/aEuKyVFT93Y?si=bRtuQei0w7xo2s9N

Get The New Science of Supplements book: https://amzn.to/4ebe2Lw

Timestamps:

00:00 Intro

00:30 Top evidence-based supplements

29:55 Supplements with the worst evidence

34:25 Supplements that need more research

47:58 Conclusion

100 Supplements Ranked Tierlist Worst to Best: https://youtu.be/W8DZbYyuDmA

Start rewinding your biological clock: https://www.siimland.co/course

P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.

This is a replay of Siim Land on Chris MM Health's YouTube channel: https://www.youtube.com/watch?v=vXpES7lty2Q

Timestamps:

0:00 – Intro

0:56 – Beating Bryan Johnson In Biomarkers

4:00 – Longevity Escape Velocity Explained

4:39 – Can Humans Live To 150+ Years?

10:10 – Biological Age & Longevity World Cup

12:34 – Biological Age Of 10 Years Old?!

14:10 – Most Important Longevity Biomarkers

16:35 – VO2 Max, Visceral Fat & Fitness

19:28 – Pull-Ups, Strength & Longevity

22:44 – Inflammation, hs-CRP & Aging

24:12 – HbA1c, Insulin & Triglycerides

31:01 – Body Fat, Exercise & Mortality Risk

40:44 – SIIM LAND’s Diet & Whole Foods

46:24 – Why Perfect Health Is Not Enough

51:20 – Supplements: Glycine, Omega-3 & More

Dr. Michael Snyder is a genomicist, professor, and former chair of genetics at Stanford University School of Medicine. He is the Director of the Center for Genomics and Personalized Medicine at Stanford University and a pioneer in precision medicine and multi-omic profiling.

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:

00:00 Intro

00:26 Dr. Snyder’s paper that changes the way we look at aging

05:46 Why aging accelerates after 44 and 60

09:31 What’s good for young people might not be good for someone who’s old

12:10 Metabolic changes that happen during aging

15:57 How big of a role does genetics play in longevity

21:57 What’s going to extend lifespan more: genetic engineering or lifestyle interventions

27:37 What is Multi-omics

31:10 Continuous glucose monitoring

35:10 Different types of glucose spikers

38:40 HRV tracking

42:00 How collecting more data can predict your health risks

47:48 Is tracking health preemptively bad

52:25 What people should track about their health

57:00 How the retina reflect systemic health risks

59:45 Biological age clocks

Dr. Michael Snyder's lab website: https://med.stanford.edu/snyderlab/about.htmlStart rewinding your biological clock: https://www.siimland.co/course

Siim Land returns as the current leader of the Longevity World Cup, to break down supplements, biomarkers, VO2 max, inflammation, sleep, and the difference between building health versus simply maintaining it.

Watch on YouTube: https://www.youtube.com/watch?v=ogy7l0nka-Y

Dr. Alexis Ortega is board-certified in longevity, regenerative and aesthetic medicine. He has a clinic Ad Astra in Barcelona, Spain.

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:

00:00 Intro

00:55 How to counteract age-related loss of facial harmony aside from just wrinkles

12:30 Does growth hormone change the face

18:10 Bon Charge sponsorship

19:17 What's the minimum effective dose of at-home skincare — the three things that actually move the needle?

21:28 Retinoids

24:05 Skin barrier support

27:00 Effect of sun exposure on extrinsic skin aging

31:02 Best evidence-based sunscreen ingredients

34:34 List of best sunscreen ingredients

36:00 Worst sunscreen ingredients

37:45 Daily sunscreen vs using the UV index as a guide

39:43 Do people overuse skincare products

42:33 Castor oil, beef tallow and egg yolks for skin

49:08 Are natural sunscreens effective

49:59 If someone had unlimited money today, what are the most promising rejuvenation interventions actually available?

51:08 What diagnostics Alexis would do with an unlimited budget

54:30 Rejuvenation therapies Alexis would do

55:18 Alexis approach to peptides

56:00 Intravenous senolytics

56:20 NAD injections

57:14 What you can do now to practically extend lifespan

59:40 Intravenous exosomes

01:00:25 Therapeutic plasma exchange

01:03:06 Stem cell therapy

01:05:30 Gene therapies

01:07:48 What biomarkers matter most for predicting long-term health

Alexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/

Dr. Kevin Perez is a computational biologist working at the cutting edge of aging science and drug discovery. His work focuses on aging research, drug repurposing, and integrating complex multi-omics data to better understand how we can extend healthspan.

Check out Bon Charge wellness products (Code SIIM for 15% discount): https://boncharge.com/siimland

Timestamps:

00:00 Intro

00:47 Kevin’s study about pharmaceuticals that are associated with reduced mortality

10:17 Which class of drugs had reduced mortality

13:07 Bon Charge sponsorship

14:12 How Kevin researches longevity molecules

16:37 Estrogen’s longevity effects

17:37 How Kevin started researching dog aging

25:32 Chemical reprogramming

29:32 Kevin’s understanding of what causes aging

34:52 Metformin vs SGLT2 inhibitors

38:37 Erectile dysfunction drugs

43:02 Over the counter supplements with longevity effects

45:52 Biological age clocks

50:02 What Kevin thinks is the best biomarker of aging

54:32 Composite biological age vs combination of multiple markers

59:32 Kevin’s new study plans

01:02:52 What Kevin wishes he adopted sooner

Start rewinding your biological clock: https://www.siimland.co/course

P.S. This is not professional medical advice and should not be taken as such. The creator of this video is not held accountable for your health. Consult your doctor first.