• 31 minutes 26 seconds
    Psilocybin Mushrooms: Strains, Potency, and Experience - Paul F. Austin

    In this solo episode of The Psychedelic Podcast, Paul F. Austin explores one of the most common questions in the psychedelic space: which psilocybin mushroom strain is actually best?

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-360/?ref=278

    Moving beyond the search for the "strongest" mushroom, Paul breaks down the factors that truly shape a meaningful experience, including strain selection, potency, preparation methods, storage practices, individual sensitivity, and the critical role of context.

    Drawing on years of experience through Third Wave and the Psychedelic Coaching Institute, Paul compares popular strains such as Golden Teacher, Penis Envy, Ghost, Enigma, and Psilocybe natalensis. He also explains why preparation methods like lemon tekking matter, how to think about microdosing versus macrodosing, and why integration remains one of the most important variables in long-term outcomes.

    Paul F. Austin is an entrepreneur, educator, and pioneer in the psychedelic field. He is the founder of Third Wave, a leading platform dedicated to psychedelic education, and the Psychedelic Coaching Institute, which trains coaches and practitioners to responsibly support psychedelic experiences and integration. As the host of The Psychedelic Podcast, Paul has interviewed hundreds of leading researchers, clinicians, indigenous wisdom keepers, entrepreneurs, and cultural innovators at the forefront of the psychedelic renaissance.

    Highlights:

    • Why stronger isn't always better
    • The myth of the strongest strain
    • Golden Teacher vs. Penis Envy
    • Understanding Ghost and Enigma
    • Psilocybe natalensis explained
    • How lemon tek changes the journey
    • Why storage affects potency
    • Microdosing vs. macrodosing
    • Context shapes psychedelic outcomes
    • Integration beyond the peak experience

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    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    15 June 2026, 8:00 am
  • 46 minutes 21 seconds
    Choosing the Right Microdose: Psilocybin, LSD, Huachuma & More - Paul F. Austin

    In this special solo episode, adapted from a recent live training, Paul F. Austin explores one of the most important and often overlooked realities of microdosing: different substances create different outcomes.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-359/?ref=278

    Drawing on more than a decade of experience in psychedelic education and coaching, Paul compares psilocybin, LSD, huachuma (San Pedro), ketamine, and iboga through the lens of client goals, nervous system regulation, emotional processing, cognitive performance, and contraindications.

    Paul explains why generic microdosing protocols often fall short, how practitioners can better match substances to individual needs, and why context, preparation, and integration matter far more than any single medicine. He also shares why huachuma has become the foundation of the Psychedelic Coaching Institute's microdosing methodology and offers guidance for practitioners looking to support clients with greater precision and care.

    Highlights:

    • Why generic microdosing protocols can fall short
    • How psilocybin supports emotional processing and inner work
    • LSD's role in focus, creativity, and physiological performance
    • Why huachuma may be especially useful for nervous system regulation
    • Ketamine's role in SSRI tapering and clinical support
    • Iboga's potential for neurodegenerative conditions and brain injury
    • How to match substances to a client's goals and baseline state
    • Why contraindications and clinical-grade intake matter
    • How microdosing can support post-journey integration
    • Why "more medicine" is not always the answer

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    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    8 June 2026, 8:00 am
  • 59 minutes 35 seconds
    Amazonian Tobacco Medicine: Dieta, Ceremony, and Lineage - Jason Grechanik

    In this episode of The Psychedelic Podcast, Paul F. Austin welcomes Jason Grechanik, master tabaquero and host of The Universe Within Podcast, for a deep exploration of sacred tobacco as Amazonian plant medicine.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-358/?ref=278

    Sacred tobacco is usually understood in the West through the lens of cigarettes, addiction, and commercial misuse. But in Amazonian traditions, Nicotiana rustica is understood very differently: as a master plant, a protector, and a powerful medicine that requires lineage, discernment, and right relationship.

    Drawing from nearly a decade of Amazonian immersion and more than 1,000 people guided through plant ceremonies, Jason shares how tobacco is worked with in dieta, ayahuasca ceremony, energetic protection, and direct relationship with plant spirits. Paul and Jason also discuss cannabis, indigenous cosmologies, safety, and what tobacco's history can teach the modern psychedelic movement about power, humility, and proper containers.

    Jason Grechanik is a master tabaquero trained in the Mamankunawa tradition under curandero Don Ernesto Garcia Torres. With nearly a decade of Amazonian immersion and more than 1,000 people guided through plant ceremonies, Jason spent many years at the renowned Shipibo healing center Temple of the Way of Light. He is the host of The Universe Within Podcast, with 180+ episodes and 20K+ monthly listeners, co-founder of the Nicotiana Rustica project, and has been featured in DoubleBlind Magazine.

    Highlights:

    • Jason's path into Amazonian tobacco medicine
    • Tobacco beyond commercial cigarettes
    • Why tobacco is considered a master plant
    • Dieta as direct plant relationship
    • Tobacco as portal and protector
    • Ayahuasca, diagnosis, and plant doctors
    • Safety, toxicity, and proper containers
    • Jaguar and hummingbird tobacco archetypes
    • Cannabis, dreams, and plant relationship
    • Lessons for the psychedelic renaissance

    Episode Links:

    Episode Sponsors:

    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    1 June 2026, 8:00 am
  • 55 minutes 33 seconds
    Ketamine for Couples: Transforming Relational Patterns - Chandra Estelle Khalifian, Ph.D

    In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Chandra Estelle Khalifian, a clinical psychologist, relationship researcher, and co-founder of Enamory, about the intersection of attachment science, couples therapy, and psychedelic-assisted healing.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-357/?ref=278

    Drawing from her work in ketamine-assisted couple therapy and MDMA research, Chandra explores how relationships are shaped by nervous system regulation, attachment wounds, and patterns developed long before adulthood.

    The conversation examines how ketamine and MDMA can help couples move through rigidity, betrayal, grief, and disconnection by creating greater emotional openness and flexibility. Paul and Chandra also dive into conscious uncoupling, relational growth, community, and the deeper distinction between love as a feeling versus love as a practice.

    Chandra Khalifian, Ph.D. is a clinical psychologist, researcher, and educator specializing in psychedelic-assisted couple therapy. She co-founded Enamory, alongside Dr. Kayla Knopp, a private practice clinic, training institute, and research foundation based in San Diego, California. Their work focuses on ketamine-assisted couple therapy, including clinical data collection and therapist training programs designed to support practitioners integrating psychedelic-assisted couple therapy into their practices. Chandra's work bridges attachment science, nervous system regulation, relationship psychology, and psychedelic medicine.

    Highlights:

    • How Attachment Shapes Adult Relationships
    • Ketamine for Breaking Relational Rigidity
    • Why Secure Attachment Feels Safe
    • MDMA for Betrayal & Repair
    • Conscious Uncoupling Without Hatred
    • Why Love Alone Isn't Enough
    • Healing Grief Through Psychedelic Therapy
    • Couples Therapy as Nervous System Work

    Episode Links:

    Episode Sponsors:

    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    25 May 2026, 8:00 am
  • 55 minutes 54 seconds
    Why Group Psychedelic Therapy Matters - Dr. Lauren Macdonald

    In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Lauren Macdonald, a clinical trial physician and psychedelic therapist, about the evolving role of community in psychedelic-assisted therapy.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-356/?ref=278

    Lauren shares insights from her work at Imperial College London, where she contributed to research on psilocybin for anorexia and fibromyalgia, as well as DMT for treatment-resistant depression. She reflects on the limitations of purely individual therapeutic models and explores how group-based approaches can foster deeper healing through connection, shared experience, and what she describes as communitas.

    The conversation also touches on the contrast between clinical and ceremonial settings, the role of group dynamics in emotional processing, and the challenges of access and affordability as psychedelic therapy expands.

    Dr. Lauren Macdonald has a background in psychiatry, psychedelic-assisted therapy, and group retreat facilitation, working at the intersection of science, soul, and spirit. At the Centre for Psychedelic Research at Imperial College London, she has served as a clinical trial doctor and psychedelic therapist on studies exploring psilocybin for anorexia and fibromyalgia, and DMT for treatment-resistant depression.

    Highlights:

    • Psilocybin therapy in clinical research
    • Limits of individual therapy models
    • Why group work deepens healing
    • Communitas and shared experience
    • Bridging science and spirituality
    • Psychedelics in palliative care
    • Relational safety in altered states

    Episode Links:

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    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    18 May 2026, 8:00 am
  • 54 minutes 5 seconds
    Psychedelics and Myth: Why Story Shapes Transformation - David Adam Burns

    In this episode of The Psychedelic Podcast, Paul F. Austin speaks with David Adam Burns, a transformational coach, artist, and founder of The Mysteries, about what may be missing from today's psychedelic conversation.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-355/?ref=278

    David challenges the emphasis on insight in psychedelic work, suggesting that deeper transformation comes through presence, healing, and embodied evolution. He outlines a framework for healing through integration, purification, and emotional "thawing," and explains why presence may be the most important skill for navigating psychedelic experiences.

    They also explore myth and storytelling as tools for collective growth, including David's work with The Mysteries and Earthsong, a retelling of the Persephone myth, and discuss the role of community, leadership, and stewardship in shaping the future of psychedelics.

    David Adam Burns is a transformational coach, artist, and facilitator devoted to helping human beings remember who they are. Since 2015, he has guided leaders through deep personal transformation in his one-on-one practice and co-founded The Mysteries, an artists' collective dedicated to expressing the ineffable through myth and performance.

    Highlights:

    • Why insight is often overvalued
    • Healing as integration, purification, and thawing
    • Presence as the core psychedelic skill
    • Story and myth as collective technologies
    • The role of community in transformation
    • Why leadership determines long-term outcomes

    Episode Links:

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    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    11 May 2026, 8:00 am
  • 54 minutes 49 seconds
    IFS & Psychedelics: A Guide for Practitioners - Heather Smith

    In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Heather Smith, founder of The Moxie School and a certified Internal Family Systems (IFS) therapist, about the intersection of parts work and psychedelic healing.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-354/?ref=278

    Heather explains how IFS offers a practical framework for working with what arises during psychedelic experiences. She describes IFS as an approach that helps people stay present with different parts of themselves, especially when difficult or unexpected material comes up.

    The conversation explores how psychedelic experiences can bring awareness to underlying patterns and past experiences, and why that awareness on its own often doesn't lead to lasting change.

    They also discuss common misconceptions about combining IFS with psychedelics, the role of preparation and integration, and how working directly with parts supports more stable change over time.

    Highlights:

    • Misconceptions about IFS in psychedelic work
    • IFS as a mindset, not a method
    • How psychedelics reveal internal parts
    • Why insight alone isn't enough
    • The unburdening process in healing
    • Working with fear and difficult experiences
    • Preparation and integration as core skills
    • Practitioner integrity and embodied practice

    Heather Smith is a visionary in the field of psychedelic healing, blending Internal Family Systems (IFS) therapy with expanded states of consciousness to catalyze deep transformation. A Certified IFS therapist, she has completed Levels 1–3 of training and served as a Program Assistant multiple times.

    She is the founder of The Moxie School®, where she trains psychedelic facilitators in IFS-informed approaches and supports both personal and professional development through immersive training and retreat experiences.

    Episode Links:

    Episode Sponsors:

    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    4 May 2026, 8:00 am
  • 56 minutes 46 seconds
    Right to Try Psilocybin: Law, Death, and Dignity - Kathryn L. Tucker, J.D.

    In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Kathryn L. Tucker, J.D., a leading civil rights attorney and advocate for end-of-life autonomy, about the legal effort to expand access to psilocybin-assisted therapy for patients facing serious illness.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-353/?ref=278

    Kathryn shares how decades of work in right-to-die litigation led her to recognize a critical gap in palliative care, addressing psychological and existential suffering at the end of life. Drawing from emerging clinical research, she explains why psilocybin may offer meaningful relief for anxiety, depression, and distress in terminal patients.

    The conversation explores the legal pathways being pursued to make this treatment accessible, including Right to Try laws, federal litigation with the DEA, and efforts to reschedule psilocybin. Kathryn also reflects on the broader cultural and ethical implications of allowing individuals greater choice in how they approach death.

    Kathryn L. Tucker, JD, is a nationally recognized leader in advancing improved care for seriously ill and dying patients. She has held leadership roles across multiple nonprofit organizations, including the National Psychedelics Association, the End of Life Liberty Project, and Compassion & Choices. Tucker has litigated landmark cases before the U.S. Supreme Court, including Washington v. Glucksberg and Vacco v. Quill, and has played a key role in both end-of-life litigation and psychedelic policy advocacy.

    Highlights:

    • Right to Try laws explained
    • Psilocybin as investigational medicine
    • DEA barriers to patient access
    • Litigation strategies for psychedelic access
    • Rescheduling psilocybin efforts
    • Palliative care gaps in mental suffering
    • Legal vs underground psychedelic

    Episode Links:

    Episode Sponsors:

    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    27 April 2026, 8:00 am
  • 55 minutes 15 seconds
    Healing Before Leading: Psychedelics and Political Integrity - Laura Dunn

    Healing Before Leading: Psychedelics and Political Integrity

    In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Laura Dunn, civil rights attorney and congressional candidate, about trauma, leadership, and the role of psychedelic healing.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-352/?ref=278

    Laura shares how her work advocating for survivors led her to confront the deeper limitations of legal and institutional systems. While policy change can create meaningful protections, it often fails to address the underlying trauma individuals carry.

    They explore how psychedelic experiences became part of her personal healing journey, and how that informs her approach to leadership, public service, and political integrity.

    Laura Dunn is an award-winning civil rights attorney, former public school teacher, and congressional candidate in New York's 12th District. She helped shape Title IX protections, contributed to the Violence Against Women Act reauthorization, and founded SurvJustice, a nonprofit supporting survivors of sexual violence. Her work bridges advocacy, policy, and trauma-informed leadership.

    Highlights:

    • From survivor advocacy to policy reform
    • Limits of legal systems in trauma healing
    • Why leadership requires inner work
    • Psychedelics as tools for self-awareness
    • Breaking stigma in political leadership
    • Bipartisan support for reform
    • Veterans and policy momentum
    • Trauma and leadership integrity
    • A vision for conscious governance

    Episode Links:

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    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    20 April 2026, 8:00 am
  • 1 hour 2 minutes
    Western Philosophy on Drugs: Consciousness, Dreams, and Reality - Justin Smith-Ruiu

    Western Philosophy on Drugs: Consciousness, Dreams, and Reality

    In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Dr. Justin Smith-Ruiu about how psychedelic experiences challenge long-standing assumptions about consciousness, perception, and reality.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-351/?ref=278

    Justin explains how Western philosophy has historically privileged rational, sober, and waking states of mind, often dismissing dreams and altered states as unreliable. He explores how psychedelic experiences push against these assumptions, raising deeper questions about knowledge, language, and what counts as real.

    The conversation also examines the tension between therapeutic and existential uses of psychedelics, and how medicalization may shape the cultural role these substances play moving forward.

    Justin Smith-Ruiu is a professor of history and philosophy of science at the Université Paris Cité and author of On Drugs: Psychedelics, Philosophy, and the Nature of Reality. His work explores intellectual history, consciousness, and the limits of rational thought, and he writes regularly for Harper's, WIRED, and The New York Times.

    Highlights:

    • How philosophy excludes altered states
    • Why dreams are dismissed as unreliable
    • Psychedelics and limits of rationality
    • Language and ineffability of experience
    • Therapeutic vs existential frameworks
    • Medicalization and cultural impact
    • Philosophy beyond sober cognition

    Episode Links:

    Episode Sponsors:

    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    13 April 2026, 8:00 am
  • 1 hour 8 minutes
    Can Ketamine Help Benzodiazepine Withdrawal? - Melissa Bond & Dr. Amy de la Garza

    Can Ketamine Help Benzodiazepine Withdrawal? - Melissa Bond & Dr. Amy de la Garza

    In this episode of The Psychedelic Podcast, Paul F. Austin speaks with Melissa Bond and Dr. Amy de la Garza about the hidden risks of benzodiazepines, the reality of dependency, and what recovery can require.

    Find full show notes and links here: https://thethirdwave.co/podcast/episode-350/?ref=278

    Melissa shares her experience of becoming dependent on prescribed medication, and the physical and emotional challenges of withdrawal. Dr. de la Garza brings a clinical perspective, explaining how benzodiazepines affect the nervous system and why withdrawal can be prolonged and destabilizing.

    The conversation also looks at where conventional care often falls short, and how more integrative approaches are beginning to emerge. This includes the use of low-dose ketamine as a potential tool to support the nervous system during withdrawal, particularly in more complex or prolonged cases.

    Melissa Bond is a narrative journalist and poet. Her memoir Blood Orange Night, which chronicles her experience with benzodiazepine dependency, was published by Simon & Schuster and recognized by The New York Times as one of the best audiobooks of 2022. Her work has appeared on PBS, The New York Times Podcast, RadioWest, and TEDx. Dr. Amy de la Garza is a board-certified physician in Family and Addiction Medicine, a certified Functional Medicine practitioner, and co-founder of Nosis Health, a virtual outpatient addiction medicine platform. Her work integrates functional, lifestyle, and emerging therapies, including ketamine-assisted treatment, to support recovery.

    Highlights:

    • Melissa Bond's experience with benzodiazepine dependency and withdrawal
    • How prescribed use can gradually lead to physical dependence
    • Why benzodiazepine withdrawal can be prolonged and destabilizing
    • The neurological effects of benzodiazepines on the nervous system
    • Gaps in conventional approaches to anxiety and addiction treatment
    • The role of functional and lifestyle medicine in recovery
    • How low-dose ketamine is being explored to support withdrawal
    • What a more integrative, whole-person model of care can look like

    Episode Links:

    Episode Sponsors:

    Disclaimer: This content is for educational, informational, and entertainment purposes only. We do not promote or encourage the illegal use of any controlled substances. Nothing said here is medical or legal advice. Always consult a qualified medical or mental health professional before making decisions related to your health. The views expressed herein belong to the speaker alone, and do not reflect the views of any other person, company, or organization.

    Third Wave occasionally partners with or shares information about other people, companies, and/or providers. While we work hard to only share information about ethical and responsible third parties, we can't and don't control the behavior of, products and services offered by, or the statements made by people, companies, or providers other than Third Wave. Accordingly, we encourage you to research for yourself, and consult a medical, legal, or financial professional before making decisions in those areas. Third Wave isn't responsible for the statements, conduct, services, or products of third parties. If we share a coupon code, we may receive a commission from sales arising from customers who use our coupon code. No one is required to use our coupon codes.

    6 April 2026, 8:00 am
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