Metabolic Health, Advanced Lipidology, and Preventing ASCVD

Level up your primary prevention game. Learn when ApoB, Lp(a), and CAC actually change management, how to spot cardiometabolic risk before diabetes declares itself, and how to make smarter lipid decisions beyond the standard panel. We’re joined by Dr. Greg Katz, cardiologist and prevention expert at NYU Langone Health.

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

• Intro
• Primary Prevention & Metabolic Syndrome (Case 1)
• Beyond the Standard Lipid Panel
• When to Order ApoB
• How Lp(a) Changes Management (Case 2)
• Using CAC/CCTA in the Gray Zone
• Recognizing Early Cardiometabolic Risk
• CGMs, Wearables, and Signal vs Noise (Case 3)
• How to Talk to Patients About Risk
• Take-Home Points

Credits

Written and produced by Paul Wurtz MD. Show notes, cover art, and infographic also created by Paul Wurtz MD.

• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
• Reviewer: Sai S Achi MD, MBA, FACP
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Greg Katz MD

Disclosures

Dr. Katz reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. 

Sponsor: DeleteMe

Get 20% off your DeleteMe plan when you go to joindeleteme.com/CURB and use promo
code CURB at checkout.

Sponsor: Panacea Legal 

Visit Panacea.Legal  and use code CURB20 for 20% off contract review services.

Sponsor: FIGS

We’ve teamed up with FIGS, and now Curbsiders listeners can get 15% off. Just go to and use code FIGSRX. 

Sponsor: Continuing Education Company

For Curbsiders listeners, there’s a special offer: use promo code Curb30 for 30% off all online courses and webcasts. Visit CMEmeeting.org/curbsiders to learn more.  

Join us as we review and appraise recent practice-changing articles. In this episode, we cover the latest in GLP-1s and GIP agonists for CVD, Type 2 Diabetes, and Obesity, valacyclovir to treat Alzheimer’s, weight regain patterns after medication-induced weight loss, and a deep dive into the data behind deprescribing – and behavioral science to increase deprescribing behavior.  Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Alex Chaitoff (@alexchaitoff), Nora Taranto (@norataranto), & Matt Watto (@doctorwatto).

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Credits

• Written and Hosted by: Nora Taranto MD, MSCE; Alexander Chaitoff MD, MPH; Paul Williams, MD, FACP,, & Matthew Watto MD, FACP
• Cover Art: Nora Taranto MD, MSCE
• Reviewer: Sai S Achi MD, MBA, FACP
• Technical Production: Pod Paste
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

• Intro, disclaimer
• GLP-1 + GIPs vs GLP-1s for patients with T2DM and Obesity – SURPASS-CVOT 
• Weight Regain after Weight loss 
• VALAD – Valacyclovir in patients with early Alzheimer’s 
• Nudges to increase Deprescribing 
• Outro

Sponsor: MedStudy Qbank 

Study less. Remember more. Pass confidently.
Medstudy.com/Curbsiders
CURB15 for 15% off

Sponsor: FIGS

We’ve teamed up with FIGS, and now Curbsiders listeners can get 15% off at with code FIGSRX. 

Sponsor: Quince

Right now, go to Quince.com/curb for free shipping and 365-day returns. 

Sponsor: A Dangerous Diagnosis

To get 20% off use DIAGNOSIS20 at www.penguinrandomhouse.com/books/808848/a-dangerous-diagnosis-by-shantanu-rai/paperback/

We have a classic episode for you. Conquer prediabetes and diabetes prevention! We’re joined by Dr. Scott Isaacs, who provides essential pearls on navigating  screening tests for diabetes and prediabetes, identifying atypical cases of prediabetes, and individualizing management of prediabetes with lifestyle changes and medications.

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

• Intro
• Case from Kashlak
• Why screen for prediabetes and diabetes?
• Who to screen for prediabetes and diabetes
• How to screen for prediabetes and diabetes
• Role of the physical exam
• Explaining a diagnosis of prediabetes to patients
• Atypical types of prediabetes
• Management of prediabetes: lifestyle changes
• Management of prediabetes: medications
• Outro

• Producer, Writer, and Show Notes: Malini Gandhi MD
• Infographic and Cover Art: Zoya Surani
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
• Reviewer: Sai Achi MD,MBA,FACP
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Scott Isaacs MD

Disclosures

Dr. Isaacs reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. 

Sponsor: Babbel
Get up to 60% off at Babbel.com/CURB. 

Sponsor: MedStudy Qbank
Study less. Remember more. Pass confidently. 

Medstudy.com/Curbsiders 

CURB15 for 15% off

Sponsor: University of Pennsylvania Graduate School of Education
Learn about our Medical Education master’s program, explore our certificate option, and sign up for an application fee waiver code. Take the next step in advancing medical education—visit www.gse.upenn.edu/curbsiders.

Sponsor: Locumstory
Whether you’re simply curious or seriously considering a change, pop by Locumstory.com to see if it’s something that makes sense for you

Stop getting TICK’ed off by Lyme

Master Lyme disease — from recognizing erythema migrans and avoiding unnecessary testing to managing disseminated Lyme and post-exposure prophylaxis. Learn practical, evidence-based strategies you can use in the clinic. We’re joined by Dr. Sophie Woolston MD, infectious diseases expert and clinician-educator. (MaineHealth)

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

• Intro
• Case 1
• Lyme Basics
• Stages of Lyme
• Lyme Testing and Interpretation
• Coinfection
• Lyme Treatment
• Tick Prevention and Removal
• Post-Treatment Lyme Disease Syndrome
• Outro

• Written and Produced by: Beth Gasperlin MD
• Show Notes, Infographics, and Cover Art by: Zoya Surani
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP, Beth Gasperlin MD  
• Reviewer: Leah Witt MD
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Sophie Woolston MD

Disclosures

Dr. Woolston reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. 

Sponsor: Continuing Education Company

For Curbsiders listeners, there’s a special offer: use promo code Curb30 for 30% off all online courses and webcasts.  Visit CMEmeeting.org/curbsiders to learn more.  

Sponsor: Mint Mobile

Shop plans at .

Sponsor: FIGS

We’ve teamed up with FIGS, and now Curbsiders listeners can get 15% off. Just go to WearFIGS.com and use code FIGSRX.

Sponsor: Freed

Use code FREED50 for fifty dollars off your first month at

Helping you diagnose a common cause of hypertension!

Hypertension is a growing disease globally, affecting millions of individuals and increasing the risk of heart disease and stroke. Along with the expert help of Dr. Vaidya (Brigham and Women’s Hospital), we help reimagine the approach of clinicians in terms of hypertension and help them navigate common diagnostic dilemmas! @AnandVaidya17 (Bluesky) @AnandVaidya17 (X)

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME


Show Segments

• Introduction and Personal Interests
• Advice and Wisdom in Medicine 
• Case 1
• Defining Primary Aldosteronism
• Screening for Primary Aldosteronism
• How common is Primary Aldosteronism
• Challenges in Diagnosis and Testing
• Medication Management and Testing Protocols
• Managing indeterminate cases
• Aldosterone Suppression Testing and its role
• Discussing treatment options with patients
• Case 2
• Considering genetic causes of Primary Aldosteronism
• The need for AVS for lateralization
• Upcoming imaging modalities for Primary Aldosteronism
• Case 3
• Medical Management of Primary Aldosteronism
• Future Directions in Treatment

• Producer, Writer, Show Notes:Mobeen Ahmad MBBS 
• Infographic:Kate Grant MBChB MRCGP
• Cover Art:Kate Grant MBChB MRCGP
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
• Reviewer: Emi Okamoto MD
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest:  Anand Vaidya MD, MMSc

Disclosures

Dr. Vaidya has disclosed the following: 

Financial Relationships: Astra Zeneca-Consulting Fee and Corcept-Consulting Fee, relationships have not ended. 

The Curbsiders report no relevant financial disclosures.

Sponsor: The Sanford Guide

Curbsiders listeners can get 20% off the already very moderately priced yearly subscriptions directly at sanfordguide.com. Go to sanfordguide.com and use the code, CURB at checkout.

Sponsor: MedStudy Podcast

MedStudy Qbank - Study less. Remember more. Pass confidently. Medstudy.com/Curbsiders CURB15 for 15% off

Sponsor: Panacea Legal 

Visit Panacea.Legal and use code CURB20 for 20% off contract review services.

Sponsor: DeleteMe

Get 20% off your DeleteMe plan when you go to joindeleteme.com/CURB and use promo code CURB at checkout.

Join us as we review and appraise recent practice-changing articles on oral semaglutide for obesity, fish oil in ESRD, IV iron during infection, the new US Dietary Guidelines, & anticoagulation after ablation in AFib. Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Rahul Ganatra (@rbganatra), Josh Gilman, & Matt Watto (@doctorwatto).

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Credits

• Written and Hosted by: Rahul Ganatra MD, MPH; Paul Williams, MD, FACP, Joshua Gilman, MD, & Matthew Watto MD, FACP
• Cover Art: Rahul Ganatra, MD MPH
• Reviewer: Emi Okamoto, MD
• Technical Production: Pod Paste
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP

• Intro, disclaimer
• Oral Semaglutide for obesity
• Fish Oil for CV risk reduction in hemodialysis patients
• IV Iron for iron deficiency anemia during infection
• New USA Dietary Guidelines
• Anticoagulation after catheter ablation for AF
• Outro

Sponsor: FIGS

Check out the limited-edition Team USA collection, and get 15 percent off your first order at with code FIGSRX. 

Sponsor: Continuing Education Company

Visit CMEmeeting.org/curbsiders and use promo code Curb30 for 30% off all online courses and webcasts.  

Sponsor: Gusto

Try Gusto today at gusto.com/CURB, and get three months free when you run your first payroll.

Sponsor: MDProgress 

For our listeners, enjoy your first month free at mdprogress.ca/promo/curbsiders

We have another classic episode for you. Master inpatient heart failure management! Learn key tips for initiating guideline-directed medical therapy, diuretic therapy pearls, and ensuring smooth transitions of care. We are joined by Dr. Gurusher Panjrath @PanjrathG (GW School of Medicine and Health Sciences-Dr. Panjrath)

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

• Intro
• Rapid Fire Questions/Picks of the Week
• Case Aliquot 1
• Defining Heart Failure
• POCUS in Heart Failure
• Timing/Indications for Echocardiography
• Initiating Diuretic Therapy
• Adjusting Diuretic Therapy/Drip vs Bolus
• Adjunct Diuretic Therapy
• Afterload Reduction
• Monitoring Diuretic Response
• Inpatient Sodium and Fluid Restriction
• Case Aliquot 2
• Classifying Heart Failure
• Pharmacotherapy for HFrEF
• Pharmacotherapy for HFpEF
• Ischemic Evaluation
• Interval Summary/Highlights
• Case Aliquot 3
• Considerations for Initial Care of Cardiogenic Shock
• Choosing Inotrope/Vasopressor
• Right Heart Catheterization
• Case Aliquot 4
• Discharge Medications for Heart Failure
• Titration of Goal Directed Medical Therapy
• Post Discharge Follow Up
• Washout Period for ACEi/ARB
• Cost/Barriers of ARNI
• Patient Education
• Take Home Points
• Outro

• Writer, Producer, and Show Notes by: Reaford Blackburn, Jr., MD
• Infographic & Cover Art: Caroline Coleman MD
• Hosts: Monee Amin, MD and Meredith Trubitt, MD   
• Reviewer: Rahul Ganatra MD
• Technical Production: PodPaste
• Guest: Gurusher Panjrath, MD

Sponsor: MDProgress

Enjoy your first month free at mdprogress.ca/promo/curbsiders

Sponsor: Quince

Go to Quince.com/curb for free shipping on your order and 365-day returns. Now available in Canada, too.

Sponsor: Sanford Guide 

Curbsiders listeners can get 20% off the already very moderately priced yearly subscriptions directly at sanfordguide.com.

Sponsor: Babbel  

Here's a special, (limited time) deal for our listeners. Right now get up to 55% off your Babbel subscription – at Babbel.com/CURB.

Dr. Fleseriu schools us on managing the unexpected

Become a master of pituitary incidentalomas. Learn about the hormonal workup and management of pituitary microadenomas, macroadenomas and empty sella syndrome and when surgery may be needed. We’re joined by Dr. Maria Fleseriu, @MariaFleseriu (Oregon Health and Science University)

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

• Intro
• Rapid fire questions/Picks of the Week
• Case 1
• Defining Pituitary Incidentalomas
• What is the difference between micro adenoma, macroadenoma and functional vs non-functional adenomas
• Hormonal workup of microadenoma (assessing for hypopituitarism and hormonal excess)
• Decided when to reimage patients and long term follow up of microadenomas
• Case 2
• Hormonal workup for pituitary macroadenoma
• Deciding when surgery should be considered
• Discussing the role of visual field testing
• Case 3
• Defining empty sella syndrome
• Discussing hormonal assessment of empty sella syndrome
• Treatment options for hyperprolactinemia caused by empty sella syndrome
• Outro

• Producer, writer, show notes, and CME: Mobeen Ahmad MD
• Infographic and cover art: Kate Grant MBChb, MRCGP
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
• Reviewer: Emi Okamoto MD
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Dr. Maria Fleseriu

Disclosures

Dr. Fleseriu reports no relevant financial disclosures. The Curbsiders report no relevant financial disclosures. 

Sponsor: Continuing Education Company

Curbsiders listeners, there’s a special offer: use promo code Curb30 for 30% off all online courses and webcasts. Visit CMEmeeting.org/curbsiders to learn more.

Sponsor: Mint Mobile

New customers can make the switch today and for a limited time, get unlimited premium wireless for just $15 per month. Switch now at mintmobile.com/CURB

Sponsor: Locumstory

Locumstory.com is literally just a free, unbiased resource dedicated to educating physicians about locums.

Sponsor: FIGS

Check out the limited-edition Team USA collection, and get 15 percent off your first order at with code FIGSRX. 

We have a classic episode for you. Master male hypogonadism diagnosis and management. Discover when and how to test, how to tackle confounding conditions, and why lifestyle changes may be more effective than testosterone therapy in certain patients. We are joined by Dr. Brad Anawalt, an expert in endocrine care, to guide us through the essentials.

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME


Show Segments

• Intro
• Case 1
• History and Physical 
• Laboratory Testing 
• Effect of Lifestyle on Testosterone
• Case 2
• Prostate and Cardiovascular risk
• Treatment Options and Considerations
• Secondary Causes of Hypogonadism
• Case 3
• Testicular Size and Klinefelter Syndrome
• hCG and Clomiphene
• Monitoring and Follow-Up
• Take-Home Points
• Outro

• Written and produced by Paul Wurtz MD. Show notes, cover art, and infographic also created by Paul Wurtz MD. 
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
• Reviewer: Sai S Achi MD, MBA, FACP
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Bradley D. Anawalt MD

Sponsor: Gusto

Try Gusto today at , and get three months free when you run your first payroll.

Sponsor: Locumstory

Locumstory.com is literally just a free, unbiased resource dedicated to educating physicians about locums. 

Sponsor: The Sanford Guide

Curbsiders listeners can get 20% off the already very moderately priced yearly subscriptions directly at sanfordguide.com. Go to sanfordguide.com and use the code, CURB at checkout.

What Dreams May Come

Breeze through your next visit for insomnia. Learn how to comfortably approach insomnia and optimize sleep. We touch on specifics such as cognitive behavioral therapy for insomnia or the effects of various sleep-related drugs/supplements, and how to taper down from them. We are joined by Ashley E. Mason, PhD (UCSF).

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

• Intro
• Case
• Understanding patient’s goals
• Cognitive behavioral therapy for insomnia
• Stimulus control
• Sleep Hygiene
• Time-in-bed restriction
• Impact of different medications/substances on sleep
• Tapering off medications
• Outro

• Producer and Writer: Matthew Watto MD, FACP
• Producer, Show Notes, Infographic, and Cover art: Edison Jyang, MD
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
• Reviewer: Sai S Achi, MD, MBA, FACP
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Ashley E. Mason, PhD

Disclosures

Dr. Mason has disclosed the following:
Financial Relationships: Evolve Global, consulting fee and stock options; Oura Health, consulting fee.

The Curbsiders report no relevant financial disclosures. 

Sponsor: FIGS

Take 15% off your first order at Wearfigs.com with the code FIGSRX.

Sponsor: Continuing Education Company

Visit CMEmeeting.org/curbsiders and use promo code Curb30 for 30% off all online courses and webcasts. 

Sponsor: Mint Mobile
Shop Mint Unlimited Plans at . 

Blood-based Biomarkers, Anti-Amyloid Therapies and Beyond

From blood-based biomarkers to anti-amyloid treatments, join us as we explore the latest in Alzheimer’s disease diagnosis and treatment with Dr. Halima Amjad. This episode will equip you to guide your patients about the latest Alzheimer’s diagnostics as well as eligibility, risks and monitoring for anti-amyloid therapies.

Claim CME for this episode at !

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

• Intro
• Case
• Cognitive and functional history reminders
• Diagnosing Alzheimer’s Disease
• Blood-based biomarkers
• Anti-amyloid therapy indications, eligibility and contraindications
• Patient counseling and treatment decisions
• ARIA
• Key takeaways
• Outro

• Written and Produced by: Natalie Barrett DO, Rachel K Miller MD
• Show notes, cover art and infographic: Natalie Barrett DO, Rachel K Miller MD, Leah Witt MD
• Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
• Reviewer: Sai S Achi MD, MBA,FACP
• Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
• Technical Production: PodPaste
• Guest: Halima Amjad, MD

Disclosures

Dr. Amjad reports financial relationships with Centene (Advisor) and Craniometrix (Advisor). Relationships have not ended. The Curbsiders report no relevant financial disclosures. 

The production of this episode was supported by the Penn Geriatrics AGE-SMART Geriatric Workforce Enhancement Grant. This podcast content is solely the responsibility of the authors and does not necessarily represent the official views of the Health Resources and Services Administration or the U.S. Department of Health and Human Services. 

Sponsor: Babbel 

Right now get up to 55% off your Babbel subscription at Babbel.com/CURB.

Sponsor: Quince

Go to Quince.com/curb for free shipping on your order and 365-day returns. Now available in Canada, too.

Sponsor: Sanford Guide

Search for Sanford Guide in the app stores. And, Curbsiders listeners can get 20% off the already very moderately priced yearly subscriptions directly at sanfordguide.com. Go to sanfordguide.com and use the code, CURB at checkout.