A cancer diagnosis can be devastating. And the chemotherapy that often follows can be particularly rigorous. The American Cancer Society projects that 2.1 million people in the United States will be diagnosed with cancer in 2026—but researchers are making major advances in cancer treatment and patient survival.

Ziyang Zhang is a chemist and 2023 Pew-Stewart Scholar for Cancer Research who leads cutting-edge studies on reducing the negative effects of chemotherapy on cancer patients. In his lab at the University of California, Berkeley, he and his team are producing new tools at the chemical level that will help to develop more effective therapies to target cancer mutations and avoid damage to healthy cells.

Last year, a devastating and deadly fire in Milwaukee forced residents to confront a painful reality: The places where many people can afford to live are often the least safe. As the United States faces a shortage of millions of homes, new research shows that the path to safer, more affordable housing may lie in modern multifamily buildings that are constructed with fire-resistant materials like sprinkler systems and stronger building codes. In fact, the rate of fire death in modern apartments is one-sixth the rate of single-family houses and older apartment buildings.

In this episode of "After the Fact," Pew housing expert Alex Horowitz explains how modern housing design can save lives, and why public misconceptions about density and safety can limit progress. We also travel to Milwaukee to learn from firefighters on the ground about why better policy and smarter construction can help shape safer homes for the future.

Each January brings legislators back to their statehouses, where budget decisions once again take center stage. In the past few years, state budgets have been bolstered by leftover pandemic-era federal aid. In fact, in 2023, federal dollars made up about 36% of state revenue.

But in 2026, new federal policy changes are in play that will leave lawmakers with tough choices about how to balance their budgets and still fund the programs that serve their constituents.

In this episode of "After the Fact," Pew expert Liz Farmer shares the key financial issues states will face this year and how they could affect your community.

For the first time in history, the world has formally agreed to protect nearly half the planet. In September 2025, the United Nations ratified the high seas treaty, officially known as the Biodiversity Beyond National Jurisdiction (BBNJ) Agreement—a landmark global pact to safeguard the parts of the ocean that lie beyond any one country's national jurisdiction.

These vast waters—the high seas—cover nearly half of Earth's surface and sustain much of the life on our planet. Yet until now, they've been largely ungoverned, leaving marine ecosystems vulnerable to overfishing, pollution, and the growing impacts of climate change. In this episode of "After the Fact," Pew's director of ocean governance, Liz Karan, explains why this moment represents one of the most significant conservation milestones in decades—and what comes next.

In the heart of South America, the Chaco-Pantanal region holds the planet's largest tropical wetland. It's a place that's teeming with colorful birds, capybaras, anteaters, and even jaguars. Unlike the Amazon, this region has largely resisted deforestation, so conservation here is about preservation, not restoration. Take a trip with us in this episode of "After the Fact," in which Amelia Moura and Natalia Araujo, who work on Pew's conserving the Pantanal and Gran Chaco of South America project, describe what it's like to visit the Chaco-Pantanal; how Pew works alongside local communities to further conservation efforts; and why it's important to safeguard this region for the future.

As America approaches the 250th anniversary of its founding, Ken Burns offers the nation his latest documentary, "The American Revolution." In a conversation with "After the Fact," the acclaimed documentarian discusses the making of the six-part film, which premieres on PBS on Nov. 16.

He explains that the Revolution required the bringing together of people of all stripes, from farmers and shopkeepers to wealthy landowners, who, in rebelling against the British crown, not only were seeking redress of their grievances but also were becoming citizens, not subjects, for the first time in world history.

Burns invites us to reflect on what it means to be American and how the lessons of our revolutionary past can guide us toward a united future.

Millions of Americans are behind on their retirement savings goals, and nearly 70% of those already retired wish they had started saving earlier. But Gen Z, the latest generation to enter the workforce, is an outlier, with the data showing that they are saving more than millennials and putting new emphasis on planning for the future. What gives?

In this episode of "After the Fact," John Scott, who directs Pew's retirement savings project, explains new ways people can save more and earlier. And Taylor Price, a financial educator, influencer, and entrepreneur known online as Priceless Tay, discusses how she's trying to help close the financial literacy gap for Gen Zers.

While opioid use disorder dominates headlines, alcohol quietly remains America's most problematic—and overlooked—drug. Nearly 30 million people are estimated to have alcohol use disorder. In this episode of "After the Fact," Dr. Elizabeth Salisbury-Afshar, an addiction medicine specialist, and Pew's Frances McGaffey discuss the latest trends related to alcohol use, its normalization in American culture, and the evolving science behind its risks.

The ocean's coral reefs support an estimated 25% of all known marine life yet are threatened by rising ocean temperatures and bleaching. In this "After the Fact" episode from our recurring "From Lab to Life" series, we look at ways scientists are pioneering efforts to save corals.

Phillip Cleves is a marine scientist who researches ways to restore and protect these important ecosystems. From his lab at the Carnegie Institution for Science at Johns Hopkins University in Baltimore, he describes how studying coral genetics can help uncover solutions to protect marine health—and how this research can advance human health too.

As home prices continue to climb, many Americans are seeking more affordable options. And manufactured homes could be the solution. A new manufactured home installed on a foundation costs 35% to 73% as much as a similar site-built home. In this episode, Rachel Siegel from Pew's housing policy initiative explains the advantages of buying a manufactured home and debunks old stereotypes that inform the outdated zoning and titling laws that limit access to these types of houses.

The way Americans consume information is evolving fast, and younger Americans are increasingly turning to nontraditional sources for their news. According to Pew Research Center, 39% of adults under 30 regularly get their news from influencers rather than traditional outlets.

In this episode of "After the Fact," we explore what this shift means for trust in journalism, the role of social media in shaping public opinion, and how news organizations are responding to this changing landscape. Drawing on analysis from the Center and the Pew-Knight Initiative, we hear from a news researcher, Michael Lipka, and a content creator, Mosheh Oinounou, on how the lines between entertainment, opinion, and information are blurring, and what it means for the future of an informed public.