The U.S. is grappling with a recently discovered outbreak of avian influenza in dairy cows, driven by the highly pathogenic H5N1 virus. It's the first instance that the bird flu virus has been detected in US cattle. How concerned should we be about drinking milk or even eating chicken? And could this lead to the next pandemic? Sanjay speaks with epidemiologist Prof. Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota, about the complexities of the current outbreak and what the public needs to know right now.

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Global temperatures are rising, severe storms are intensifying and people are feeling climate anxiety. Does saving the planet mean living without comfort or convenience? Can policies and technology turn things around? CNN Chief Climate Correspondent, Bill Weir believes taking better care of the earth and our ourselves can go hand-in-hand. He talks with Dr. Sanjay Gupta about what’s working, what needs to change and why there is reason to be optimistic about the future. They also discuss Weir’s call to action - his new book, “Life as We Know It (Can Be): Stories of People, Climate and Hope in a Changing World.”

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For many of us, our weight and eating habits feel deeply intertwined. But how do you strike a balance between eating for pleasure and eating for fuel? How can we reframe our relationship with food – so it doesn't revolve around what’s “bad” or “good?” Sanjay speaks with Dr. Linda Shiue, an internal medicine physician, trained chef, and the author of Spicebox Kitchen. Dr. Shiue sheds light on sustainable approaches to healthy eating and we’ll hear from listeners about the foods that bring them joy.  

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When it comes to optimizing our mental and physical health, many of us focus on managing our weight and metabolic function. But what happens when the numbers are good but the way we feel about our bodies is bad? Should we be striving to love the way we look? Or is it better to not think about our bodies at all? Actress and activist, Jameela Jamil thinks a lot about health, food and diet culture. After years of struggling with anorexia, “The Good Place,” star and host of the "I Weigh with Jameela Jamil" podcast tells Sanjay why she thinks food, mental health, and body image are intertwined.

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Keto. High protein. Intermittent fasting. So many diets claim to be the best way to lose weight. But do diets actually work? Research shows that diets don’t lead to long-term weight loss for most people, and that even two people following the same “healthy” diet can have wildly different results. Stanford University nutrition professor Dr. Christopher Gardner has spent more than 20 years studying nutrition and comparing different diets. He spoke to CNN’s Chief Medical Correspondent Dr. Sanjay Gupta to share what he’s learned and shares his tips for personalizing the way you eat to fit your body’s needs. 

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There's no shortage of products and procedures promising a quick way to weight loss. But do they work? Or is it all just marketing and hype? In this episode, Sanjay speaks with Dr. Mikhail Varshavski – better known as Doctor Mike — who has made it his mission to debunk medical misinformation. He’ll dive into popular weight loss methods, how they supposedly work, and the truth behind cleanses, juices, tummy teas, and more.

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Thirteen years ago, Seattle-based writer Lindy West wrote an essay that took the internet by storm called “Hello, I’m Fat.” That essay would become the 2016 New York Times best-selling memoir, Shrill: Notes from a Loud Woman, and later a Hulu television series. On today’s episode, Lindy, who is still writing and hosts a podcast, sits down with CNN’s Chief Medical correspondent Dr. Sanjay Gupta for a candid and honest conversation about living as a self-described “fat” person, and how the way she thinks about weight has changed since writing Shrill. 

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How much do our genetics determine our destiny when it comes to how much we weigh? Cambridge geneticist Giles Yeo says your genes play a bigger role than you might think. “In casino terms, the house will always win if the die is weighted just a little bit one way versus the other.” On today’s Chasing Life, Professor Yeo, a pioneer in the field of obesity research, joins Dr. Sanjay Gupta to explain his ground-breaking research into why some people are genetically predisposed to eat more, and why it’s still so controversial to classify obesity as a “disease.” Plus, Professor Yeo shares how to treat and prevent obesity, a condition that impacts more than 40 percent of Americans, and counting.

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Weight gain is a common complaint among women in their 40s and 50s, with many blaming it on the ups and downs of menopause. But what exactly is the connection between menopause and weight gain? And can anything to be done to avoid it? In this episode, Sanjay speaks to Dr. Monica Christmas, the director of the menopause program at the University of Chicago Medicine and an associate professor of obstetrics and gynecology. She explains effective strategies for tackling midlife weight gain and shares practical advice on navigating this transformative phase with grace.

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Alabama’s Supreme Court has ruled that embryos are children and anyone discarding frozen embryos could face wrongful death charges. So where does this leave fertility doctors and their patients in the state? And could this ruling have national implications? For this special episode, Dr. Sanjay Gupta turns to IVF expert, Dr. Eve Feinberg from the Feinberg School of Medicine at Northwestern University. She explains how embryos are handled during the IVF process and why the ruling is contentious for fertility care providers. Also, CNN Correspondent Isabel Rosales shares how some families and fertility clinics in Alabama have responded.

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Children and adolescents are expected to gain weight as they age, but how much is too much? Childhood obesity rates are on the rise, along with disordered eating among teens. So how can kids and their parents address this head on? Dr. Jack Yanovski, a pediatric endocrinologist at the National Institute of Child Health and Human Development recommends first determining who is most concerned about the weight. From there, he tells Sanjay about the causes and consequences of high body weight in kids, as well as treatment options – which include weight loss medications for children as young as 12. Dr. Yanovski also offers guidance on how to talk to kids about food and weight.

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