Triangulation (Video HD)

Every week TWiT hosts talk to the smartest people in the world about the most important topics in technology. Join Leo Laporte, Jason Howell, Mikah Sargent, or Denise Howell for these enlightening one-on-one interviews.

  • 1 hour 24 seconds
    Triangulation 433: The Father of Modern Genomics - George Church

    In a wide-ranging conversation, Leo Laporte talks with Dr. George Church about the history and future of genome sequencing. Dr. Church explains why he is very excited about how they made an organism resistant to all viruses- both known and unknown.

    They also talk about:

    • How Dr. Church made sequencing affordable (from $3BN to $600)
    • Where are we on sequencing the entire human genome, and why would we even want to?
    • How close are we to reversing aging?
    • Should we use gene therapy to double the human lifespan?
    • Why genetically engineering cold-resistant elephants could be important for climate change, and what about ultimately bringing back the Mammoth?
    • He explains the difference between the hype and reality of CRISPR
    • sequencing, synthesis, and delivery
    • What are the privacy concerns about companies sharing your genome?
    • They discuss the controversy and benefit of reconstructing old viruses like the 1918 flu and even inventing new viruses.

    Dr. Church is a professor of genetics at Harvard Medical School and a pioneer in personal genetics. He is credited with developing the first methods for sequencing the first genome and also the CRISPR technology. He created several companies, including Nebula Genomics and Veritas Genetics.

    Host: Leo Laporte

    Guest: Dr. George Church

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    3 March 2023, 7:45 pm
  • 1 hour 18 minutes
    Triangulation 432: Daniel Suarez: Critical Mass - Daniel Suarez on his latest book 'Critical Mass'

    New York Times bestselling author Daniel Suarez returns to talk with Leo Laporte about the second book in his 'Delta-v' novel series, 'Critical Mass,' where a group of pioneering astropreneurs must overcome never-before-attempted engineering challenges to rescue colleagues stranded at a distant asteroid—kicking off a new space race in which Earth's climate crisis could well hang in the balance.

    Get 'Critical Mass': https://amzn.to/3Yjb9xu

    Host: Leo Laporte

    Guest: Daniel Suarez

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    10 February 2023, 11:33 pm
  • 1 hour 4 minutes
    Triangulation 431: Cory Doctorow and Rebecca Giblin: Chokepoint Capitalism - How Big Tech and Big Content Captured Creative Labor Markets and How We'll Win Them Back

    Writer/activist Cory Doctorow and scholar Rebecca Giblin join Leo Laporte to talk about their latest book Chokepoint Capitalism: How Big Tech and Big Content Captured Creative Labor Markets and How We'll Win Them Back. They argue that we're in a new era of "chokepoint capitalism," with exploitative businesses creating insurmountable barriers to competition that enable them to capture value that should rightfully go to others.

    Get "Chokepoint Capitalism": https://chokepointcapitalism.com

    Host: Leo Laporte

    Guests: Cory Doctorow and Rebecca Giblin

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    30 September 2022, 1:02 am
  • 57 minutes 31 seconds
    Triangulation 430: Tripp Mickle: After Steve - A Conversation with Tripp Mickle

    Tripp Mickle joins Leo Laporte to discuss his new book, "After Steve: How Apple Became a Trillion-Dollar Company and Lost Its Soul". They discuss the shift in Apple's dynamic and approach to products after the passing of Steve Jobs from a company of innovation with Jony Ive, to a company of efficiency under Tim Cook.

    Host: Leo Laporte

    Guest: Tripp Mickle

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    20 May 2022, 12:44 am
  • 1 hour 3 minutes
    Triangulation 429: Amy Webb: The Genesis Machine - Looking to the future through the lens of synthetic biology.

    Amy Webb joins Leo Laporte to discuss her new book, "The Genesis Machine." Webb explains synthetic biology, tells the story of golden rice, and shares a glimpse of the future and the changes we can expect.

    Get "The Genesis Machine": https://amzn.to/3BC7K2t

    Host: Leo Laporte

    Guest: Amy Webb

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    20 February 2022, 3:59 am
  • 1 hour 10 minutes
    Triangulation 428: Andy Weir's "Project Hail Mary" - A conversation with science-fiction author, Andy Weir

    Leo Laporte interviews Andy Weir, author of "The Martian," about his new book, "Project Hail Mary." The discussion starts out spoiler-free with a chat about making the book into a film, how Andy Weir approached writing this book, and the time he confused Ryan Reynolds and Ryan Gosling. After a loud and apparent spoiler warning (at 32:04), the two continue their chat by discussing "Project Hail Mary" in depth. Weir shares a bit about the science behind the book, the characters he's created, and other stories he's working on.

    Project Hail Mary: https://amzn.to/3hLcStp
    The Martian: https://amzn.to/3v9LUiU
    Artemis: https://amzn.to/3vahYDf

    Host: Leo Laporte

    Guest: Andy Weir

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    22 May 2021, 3:18 am
  • 1 hour 19 minutes
    Triangulation 427: Jeff Brockman - Prog rock drummer of CAIRO and Virtual Live Show; and Studio Engineer at TWiT.

    Jason Howell is joined by TWiT's studio engineer to talk about his time as the drummer and founder of the progressive rock band Cairo, creating the Virtual Live Show, and how the intersection of music and tech has evolved.

    Cairo on YouTube: https://www.youtube.com/JeffBrockmanDirector

    Virtual Live Show on Twitter: https://twitter.com/virtualliveshow

    Host: Jason Howell

    Guest: Jeff Brockman

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    27 December 2019, 1:30 pm
  • 48 minutes 18 seconds
    Triangulation 426: Flynn Coleman: A Human Algorithm - How Artificial Intelligence Is Redefining Who We Are

    Flynn Coleman, writer, and international human rights attorney, joins Denise Howell to talk about her book A Human Algorithm: How Artificial Intelligence Is Redefining Who We Are. Flynn argues that we must instill values, ethics, and morals into our robots, algorithms, and other forms of AI by developing and implement laws, policies, and oversight mechanisms to protect us from tech's insidious threats.

    Get "A Human Algorithm": https://amzn.to/2rIqgH6

    Host: Denise Howell

    Guest: Flynn Coleman

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    20 December 2019, 9:22 pm
  • 1 hour 33 minutes
    Triangulation 425: Stephen Wolfram: Adventures of a Computational Explorer

    Stephen Wolfram is a computer scientist who designed Mathematica, Wolfram Alpha, and the Wolfram Language. He talks to Mikah Sargent about translating between human language, mathematics, and programming languages, how computational language works, and how he has spent his life trying to build computational intelligence up.

    Host: Mikah Sargent

    Guest: Stephen Wolfram

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    Sponsors:

    14 December 2019, 1:32 am
  • 1 hour 11 minutes
    Triangulation 424: Margaret O'Mara: The Code - Silicon Valley and the Remaking of America

    Margaret O'Mara, Professor of History at the University of Washington, joins Mikah Sargent to talk about her book The Code: Silicon Valley and the Remaking of America. They dive into the behind-the-scenes history of Silicon Valley, including how the Cold War shaped what Stanford University is today, shine a light on some of the unsung heroes like Ann Hardy and David Morgenthaler, and the legacy of Steve Jobs.

    Get "The Code": https://amzn.to/32ozIwm

    Host: Mikah Sargent

    Guest: Margaret O'Mara

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    Sponsor:

    6 December 2019, 10:27 pm
  • 1 hour 4 minutes
    Triangulation 423: Scott Petry, CEO of Authentic8

    Scott Petry is the CEO of Authentic8. He talks to Leo Laporte about his work on the Newton, how he saved the world from spam, and his plan to make your browser safe.

    Host: Leo Laporte

    Guest: Scott Petry

    Download or subscribe to this show at https://twit.tv/shows/triangulation.

    22 November 2019, 10:57 pm
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